Rattus norvegicus

0 known processes

Ripk4

receptor-interacting serine-threonine kinase 4

Ripk4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.085
rna metabolic process GO:0016070 406 0.059
regulation of multicellular organismal development GO:2000026 376 0.056
single organism biosynthetic process GO:0044711 342 0.054
anion transport GO:0006820 178 0.054
regulation of cell differentiation GO:0045595 320 0.052
regulation of cell development GO:0060284 263 0.051
regulation of programmed cell death GO:0043067 341 0.050
Rat
regulation of cellular component organization GO:0051128 368 0.049
nucleic acid templated transcription GO:0097659 379 0.049
organic acid metabolic process GO:0006082 292 0.047
cellular response to oxygen containing compound GO:1901701 386 0.046
organophosphate metabolic process GO:0019637 370 0.046
regulation of cell proliferation GO:0042127 359 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.046
tissue development GO:0009888 252 0.043
regulation of nucleic acid templated transcription GO:1903506 380 0.043
amine metabolic process GO:0009308 38 0.043
gastrulation GO:0007369 2 0.041
positive regulation of developmental process GO:0051094 283 0.041
response to acid chemical GO:0001101 222 0.041
transmembrane transport GO:0055085 412 0.040
transcription dna templated GO:0006351 377 0.040
regulation of rna metabolic process GO:0051252 391 0.040
cellular ketone metabolic process GO:0042180 51 0.040
cation transport GO:0006812 382 0.040
protein localization GO:0008104 191 0.039
cellular amine metabolic process GO:0044106 38 0.038
oxoacid metabolic process GO:0043436 290 0.037
regulation of transcription dna templated GO:0006355 374 0.037
positive regulation of biosynthetic process GO:0009891 319 0.037
cellular response to endogenous stimulus GO:0071495 377 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
regulation of rna biosynthetic process GO:2001141 381 0.036
positive regulation of molecular function GO:0044093 230 0.036
regulation of secretion GO:0051046 224 0.035
action potential GO:0001508 54 0.035
positive regulation of gene expression GO:0010628 244 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.035
regulation of cellular amine metabolic process GO:0033238 8 0.034
regulation of neurogenesis GO:0050767 247 0.034
programmed cell death GO:0012501 392 0.033
Rat
defense response GO:0006952 194 0.033
cellular response to cytokine stimulus GO:0071345 127 0.033
central nervous system development GO:0007417 311 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.033
regulation of nervous system development GO:0051960 264 0.033
reproductive process GO:0022414 372 0.032
macromolecule localization GO:0033036 252 0.032
transcription from rna polymerase ii promoter GO:0006366 252 0.032
response to metal ion GO:0010038 253 0.032
intracellular signal transduction GO:0035556 314 0.032
regulation of system process GO:0044057 208 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.031
cell cell signaling GO:0007267 335 0.030
regulation of catalytic activity GO:0050790 304 0.030
regulation of membrane potential GO:0042391 110 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
cellular component movement GO:0006928 248 0.030
regulation of apoptotic process GO:0042981 335 0.030
inorganic cation transmembrane transport GO:0098662 202 0.029
rna biosynthetic process GO:0032774 380 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
cellular component biogenesis GO:0044085 368 0.028
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
response to cytokine GO:0034097 215 0.028
positive regulation of programmed cell death GO:0043068 157 0.028
Rat
neuron differentiation GO:0030182 368 0.028
regulation of signal transduction GO:0009966 318 0.028
regulation of molecular function GO:0065009 398 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
response to growth factor GO:0070848 189 0.027
response to inorganic substance GO:0010035 377 0.027
response to extracellular stimulus GO:0009991 380 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
metal ion transport GO:0030001 289 0.027
organic hydroxy compound metabolic process GO:1901615 115 0.027
regulation of cell projection organization GO:0031344 175 0.027
regulation of hormone levels GO:0010817 187 0.026
cellular component assembly GO:0022607 360 0.026
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
response to toxic substance GO:0009636 133 0.026
regulation of anatomical structure morphogenesis GO:0022603 141 0.026
ion transmembrane transport GO:0034220 365 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
