Rattus norvegicus

22 known processes

Gtf2i

general transcription factor II I

(Aliases: Gtf2ird1,MGC94055)

Gtf2i biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of metabolic process GO:0009892 331 0.144
negative regulation of gene expression GO:0010629 199 0.132
transcription from rna polymerase ii promoter GO:0006366 252 0.122
regulation of cellular component organization GO:0051128 368 0.107
oxoacid metabolic process GO:0043436 290 0.107
regulation of neuron projection development GO:0010975 161 0.105
negative regulation of macromolecule metabolic process GO:0010605 260 0.102
cellular component assembly GO:0022607 360 0.100
nucleic acid templated transcription GO:0097659 379 0.092
positive regulation of developmental process GO:0051094 283 0.090
positive regulation of neuron projection development GO:0010976 99 0.089
regulation of programmed cell death GO:0043067 341 0.087
cellular component biogenesis GO:0044085 368 0.085
rna biosynthetic process GO:0032774 380 0.083
regulation of molecular function GO:0065009 398 0.082
regulation of cell development GO:0060284 263 0.072
cellular amino acid metabolic process GO:0006520 107 0.072
macromolecular complex assembly GO:0065003 273 0.071
organelle organization GO:0006996 266 0.071
dna modification GO:0006304 12 0.071
regulation of protein modification process GO:0031399 194 0.070
carboxylic acid metabolic process GO:0019752 289 0.069
neuron differentiation GO:0030182 368 0.069
regulation of apoptotic process GO:0042981 335 0.068
cellular response to stress GO:0033554 269 0.067
macromolecular complex subunit organization GO:0043933 339 0.063
programmed cell death GO:0012501 392 0.063
regulation of neuron differentiation GO:0045664 208 0.062
purine containing compound metabolic process GO:0072521 253 0.062
amine metabolic process GO:0009308 38 0.061
regulation of phosphorus metabolic process GO:0051174 349 0.059
regulation of transcription dna templated GO:0006355 374 0.059
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.059
protein complex biogenesis GO:0070271 263 0.058
carbohydrate derivative metabolic process GO:1901135 346 0.058
protein complex assembly GO:0006461 263 0.058
regulation of multicellular organismal development GO:2000026 376 0.057
Human
cell migration GO:0016477 197 0.057
negative regulation of rna metabolic process GO:0051253 123 0.055
central nervous system development GO:0007417 311 0.055
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.055
regulation of neurogenesis GO:0050767 247 0.055
negative regulation of cellular biosynthetic process GO:0031327 161 0.055
organic acid metabolic process GO:0006082 292 0.054
response to extracellular stimulus GO:0009991 380 0.053
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.052
response to peptide GO:1901652 292 0.051
negative regulation of cellular metabolic process GO:0031324 281 0.051
regulation of nervous system development GO:0051960 264 0.051
neuron development GO:0048666 286 0.050
limbic system development GO:0021761 38 0.050
cell projection organization GO:0030030 302 0.050
positive regulation of multicellular organismal process GO:0051240 387 0.049
catabolic process GO:0009056 351 0.048
cellular macromolecule localization GO:0070727 122 0.047
protein complex subunit organization GO:0071822 302 0.047
homeostatic process GO:0042592 331 0.047
growth GO:0040007 165 0.047
regulation of rna biosynthetic process GO:2001141 381 0.046
positive regulation of cellular component organization GO:0051130 200 0.046
single organism intracellular transport GO:1902582 166 0.046
cellular amine metabolic process GO:0044106 38 0.046
cellular component movement GO:0006928 248 0.045
neuron apoptotic process GO:0051402 88 0.044
cell morphogenesis involved in differentiation GO:0000904 119 0.044
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.044
positive regulation of neurogenesis GO:0050769 165 0.044
cell cycle GO:0007049 101 0.044
negative regulation of biosynthetic process GO:0009890 168 0.044
positive regulation of cell differentiation GO:0045597 217 0.044
positive regulation of biosynthetic process GO:0009891 319 0.043
brain development GO:0007420 247 0.043
positive regulation of protein modification process GO:0031401 142 0.043
negative regulation of signal transduction GO:0009968 83 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.041
regulation of cellular amino acid metabolic process GO:0006521 2 0.041
regulation of phosphorylation GO:0042325 248 0.041
dna methylation or demethylation GO:0044728 8 0.041
axonogenesis GO:0007409 71 0.040
positive regulation of molecular function GO:0044093 230 0.040
histone h3 acetylation GO:0043966 2 0.039
positive regulation of cell projection organization GO:0031346 111 0.039
regulation of nucleic acid templated transcription GO:1903506 380 0.038
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.038
