Rattus norvegicus

50 known processes

Hfe

hemochromatosis

Hfe biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein localization GO:0008104 191 0.330
oxoacid metabolic process GO:0043436 290 0.295
positive regulation of signaling GO:0023056 270 0.269
regulation of phosphate metabolic process GO:0019220 349 0.236
organic acid metabolic process GO:0006082 292 0.227
regulation of molecular function GO:0065009 398 0.219
intracellular signal transduction GO:0035556 314 0.212
organonitrogen compound biosynthetic process GO:1901566 167 0.201
regulation of signal transduction GO:0009966 318 0.201
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.195
regulation of phosphorus metabolic process GO:0051174 349 0.189
gland development GO:0048732 155 0.182
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.175
chemical homeostasis GO:0048878 292 0.175
myeloid leukocyte differentiation GO:0002573 20 0.170
cellular amino acid metabolic process GO:0006520 107 0.155
anatomical structure morphogenesis GO:0009653 298 0.153
positive regulation of cell communication GO:0010647 271 0.152
carboxylic acid metabolic process GO:0019752 289 0.151
lipid metabolic process GO:0006629 283 0.150
cellular response to peptide hormone stimulus GO:0071375 120 0.148
response to corticosteroid GO:0031960 235 0.146
amine metabolic process GO:0009308 38 0.146
negative regulation of programmed cell death GO:0043069 183 0.143
transcription dna templated GO:0006351 377 0.143
cellular catabolic process GO:0044248 295 0.140
positive regulation of developmental process GO:0051094 283 0.139
Rat
positive regulation of molecular function GO:0044093 230 0.132
programmed cell death GO:0012501 392 0.130
positive regulation of cellular biosynthetic process GO:0031328 295 0.130
cellular response to lipid GO:0071396 201 0.124
apoptotic process GO:0006915 381 0.122
cellular response to organic cyclic compound GO:0071407 202 0.119
cellular response to glucocorticoid stimulus GO:0071385 68 0.119
cellular response to corticosteroid stimulus GO:0071384 69 0.118
regulation of kinase activity GO:0043549 117 0.118
cellular response to endogenous stimulus GO:0071495 377 0.113
positive regulation of catalytic activity GO:0043085 184 0.110
positive regulation of cell differentiation GO:0045597 217 0.108
negative regulation of metabolic process GO:0009892 331 0.107
regulation of phosphorylation GO:0042325 248 0.105
response to cytokine GO:0034097 215 0.103
regulation of nucleic acid templated transcription GO:1903506 380 0.102
single organism biosynthetic process GO:0044711 342 0.101
protein transport GO:0015031 132 0.100
regulation of apoptotic process GO:0042981 335 0.098
protein phosphorylation GO:0006468 345 0.098
negative regulation of cell death GO:0060548 229 0.097
regulation of intracellular signal transduction GO:1902531 218 0.097
positive regulation of cellular protein metabolic process GO:0032270 167 0.096
organophosphate metabolic process GO:0019637 370 0.095
response to glucocorticoid GO:0051384 223 0.095
response to other organism GO:0051707 220 0.094
positive regulation of transport GO:0051050 245 0.094
sulfur compound metabolic process GO:0006790 70 0.092
folic acid containing compound metabolic process GO:0006760 10 0.092
regulation of multicellular organismal development GO:2000026 376 0.092
Rat
aging GO:0007568 241 0.089
cellular response to alcohol GO:0097306 87 0.089
regulation of rna metabolic process GO:0051252 391 0.089
negative regulation of cellular metabolic process GO:0031324 281 0.089
organic substance catabolic process GO:1901575 316 0.088
response to wounding GO:0009611 254 0.088
regulation of programmed cell death GO:0043067 341 0.088
positive regulation of response to stimulus GO:0048584 285 0.088
Rat
positive regulation of cellular component movement GO:0051272 102 0.087
positive regulation of multicellular organismal process GO:0051240 387 0.087
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.086
regulation of cellular component organization GO:0051128 368 0.085
response to acid chemical GO:0001101 222 0.085
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.085
cellular protein localization GO:0034613 122 0.084
positive regulation of nucleic acid templated transcription GO:1903508 197 0.083
regulation of rna biosynthetic process GO:2001141 381 0.083
establishment of protein localization GO:0045184 141 0.083