biological adhesion GO:0022610 110 0.025
organic substance catabolic process GO:1901575 316 0.025
protein complex subunit organization GO:0071822 302 0.025
Rat
organelle organization GO:0006996 266 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
single organism catabolic process GO:0044712 283 0.024
organic anion transport GO:0015711 132 0.024
organ morphogenesis GO:0009887 75 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
positive regulation of cell development GO:0010720 176 0.024
secretion GO:0046903 307 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
Rat
negative regulation of developmental process GO:0051093 125 0.024
positive regulation of cell death GO:0010942 184 0.023
Rat
positive regulation of apoptotic process GO:0043065 154 0.023
nucleotide metabolic process GO:0009117 279 0.023
response to wounding GO:0009611 254 0.023
organic acid biosynthetic process GO:0016053 83 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
catabolic process GO:0009056 351 0.023
regulation of neuron projection development GO:0010975 161 0.023
regulation of neuron differentiation GO:0045664 208 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
negative regulation of metabolic process GO:0009892 331 0.023
response to external biotic stimulus GO:0043207 221 0.022
inorganic ion transmembrane transport GO:0098660 229 0.022
lipid metabolic process GO:0006629 283 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
oxidation reduction process GO:0055114 304 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
apoptotic process GO:0006915 381 0.021
secretion by cell GO:0032940 248 0.021
single organism organelle organization GO:1902589 180 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
organophosphate biosynthetic process GO:0090407 143 0.021
mesoderm development GO:0007498 2 0.021
cellular catabolic process GO:0044248 295 0.021
neurological system process GO:0050877 219 0.021
nitrogen compound transport GO:0071705 229 0.021
homeostatic process GO:0042592 331 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
tongue morphogenesis GO:0043587 3 0.021
blood circulation GO:0008015 183 0.021
multicellular organism growth GO:0035264 1 0.021
cellular lipid metabolic process GO:0044255 208 0.021
epithelium development GO:0060429 96 0.021
single organism reproductive process GO:0044702 297 0.021
proteolysis GO:0006508 175 0.021
lipid biosynthetic process GO:0008610 128 0.021
macromolecular complex assembly GO:0065003 273 0.021
Rat
positive regulation of transcription dna templated GO:0045893 197 0.020
chemical homeostasis GO:0048878 292 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
purine containing compound metabolic process GO:0072521 253 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
response to other organism GO:0051707 220 0.020
neuron death GO:0070997 127 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
fatty acid metabolic process GO:0006631 99 0.020
cell projection organization GO:0030030 302 0.019
response to peptide hormone GO:0043434 278 0.019
synaptic transmission GO:0007268 235 0.019
response to biotic stimulus GO:0009607 226 0.019
immune response GO:0006955 104 0.019
cellular response to lipid GO:0071396 201 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
protein phosphorylation GO:0006468 345 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
mapk cascade GO:0000165 140 0.019
response to peptide GO:1901652 292 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
inflammatory response GO:0006954 150 0.019
chromosome segregation GO:0007059 2 0.019
response to carbohydrate GO:0009743 183 0.018
regulation of cellular localization GO:0060341 263 0.018
heart morphogenesis GO:0003007 3 0.018
anatomical structure formation involved in morphogenesis GO:0048646 83 0.018
axis specification GO:0009798 4 0.018
circulatory system process GO:0003013 183 0.018
cation transmembrane transport GO:0098655 263 0.018
brain development GO:0007420 247 0.018
cell cycle GO:0007049 101 0.018
response to ketone GO:1901654 182 0.018
localization of cell GO:0051674 202 0.018
positive regulation of nervous system development GO:0051962 178 0.018
regulation of cellular component movement GO:0051270 150 0.018
head development GO:0060322 247 0.018
response to ethanol GO:0045471 162 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
regulation of ion transport GO:0043269 245 0.017
regulation of protein metabolic process GO:0051246 289 0.017
small molecule biosynthetic process GO:0044283 124 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
locomotion GO:0040011 237 0.017
metal ion homeostasis GO:0055065 186 0.017
