Rattus norvegicus

30 known processes

Bcl10

B-cell CLL/lymphoma 10

Bcl10 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cell death GO:0060548 229 0.168
regulation of transcription dna templated GO:0006355 374 0.138
nucleic acid templated transcription GO:0097659 379 0.127
programmed cell death GO:0012501 392 0.127
positive regulation of cell communication GO:0010647 271 0.113
cellular response to oxygen containing compound GO:1901701 386 0.106
protein complex biogenesis GO:0070271 263 0.101
apoptotic process GO:0006915 381 0.100
positive regulation of response to stimulus GO:0048584 285 0.086
positive regulation of signaling GO:0023056 270 0.084
regulation of rna biosynthetic process GO:2001141 381 0.083
regulation of programmed cell death GO:0043067 341 0.080
regulation of phosphorylation GO:0042325 248 0.075
protein phosphorylation GO:0006468 345 0.074
transcription dna templated GO:0006351 377 0.074
immune system process GO:0002376 204 0.072
regulation of apoptotic process GO:0042981 335 0.071
positive regulation of signal transduction GO:0009967 175 0.067
rna metabolic process GO:0016070 406 0.064
protein heterooligomerization GO:0051291 89 0.063
regulation of signal transduction GO:0009966 318 0.062
rna biosynthetic process GO:0032774 380 0.061
regulation of intracellular signal transduction GO:1902531 218 0.059
negative regulation of apoptotic process GO:0043066 181 0.056
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.054
regulation of rna metabolic process GO:0051252 391 0.053
cellular response to stress GO:0033554 269 0.052
positive regulation of multicellular organismal process GO:0051240 387 0.051
intracellular signal transduction GO:0035556 314 0.051
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.051
mapk cascade GO:0000165 140 0.049
transmembrane transport GO:0055085 412 0.048
regulation of mapk cascade GO:0043408 116 0.047
cellular component assembly GO:0022607 360 0.046
response to hypoxia GO:0001666 231 0.046
response to decreased oxygen levels GO:0036293 237 0.046
regulation of nucleic acid templated transcription GO:1903506 380 0.044
positive regulation of cellular biosynthetic process GO:0031328 295 0.044
positive regulation of biosynthetic process GO:0009891 319 0.043
carboxylic acid metabolic process GO:0019752 289 0.043
cation transport GO:0006812 382 0.043
regulation of cellular amine metabolic process GO:0033238 8 0.042
response to acid chemical GO:0001101 222 0.041
transcription from rna polymerase ii promoter GO:0006366 252 0.041
reproductive process GO:0022414 372 0.041
negative regulation of transport GO:0051051 136 0.040
cellular response to endogenous stimulus GO:0071495 377 0.040
positive regulation of protein phosphorylation GO:0001934 135 0.040
regulation of ion transport GO:0043269 245 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
regulation of necroptotic process GO:0060544 2 0.039
negative regulation of programmed cell death GO:0043069 183 0.039
positive regulation of phosphate metabolic process GO:0045937 262 0.038
anterior posterior pattern specification GO:0009952 1 0.038
signal transduction by phosphorylation GO:0023014 144 0.038
regulation of protein metabolic process GO:0051246 289 0.037
regulation of cell differentiation GO:0045595 320 0.036
head development GO:0060322 247 0.036
embryonic pattern specification GO:0009880 1 0.036
nucleoside phosphate metabolic process GO:0006753 283 0.036
response to extracellular stimulus GO:0009991 380 0.036
positive regulation of cellular protein metabolic process GO:0032270 167 0.035
reactive oxygen species metabolic process GO:0072593 37 0.034
regulation of reactive oxygen species metabolic process GO:2000377 26 0.033
regulation of phosphorus metabolic process GO:0051174 349 0.033
regulation of cell proliferation GO:0042127 359 0.033
central nervous system development GO:0007417 311 0.033
regulation of molecular function GO:0065009 398 0.032
positive regulation of cell differentiation GO:0045597 217 0.031
regulation of multicellular organismal development GO:2000026 376 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
reactive nitrogen species metabolic process GO:2001057 1 0.030
protein complex subunit organization GO:0071822 302 0.030
negative regulation of signaling GO:0023057 157 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
reactive oxygen species biosynthetic process GO:1903409 8 0.030
positive regulation of phosphorylation GO:0042327 177 0.029
negative regulation of biosynthetic process GO:0009890 168 0.029
protein autophosphorylation GO:0046777 66 0.029
nitrogen compound transport GO:0071705 229 0.029
positive regulation of protein modification process GO:0031401 142 0.029
positive regulation of molecular function GO:0044093 230 0.029
response to cytokine GO:0034097 215 0.029
positive regulation of hydrolase activity GO:0051345 86 0.028
metal ion transport GO:0030001 289 0.028
cellular amine metabolic process GO:0044106 38 0.028
cell cycle checkpoint GO:0000075 2 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
ion transmembrane transport GO:0034220 365 0.027
negative regulation of cell communication GO:0010648 158 0.027
regulation of smooth muscle cell proliferation GO:0048660 75 0.027
cellular response to lipid GO:0071396 201 0.027
muscle cell proliferation GO:0033002 84 0.026
ras protein signal transduction GO:0007265 29 0.026
organic acid metabolic process GO:0006082 292 0.026
amine metabolic process GO:0009308 38 0.026
catabolic process GO:0009056 351 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