positive regulation of cell development GO:0010720 176 0.038
glycosyl compound metabolic process GO:1901657 182 0.038
macromolecule localization GO:0033036 252 0.038
embryonic hindlimb morphogenesis GO:0035116 2 0.038
response to growth factor GO:0070848 189 0.037
regulation of cellular amine metabolic process GO:0033238 8 0.036
forebrain development GO:0030900 98 0.036
negative regulation of cell proliferation GO:0008285 119 0.036
response to peptide hormone GO:0043434 278 0.036
purine ribonucleotide metabolic process GO:0009150 227 0.036
protein oligomerization GO:0051259 191 0.036
transcription dna templated GO:0006351 377 0.035
ribonucleotide metabolic process GO:0009259 231 0.035
positive regulation of cellular protein metabolic process GO:0032270 167 0.034
regulation of cell projection organization GO:0031344 175 0.034
chromosome segregation GO:0007059 2 0.034
regulation of cellular response to stress GO:0080135 49 0.034
intracellular transport GO:0046907 185 0.033
positive regulation of cellular amine metabolic process GO:0033240 3 0.033
negative regulation of transcription dna templated GO:0045892 116 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.033
positive regulation of nervous system development GO:0051962 178 0.033
regulation of rna metabolic process GO:0051252 391 0.032
spindle organization GO:0007051 2 0.032
positive regulation of protein metabolic process GO:0051247 178 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.032
cellular ketone metabolic process GO:0042180 51 0.032
dna metabolic process GO:0006259 96 0.032
cellular response to growth factor stimulus GO:0071363 162 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
negative regulation of cell death GO:0060548 229 0.030
regulation of neuron death GO:1901214 115 0.030
intracellular signal transduction GO:0035556 314 0.030
nucleotide metabolic process GO:0009117 279 0.030
regulation of blood vessel endothelial cell migration GO:0043535 4 0.030
carbohydrate metabolic process GO:0005975 130 0.030
purine ribonucleoside metabolic process GO:0046128 168 0.029
ribonucleoside metabolic process GO:0009119 174 0.029
regulation of cell growth GO:0001558 85 0.029
negative regulation of multicellular organismal process GO:0051241 203 0.029
Human
single organism carbohydrate metabolic process GO:0044723 118 0.029
regulation of catalytic activity GO:0050790 304 0.029
rna metabolic process GO:0016070 406 0.029
cellular response to extracellular stimulus GO:0031668 73 0.029
anatomical structure morphogenesis GO:0009653 298 0.028
Human
cell type specific apoptotic process GO:0097285 134 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
limb morphogenesis GO:0035108 4 0.028
negative regulation of rna biosynthetic process GO:1902679 118 0.028
regulation of protein metabolic process GO:0051246 289 0.028
neuron projection morphogenesis GO:0048812 122 0.028
negative regulation of viral process GO:0048525 4 0.028
vasculogenesis GO:0001570 3 0.028
cellular chemical homeostasis GO:0055082 247 0.028
positive regulation of phosphorylation GO:0042327 177 0.028
artery development GO:0060840 3 0.027
protein autophosphorylation GO:0046777 66 0.027
blood vessel development GO:0001568 69 0.027
Human
ribose phosphate metabolic process GO:0019693 235 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
immune system process GO:0002376 204 0.027
purine nucleoside metabolic process GO:0042278 169 0.027
cellular response to external stimulus GO:0071496 118 0.027
regulation of dna metabolic process GO:0051052 60 0.027
axon development GO:0061564 96 0.027
apoptotic process GO:0006915 381 0.027
gastrulation GO:0007369 2 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.027
negative regulation of programmed cell death GO:0043069 183 0.026
positive regulation of neuron differentiation GO:0045666 126 0.026
locomotion GO:0040011 237 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.025
biological adhesion GO:0022610 110 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
regulation of protein phosphorylation GO:0001932 183 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.025
telencephalon development GO:0021537 62 0.025
head development GO:0060322 247 0.025
regulation of cell differentiation GO:0045595 320 0.025
negative regulation of apoptotic process GO:0043066 181 0.025
cell part morphogenesis GO:0032990 123 0.024
neuron projection development GO:0031175 273 0.024
positive regulation of gene expression GO:0010628 244 0.024
reproductive system development GO:0061458 128 0.024
cellular response to oxygen containing compound GO:1901701 386 0.024
negative regulation of nucleic acid templated transcription GO:1903507 117 0.023
negative regulation of cell cycle phase transition GO:1901988 4 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
Human
