Rattus norvegicus

7 known processes

Lrrtm2

leucine rich repeat transmembrane neuronal 2

Lrrtm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient levels GO:0031667 370 0.047
response to extracellular stimulus GO:0009991 380 0.046
organic acid metabolic process GO:0006082 292 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.042
oxoacid metabolic process GO:0043436 290 0.040
regulation of rna metabolic process GO:0051252 391 0.040
nucleic acid templated transcription GO:0097659 379 0.040
programmed cell death GO:0012501 392 0.039
rna metabolic process GO:0016070 406 0.039
rna biosynthetic process GO:0032774 380 0.039
cellular amino acid metabolic process GO:0006520 107 0.039
carboxylic acid metabolic process GO:0019752 289 0.039
regulation of multicellular organismal development GO:2000026 376 0.037
response to peptide GO:1901652 292 0.037
regulation of cell differentiation GO:0045595 320 0.036
catabolic process GO:0009056 351 0.036
cellular response to oxygen containing compound GO:1901701 386 0.036
response to inorganic substance GO:0010035 377 0.036
reproductive process GO:0022414 372 0.035
amine metabolic process GO:0009308 38 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.034
regulation of rna biosynthetic process GO:2001141 381 0.034
intracellular signal transduction GO:0035556 314 0.034
response to nutrient GO:0007584 248 0.033
regulation of nucleic acid templated transcription GO:1903506 380 0.033
regulation of molecular function GO:0065009 398 0.033
cellular component assembly GO:0022607 360 0.032
cellular amine metabolic process GO:0044106 38 0.032
organophosphate metabolic process GO:0019637 370 0.032
organic substance catabolic process GO:1901575 316 0.032
macromolecular complex assembly GO:0065003 273 0.032
single organism reproductive process GO:0044702 297 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.031
transcription dna templated GO:0006351 377 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
Mouse
neuron differentiation GO:0030182 368 0.031
transmembrane transport GO:0055085 412 0.031
negative regulation of metabolic process GO:0009892 331 0.031
Mouse
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.030
cellular component biogenesis GO:0044085 368 0.030
regulation of transcription dna templated GO:0006355 374 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
homeostatic process GO:0042592 331 0.030
regulation of cell development GO:0060284 263 0.030
cellular response to endogenous stimulus GO:0071495 377 0.030
positive regulation of biosynthetic process GO:0009891 319 0.030
regulation of signal transduction GO:0009966 318 0.030
protein complex assembly GO:0006461 263 0.029
regulation of cellular component organization GO:0051128 368 0.029
Mouse
cellular ketone metabolic process GO:0042180 51 0.029
nucleotide metabolic process GO:0009117 279 0.029
regulation of phosphate metabolic process GO:0019220 349 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
ion transmembrane transport GO:0034220 365 0.028
regulation of programmed cell death GO:0043067 341 0.028
positive regulation of developmental process GO:0051094 283 0.028
protein complex biogenesis GO:0070271 263 0.028
neuron development GO:0048666 286 0.028
protein complex subunit organization GO:0071822 302 0.028
regulation of protein metabolic process GO:0051246 289 0.028
regulation of neurogenesis GO:0050767 247 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
apoptotic process GO:0006915 381 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.026
head development GO:0060322 247 0.026
response to peptide hormone GO:0043434 278 0.026
regulation of catalytic activity GO:0050790 304 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
regulation of cell proliferation GO:0042127 359 0.026
purine containing compound metabolic process GO:0072521 253 0.026
response to molecule of bacterial origin GO:0002237 194 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
chemical homeostasis GO:0048878 292 0.026
central nervous system development GO:0007417 311 0.026
cellular homeostasis GO:0019725 252 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
regulation of nervous system development GO:0051960 264 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
regulation of phosphorylation GO:0042325 248 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
cation transport GO:0006812 382 0.025
single organism catabolic process GO:0044712 283 0.025
aging GO:0007568 241 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
positive regulation of rna metabolic process GO:0051254 203 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
protein oligomerization GO:0051259 191 0.024
regulation of neuron differentiation GO:0045664 208 0.024
cellular chemical homeostasis GO:0055082 247 0.024
cellular catabolic process GO:0044248 295 0.024
protein phosphorylation GO:0006468 345 0.024
response to acid chemical GO:0001101 222 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
Mouse
cell projection organization GO:0030030 302 0.024
reproduction GO:0000003 245 0.024
regulation of apoptotic process GO:0042981 335 0.024
multi organism reproductive process GO:0044703 262 0.023
cellular component movement GO:0006928 248 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
response to metal ion GO:0010038 253 0.023
metal ion transport GO:0030001 289 0.023
cellular response to stress GO:0033554 269 0.023
response to external biotic stimulus GO:0043207 221 0.023
negative regulation of gene expression GO:0010629 199 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
circulatory system process GO:0003013 183 0.022
response to biotic stimulus GO:0009607 226 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
secretion GO:0046903 307 0.022
neuron projection development GO:0031175 273 0.022
response to other organism GO:0051707 220 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
response to wounding GO:0009611 254 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
negative regulation of cell death GO:0060548 229 0.022