brain development GO:0007420 247 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
defense response GO:0006952 194 0.025
negative regulation of gene expression GO:0010629 199 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
cellular component biogenesis GO:0044085 368 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
positive regulation of intracellular signal transduction GO:1902533 138 0.024
necroptotic process GO:0070266 2 0.024
regulation of protein modification process GO:0031399 194 0.023
response to mechanical stimulus GO:0009612 134 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
peptidyl amino acid modification GO:0018193 126 0.023
negative regulation of metabolic process GO:0009892 331 0.023
g protein coupled receptor signaling pathway GO:0007186 242 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
nucleotide metabolic process GO:0009117 279 0.023
circulatory system process GO:0003013 183 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
positive regulation of rap gtpase activity GO:0032854 4 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.022
multicellular organism reproduction GO:0032504 233 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
response to oxygen levels GO:0070482 265 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
response to growth factor GO:0070848 189 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
reproduction GO:0000003 245 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
negative regulation of nucleic acid templated transcription GO:1903507 117 0.021
purine containing compound metabolic process GO:0072521 253 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
enzyme linked receptor protein signaling pathway GO:0007167 116 0.021
regulation of kinase activity GO:0043549 117 0.021
organic substance catabolic process GO:1901575 316 0.021
cell projection organization GO:0030030 302 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.020
positive regulation of mapk cascade GO:0043410 92 0.020
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.020
cellular ketone metabolic process GO:0042180 51 0.020
negative regulation of transcription dna templated GO:0045892 116 0.020
cardiovascular system development GO:0072358 134 0.020
regulation of synaptic transmission GO:0050804 141 0.020
multi organism reproductive process GO:0044703 262 0.020
embryonic axis specification GO:0000578 1 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
response to nutrient levels GO:0031667 370 0.019
regulation of cell development GO:0060284 263 0.019
epithelium development GO:0060429 96 0.019
protein oligomerization GO:0051259 191 0.019
muscle system process GO:0003012 115 0.019
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.019
response to inorganic substance GO:0010035 377 0.019
positive regulation of catalytic activity GO:0043085 184 0.018
cellular response to abiotic stimulus GO:0071214 85 0.018
cellular response to external stimulus GO:0071496 118 0.018
positive regulation of gene expression GO:0010628 244 0.018
cellular catabolic process GO:0044248 295 0.018
homeostatic process GO:0042592 331 0.018
regulation of system process GO:0044057 208 0.018
smooth muscle cell proliferation GO:0048659 77 0.018
response to interleukin 1 GO:0070555 55 0.018
response to wounding GO:0009611 254 0.018
regulation of transferase activity GO:0051338 123 0.018
biological adhesion GO:0022610 110 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
dendrite morphogenesis GO:0048813 43 0.018
vascular process in circulatory system GO:0003018 96 0.018
organophosphate metabolic process GO:0019637 370 0.018
regulation of protein kinase activity GO:0045859 105 0.018
cellular response to cytokine stimulus GO:0071345 127 0.017
organelle organization GO:0006996 266 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
cell morphogenesis GO:0000902 142 0.017
inorganic ion transmembrane transport GO:0098660 229 0.017
regulation of leukocyte activation GO:0002694 45 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
muscle contraction GO:0006936 88 0.017
axis specification GO:0009798 4 0.017
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.017
spermatogenesis GO:0007283 99 0.017
cytokine mediated signaling pathway GO:0019221 43 0.017
macromolecular complex assembly GO:0065003 273 0.017
regulation of cell motility GO:2000145 131 0.016
regulation of cell projection organization GO:0031344 175 0.016
protein complex assembly GO:0006461 263 0.016
carboxylic acid transport GO:0046942 115 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
regulation of response to stress GO:0080134 126 0.016
positive regulation of necrotic cell death GO:0010940 4 0.016
response to lipopolysaccharide GO:0032496 191 0.016
striated muscle contraction GO:0006941 44 0.016
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.016
neuron development GO:0048666 286 0.016
positive regulation of immune system process GO:0002684 90 0.016
ribonucleotide metabolic process GO:0009259 231 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
innate immune response GO:0045087 35 0.015
response to oxidative stress GO:0006979 186 0.015
lipid biosynthetic process GO:0008610 128 0.015
negative regulation of signal transduction GO:0009968 83 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
anion transport GO:0006820 178 0.015
calcium ion homeostasis GO:0055074 162 0.015
cellular chemical homeostasis GO:0055082 247 0.015
cell type specific apoptotic process GO:0097285 134 0.015
positive regulation of developmental process GO:0051094 283 0.015
synaptic transmission GO:0007268 235 0.015