regulation of cell proliferation GO:0042127 359 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
negative regulation of protein metabolic process GO:0051248 114 0.023
establishment of protein localization GO:0045184 141 0.023
taxis GO:0042330 67 0.023
pallium development GO:0021543 42 0.023
cellular protein localization GO:0034613 122 0.022
regulation of kinase activity GO:0043549 117 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
positive regulation of cell growth GO:0030307 44 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
positive regulation of growth GO:0045927 55 0.021
regeneration GO:0031099 163 0.021
negative regulation of cell communication GO:0010648 158 0.021
appendage morphogenesis GO:0035107 4 0.021
vasculature development GO:0001944 70 0.021
Human
gland development GO:0048732 155 0.020
negative regulation of signaling GO:0023057 157 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
nucleoside metabolic process GO:0009116 179 0.020
protein localization GO:0008104 191 0.020
cell projection morphogenesis GO:0048858 123 0.020
peptidyl amino acid modification GO:0018193 126 0.020
multi organism reproductive process GO:0044703 262 0.020
heterocycle catabolic process GO:0046700 167 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
negative regulation of developmental process GO:0051093 125 0.019
Human
cell growth GO:0016049 104 0.019
aromatic compound catabolic process GO:0019439 168 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
tissue development GO:0009888 252 0.019
neuromuscular process GO:0050905 2 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
regulation of histone h3 k9 methylation GO:0051570 1 0.019
regulation of gene expression epigenetic GO:0040029 10 0.018
response to ketone GO:1901654 182 0.018
regulation of signal transduction GO:0009966 318 0.018
nitrogen compound transport GO:0071705 229 0.018
chemotaxis GO:0006935 66 0.018
developmental process involved in reproduction GO:0003006 159 0.018
regulation of cytokine biosynthetic process GO:0042035 3 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.018
embryonic appendage morphogenesis GO:0035113 4 0.018
protein phosphorylation GO:0006468 345 0.018
development of primary sexual characteristics GO:0045137 107 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.017
negative regulation of cellular component organization GO:0051129 83 0.017
negative regulation of cell differentiation GO:0045596 99 0.017
multicellular organism reproduction GO:0032504 233 0.017
cell fate determination GO:0001709 2 0.017
regulation of protein kinase activity GO:0045859 105 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
cellular catabolic process GO:0044248 295 0.017
regulation of cell motility GO:2000145 131 0.017
reproductive process GO:0022414 372 0.017
cell adhesion GO:0007155 110 0.016
neuron death GO:0070997 127 0.016
cell cycle checkpoint GO:0000075 2 0.016
ribonucleoside triphosphate catabolic process GO:0009203 122 0.016
eye development GO:0001654 50 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
regulation of heterotypic cell cell adhesion GO:0034114 2 0.016
reproductive structure development GO:0048608 128 0.016
double strand break repair GO:0006302 1 0.016
cytokine biosynthetic process GO:0042089 3 0.016
cellular response to lipid GO:0071396 201 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
response to organophosphorus GO:0046683 102 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
single organism biosynthetic process GO:0044711 342 0.015
ion homeostasis GO:0050801 212 0.015
regulation of neuron apoptotic process GO:0043523 83 0.015
regulation of cell migration GO:0030334 128 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
mitotic spindle organization GO:0007052 2 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
single organism catabolic process GO:0044712 283 0.015
anterior posterior pattern specification GO:0009952 1 0.015
dna integrity checkpoint GO:0031570 2 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
chromatin assembly or disassembly GO:0006333 1 0.015
developmental growth GO:0048589 100 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
molting cycle GO:0042303 3 0.015
response to acid chemical GO:0001101 222 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
cytoplasmic transport GO:0016482 115 0.014
hair cycle GO:0042633 3 0.014
protein maturation GO:0051604 68 0.014
regulation of locomotion GO:0040012 148 0.014
dendrite morphogenesis GO:0048813 43 0.014
negative regulation of molecular function GO:0044092 133 0.014
sensory perception GO:0007600 101 0.014
cyclic purine nucleotide metabolic process GO:0052652 62 0.014
regulation of hydrolase activity GO:0051336 143 0.014
eye morphogenesis GO:0048592 4 0.014
alcohol metabolic process GO:0006066 77 0.014
vesicle mediated transport GO:0016192 181 0.014
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