positive regulation of signal transduction GO:0009967 175 0.082
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.081
neuron development GO:0048666 286 0.080
monocarboxylic acid metabolic process GO:0032787 152 0.080
liver development GO:0001889 90 0.079
neuron projection development GO:0031175 273 0.079
defense response GO:0006952 194 0.078
regulation of transcription dna templated GO:0006355 374 0.078
positive regulation of cell proliferation GO:0008284 249 0.078
positive regulation of protein kinase activity GO:0045860 73 0.077
regulation of secretion GO:0051046 224 0.075
positive regulation of gene expression GO:0010628 244 0.075
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.074
central nervous system development GO:0007417 311 0.073
chlorinated hydrocarbon metabolic process GO:0042196 4 0.073
regulation of cellular amino acid metabolic process GO:0006521 2 0.073
regulation of cell development GO:0060284 263 0.071
positive regulation of biosynthetic process GO:0009891 319 0.071
neuron differentiation GO:0030182 368 0.070
cellular response to steroid hormone stimulus GO:0071383 93 0.070
negative regulation of transcription dna templated GO:0045892 116 0.070
catabolic process GO:0009056 351 0.070
regulation of cell proliferation GO:0042127 359 0.069
positive regulation of intracellular signal transduction GO:1902533 138 0.069
nucleobase containing small molecule metabolic process GO:0055086 316 0.068
negative regulation of biosynthetic process GO:0009890 168 0.068
rna biosynthetic process GO:0032774 380 0.068
response to metal ion GO:0010038 253 0.067
response to monosaccharide GO:0034284 159 0.066
cell projection organization GO:0030030 302 0.066
negative regulation of signaling GO:0023057 157 0.066
cellular amine metabolic process GO:0044106 38 0.066
response to peptide GO:1901652 292 0.065
macromolecule localization GO:0033036 252 0.065
regulation of anatomical structure morphogenesis GO:0022603 141 0.064
cell projection morphogenesis GO:0048858 123 0.064
positive regulation of locomotion GO:0040017 102 0.064
cell part morphogenesis GO:0032990 123 0.063
positive regulation of phosphorylation GO:0042327 177 0.062
negative regulation of rna metabolic process GO:0051253 123 0.062
positive regulation of cell motility GO:2000147 97 0.062
regulation of protein metabolic process GO:0051246 289 0.060
negative regulation of cellular biosynthetic process GO:0031327 161 0.059
regulation of catalytic activity GO:0050790 304 0.059
positive regulation of rna biosynthetic process GO:1902680 197 0.059
positive regulation of response to external stimulus GO:0032103 51 0.059
negative regulation of nucleic acid templated transcription GO:1903507 117 0.058
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.058
response to lipopolysaccharide GO:0032496 191 0.057
cellular ketone metabolic process GO:0042180 51 0.057
negative regulation of gene expression GO:0010629 199 0.057
cell chemotaxis GO:0060326 31 0.057
positive regulation of cellular amine metabolic process GO:0033240 3 0.056
organonitrogen compound catabolic process GO:1901565 179 0.054
secretion GO:0046903 307 0.053
negative regulation of macromolecule metabolic process GO:0010605 260 0.053
alcohol metabolic process GO:0006066 77 0.053
cellular lipid metabolic process GO:0044255 208 0.053
cellular response to stress GO:0033554 269 0.052
response to carbohydrate GO:0009743 183 0.052
nucleic acid templated transcription GO:0097659 379 0.051
small molecule biosynthetic process GO:0044283 124 0.051
positive regulation of neurogenesis GO:0050769 165 0.051
regulation of retinal cell programmed cell death GO:0046668 1 0.050
positive regulation of phosphate metabolic process GO:0045937 262 0.050
positive regulation of transferase activity GO:0051347 81 0.050
regulation of cell differentiation GO:0045595 320 0.050
reactive oxygen species metabolic process GO:0072593 37 0.050
response to peptide hormone GO:0043434 278 0.049
response to molecule of bacterial origin GO:0002237 194 0.049
tissue development GO:0009888 252 0.049
mesoderm development GO:0007498 2 0.049
naphthalene containing compound metabolic process GO:0090420 2 0.048
response to xenobiotic stimulus GO:0009410 23 0.048
positive regulation of mapk cascade GO:0043410 92 0.048
regulation of transferase activity GO:0051338 123 0.048
cellular response to external stimulus GO:0071496 118 0.048
