Rattus norvegicus

0 known processes

Traf4af1

TRAF4 associated factor 1

(Aliases: MGC94986,C15orf23)

Traf4af1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome condensation GO:0030261 3 0.763
meiosis i GO:0007127 2 0.548
sister chromatid segregation GO:0000819 1 0.453
chromosome segregation GO:0007059 2 0.377
cellular response to iron iii ion GO:0071283 3 0.366
meiotic cell cycle process GO:1903046 3 0.298
regulation of chromosome segregation GO:0051983 1 0.242
mitotic spindle organization GO:0007052 2 0.175
cell cycle g1 s phase transition GO:0044843 13 0.173
dna packaging GO:0006323 4 0.144
mitotic sister chromatid separation GO:0051306 1 0.143
ventricular cardiac muscle cell differentiation GO:0055012 2 0.142
positive regulation of cellular protein metabolic process GO:0032270 167 0.141
regulation of proteasomal protein catabolic process GO:0061136 4 0.138
microtubule anchoring GO:0034453 1 0.132
ventricular cardiac muscle cell development GO:0055015 2 0.129
protein complex assembly GO:0006461 263 0.121
histone serine phosphorylation GO:0035404 1 0.115
macromolecular complex assembly GO:0065003 273 0.114
spindle organization GO:0007051 2 0.110
cell cycle checkpoint GO:0000075 2 0.108
regulation of cardiac muscle tissue development GO:0055024 12 0.106
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.106
response to ddt GO:0046680 1 0.100
dna metabolic process GO:0006259 96 0.092
regulation of mrna 3 end processing GO:0031440 1 0.092
protein complex biogenesis GO:0070271 263 0.091
microtubule polymerization or depolymerization GO:0031109 13 0.090
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.085
regulation of cell proliferation GO:0042127 359 0.085
cardiac muscle cell proliferation GO:0060038 6 0.083
cellular component assembly GO:0022607 360 0.081
neuron projection development GO:0031175 273 0.079
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.079
chromosome organization GO:0051276 36 0.070
histone phosphorylation GO:0016572 6 0.068
cellular component biogenesis GO:0044085 368 0.067
developmental growth GO:0048589 100 0.065
macromolecular complex subunit organization GO:0043933 339 0.062
maintenance of location GO:0051235 17 0.058
protein phosphorylation GO:0006468 345 0.057
negative regulation of apoptotic process GO:0043066 181 0.057
regulation of cell differentiation GO:0045595 320 0.057
regulation of microtubule polymerization or depolymerization GO:0031110 12 0.056
positive regulation of multicellular organismal process GO:0051240 387 0.055
regulation of molecular function GO:0065009 398 0.055
multicellular organism reproduction GO:0032504 233 0.055
regulation of protein metabolic process GO:0051246 289 0.053
regulation of cardiac muscle tissue growth GO:0055021 12 0.053
regulation of multicellular organismal development GO:2000026 376 0.052
cardiac muscle cell development GO:0055013 16 0.051
protein complex subunit organization GO:0071822 302 0.050
organelle assembly GO:0070925 22 0.049
regulation of organelle organization GO:0033043 80 0.049
negative regulation of microtubule depolymerization GO:0007026 3 0.048
multicellular organismal reproductive process GO:0048609 233 0.048
positive regulation of cellular catabolic process GO:0031331 71 0.047
positive regulation of histone phosphorylation GO:0033129 3 0.047
negative regulation of cellular metabolic process GO:0031324 281 0.046
negative regulation of cell cycle phase transition GO:1901988 4 0.046
tissue development GO:0009888 252 0.045
regulation of heart growth GO:0060420 12 0.044
mitotic sister chromatid segregation GO:0000070 1 0.044
centrosome organization GO:0051297 1 0.042
regeneration GO:0031099 163 0.041
cytokinetic process GO:0032506 1 0.040
regulation of cellular protein metabolic process GO:0032268 267 0.039
cytoskeleton organization GO:0007010 111 0.039
negative regulation of cell death GO:0060548 229 0.038
positive regulation of developmental process GO:0051094 283 0.038
positive regulation of lipid catabolic process GO:0050996 4 0.037
cellular response to iron ion GO:0071281 5 0.037
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.036
regulation of mitotic sister chromatid segregation GO:0033047 1 0.035
negative regulation of protein metabolic process GO:0051248 114 0.034
neuron development GO:0048666 286 0.033
positive regulation of cell proliferation GO:0008284 249 0.033
proteasomal protein catabolic process GO:0010498 8 0.033
cellular catabolic process GO:0044248 295 0.033
maintenance of protein location GO:0045185 7 0.032
mitotic cell cycle phase transition GO:0044772 20 0.031
microtubule organizing center organization GO:0031023 1 0.031
response to estrogen GO:0043627 232 0.031
cytoskeleton dependent cytokinesis GO:0061640 2 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
regulation of mitotic sister chromatid separation GO:0010965 1 0.031
negative regulation of programmed cell death GO:0043069 183 0.031
single organism reproductive process GO:0044702 297 0.031
single organism organelle organization GO:1902589 180 0.030
striated muscle cell proliferation GO:0014855 9 0.030
regulation of protein modification process GO:0031399 194 0.030