positive regulation of gene expression GO:0010628 244 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
response to corticosteroid GO:0031960 235 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
multicellular organism reproduction GO:0032504 233 0.021
positive regulation of cell development GO:0010720 176 0.021
cellular cation homeostasis GO:0030003 180 0.021
response to cytokine GO:0034097 215 0.021
ion homeostasis GO:0050801 212 0.021
regulation of protein modification process GO:0031399 194 0.021
locomotion GO:0040011 237 0.021
response to bacterium GO:0009617 200 0.021
brain development GO:0007420 247 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
single organism biosynthetic process GO:0044711 342 0.021
tissue development GO:0009888 252 0.021
Rat
cellular response to lipid GO:0071396 201 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
macromolecule localization GO:0033036 252 0.020
lipid metabolic process GO:0006629 283 0.020
response to estrogen GO:0043627 232 0.020
defense response GO:0006952 194 0.020
response to lipopolysaccharide GO:0032496 191 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
cell motility GO:0048870 202 0.020
cell migration GO:0016477 197 0.020
response to glucocorticoid GO:0051384 223 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
organelle organization GO:0006996 266 0.020
localization of cell GO:0051674 202 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
anion transport GO:0006820 178 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
cation homeostasis GO:0055080 195 0.019
nitrogen compound transport GO:0071705 229 0.019
blood circulation GO:0008015 183 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
positive regulation of molecular function GO:0044093 230 0.019
g protein coupled receptor signaling pathway GO:0007186 242 0.019
regulation of cellular localization GO:0060341 263 0.019
cellular ion homeostasis GO:0006873 184 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
response to decreased oxygen levels GO:0036293 237 0.019
positive regulation of nervous system development GO:0051962 178 0.019
negative regulation of apoptotic process GO:0043066 181 0.018
cell cell signaling GO:0007267 335 0.018
Mouse
regulation of system process GO:0044057 208 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
Rat
positive regulation of signaling GO:0023056 270 0.018
Mouse
positive regulation of cell communication GO:0010647 271 0.018
Mouse
metal ion homeostasis GO:0055065 186 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
response to ethanol GO:0045471 162 0.018
response to carbohydrate GO:0009743 183 0.018
immune system process GO:0002376 204 0.017
regulation of hormone levels GO:0010817 187 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
response to estradiol GO:0032355 164 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
response to growth factor GO:0070848 189 0.017
regulation of cell projection organization GO:0031344 175 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
positive regulation of cell death GO:0010942 184 0.017
nucleoside metabolic process GO:0009116 179 0.017
anterior posterior pattern specification GO:0009952 1 0.017
regulation of neuron projection development GO:0010975 161 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
heart morphogenesis GO:0003007 3 0.017
negative regulation of cell communication GO:0010648 158 0.017
regeneration GO:0031099 163 0.017
behavior GO:0007610 205 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
calcium ion homeostasis GO:0055074 162 0.016
nucleotide catabolic process GO:0009166 139 0.016
aromatic compound catabolic process GO:0019439 168 0.016
regulation of membrane potential GO:0042391 110 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
cellular lipid metabolic process GO:0044255 208 0.016
response to hypoxia GO:0001666 231 0.016
cation transmembrane transport GO:0098655 263 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
ras protein signal transduction GO:0007265 29 0.016
response to vitamin GO:0033273 131 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
response to ketone GO:1901654 182 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
gland development GO:0048732 155 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
positive regulation of signal transduction GO:0009967 175 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
response to oxygen levels GO:0070482 265 0.015
secretion by cell GO:0032940 248 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
synaptic transmission GO:0007268 235 0.015
Mouse
divalent inorganic cation homeostasis GO:0072507 165 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
divalent inorganic cation transport GO:0072511 134 0.015
response to purine containing compound GO:0014074 126 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
heterocycle catabolic process GO:0046700 167 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
peptidyl amino acid modification GO:0018193 126 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
response to monosaccharide GO:0034284 159 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
growth GO:0040007 165 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
response to camp GO:0051591 91 0.015
positive regulation of transport GO:0051050 245 0.015
positive regulation of protein modification process GO:0031401 142 0.015
negative regulation of transport GO:0051051 136 0.015
Mouse
single organism carbohydrate metabolic process GO:0044723 118 0.015
axis specification GO:0009798 4 0.014
multi multicellular organism process GO:0044706 138 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
proteolysis GO:0006508 175 0.014
carbohydrate metabolic process GO:0005975 130 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
intracellular transport GO:0046907 185 0.014
purine containing compound catabolic process GO:0072523 138 0.014
response to oxidative stress GO:0006979 186 0.014
inflammatory response GO:0006954 150 0.014