negative regulation of apoptotic process GO:0043066 181 0.047
regulation of mapk cascade GO:0043408 116 0.047
carbohydrate metabolic process GO:0005975 130 0.047
regulation of protein kinase activity GO:0045859 105 0.047
regulation of behavior GO:0050795 61 0.046
cellular response to oxygen containing compound GO:1901701 386 0.046
digestive system development GO:0055123 41 0.046
carbohydrate derivative metabolic process GO:1901135 346 0.046
cell cell signaling GO:0007267 335 0.045
response to ethanol GO:0045471 162 0.044
positive regulation of protein metabolic process GO:0051247 178 0.044
organ morphogenesis GO:0009887 75 0.044
positive regulation of phosphorus metabolic process GO:0010562 262 0.044
forebrain development GO:0030900 98 0.043
organic hydroxy compound biosynthetic process GO:1901617 51 0.043
response to inorganic substance GO:0010035 377 0.043
single organism carbohydrate metabolic process GO:0044723 118 0.042
positive regulation of tolerance induction GO:0002645 1 0.042
Rat
secretion by cell GO:0032940 248 0.042
regulation of cell migration GO:0030334 128 0.041
metal ion homeostasis GO:0055065 186 0.041
protein secretion GO:0009306 34 0.041
regulation of nervous system development GO:0051960 264 0.041
positive regulation of secretion by cell GO:1903532 128 0.041
positive regulation of chemotaxis GO:0050921 23 0.041
response to glucose GO:0009749 136 0.041
signal transduction by phosphorylation GO:0023014 144 0.040
regulation of cell motility GO:2000145 131 0.040
neurological system process GO:0050877 219 0.040
cellular response to organonitrogen compound GO:0071417 197 0.040
positive regulation of rna metabolic process GO:0051254 203 0.039
response to oxidative stress GO:0006979 186 0.039
regulation of protein modification process GO:0031399 194 0.039
response to estrogen GO:0043627 232 0.038
response to nutrient levels GO:0031667 370 0.038
neuron projection morphogenesis GO:0048812 122 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.038
head development GO:0060322 247 0.037
negative regulation of rna biosynthetic process GO:1902679 118 0.037
cellular macromolecule localization GO:0070727 122 0.037
positive regulation of transcription dna templated GO:0045893 197 0.037
lymphoid progenitor cell differentiation GO:0002320 2 0.037
response to hexose GO:0009746 144 0.037
circulatory system development GO:0072359 134 0.037
regulation of cellular amine metabolic process GO:0033238 8 0.037
gastrulation GO:0007369 2 0.036
negative regulation of cell proliferation GO:0008285 119 0.036
rna metabolic process GO:0016070 406 0.036
gliogenesis GO:0042063 93 0.036
oxidation reduction process GO:0055114 304 0.035
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.035
regulation of protein transport GO:0051223 68 0.035
nucleotide metabolic process GO:0009117 279 0.035
regulation of neural precursor cell proliferation GO:2000177 16 0.035
brain development GO:0007420 247 0.035
cell morphogenesis GO:0000902 142 0.035
organelle organization GO:0006996 266 0.035
reproductive process GO:0022414 372 0.035
tetrahydrofolate metabolic process GO:0046653 9 0.035
regulation of cellular ketone metabolic process GO:0010565 27 0.034
positive regulation of cell development GO:0010720 176 0.034
cation homeostasis GO:0055080 195 0.034
inflammatory response GO:0006954 150 0.034
positive regulation of protein phosphorylation GO:0001934 135 0.033
small molecule catabolic process GO:0044282 59 0.033
positive regulation of kinase activity GO:0033674 77 0.033
hepaticobiliary system development GO:0061008 90 0.032
positive regulation of nervous system development GO:0051962 178 0.032
multicellular organismal signaling GO:0035637 44 0.032
response to bacterium GO:0009617 200 0.031
cellular response to xenobiotic stimulus GO:0071466 19 0.031
gamete generation GO:0007276 124 0.031
cellular modified amino acid metabolic process GO:0006575 61 0.031
diterpenoid metabolic process GO:0016101 33 0.031
purine containing compound metabolic process GO:0072521 253 0.031
g protein coupled receptor signaling pathway GO:0007186 242 0.031
regulation of protein localization GO:0032880 81 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.031
mapk cascade GO:0000165 140 0.030
positive regulation of programmed cell death GO:0043068 157 0.030
ribonucleotide metabolic process GO:0009259 231 0.030
