Rattus norvegicus

0 known processes

Slc7a8

solute carrier family 7 (cationic amino acid transporter, y+ system), member 8

(Aliases: Lat4,Lat2)

Slc7a8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
catabolic process GO:0009056 351 0.075
regulation of multicellular organismal development GO:2000026 376 0.074
regulation of molecular function GO:0065009 398 0.066
vesicle mediated transport GO:0016192 181 0.065
cell projection organization GO:0030030 302 0.065
neuron differentiation GO:0030182 368 0.064
anatomical structure morphogenesis GO:0009653 298 0.063
organic substance catabolic process GO:1901575 316 0.060
cellular component biogenesis GO:0044085 368 0.057
regulation of cellular component organization GO:0051128 368 0.050
organelle organization GO:0006996 266 0.048
neuron development GO:0048666 286 0.047
transmembrane transport GO:0055085 412 0.046
Human Yeast Rat
regulation of nervous system development GO:0051960 264 0.046
cell cell signaling GO:0007267 335 0.046
regulation of cell development GO:0060284 263 0.045
carbohydrate derivative metabolic process GO:1901135 346 0.044
response to peptide GO:1901652 292 0.044
response to corticosteroid GO:0031960 235 0.044
positive regulation of transport GO:0051050 245 0.043
response to extracellular stimulus GO:0009991 380 0.043
neuron projection development GO:0031175 273 0.043
single organism catabolic process GO:0044712 283 0.043
protein complex assembly GO:0006461 263 0.040
response to nutrient levels GO:0031667 370 0.040
regulation of phosphate metabolic process GO:0019220 349 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
macromolecular complex subunit organization GO:0043933 339 0.039
reproductive process GO:0022414 372 0.038
cellular response to oxygen containing compound GO:1901701 386 0.037
protein complex subunit organization GO:0071822 302 0.037
organophosphate metabolic process GO:0019637 370 0.036
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
aromatic compound catabolic process GO:0019439 168 0.036
cellular catabolic process GO:0044248 295 0.036
regulation of neurogenesis GO:0050767 247 0.036
small gtpase mediated signal transduction GO:0007264 36 0.036
cellular response to stress GO:0033554 269 0.035
response to inorganic substance GO:0010035 377 0.035
nucleoside metabolic process GO:0009116 179 0.035
nucleoside phosphate metabolic process GO:0006753 283 0.034
cellular response to endogenous stimulus GO:0071495 377 0.034
regulation of catalytic activity GO:0050790 304 0.034
nucleotide metabolic process GO:0009117 279 0.033
response to carbohydrate GO:0009743 183 0.033
cellular homeostasis GO:0019725 252 0.033
organonitrogen compound catabolic process GO:1901565 179 0.033
cation transport GO:0006812 382 0.033
Human Yeast Fly
regulation of cell differentiation GO:0045595 320 0.033
regulation of neuron differentiation GO:0045664 208 0.032
nucleobase containing compound catabolic process GO:0034655 152 0.031
nitrogen compound transport GO:0071705 229 0.030
Human Yeast Rat Fly
regulation of cellular protein metabolic process GO:0032268 267 0.030
reproduction GO:0000003 245 0.030
response to glucocorticoid GO:0051384 223 0.030
glycosyl compound metabolic process GO:1901657 182 0.030
organic cyclic compound catabolic process GO:1901361 175 0.029
purine containing compound metabolic process GO:0072521 253 0.029
response to peptide hormone GO:0043434 278 0.029
organic acid metabolic process GO:0006082 292 0.029
ribonucleoside metabolic process GO:0009119 174 0.029
regulation of intracellular signal transduction GO:1902531 218 0.028
intracellular signal transduction GO:0035556 314 0.028
ribose phosphate metabolic process GO:0019693 235 0.028
regulation of signal transduction GO:0009966 318 0.028
secretion GO:0046903 307 0.028
purine ribonucleotide metabolic process GO:0009150 227 0.028
ion transmembrane transport GO:0034220 365 0.027
Human Yeast Rat
single organism reproductive process GO:0044702 297 0.027
aging GO:0007568 241 0.027
cellular component assembly GO:0022607 360 0.027
nucleoside phosphate catabolic process GO:1901292 140 0.027
response to wounding GO:0009611 254 0.027
response to metal ion GO:0010038 253 0.027
apoptotic process GO:0006915 381 0.027
regulation of protein modification process GO:0031399 194 0.027
oxoacid metabolic process GO:0043436 290 0.027
regulation of cellular localization GO:0060341 263 0.026
protein oligomerization GO:0051259 191 0.026
carboxylic acid metabolic process GO:0019752 289 0.026
macromolecule localization GO:0033036 252 0.026
organophosphate catabolic process GO:0046434 148 0.026
regulation of anatomical structure morphogenesis GO:0022603 141 0.026
regulation of secretion GO:0051046 224 0.026
heterocycle catabolic process GO:0046700 167 0.026
response to ketone GO:1901654 182 0.026