regulation of transferase activity GO:0051338 123 0.030
microtubule cytoskeleton organization GO:0000226 25 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
growth GO:0040007 165 0.030
negative regulation of cellular protein metabolic process GO:0032269 106 0.030
sexual reproduction GO:0019953 148 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.029
regulation of cell maturation GO:1903429 3 0.029
rna metabolic process GO:0016070 406 0.028
regulation of programmed cell death GO:0043067 341 0.028
cellular response to stress GO:0033554 269 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
cell cell signaling GO:0007267 335 0.027
reproductive process GO:0022414 372 0.026
muscle cell differentiation GO:0042692 52 0.026
proteolysis GO:0006508 175 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
regulation of catalytic activity GO:0050790 304 0.026
chromosome localization GO:0050000 1 0.026
cellular macromolecule catabolic process GO:0044265 29 0.026
macromolecule catabolic process GO:0009057 58 0.025
catabolic process GO:0009056 351 0.025
anterior posterior pattern specification GO:0009952 1 0.025
multi organism reproductive process GO:0044703 262 0.025
cellular component movement GO:0006928 248 0.024
programmed cell death GO:0012501 392 0.024
regulation of protein phosphorylation GO:0001932 183 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
response to metal ion GO:0010038 253 0.024
chromatin organization GO:0006325 34 0.024
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.024
cell projection organization GO:0030030 302 0.024
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.024
maintenance of protein location in cell GO:0032507 7 0.024
positive regulation of mrna metabolic process GO:1903313 4 0.024
cell cycle phase transition GO:0044770 21 0.024
negative regulation of metabolic process GO:0009892 331 0.024
neuron differentiation GO:0030182 368 0.023
regulation of organ growth GO:0046620 13 0.023
cellular ketone metabolic process GO:0042180 51 0.023
negative regulation of microtubule polymerization or depolymerization GO:0031111 6 0.023
regulation of mitotic cell cycle phase transition GO:1901990 11 0.023
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.023
regulation of ubiquitin protein transferase activity GO:0051438 1 0.023
rna biosynthetic process GO:0032774 380 0.023
metaphase plate congression GO:0051310 1 0.023
response to toxic substance GO:0009636 133 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
regulation of cell projection organization GO:0031344 175 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
circulatory system development GO:0072359 134 0.022
cellular protein localization GO:0034613 122 0.022
response to oxygen levels GO:0070482 265 0.022
cell cycle process GO:0022402 57 0.022
regulation of phosphorylation GO:0042325 248 0.022
regulation of phosphate metabolic process GO:0019220 349 0.022
dna conformation change GO:0071103 10 0.022
regulation of catabolic process GO:0009894 113 0.022
cellular amine metabolic process GO:0044106 38 0.022
mitotic cell cycle checkpoint GO:0007093 1 0.022
transcription dna templated GO:0006351 377 0.022
centrosome cycle GO:0007098 1 0.022
amine metabolic process GO:0009308 38 0.021
response to nutrient levels GO:0031667 370 0.021
brain development GO:0007420 247 0.021
protein autophosphorylation GO:0046777 66 0.021
reproduction GO:0000003 245 0.021
negative regulation of rna biosynthetic process GO:1902679 118 0.021
dna integrity checkpoint GO:0031570 2 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
muscle cell proliferation GO:0033002 84 0.020
cardiac muscle tissue growth GO:0055017 20 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
response to acid chemical GO:0001101 222 0.020
negative regulation of protein phosphorylation GO:0001933 44 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
negative regulation of phosphate metabolic process GO:0045936 80 0.020
mitotic cell cycle GO:0000278 49 0.020
regulation of cellular component organization GO:0051128 368 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
regulation of cellular catabolic process GO:0031329 101 0.020
central nervous system development GO:0007417 311 0.020
positive regulation of biosynthetic process GO:0009891 319 0.019
cardiac cell development GO:0055006 16 0.019
organelle fission GO:0048285 25 0.019
peptidyl amino acid modification GO:0018193 126 0.019
establishment of organelle localization GO:0051656 37 0.019
cellular protein catabolic process GO:0044257 19 0.019
single organism catabolic process GO:0044712 283 0.019
regulation of neurogenesis GO:0050767 247 0.019
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 3 0.018
response to inorganic substance GO:0010035 377 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
single organism biosynthetic process GO:0044711 342 0.018
establishment of chromosome localization GO:0051303 1 0.018
response to insecticide GO:0017085 21 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
histone modification GO:0016570 30 0.018
gamete generation GO:0007276 124 0.018
regulation of cell development GO:0060284 263 0.018
organelle organization GO:0006996 266 0.018
