Rattus norvegicus

0 known processes

LOC304903

similar to Pappalysin-2 precursor (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP-E)

LOC304903 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.338
ion transmembrane transport GO:0034220 365 0.140
response to cytokine GO:0034097 215 0.114
cell migration GO:0016477 197 0.096
response to acid chemical GO:0001101 222 0.096
reproductive process GO:0022414 372 0.093
response to inorganic substance GO:0010035 377 0.090
regulation of molecular function GO:0065009 398 0.087
muscle cell migration GO:0014812 36 0.087
blood circulation GO:0008015 183 0.080
nitrogen compound transport GO:0071705 229 0.078
regulation of apoptotic process GO:0042981 335 0.077
response to peptide GO:1901652 292 0.075
cellular response to lipid GO:0071396 201 0.070
positive regulation of multicellular organismal process GO:0051240 387 0.068
rna metabolic process GO:0016070 406 0.065
metal ion transport GO:0030001 289 0.065
regulation of response to stress GO:0080134 126 0.064
gland development GO:0048732 155 0.063
mapk cascade GO:0000165 140 0.062
response to nutrient levels GO:0031667 370 0.061
regulation of rna metabolic process GO:0051252 391 0.061
head development GO:0060322 247 0.060
wound healing GO:0042060 122 0.059
negative regulation of programmed cell death GO:0043069 183 0.059
aging GO:0007568 241 0.059
immune system process GO:0002376 204 0.058
locomotion GO:0040011 237 0.057
negative regulation of cellular metabolic process GO:0031324 281 0.055
apoptotic process GO:0006915 381 0.055
regulation of transcription dna templated GO:0006355 374 0.054
negative regulation of metabolic process GO:0009892 331 0.054
cellular response to oxygen containing compound GO:1901701 386 0.053
regulation of programmed cell death GO:0043067 341 0.053
sensory perception GO:0007600 101 0.053
nucleic acid templated transcription GO:0097659 379 0.052
regulation of catalytic activity GO:0050790 304 0.052
regulation of phosphate metabolic process GO:0019220 349 0.050
divalent inorganic cation transport GO:0072511 134 0.049
programmed cell death GO:0012501 392 0.048
rna biosynthetic process GO:0032774 380 0.048
response to estrogen GO:0043627 232 0.046
response to wounding GO:0009611 254 0.046
positive regulation of cell proliferation GO:0008284 249 0.044
circulatory system process GO:0003013 183 0.044
regulation of cytokine production GO:0001817 56 0.044
cellular response to steroid hormone stimulus GO:0071383 93 0.043
signal transduction by phosphorylation GO:0023014 144 0.043
transcription dna templated GO:0006351 377 0.043
central nervous system development GO:0007417 311 0.042
multi organism reproductive process GO:0044703 262 0.041
cell motility GO:0048870 202 0.041
cellular response to alcohol GO:0097306 87 0.040
brain development GO:0007420 247 0.040
neurological system process GO:0050877 219 0.039
regulation of system process GO:0044057 208 0.038
response to peptide hormone GO:0043434 278 0.038
positive regulation of response to stimulus GO:0048584 285 0.038
response to hypoxia GO:0001666 231 0.038
regulation of protein metabolic process GO:0051246 289 0.037
regulation of locomotion GO:0040012 148 0.037
positive regulation of developmental process GO:0051094 283 0.037
positive regulation of nucleic acid templated transcription GO:1903508 197 0.037
cellular response to cytokine stimulus GO:0071345 127 0.036
regulation of signal transduction GO:0009966 318 0.036
negative regulation of multicellular organismal process GO:0051241 203 0.036
regulation of mapk cascade GO:0043408 116 0.036
cellular chemical homeostasis GO:0055082 247 0.036
secretion GO:0046903 307 0.036
negative regulation of gene expression GO:0010629 199 0.035
regulation of nucleic acid templated transcription GO:1903506 380 0.035
negative regulation of cellular biosynthetic process GO:0031327 161 0.034
regulation of rna biosynthetic process GO:2001141 381 0.034
negative regulation of apoptotic process GO:0043066 181 0.033
macromolecular complex assembly GO:0065003 273 0.033
response to extracellular stimulus GO:0009991 380 0.033
regulation of phosphorylation GO:0042325 248 0.032
cellular response to endogenous stimulus GO:0071495 377 0.032
cellular response to abiotic stimulus GO:0071214 85 0.032
regulation of kinase activity GO:0043549 117 0.032
positive regulation of biosynthetic process GO:0009891 319 0.032
cytosolic calcium ion homeostasis GO:0051480 140 0.031
cation homeostasis GO:0055080 195 0.031
calcium ion homeostasis GO:0055074 162 0.031
cellular cation homeostasis GO:0030003 180 0.031
protein complex biogenesis GO:0070271 263 0.030
glutamate secretion GO:0014047 19 0.030
immune response GO:0006955 104 0.030
negative regulation of cell death GO:0060548 229 0.030
positive regulation of rna biosynthetic process GO:1902680 197 0.030
smooth muscle cell migration GO:0014909 36 0.030
regulation of cellular localization GO:0060341 263 0.030
regulation of secretion GO:0051046 224 0.029
positive regulation of protein phosphorylation GO:0001934 135 0.029
glutathione transport GO:0034635 2 0.029
divalent metal ion transport GO:0070838 132 0.029
response to cocaine GO:0042220 39 0.029
neuron development GO:0048666 286 0.029
protein homooligomerization GO:0051260 91 0.028
cellular divalent inorganic cation homeostasis GO:0072503 162 0.028