response to decreased oxygen levels GO:0036293 237 0.026
purine ribonucleoside metabolic process GO:0046128 168 0.026
positive regulation of molecular function GO:0044093 230 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
cellular amine metabolic process GO:0044106 38 0.025
chemical homeostasis GO:0048878 292 0.025
positive regulation of developmental process GO:0051094 283 0.025
cellular response to hormone stimulus GO:0032870 247 0.025
carbohydrate derivative catabolic process GO:1901136 147 0.025
ras protein signal transduction GO:0007265 29 0.025
central nervous system development GO:0007417 311 0.025
Rat
secretion by cell GO:0032940 248 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
nucleotide catabolic process GO:0009166 139 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
cellular chemical homeostasis GO:0055082 247 0.024
protein complex biogenesis GO:0070271 263 0.024
response to nutrient GO:0007584 248 0.024
protein phosphorylation GO:0006468 345 0.024
multicellular organismal reproductive process GO:0048609 233 0.023
purine nucleotide catabolic process GO:0006195 136 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
actin filament based process GO:0030029 86 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
response to oxygen levels GO:0070482 265 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
tissue development GO:0009888 252 0.023
Rat
ribonucleotide catabolic process GO:0009261 136 0.023
metal ion transport GO:0030001 289 0.023
protein localization GO:0008104 191 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
response to hexose GO:0009746 144 0.022
single organism intracellular transport GO:1902582 166 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
purine containing compound catabolic process GO:0072523 138 0.022
macromolecular complex assembly GO:0065003 273 0.022
mapk cascade GO:0000165 140 0.022
regulation of programmed cell death GO:0043067 341 0.022
single organism biosynthetic process GO:0044711 342 0.022
response to glucose GO:0009749 136 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
synaptic transmission GO:0007268 235 0.021
regulation of system process GO:0044057 208 0.021
regeneration GO:0031099 163 0.021
ribonucleoside triphosphate catabolic process GO:0009203 122 0.021
monovalent inorganic cation transport GO:0015672 172 0.021
defense response GO:0006952 194 0.021
Fly
negative regulation of cellular metabolic process GO:0031324 281 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
homeostatic process GO:0042592 331 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
multi organism reproductive process GO:0044703 262 0.021
positive regulation of gene expression GO:0010628 244 0.021
cellular nitrogen compound catabolic process GO:0044270 163 0.021
programmed cell death GO:0012501 392 0.021
regulation of neuron projection development GO:0010975 161 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
developmental process involved in reproduction GO:0003006 159 0.020
positive regulation of signaling GO:0023056 270 0.020
regulation of protein metabolic process GO:0051246 289 0.020
negative regulation of metabolic process GO:0009892 331 0.020
axon development GO:0061564 96 0.020
sexual reproduction GO:0019953 148 0.020
calcium ion homeostasis GO:0055074 162 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.020
regulation of hormone levels GO:0010817 187 0.020
response to cytokine GO:0034097 215 0.020
cellular ketone metabolic process GO:0042180 51 0.020
amine metabolic process GO:0009308 38 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
cation transmembrane transport GO:0098655 263 0.019
Human Yeast
ribonucleoside catabolic process GO:0042454 126 0.019
cellular component movement GO:0006928 248 0.019
reproductive system development GO:0061458 128 0.019
regulation of phosphorylation GO:0042325 248 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.019
regulation of catabolic process GO:0009894 113 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.018
circulatory system process GO:0003013 183 0.018
negative regulation of cell communication GO:0010648 158 0.018
negative regulation of cell death GO:0060548 229 0.018
rna biosynthetic process GO:0032774 380 0.018
purine nucleoside catabolic process GO:0006152 124 0.018
cardiovascular system development GO:0072358 134 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
response to estradiol GO:0032355 164 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
growth GO:0040007 165 0.018
intracellular transport GO:0046907 185 0.018
gland development GO:0048732 155 0.018
regulation of apoptotic process GO:0042981 335 0.018
regulation of response to stress GO:0080134 126 0.017
anatomical structure formation involved in morphogenesis GO:0048646 83 0.017