regulation of establishment of protein localization GO:0070201 69 0.030
regulation of neuron projection development GO:0010975 161 0.030
multi organism reproductive process GO:0044703 262 0.030
regulation of system process GO:0044057 208 0.030
regulation of protein phosphorylation GO:0001932 183 0.030
purine nucleotide metabolic process GO:0006163 229 0.030
regulation of hydrolase activity GO:0051336 143 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.030
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.030
single organism catabolic process GO:0044712 283 0.029
cytoskeleton organization GO:0007010 111 0.029
homeostatic process GO:0042592 331 0.029
single organism cellular localization GO:1902580 102 0.029
positive regulation of cell death GO:0010942 184 0.029
metal ion transport GO:0030001 289 0.028
Human Mouse
purine ribonucleoside metabolic process GO:0046128 168 0.028
hexose metabolic process GO:0019318 58 0.028
response to estradiol GO:0032355 164 0.028
leukocyte activation GO:0045321 76 0.028
protein complex subunit organization GO:0071822 302 0.028
salivary gland development GO:0007431 3 0.028
response to vitamin GO:0033273 131 0.027
development of primary sexual characteristics GO:0045137 107 0.027
cell activation GO:0001775 97 0.027
axis specification GO:0009798 4 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
response to toxic substance GO:0009636 133 0.027
tube development GO:0035295 89 0.027
salivary gland morphogenesis GO:0007435 1 0.027
cellular component movement GO:0006928 248 0.027
digestive tract development GO:0048565 39 0.027
wound healing GO:0042060 122 0.026
response to nutrient GO:0007584 248 0.026
nuclear transport GO:0051169 49 0.026
positive regulation of immune system process GO:0002684 90 0.026
Rat
organic cyclic compound catabolic process GO:1901361 175 0.026
fatty acid metabolic process GO:0006631 99 0.026
cellular response to extracellular stimulus GO:0031668 73 0.026
regulation of metal ion transport GO:0010959 118 0.025
positive regulation of hydrolase activity GO:0051345 86 0.025
regulation of reactive oxygen species metabolic process GO:2000377 26 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.025
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.025
response to dexamethasone GO:0071548 49 0.025
positive regulation of cell migration GO:0030335 96 0.025
cell motility GO:0048870 202 0.024
cellular component morphogenesis GO:0032989 155 0.024
cellular response to peptide GO:1901653 133 0.024
taxis GO:0042330 67 0.024
behavioral response to ethanol GO:0048149 1 0.024
organophosphate biosynthetic process GO:0090407 143 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
cellular component biogenesis GO:0044085 368 0.024
nucleoside metabolic process GO:0009116 179 0.024
neuron death GO:0070997 127 0.024
cytoplasmic transport GO:0016482 115 0.023
cofactor metabolic process GO:0051186 95 0.023
response to extracellular stimulus GO:0009991 380 0.023
regulation of membrane potential GO:0042391 110 0.023
regulation of neuron differentiation GO:0045664 208 0.023
heart process GO:0003015 57 0.023
organic hydroxy compound metabolic process GO:1901615 115 0.023
carbohydrate biosynthetic process GO:0016051 42 0.023
response to ionizing radiation GO:0010212 59 0.023
response to amino acid GO:0043200 75 0.023
dna metabolic process GO:0006259 96 0.023
aromatic compound catabolic process GO:0019439 168 0.023
immune system development GO:0002520 41 0.023
Rat
negative regulation of signal transduction GO:0009968 83 0.023
ion homeostasis GO:0050801 212 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
regulation of smooth muscle cell proliferation GO:0048660 75 0.022
immune response GO:0006955 104 0.022
Rat
biological adhesion GO:0022610 110 0.022
muscle cell proliferation GO:0033002 84 0.022
intracellular protein transport GO:0006886 79 0.022
cell type specific apoptotic process GO:0097285 134 0.022
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 1 0.022
smooth muscle cell proliferation GO:0048659 77 0.022
glycerolipid metabolic process GO:0046486 67 0.022
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.021
monosaccharide metabolic process GO:0005996 61 0.021
positive regulation of neural precursor cell proliferation GO:2000179 10 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.021
embryonic placenta development GO:0001892 1 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