cell motility GO:0048870 202 0.017
regulation of growth GO:0040008 105 0.017
reproduction GO:0000003 245 0.017
formation of primary germ layer GO:0001704 1 0.017
monovalent inorganic cation transport GO:0015672 172 0.017
negative regulation of cell differentiation GO:0045596 99 0.017
regulation of cell migration GO:0030334 128 0.017
response to estrogen GO:0043627 232 0.017
actin filament based process GO:0030029 86 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.016
regulation of secretion by cell GO:1903530 208 0.016
neuron development GO:0048666 286 0.016
regulation of phosphorylation GO:0042325 248 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
regulation of catabolic process GO:0009894 113 0.016
multicellular organismal signaling GO:0035637 44 0.016
organic acid transport GO:0015849 116 0.016
regulation of metal ion transport GO:0010959 118 0.016
response to nutrient levels GO:0031667 370 0.016
regulation of synaptic transmission GO:0050804 141 0.016
negative regulation of cell death GO:0060548 229 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
intestinal absorption GO:0050892 3 0.015
epithelial cell differentiation GO:0030855 71 0.015
immune system process GO:0002376 204 0.015
ras protein signal transduction GO:0007265 29 0.015
carboxylic acid transport GO:0046942 115 0.015
cellular homeostasis GO:0019725 252 0.015
negative regulation of cell communication GO:0010648 158 0.015
glycerolipid metabolic process GO:0046486 67 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
cardiac conduction GO:0061337 2 0.015
cellular response to stress GO:0033554 269 0.015
cell migration GO:0016477 197 0.015
cellular chemical homeostasis GO:0055082 247 0.015
positive regulation of protein modification process GO:0031401 142 0.015
organic hydroxy compound biosynthetic process GO:1901617 51 0.015
ion homeostasis GO:0050801 212 0.015
response to oxygen levels GO:0070482 265 0.015
multi organism reproductive process GO:0044703 262 0.015
glycosyl compound catabolic process GO:1901658 126 0.015
regulation of blood circulation GO:1903522 110 0.015
protein complex biogenesis GO:0070271 263 0.015
Rat
small gtpase mediated signal transduction GO:0007264 36 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
regulation of response to external stimulus GO:0032101 106 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
tube development GO:0035295 89 0.014
reproductive system development GO:0061458 128 0.014
anterior posterior pattern specification GO:0009952 1 0.014
cell growth GO:0016049 104 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
reproductive structure development GO:0048608 128 0.014
response to insulin GO:0032868 133 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
purine nucleoside catabolic process GO:0006152 124 0.014
response to decreased oxygen levels GO:0036293 237 0.014
growth GO:0040007 165 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
neuron projection development GO:0031175 273 0.014
terpenoid metabolic process GO:0006721 37 0.014
gliogenesis GO:0042063 93 0.014
dna metabolic process GO:0006259 96 0.014
transmission of nerve impulse GO:0019226 42 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
protein complex assembly GO:0006461 263 0.013
Rat
alcohol metabolic process GO:0006066 77 0.013
aging GO:0007568 241 0.013
circulatory system development GO:0072359 134 0.013
response to glucocorticoid GO:0051384 223 0.013
regulation of protein localization GO:0032880 81 0.013
multicellular organism reproduction GO:0032504 233 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
cytoskeleton organization GO:0007010 111 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
response to estradiol GO:0032355 164 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
regulation of dna metabolic process GO:0051052 60 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
response to lipopolysaccharide GO:0032496 191 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
carbohydrate metabolic process GO:0005975 130 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
intracellular transport GO:0046907 185 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
membrane organization GO:0061024 94 0.013
signal release GO:0023061 145 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
smooth muscle cell proliferation GO:0048659 77 0.013
positive regulation of cell communication GO:0010647 271 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
heterocycle catabolic process GO:0046700 167 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
lipid transport GO:0006869 61 0.013