chemical homeostasis GO:0048878 292 0.015
cellular ion homeostasis GO:0006873 184 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
single organism biosynthetic process GO:0044711 342 0.015
regulation of nervous system development GO:0051960 264 0.014
neuron projection development GO:0031175 273 0.014
regulation of nucleobase containing compound transport GO:0032239 1 0.014
blood circulation GO:0008015 183 0.014
neuron death GO:0070997 127 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
single organism behavior GO:0044708 130 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
positive regulation of nucleotide metabolic process GO:0045981 91 0.014
dendrite development GO:0016358 72 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.014
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.014
regulation of hormone secretion GO:0046883 106 0.014
regulation of embryonic development GO:0045995 2 0.014
regulation of peptide transport GO:0090087 87 0.014
macromolecule localization GO:0033036 252 0.013
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.013
regulation of secretion GO:0051046 224 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
neuron projection morphogenesis GO:0048812 122 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
response to radiation GO:0009314 137 0.013
divalent metal ion transport GO:0070838 132 0.013
regulation of transporter activity GO:0032409 50 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
cellular homeostasis GO:0019725 252 0.013
sexual reproduction GO:0019953 148 0.013
peptide transport GO:0015833 97 0.013
regulation of cellular component movement GO:0051270 150 0.013
cellular cation homeostasis GO:0030003 180 0.012
gastrulation GO:0007369 2 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
positive regulation of necroptotic process GO:0060545 2 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
positive regulation of cell development GO:0010720 176 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
membrane organization GO:0061024 94 0.012
neuron differentiation GO:0030182 368 0.012
regulation of hydrolase activity GO:0051336 143 0.012
proteolysis GO:0006508 175 0.012
peptidyl serine phosphorylation GO:0018105 33 0.012
cation transmembrane transport GO:0098655 263 0.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.012
cell migration GO:0016477 197 0.012
cellular response to mechanical stimulus GO:0071260 48 0.012
regulation of cellular localization GO:0060341 263 0.012
nuclear transport GO:0051169 49 0.012
dephosphorylation GO:0016311 98 0.012
ion homeostasis GO:0050801 212 0.012
macromolecule catabolic process GO:0009057 58 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
negative regulation of synaptic transmission GO:0050805 29 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
male gamete generation GO:0048232 99 0.012
positive regulation of kinase activity GO:0033674 77 0.011
cellular lipid metabolic process GO:0044255 208 0.011
oxoacid metabolic process GO:0043436 290 0.011
amide transport GO:0042886 105 0.011
cellular macromolecule catabolic process GO:0044265 29 0.011
cell growth GO:0016049 104 0.011
regulation of nucleoside metabolic process GO:0009118 66 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
substrate dependent cell migration GO:0006929 1 0.011
response to glucose GO:0009749 136 0.011
programmed necrotic cell death GO:0097300 2 0.011
embryo development GO:0009790 49 0.011
rho protein signal transduction GO:0007266 11 0.011
negative regulation of secretion GO:0051048 82 0.011
cell projection morphogenesis GO:0048858 123 0.011
regulation of ion transmembrane transporter activity GO:0032412 48 0.011
aromatic compound catabolic process GO:0019439 168 0.011
regulation of immune system process GO:0002682 123 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
neurotransmitter transport GO:0006836 42 0.011
peptide biosynthetic process GO:0043043 3 0.011
regulation of neurogenesis GO:0050767 247 0.011
regulation of transforming growth factor beta3 production GO:0032910 2 0.011
negative regulation of molecular function GO:0044092 133 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
hematopoietic or lymphoid organ development GO:0048534 36 0.010
regulation of anion transport GO:0044070 43 0.010
negative regulation of ion transport GO:0043271 51 0.010
response to corticosteroid GO:0031960 235 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 1 0.010
regulation of blood circulation GO:1903522 110 0.010
rna localization GO:0006403 4 0.010
heart development GO:0007507 72 0.010
macromolecular complex subunit organization GO:0043933 339 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
potassium ion transport GO:0006813 97 0.010
cellular response to acid chemical GO:0071229 75 0.010
response to ethanol GO:0045471 162 0.010
gamete generation GO:0007276 124 0.010
positive regulation of catabolic process GO:0009896 78 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
positive regulation of gtpase activity GO:0043547 47 0.010
glycosaminoglycan biosynthetic process GO:0006024 4 0.010
smad protein complex assembly GO:0007183 1 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.010
regulation of neuron differentiation GO:0045664 208 0.010
neurological system process GO:0050877 219 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
protein modification by small protein conjugation GO:0032446 31 0.010

Bcl10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.031
disease of cellular proliferation DOID:14566 0 0.031
organ system cancer DOID:0050686 0 0.031