Rattus norvegicus

87 known processes

Sin3a

SIN3 homolog A, transcription regulator (yeast)

Sin3a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.089
regulation of transcription dna templated GO:0006355 374 0.081
transcription from rna polymerase ii promoter GO:0006366 252 0.074
regulation of rna biosynthetic process GO:2001141 381 0.067
negative regulation of rna biosynthetic process GO:1902679 118 0.060
negative regulation of nucleic acid templated transcription GO:1903507 117 0.056
transcription dna templated GO:0006351 377 0.055
regulation of cell proliferation GO:0042127 359 0.053
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.050
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.048
negative regulation of metabolic process GO:0009892 331 0.048
intracellular signal transduction GO:0035556 314 0.045
protein phosphorylation GO:0006468 345 0.043
response to extracellular stimulus GO:0009991 380 0.042
rna biosynthetic process GO:0032774 380 0.042
rna metabolic process GO:0016070 406 0.040
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.039
regulation of nucleic acid templated transcription GO:1903506 380 0.038
positive regulation of cellular biosynthetic process GO:0031328 295 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.037
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
nucleic acid templated transcription GO:0097659 379 0.035
regulation of phosphorus metabolic process GO:0051174 349 0.034
regulation of cell differentiation GO:0045595 320 0.033
apoptotic process GO:0006915 381 0.032
positive regulation of biosynthetic process GO:0009891 319 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
neuron differentiation GO:0030182 368 0.031
central nervous system development GO:0007417 311 0.030
cellular component biogenesis GO:0044085 368 0.029
cellular response to stress GO:0033554 269 0.029
negative regulation of biosynthetic process GO:0009890 168 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
positive regulation of signaling GO:0023056 270 0.027
single organism organelle organization GO:1902589 180 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
positive regulation of signal transduction GO:0009967 175 0.027
histone h3 acetylation GO:0043966 2 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
regulation of programmed cell death GO:0043067 341 0.025
regulation of protein metabolic process GO:0051246 289 0.025
dna metabolic process GO:0006259 96 0.025
response to nutrient levels GO:0031667 370 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
response to nutrient GO:0007584 248 0.024
response to ethanol GO:0045471 162 0.024
cellular amino acid metabolic process GO:0006520 107 0.023
organelle organization GO:0006996 266 0.023
neurological system process GO:0050877 219 0.023
nucleotide metabolic process GO:0009117 279 0.023
regulation of cell development GO:0060284 263 0.023
positive regulation of cell communication GO:0010647 271 0.023
programmed cell death GO:0012501 392 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
single organism catabolic process GO:0044712 283 0.023
anterior posterior pattern specification GO:0009952 1 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.022
cellular component assembly GO:0022607 360 0.022
brain development GO:0007420 247 0.022
cellular amine metabolic process GO:0044106 38 0.022
organic acid metabolic process GO:0006082 292 0.022
cell migration GO:0016477 197 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
purine containing compound metabolic process GO:0072521 253 0.022
chromatin organization GO:0006325 34 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
positive regulation of cell differentiation GO:0045597 217 0.021
response to decreased oxygen levels GO:0036293 237 0.021
regulation of nervous system development GO:0051960 264 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
negative regulation of developmental process GO:0051093 125 0.021
response to acid chemical GO:0001101 222 0.021
oxoacid metabolic process GO:0043436 290 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.020
response to vitamin GO:0033273 131 0.020
regulation of neurogenesis GO:0050767 247 0.020
chemical homeostasis GO:0048878 292 0.020
positive regulation of response to stimulus GO:0048584 285 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
regulation of apoptotic process GO:0042981 335 0.020
head development GO:0060322 247 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
positive regulation of developmental process GO:0051094 283 0.020
regulation of molecular function GO:0065009 398 0.020
negative regulation of transcription dna templated GO:0045892 116 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
positive regulation of gene expression GO:0010628 244 0.019
amine metabolic process GO:0009308 38 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
regulation of membrane potential GO:0042391 110 0.019
organophosphate metabolic process GO:0019637 370 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
chromosome segregation GO:0007059 2 0.019
cell projection organization GO:0030030 302 0.019
cellular ketone metabolic process GO:0042180 51 0.019
reproductive process GO:0022414 372 0.019
regulation of signal transduction GO:0009966 318 0.018
macromolecular complex assembly GO:0065003 273 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
negative regulation of gene expression GO:0010629 199 0.018
homeostatic process GO:0042592 331 0.018
cellular homeostasis GO:0019725 252 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
positive regulation of cell death GO:0010942 184 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
positive regulation of nervous system development GO:0051962 178 0.017
neuron projection development GO:0031175 273 0.017
positive regulation of molecular function GO:0044093 230 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
regulation of multicellular organismal development GO:2000026 376 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
positive regulation of apoptotic process GO:0043065 154 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