protein homooligomerization GO:0051260 91 0.014
regulation of secretion by cell GO:1903530 208 0.014
regulation of cell motility GO:2000145 131 0.014
response to glucose GO:0009749 136 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
single organism intracellular transport GO:1902582 166 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
response to hexose GO:0009746 144 0.014
organ regeneration GO:0031100 101 0.014
muscle system process GO:0003012 115 0.014
single organism organelle organization GO:1902589 180 0.014
developmental process involved in reproduction GO:0003006 159 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
sexual reproduction GO:0019953 148 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
organophosphate catabolic process GO:0046434 148 0.013
cellular component morphogenesis GO:0032989 155 0.013
organic anion transport GO:0015711 132 0.013
regulation of secretion GO:0051046 224 0.013
negative regulation of signaling GO:0023057 157 0.013
neurological system process GO:0050877 219 0.013
neuron death GO:0070997 127 0.013
regulation of cellular component movement GO:0051270 150 0.013
oxidation reduction process GO:0055114 304 0.013
regulation of hydrolase activity GO:0051336 143 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
tube development GO:0035295 89 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
protein transport GO:0015031 132 0.013
regulation of catabolic process GO:0009894 113 0.013
sex differentiation GO:0007548 113 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.012
cell type specific apoptotic process GO:0097285 134 0.012
response to toxic substance GO:0009636 133 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
divalent metal ion transport GO:0070838 132 0.012
cellular response to peptide GO:1901653 133 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
calcium ion transport GO:0006816 131 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
rhythmic process GO:0048511 156 0.012
gastrulation GO:0007369 2 0.012
cardiovascular system development GO:0072358 134 0.012
negative regulation of molecular function GO:0044092 133 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
response to insulin GO:0032868 133 0.012
amide transport GO:0042886 105 0.012
regulation of anatomical structure size GO:0090066 135 0.012
response to radiation GO:0009314 137 0.012
regulation of cell migration GO:0030334 128 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
cytoplasmic transport GO:0016482 115 0.012
regulation of mapk cascade GO:0043408 116 0.012
eye morphogenesis GO:0048592 4 0.012
regulation of locomotion GO:0040012 148 0.012
lipid storage GO:0019915 1 0.012
cell part morphogenesis GO:0032990 123 0.012
action potential GO:0001508 54 0.012
sulfur compound metabolic process GO:0006790 70 0.012
regulation of growth GO:0040008 105 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
regulation of ion transport GO:0043269 245 0.012
cellular response to external stimulus GO:0071496 118 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
regulation of transferase activity GO:0051338 123 0.012
response to reactive oxygen species GO:0000302 120 0.012
gamete generation GO:0007276 124 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
female pregnancy GO:0007565 122 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
mapk cascade GO:0000165 140 0.012
hormone transport GO:0009914 121 0.012
protein localization GO:0008104 191 0.011
circulatory system development GO:0072359 134 0.011
hexose metabolic process GO:0019318 58 0.011
gliogenesis GO:0042063 93 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
cell morphogenesis GO:0000902 142 0.011
negative regulation of innate immune response GO:0045824 4 0.011
regulation of immune system process GO:0002682 123 0.011
response to alkaloid GO:0043279 132 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
regulation of neuron death GO:1901214 115 0.011
monosaccharide metabolic process GO:0005996 61 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
embryonic pattern specification GO:0009880 1 0.011
hormone secretion GO:0046879 115 0.011
carboxylic acid transport GO:0046942 115 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
establishment of protein localization GO:0045184 141 0.011
cellular response to alcohol GO:0097306 87 0.011
small molecule biosynthetic process GO:0044283 124 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
response to organophosphorus GO:0046683 102 0.011
regulation of response to external stimulus GO:0032101 106 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
maintenance of location GO:0051235 17 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
reproductive system development GO:0061458 128 0.011
wound healing GO:0042060 122 0.011
muscle cell proliferation GO:0033002 84 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
chromosome segregation GO:0007059 2 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
organic acid transport GO:0015849 116 0.010
cell growth GO:0016049 104 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
hepaticobiliary system development GO:0061008 90 0.010
signal release GO:0023061 145 0.010
regulation of kinase activity GO:0043549 117 0.010
regulation of metal ion transport GO:0010959 118 0.010
rho protein signal transduction GO:0007266 11 0.010
reproductive structure development GO:0048608 128 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.010
anion transmembrane transport GO:0098656 77 0.010
peptide transport GO:0015833 97 0.010
smooth muscle cell proliferation GO:0048659 77 0.010
positive regulation of programmed cell death GO:0043068 157 0.010

Lrrtm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
disease of metabolism DOID:0014667 0 0.016
musculoskeletal system disease DOID:17 0 0.014
central nervous system disease DOID:331 0 0.013
sensory system disease DOID:0050155 0 0.013
eye disease DOID:5614 0 0.010
eye and adnexa disease DOID:1492 0 0.010
inherited metabolic disorder DOID:655 0 0.010