purine nucleoside triphosphate catabolic process GO:0009146 122 0.017
ion homeostasis GO:0050801 212 0.017
regulation of anatomical structure size GO:0090066 135 0.017
nucleoside triphosphate metabolic process GO:0009141 144 0.017
localization of cell GO:0051674 202 0.017
response to monosaccharide GO:0034284 159 0.017
multi multicellular organism process GO:0044706 138 0.017
response to oxidative stress GO:0006979 186 0.017
Rat
proteolysis GO:0006508 175 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
forebrain development GO:0030900 98 0.017
nucleic acid templated transcription GO:0097659 379 0.017
regulation of cell projection organization GO:0031344 175 0.017
response to estrogen GO:0043627 232 0.017
regulation of transcription dna templated GO:0006355 374 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
circulatory system development GO:0072359 134 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
gamete generation GO:0007276 124 0.016
rna metabolic process GO:0016070 406 0.016
enzyme linked receptor protein signaling pathway GO:0007167 116 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.016
cellular response to peptide GO:1901653 133 0.016
response to growth factor GO:0070848 189 0.016
cell growth GO:0016049 104 0.016
positive regulation of cell development GO:0010720 176 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
brain development GO:0007420 247 0.016
Rat
protein transport GO:0015031 132 0.016
insulin like growth factor receptor signaling pathway GO:0048009 3 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
glycosyl compound catabolic process GO:1901658 126 0.016
locomotion GO:0040011 237 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
regulation of membrane potential GO:0042391 110 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
cytoskeleton organization GO:0007010 111 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
wound healing GO:0042060 122 0.015
nucleoside catabolic process GO:0009164 126 0.015
cation homeostasis GO:0055080 195 0.015
lipid metabolic process GO:0006629 283 0.015
response to ethanol GO:0045471 162 0.015
neuronal action potential GO:0019228 35 0.015
regulation of rna metabolic process GO:0051252 391 0.015
positive regulation of cell communication GO:0010647 271 0.015
response to insulin GO:0032868 133 0.015
reproductive structure development GO:0048608 128 0.015
cellular component morphogenesis GO:0032989 155 0.015
negative regulation of signaling GO:0023057 157 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
blood circulation GO:0008015 183 0.015
anion transport GO:0006820 178 0.015
Human Yeast Rat Fly
negative regulation of programmed cell death GO:0043069 183 0.015
cellular ion homeostasis GO:0006873 184 0.015
gonad development GO:0008406 104 0.015
positive regulation of protein modification process GO:0031401 142 0.015
regulation of cellular component movement GO:0051270 150 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
hormone secretion GO:0046879 115 0.014
regulation of secretion by cell GO:1903530 208 0.014
multicellular organism reproduction GO:0032504 233 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
oxidation reduction process GO:0055114 304 0.014
cellular lipid metabolic process GO:0044255 208 0.014
branched chain amino acid transport GO:0015803 2 0.014
Fly
neurological system process GO:0050877 219 0.014
muscle system process GO:0003012 115 0.014
single organism organelle organization GO:1902589 180 0.014
sex differentiation GO:0007548 113 0.014
organic anion transport GO:0015711 132 0.014
Human Yeast Rat Fly
cellular response to peptide hormone stimulus GO:0071375 120 0.014
transcription dna templated GO:0006351 377 0.014
regulation of cell proliferation GO:0042127 359 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
positive regulation of secretion GO:0051047 140 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
positive regulation of cell death GO:0010942 184 0.014
b cell differentiation GO:0030183 2 0.014
head development GO:0060322 247 0.014
Rat
regulation of cellular catabolic process GO:0031329 101 0.014
hormone metabolic process GO:0042445 69 0.014
regulation of transferase activity GO:0051338 123 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
spermatogenesis GO:0007283 99 0.014
response to hypoxia GO:0001666 231 0.014
response to acid chemical GO:0001101 222 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
regulation of ion transport GO:0043269 245 0.013
dna metabolic process GO:0006259 96 0.013
response to external biotic stimulus GO:0043207 221 0.013
Fly
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
development of primary sexual characteristics GO:0045137 107 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
heart morphogenesis GO:0003007 3 0.013