negative regulation of signaling GO:0023057 157 0.013
positive regulation of signaling GO:0023056 270 0.013
sensory organ development GO:0007423 74 0.012
response to monosaccharide GO:0034284 159 0.012
digestive system development GO:0055123 41 0.012
female pregnancy GO:0007565 122 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
regeneration GO:0031099 163 0.012
response to ionizing radiation GO:0010212 59 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
purine containing compound catabolic process GO:0072523 138 0.012
response to glucose GO:0009749 136 0.012
positive regulation of catabolic process GO:0009896 78 0.012
cell type specific apoptotic process GO:0097285 134 0.012
protein oligomerization GO:0051259 191 0.012
Rat
meiotic cell cycle process GO:1903046 3 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
response to radiation GO:0009314 137 0.012
nucleoside metabolic process GO:0009116 179 0.012
acetate ester biosynthetic process GO:1900620 2 0.012
response to corticosteroid GO:0031960 235 0.012
positive regulation of mapk cascade GO:0043410 92 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
isoprenoid metabolic process GO:0006720 45 0.012
negative regulation of transport GO:0051051 136 0.012
cardiovascular system development GO:0072358 134 0.012
cellular hormone metabolic process GO:0034754 49 0.012
negative regulation of molecular function GO:0044092 133 0.012
regulation of cell growth GO:0001558 85 0.012
cell adhesion GO:0007155 110 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
cellular response to acid chemical GO:0071229 75 0.012
sodium ion transport GO:0006814 82 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
lipid storage GO:0019915 1 0.011
positive regulation of signal transduction GO:0009967 175 0.011
positive regulation of transport GO:0051050 245 0.011
cellular component morphogenesis GO:0032989 155 0.011
digestive tract development GO:0048565 39 0.011
olfactory behavior GO:0042048 2 0.011
regulation of hydrolase activity GO:0051336 143 0.011
circadian regulation of gene expression GO:0032922 3 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
response to hexose GO:0009746 144 0.011
muscle cell proliferation GO:0033002 84 0.011
peptide hormone secretion GO:0030072 84 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
response to bacterium GO:0009617 200 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
actin cytoskeleton organization GO:0030036 73 0.011
cellular cation homeostasis GO:0030003 180 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
neuronal action potential GO:0019228 35 0.011
hormone secretion GO:0046879 115 0.011
lipid localization GO:0010876 62 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
response to activity GO:0014823 73 0.011
cellular ion homeostasis GO:0006873 184 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
regulation of transferase activity GO:0051338 123 0.011
embryonic pattern specification GO:0009880 1 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
renal system development GO:0072001 67 0.011
phospholipid metabolic process GO:0006644 61 0.010
gland development GO:0048732 155 0.010
nucleotide catabolic process GO:0009166 139 0.010
developmental process involved in reproduction GO:0003006 159 0.010
coenzyme metabolic process GO:0006732 86 0.010
negative regulation of signal transduction GO:0009968 83 0.010
regulation of cell motility GO:2000145 131 0.010
wound healing GO:0042060 122 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
chemosensory behavior GO:0007635 2 0.010
cell cycle checkpoint GO:0000075 2 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
sensory perception GO:0007600 101 0.010
response to retinoic acid GO:0032526 63 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
positive regulation of stem cell differentiation GO:2000738 2 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
hormone metabolic process GO:0042445 69 0.010
cellular response to vitamin e GO:0071306 3 0.010
neuron apoptotic process GO:0051402 88 0.010
p38mapk cascade GO:0038066 1 0.010
response to vitamin GO:0033273 131 0.010
tube formation GO:0035148 3 0.010
morphogenesis of embryonic epithelium GO:0016331 3 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010

Ripk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.023
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
musculoskeletal system disease DOID:17 0 0.017
inherited metabolic disorder DOID:655 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
urinary system disease DOID:18 0 0.014
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011