response to vitamin GO:0033273 131 0.013
nucleoside catabolic process GO:0009164 126 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
cellular cation homeostasis GO:0030003 180 0.013
chromosome organization GO:0051276 36 0.013
organophosphate metabolic process GO:0019637 370 0.013
multi multicellular organism process GO:0044706 138 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
response to nutrient levels GO:0031667 370 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
single organism reproductive process GO:0044702 297 0.013
sex differentiation GO:0007548 113 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.013
regulation of cellular localization GO:0060341 263 0.013
cell motility GO:0048870 202 0.013
response to carbohydrate GO:0009743 183 0.013
regulation of cell cycle g1 s phase transition GO:1902806 7 0.013
neurological system process GO:0050877 219 0.013
response to hexose GO:0009746 144 0.013
viral transcription GO:0019083 2 0.013
regulation of response to stress GO:0080134 126 0.013
multicellular organism growth GO:0035264 1 0.013
cell cycle g1 s phase transition GO:0044843 13 0.013
nuclear transport GO:0051169 49 0.012
single organism organelle organization GO:1902589 180 0.012
organic substance catabolic process GO:1901575 316 0.012
chemical homeostasis GO:0048878 292 0.012
regulation of transferase activity GO:0051338 123 0.012
rna catabolic process GO:0006401 3 0.012
regulation of protein maturation GO:1903317 50 0.012
rna localization GO:0006403 4 0.012
cellular homeostasis GO:0019725 252 0.012
ras protein signal transduction GO:0007265 29 0.012
organophosphate catabolic process GO:0046434 148 0.012
cellular response to acid chemical GO:0071229 75 0.012
response to ethanol GO:0045471 162 0.012
regulation of cellular component movement GO:0051270 150 0.012
negative regulation of transport GO:0051051 136 0.012
negative regulation of endopeptidase activity GO:0010951 36 0.012
neuron projection guidance GO:0097485 24 0.012
dna packaging GO:0006323 4 0.012
dna alkylation GO:0006305 8 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
protein modification by small protein conjugation or removal GO:0070647 35 0.012
cellular protein complex assembly GO:0043623 44 0.012
hair cycle process GO:0022405 2 0.012
cellular component morphogenesis GO:0032989 155 0.012
gamete generation GO:0007276 124 0.011
protein processing GO:0016485 68 0.011
proteolysis GO:0006508 175 0.011
macromolecule methylation GO:0043414 16 0.011
hippocampus development GO:0021766 30 0.011
regulation of intracellular transport GO:0032386 65 0.011
response to external biotic stimulus GO:0043207 221 0.011
synaptic transmission GO:0007268 235 0.011
cardiovascular system development GO:0072358 134 0.011
Human
histone methylation GO:0016571 3 0.011
hair cell differentiation GO:0035315 2 0.011
regulation of mitotic cell cycle phase transition GO:1901990 11 0.011
regulation of growth GO:0040008 105 0.011
localization of cell GO:0051674 202 0.011
protein sumoylation GO:0016925 4 0.011
skin morphogenesis GO:0043589 2 0.011
purine containing compound catabolic process GO:0072523 138 0.011
cellular ion homeostasis GO:0006873 184 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
circulatory system development GO:0072359 134 0.011
Human
blood circulation GO:0008015 183 0.011
histone h3 k9 methylation GO:0051567 1 0.011
response to biotic stimulus GO:0009607 226 0.011
axis specification GO:0009798 4 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
response to axon injury GO:0048678 59 0.011
epithelial cell proliferation GO:0050673 54 0.011
immune response GO:0006955 104 0.011
developmental growth involved in morphogenesis GO:0060560 33 0.011
monoamine transport GO:0015844 43 0.011
protein localization to organelle GO:0033365 57 0.011
regulation of protein processing GO:0070613 50 0.011
mitotic cell cycle GO:0000278 49 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
visual perception GO:0007601 3 0.011
cell morphogenesis GO:0000902 142 0.010
negative regulation of cell cycle g1 s phase transition GO:1902807 2 0.010
response to testosterone GO:0033574 55 0.010
negative regulation of neuron death GO:1901215 69 0.010
learning or memory GO:0007611 90 0.010
behavior GO:0007610 205 0.010
glycosyl compound catabolic process GO:1901658 126 0.010
regulation of membrane potential GO:0042391 110 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
reproduction GO:0000003 245 0.010
regulation of cell cycle GO:0051726 73 0.010
regulation of anatomical structure size GO:0090066 135 0.010
amide biosynthetic process GO:0043604 10 0.010
regulation of metal ion transport GO:0010959 118 0.010
cell cell signaling GO:0007267 335 0.010
embryonic pattern specification GO:0009880 1 0.010

Gtf2i disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
musculoskeletal system disease DOID:17 0 0.016