regulation of blood circulation GO:1903522 110 0.013
signal release GO:0023061 145 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
regulation of body fluid levels GO:0050878 90 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
axis specification GO:0009798 4 0.013
cell morphogenesis GO:0000902 142 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
gliogenesis GO:0042063 93 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
cell motility GO:0048870 202 0.013
tube development GO:0035295 89 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
membrane organization GO:0061024 94 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
regulation of hormone secretion GO:0046883 106 0.013
positive regulation of ion transport GO:0043270 94 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
spindle organization GO:0007051 2 0.013
cellular cation homeostasis GO:0030003 180 0.012
eye morphogenesis GO:0048592 4 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
adult locomotory behavior GO:0008344 4 0.012
metal ion homeostasis GO:0055065 186 0.012
negative regulation of cell development GO:0010721 82 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
male sex differentiation GO:0046661 64 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
regulation of purine nucleotide catabolic process GO:0033121 65 0.012
gtp metabolic process GO:0046039 72 0.012
rho protein signal transduction GO:0007266 11 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
cellular macromolecule localization GO:0070727 122 0.012
small molecule biosynthetic process GO:0044283 124 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
cell type specific apoptotic process GO:0097285 134 0.012
cellular response to lipid GO:0071396 201 0.012
regulation of immunoglobulin production GO:0002637 4 0.012
gastrulation GO:0007369 2 0.012
transmission of nerve impulse GO:0019226 42 0.012
negative regulation of transport GO:0051051 136 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
cell differentiation involved in kidney development GO:0061005 4 0.012
regulation of protein localization GO:0032880 81 0.012
male gamete generation GO:0048232 99 0.011
amide transport GO:0042886 105 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
cell cycle GO:0007049 101 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
positive regulation of signal transduction GO:0009967 175 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
sodium ion transport GO:0006814 82 0.011
response to purine containing compound GO:0014074 126 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
neuron projection morphogenesis GO:0048812 122 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
regulation of protein kinase activity GO:0045859 105 0.011
regulation of organelle organization GO:0033043 80 0.011
response to camp GO:0051591 91 0.011
positive regulation of immunoglobulin production GO:0002639 4 0.011
cellular response to alcohol GO:0097306 87 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
carbohydrate metabolic process GO:0005975 130 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
multicellular organismal signaling GO:0035637 44 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
response to mechanical stimulus GO:0009612 134 0.011
macromolecule catabolic process GO:0009057 58 0.011
establishment of protein localization GO:0045184 141 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
p38mapk cascade GO:0038066 1 0.011
circadian rhythm GO:0007623 88 0.011
action potential GO:0001508 54 0.011
inflammatory response GO:0006954 150 0.011
calcium ion transport GO:0006816 131 0.011
regulation of kinase activity GO:0043549 117 0.010
negative regulation of gene expression GO:0010629 199 0.010
response to bacterium GO:0009617 200 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
response to activity GO:0014823 73 0.010
behavior GO:0007610 205 0.010
male gonad development GO:0008584 59 0.010
regulation of growth GO:0040008 105 0.010
heart development GO:0007507 72 0.010
lipid biosynthetic process GO:0008610 128 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010
regulation of synaptic transmission GO:0050804 141 0.010
response to organophosphorus GO:0046683 102 0.010
positive regulation of catabolic process GO:0009896 78 0.010
response to radiation GO:0009314 137 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
cytoskeleton dependent cytokinesis GO:0061640 2 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
negative regulation of molecular function GO:0044092 133 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010

Slc7a8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.015
urinary system disease DOID:18 0 0.012
sensory system disease DOID:0050155 0 0.011
inherited metabolic disorder DOID:655 0 0.010