positive regulation of molecular function GO:0044093 230 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.028
calcium ion transport GO:0006816 131 0.028
regulation of protein kinase activity GO:0045859 105 0.028
regulation of smooth muscle cell migration GO:0014910 36 0.028
divalent inorganic cation homeostasis GO:0072507 165 0.027
response to insulin GO:0032868 133 0.027
vesicle mediated transport GO:0016192 181 0.027
tripeptide transport GO:0042939 2 0.027
epithelial cell migration GO:0010631 19 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
ameboidal type cell migration GO:0001667 26 0.027
regulation of multicellular organismal development GO:2000026 376 0.027
regulation of protein modification process GO:0031399 194 0.027
cellular component movement GO:0006928 248 0.027
protein phosphorylation GO:0006468 345 0.027
regulation of protein phosphorylation GO:0001932 183 0.027
regulation of cell motility GO:2000145 131 0.027
cytokine production GO:0001816 61 0.027
sexual reproduction GO:0019953 148 0.026
positive regulation of protein kinase activity GO:0045860 73 0.026
negative regulation of response to stimulus GO:0048585 155 0.026
reproduction GO:0000003 245 0.025
positive regulation of transcription dna templated GO:0045893 197 0.025
negative regulation of transcription dna templated GO:0045892 116 0.025
synaptic transmission GO:0007268 235 0.025
neuron differentiation GO:0030182 368 0.025
regulation of leukocyte activation GO:0002694 45 0.025
protein oligomerization GO:0051259 191 0.025
cation transport GO:0006812 382 0.025
regulation of defense response GO:0031347 68 0.024
regulation of cell activation GO:0050865 50 0.024
regulation of cytokine biosynthetic process GO:0042035 3 0.024
positive regulation of mapk cascade GO:0043410 92 0.023
cell projection organization GO:0030030 302 0.023
urinary bladder smooth muscle contraction GO:0014832 4 0.023
intracellular signal transduction GO:0035556 314 0.023
regulation of response to wounding GO:1903034 69 0.023
regulation of vasculature development GO:1901342 44 0.023
homeostatic process GO:0042592 331 0.023
renal system development GO:0072001 67 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.022
response to oxygen levels GO:0070482 265 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
protein complex assembly GO:0006461 263 0.022
cellular metal ion homeostasis GO:0006875 172 0.022
response to monosaccharide GO:0034284 159 0.022
single organism reproductive process GO:0044702 297 0.022
positive regulation of cellular component movement GO:0051272 102 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
epithelium migration GO:0090132 19 0.022
multicellular organism reproduction GO:0032504 233 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.022
response to estradiol GO:0032355 164 0.022
establishment of protein localization GO:0045184 141 0.021
neuron projection development GO:0031175 273 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
cellular homeostasis GO:0019725 252 0.021
single organism organelle organization GO:1902589 180 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
positive regulation of saliva secretion GO:0046878 3 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
carboxylic acid metabolic process GO:0019752 289 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
chemical homeostasis GO:0048878 292 0.020
choline transport GO:0015871 4 0.020
response to corticosteroid GO:0031960 235 0.020
multi multicellular organism process GO:0044706 138 0.019
regulation of anatomical structure size GO:0090066 135 0.019
negative regulation of rna metabolic process GO:0051253 123 0.019
response to metal ion GO:0010038 253 0.019
single organism biosynthetic process GO:0044711 342 0.019
leukocyte activation GO:0045321 76 0.019
female pregnancy GO:0007565 122 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
positive regulation of gene expression GO:0010628 244 0.019
positive regulation of transport GO:0051050 245 0.019
cell cell signaling GO:0007267 335 0.018
cytokine mediated signaling pathway GO:0019221 43 0.018
regulation of transferase activity GO:0051338 123 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
ion homeostasis GO:0050801 212 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
cation transmembrane transport GO:0098655 263 0.018
protein complex subunit organization GO:0071822 302 0.018
positive regulation of kinase activity GO:0033674 77 0.018
positive regulation of transferase activity GO:0051347 81 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
developmental process involved in reproduction GO:0003006 159 0.017
response to molecule of fungal origin GO:0002238 3 0.017
positive regulation of cell communication GO:0010647 271 0.017
single organism intracellular transport GO:1902582 166 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
forebrain development GO:0030900 98 0.017
positive regulation of serotonin secretion GO:0014064 1 0.017
regulation of immune system process GO:0002682 123 0.017
actin filament based process GO:0030029 86 0.017
cellular component biogenesis GO:0044085 368 0.017
positive regulation of leukocyte degranulation GO:0043302 4 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
metal ion homeostasis GO:0055065 186 0.017