response to transforming growth factor beta GO:0071559 46 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
multicellular organism reproduction GO:0032504 233 0.021
astrocyte activation GO:0048143 4 0.021
chemosensory behavior GO:0007635 2 0.021
regulation of homeostatic process GO:0032844 101 0.021
response to growth factor GO:0070848 189 0.021
regulation of hormone secretion GO:0046883 106 0.021
leukocyte differentiation GO:0002521 30 0.020
positive regulation of cytokine production GO:0001819 42 0.020
response to transition metal nanoparticle GO:1990267 122 0.020
organ formation GO:0048645 3 0.020
response to insulin GO:0032868 133 0.020
terpenoid metabolic process GO:0006721 37 0.020
embryonic pattern specification GO:0009880 1 0.020
pancreatic stellate cell proliferation GO:0072343 2 0.020
regulation of cell projection organization GO:0031344 175 0.020
divalent metal ion transport GO:0070838 132 0.020
transmission of nerve impulse GO:0019226 42 0.020
neural crest cell development GO:0014032 2 0.020
regulation of secretion by cell GO:1903530 208 0.019
dephosphorylation GO:0016311 98 0.019
glucose homeostasis GO:0042593 75 0.019
growth GO:0040007 165 0.019
negative regulation of cell cycle g1 s phase transition GO:1902807 2 0.019
cell migration GO:0016477 197 0.019
nucleocytoplasmic transport GO:0006913 48 0.019
cellular chemical homeostasis GO:0055082 247 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
protein complex biogenesis GO:0070271 263 0.019
chemotaxis GO:0006935 66 0.019
positive regulation of map kinase activity GO:0043406 46 0.019
cytokine production GO:0001816 61 0.019
divalent inorganic cation transport GO:0072511 134 0.019
response to biotic stimulus GO:0009607 226 0.019
organic acid biosynthetic process GO:0016053 83 0.019
negative regulation of cell cycle phase transition GO:1901988 4 0.018
actin cytoskeleton organization GO:0030036 73 0.018
negative regulation of phosphate metabolic process GO:0045936 80 0.018
regulation of neurogenesis GO:0050767 247 0.018
t cell tolerance induction GO:0002517 3 0.018
Rat
regulation of chemotaxis GO:0050920 29 0.018
cellular ion homeostasis GO:0006873 184 0.017
reproduction GO:0000003 245 0.017
isoprenoid metabolic process GO:0006720 45 0.017
response to external biotic stimulus GO:0043207 221 0.017
carboxylic acid catabolic process GO:0046395 49 0.017
regulation of response to external stimulus GO:0032101 106 0.017
cellular biogenic amine metabolic process GO:0006576 30 0.017
second messenger mediated signaling GO:0019932 51 0.017
single organism organelle organization GO:1902589 180 0.017
regulation of cellular localization GO:0060341 263 0.017
axon development GO:0061564 96 0.017
cellular homeostasis GO:0019725 252 0.017
cellular component assembly GO:0022607 360 0.017
positive regulation of secretion GO:0051047 140 0.016
lipid catabolic process GO:0016042 46 0.016
developmental growth GO:0048589 100 0.016
t cell activation GO:0042110 29 0.016
fatty acid biosynthetic process GO:0006633 33 0.016
ethanolamine containing compound metabolic process GO:0042439 14 0.016
cellular response to ketone GO:1901655 51 0.016
intracellular transport GO:0046907 185 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
lipid localization GO:0010876 62 0.016
lipid biosynthetic process GO:0008610 128 0.016
single organism reproductive process GO:0044702 297 0.016
monocarboxylic acid catabolic process GO:0072329 28 0.016
glial cell development GO:0021782 19 0.016
carbohydrate homeostasis GO:0033500 75 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
negative regulation of phosphorus metabolic process GO:0010563 80 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
response to oxygen levels GO:0070482 265 0.016
response to mechanical stimulus GO:0009612 134 0.016
erk1 and erk2 cascade GO:0070371 48 0.016
heterocycle catabolic process GO:0046700 167 0.015
sensory organ development GO:0007423 74 0.015
organic acid catabolic process GO:0016054 49 0.015
negative regulation of molecular function GO:0044092 133 0.015
myeloid leukocyte activation GO:0002274 36 0.015
response to zinc ion GO:0010043 39 0.015
regeneration GO:0031099 163 0.015
naphthalene metabolic process GO:0018931 2 0.015
nucleoside triphosphate catabolic process GO:0009143 123 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