cellular response to endogenous stimulus GO:0071495 377 0.016
chromosome organization GO:0051276 36 0.016
single organism reproductive process GO:0044702 297 0.016
protein complex biogenesis GO:0070271 263 0.016
regulation of protein modification process GO:0031399 194 0.016
cation transport GO:0006812 382 0.016
chromatin modification GO:0016568 33 0.016
eye morphogenesis GO:0048592 4 0.016
nucleoside metabolic process GO:0009116 179 0.016
nucleotide catabolic process GO:0009166 139 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.015
response to oxygen levels GO:0070482 265 0.015
multicellular organism reproduction GO:0032504 233 0.015
locomotion GO:0040011 237 0.015
protein complex subunit organization GO:0071822 302 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
cellular chemical homeostasis GO:0055082 247 0.015
muscle system process GO:0003012 115 0.015
cellular component movement GO:0006928 248 0.015
protein deubiquitination GO:0016579 4 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
neuron development GO:0048666 286 0.015
regulation of phosphorylation GO:0042325 248 0.015
response to inorganic substance GO:0010035 377 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
embryonic pattern specification GO:0009880 1 0.015
positive regulation of cell development GO:0010720 176 0.015
axis specification GO:0009798 4 0.015
multicellular organismal signaling GO:0035637 44 0.015
positive regulation of phosphorylation GO:0042327 177 0.014
catabolic process GO:0009056 351 0.014
regulation of cellular component organization GO:0051128 368 0.014
regulation of catalytic activity GO:0050790 304 0.014
peptidyl amino acid modification GO:0018193 126 0.014
cell type specific apoptotic process GO:0097285 134 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
protein complex assembly GO:0006461 263 0.014
cellular component morphogenesis GO:0032989 155 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
ras protein signal transduction GO:0007265 29 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
negative regulation of cell death GO:0060548 229 0.014
ion transmembrane transport GO:0034220 365 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
cellular catabolic process GO:0044248 295 0.013
cell cell signaling GO:0007267 335 0.013
regulation of transferase activity GO:0051338 123 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
response to radiation GO:0009314 137 0.013
secretion GO:0046903 307 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
response to growth factor GO:0070848 189 0.013
regulation of neuron differentiation GO:0045664 208 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
response to hypoxia GO:0001666 231 0.012
single organism biosynthetic process GO:0044711 342 0.012
protein localization GO:0008104 191 0.012
single organism cellular localization GO:1902580 102 0.012
behavior GO:0007610 205 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
tissue development GO:0009888 252 0.012
cell motility GO:0048870 202 0.012
chromatin assembly or disassembly GO:0006333 1 0.012
cellular response to lipid GO:0071396 201 0.012
cation homeostasis GO:0055080 195 0.012
multi organism reproductive process GO:0044703 262 0.012
heterocycle catabolic process GO:0046700 167 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
regulation of kinase activity GO:0043549 117 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
response to carbohydrate GO:0009743 183 0.012
response to ketone GO:1901654 182 0.012
localization of cell GO:0051674 202 0.012
response to metal ion GO:0010038 253 0.012
histone modification GO:0016570 30 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
transmembrane transport GO:0055085 412 0.011
lens fiber cell differentiation GO:0070306 3 0.011
response to ionizing radiation GO:0010212 59 0.011
negative regulation of signaling GO:0023057 157 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
neuron projection morphogenesis GO:0048812 122 0.011
calcium ion homeostasis GO:0055074 162 0.011
negative regulation of cell communication GO:0010648 158 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
muscle structure development GO:0061061 87 0.011
lipid storage GO:0019915 1 0.011
cell morphogenesis GO:0000902 142 0.011
regulation of locomotion GO:0040012 148 0.011
rho protein signal transduction GO:0007266 11 0.011
camera type eye morphogenesis GO:0048593 2 0.011
regulation of neuron projection development GO:0010975 161 0.011
gamete generation GO:0007276 124 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
growth GO:0040007 165 0.011
macromolecule localization GO:0033036 252 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
positive regulation of protein modification process GO:0031401 142 0.011
cellular macromolecule localization GO:0070727 122 0.011
protein oligomerization GO:0051259 191 0.011
cellular ion homeostasis GO:0006873 184 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
hepaticobiliary system development GO:0061008 90 0.011
cellular response to external stimulus GO:0071496 118 0.011
ribonucleotide catabolic process GO:0009261 136 0.010
action potential GO:0001508 54 0.010
response to peptide GO:1901652 292 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
metal ion homeostasis GO:0055065 186 0.010
organ regeneration GO:0031100 101 0.010
response to estradiol GO:0032355 164 0.010
intracellular transport GO:0046907 185 0.010
regulation of cellular localization GO:0060341 263 0.010
response to estrogen GO:0043627 232 0.010
anion transport GO:0006820 178 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
response to monosaccharide GO:0034284 159 0.010
covalent chromatin modification GO:0016569 30 0.010
spermatogenesis GO:0007283 99 0.010
actin filament based process GO:0030029 86 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
transmission of nerve impulse GO:0019226 42 0.010
male gamete generation GO:0048232 99 0.010
regeneration GO:0031099 163 0.010

Sin3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.012
central nervous system disease DOID:331 0 0.010