negative regulation of neuron death GO:1901215 69 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
vasculature development GO:0001944 70 0.017
amino acid transport GO:0006865 70 0.016
localization of cell GO:0051674 202 0.016
positive regulation of signaling GO:0023056 270 0.016
positive regulation of immune system process GO:0002684 90 0.016
vascular process in circulatory system GO:0003018 96 0.016
angiogenesis GO:0001525 53 0.016
response to decreased oxygen levels GO:0036293 237 0.016
actin filament organization GO:0007015 42 0.016
cellular response to estradiol stimulus GO:0071392 16 0.016
cytoskeleton organization GO:0007010 111 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
hormone secretion GO:0046879 115 0.016
cellular response to stress GO:0033554 269 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
mononuclear cell proliferation GO:0032943 29 0.015
defense response GO:0006952 194 0.015
negative regulation of secretion by cell GO:1903531 72 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
regulation of cell development GO:0060284 263 0.015
negative regulation of cell communication GO:0010648 158 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.015
neuropeptide signaling pathway GO:0007218 29 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
micturition GO:0060073 4 0.015
negative regulation of defecation GO:2000293 1 0.014
response to ammonium ion GO:0060359 71 0.014
response to reactive oxygen species GO:0000302 120 0.014
regulation of ion transport GO:0043269 245 0.014
regulation of epithelial cell migration GO:0010632 17 0.014
reproductive system development GO:0061458 128 0.014
epithelial cell differentiation GO:0030855 71 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
inflammatory response GO:0006954 150 0.014
regulation of amino acid transport GO:0051955 25 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
action potential GO:0001508 54 0.014
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.014
cellular response to external stimulus GO:0071496 118 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
positive regulation of peptide secretion GO:0002793 52 0.014
negative regulation of molecular function GO:0044092 133 0.013
urogenital system development GO:0001655 78 0.013
negative regulation of signaling GO:0023057 157 0.013
cellular amine metabolic process GO:0044106 38 0.013
response to hexose GO:0009746 144 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
cellular component assembly GO:0022607 360 0.013
positive regulation of signal transduction GO:0009967 175 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
positive regulation of cytokine production GO:0001819 42 0.013
response to dexamethasone GO:0071548 49 0.013
regulation of body fluid levels GO:0050878 90 0.013
regulation of angiogenesis GO:0045765 39 0.013
amide transport GO:0042886 105 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
prostate gland epithelium morphogenesis GO:0060740 2 0.012
regulation of membrane potential GO:0042391 110 0.012
kidney development GO:0001822 67 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
regulation of hormone secretion GO:0046883 106 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
response to transforming growth factor beta GO:0071559 46 0.012
regulation of response to external stimulus GO:0032101 106 0.012
glutamate receptor signaling pathway GO:0007215 43 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.011
positive regulation of protein modification process GO:0031401 142 0.011
epithelium development GO:0060429 96 0.011
embryonic skeletal system morphogenesis GO:0048704 3 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of neurogenesis GO:0050767 247 0.011
sensory perception of bitter taste GO:0050913 4 0.011
response to activity GO:0014823 73 0.011
somatostatin receptor signaling pathway GO:0038169 4 0.011
embryonic cranial skeleton morphogenesis GO:0048701 2 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
response to alkaloid GO:0043279 132 0.011
lymphocyte proliferation GO:0046651 29 0.011
regulation of neuron death GO:1901214 115 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
cellular ion homeostasis GO:0006873 184 0.011
myeloid leukocyte differentiation GO:0002573 20 0.011
response to oxidative stress GO:0006979 186 0.011
positive regulation of cell activation GO:0050867 34 0.011
regulation of hydrolase activity GO:0051336 143 0.011
regulation of secretion by cell GO:1903530 208 0.011
regulation of anion transport GO:0044070 43 0.011
positive regulation of cell death GO:0010942 184 0.010
leukocyte proliferation GO:0070661 29 0.010
rhythmic process GO:0048511 156 0.010
response to biotic stimulus GO:0009607 226 0.010
oxoacid metabolic process GO:0043436 290 0.010
positive regulation of cell differentiation GO:0045597 217 0.010
regulation of neuron apoptotic process GO:0043523 83 0.010
response to glucose GO:0009749 136 0.010
gamete generation GO:0007276 124 0.010
cellular response to peptide GO:1901653 133 0.010
negative regulation of chronic inflammatory response GO:0002677 2 0.010
regulation of nervous system development GO:0051960 264 0.010
negative regulation of amine transport GO:0051953 24 0.010

LOC304903 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020