regulation of protein serine threonine kinase activity GO:0071900 64 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
mast cell migration GO:0097531 4 0.015
rhythmic process GO:0048511 156 0.015
cation transport GO:0006812 382 0.015
Human Mouse
positive regulation of cellular component organization GO:0051130 200 0.015
hormone transport GO:0009914 121 0.015
cell cell signaling involved in cell fate commitment GO:0045168 2 0.015
eye morphogenesis GO:0048592 4 0.015
protein targeting to nucleus GO:0044744 35 0.015
positive regulation of protein modification process GO:0031401 142 0.015
developmental induction GO:0031128 2 0.015
unsaturated fatty acid metabolic process GO:0033559 39 0.015
cellular response to glucose stimulus GO:0071333 65 0.015
renal system development GO:0072001 67 0.015
response to epidermal growth factor GO:0070849 18 0.015
camera type eye development GO:0043010 48 0.014
urogenital system development GO:0001655 78 0.014
reproductive structure development GO:0048608 128 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
anatomical structure formation involved in morphogenesis GO:0048646 83 0.014
negative regulation of innate immune response GO:0045824 4 0.014
Rat
regulation of glucose transport GO:0010827 18 0.014
response to reactive oxygen species GO:0000302 120 0.014
lipid oxidation GO:0034440 30 0.014
peptidyl amino acid modification GO:0018193 126 0.014
hexose transport GO:0008645 29 0.014
cardiovascular system development GO:0072358 134 0.014
single organism intracellular transport GO:1902582 166 0.014
regulation of response to stress GO:0080134 126 0.014
Rat
olfactory behavior GO:0042048 2 0.014
regulation of cytokine production GO:0001817 56 0.014
activation of protein kinase activity GO:0032147 47 0.014
coronary vasculature morphogenesis GO:0060977 3 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
calcium ion transport GO:0006816 131 0.014
astrocyte development GO:0014002 4 0.014
neuronal action potential GO:0019228 35 0.013
multicellular organism growth GO:0035264 1 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
multi multicellular organism process GO:0044706 138 0.013
purine nucleoside monophosphate metabolic process GO:0009126 84 0.013
positive regulation of ion transport GO:0043270 94 0.013
hormone secretion GO:0046879 115 0.013
cellular cation homeostasis GO:0030003 180 0.013
norepinephrine metabolic process GO:0042415 3 0.013
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.013
cerebral cortex cell migration GO:0021795 4 0.013
regulation of cell cycle GO:0051726 73 0.013
regulation of gluconeogenesis GO:0006111 4 0.013
coenzyme metabolic process GO:0006732 86 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
negative regulation of cell communication GO:0010648 158 0.013
organophosphate catabolic process GO:0046434 148 0.013
regulation of ion transport GO:0043269 245 0.013
cellular response to hexose stimulus GO:0071331 65 0.013
regulation of carbohydrate metabolic process GO:0006109 41 0.013
peptide secretion GO:0002790 86 0.013
blood vessel morphogenesis GO:0048514 58 0.013
pseudopodium organization GO:0031268 3 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
endocrine hormone secretion GO:0060986 21 0.012
protein targeting GO:0006605 61 0.012
immune system process GO:0002376 204 0.012
Rat
gland morphogenesis GO:0022612 12 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
olfactory learning GO:0008355 1 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
regulation of epithelial cell proliferation GO:0050678 49 0.012
macromolecular complex assembly GO:0065003 273 0.012
maintenance of location GO:0051235 17 0.012
male gamete generation GO:0048232 99 0.012
fatty acid derivative metabolic process GO:1901568 38 0.012
sympathetic nervous system development GO:0048485 1 0.012
hematopoietic or lymphoid organ development GO:0048534 36 0.012
regulation of cellular response to stress GO:0080135 49 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
ribonucleoside metabolic process GO:0009119 174 0.012

Hfe disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.032
cancer DOID:162 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
organ system cancer DOID:0050686 0 0.032
liver cancer DOID:3571 0 0.016
disease of anatomical entity DOID:7 0 0.013
Human
vascular disease DOID:178 0 0.013
cardiovascular system disease DOID:1287 0 0.013