head development GO:0060322 247 0.017
regulation of chromosome organization GO:0033044 9 0.017
negative regulation of molecular function GO:0044092 133 0.017
spermatogenesis GO:0007283 99 0.017
negative regulation of phosphorus metabolic process GO:0010563 80 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
negative regulation of cellular component organization GO:0051129 83 0.017
regulation of developmental growth GO:0048638 45 0.017
regulation of microtubule cytoskeleton organization GO:0070507 14 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
organic acid metabolic process GO:0006082 292 0.017
positive regulation of synaptic plasticity GO:0031915 3 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
regulation of rna metabolic process GO:0051252 391 0.017
regulation of dendrite development GO:0050773 59 0.017
organophosphate metabolic process GO:0019637 370 0.016
cell growth GO:0016049 104 0.016
developmental process involved in reproduction GO:0003006 159 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
negative regulation of cell communication GO:0010648 158 0.016
nucleic acid templated transcription GO:0097659 379 0.016
regulation of sister chromatid segregation GO:0033045 1 0.016
development of primary sexual characteristics GO:0045137 107 0.016
g1 s transition of mitotic cell cycle GO:0000082 12 0.016
regulation of apoptotic process GO:0042981 335 0.016
embryonic appendage morphogenesis GO:0035113 4 0.016
chromosome separation GO:0051304 1 0.016
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.016
response to hypoxia GO:0001666 231 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
heart growth GO:0060419 20 0.016
metaphase anaphase transition of cell cycle GO:0044784 1 0.016
male gamete generation GO:0048232 99 0.015
negative regulation of gene expression GO:0010629 199 0.015
neuronal stem cell maintenance GO:0097150 2 0.015
positive regulation of nervous system development GO:0051962 178 0.015
purine containing compound metabolic process GO:0072521 253 0.015
cardiac muscle tissue development GO:0048738 26 0.015
positive regulation of gene expression GO:0010628 244 0.015
regulation of rna biosynthetic process GO:2001141 381 0.015
organic substance catabolic process GO:1901575 316 0.015
positive regulation of cell development GO:0010720 176 0.015
ubiquitin dependent protein catabolic process GO:0006511 14 0.015
cellular response to fluid shear stress GO:0071498 4 0.015
meiotic chromosome segregation GO:0045132 1 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
cell cycle GO:0007049 101 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
positive regulation of triglyceride metabolic process GO:0090208 4 0.015
peptidyl serine phosphorylation GO:0018105 33 0.015
developmental maturation GO:0021700 25 0.014
regulation of muscle tissue development GO:1901861 25 0.014
cell cycle dna replication GO:0044786 1 0.014
axis specification GO:0009798 4 0.014
pyrimidine nucleobase metabolic process GO:0006206 8 0.014
cellular response to acid chemical GO:0071229 75 0.014
striated muscle cell development GO:0055002 26 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
gonad development GO:0008406 104 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
neuron projection morphogenesis GO:0048812 122 0.014
regulation of kinase activity GO:0043549 117 0.014
negative regulation of phosphorylation GO:0042326 57 0.014
actin crosslink formation GO:0051764 3 0.014
ras protein signal transduction GO:0007265 29 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
positive regulation of protein modification process GO:0031401 142 0.013
regulation of protein complex assembly GO:0043254 33 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
regulation of striated muscle tissue development GO:0016202 25 0.013
cardiovascular system development GO:0072358 134 0.013
oxoacid metabolic process GO:0043436 290 0.013
positive regulation of muscle organ development GO:0048636 13 0.013
negative regulation of transport GO:0051051 136 0.013
microtubule based process GO:0007017 36 0.013
negative regulation of chromosome organization GO:2001251 1 0.013
positive regulation of molecular function GO:0044093 230 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 7 0.013
regulation of nervous system development GO:0051960 264 0.013
organelle localization GO:0051640 55 0.013
muscle tissue development GO:0060537 58 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
regulation of chromatin binding GO:0035561 3 0.012
nucleoside metabolic process GO:0009116 179 0.012
aging GO:0007568 241 0.012
regulation of neuron projection development GO:0010975 161 0.012
dna replication GO:0006260 37 0.012
response to fatty acid GO:0070542 65 0.012
regulation of synaptic transmission GO:0050804 141 0.012
positive regulation of proteasomal protein catabolic process GO:1901800 3 0.012
positive regulation of growth GO:0045927 55 0.012
negative regulation of protein modification process GO:0031400 52 0.012
regulation of cellular localization GO:0060341 263 0.012
macromolecule localization GO:0033036 252 0.012
regulation of protein serine threonine kinase activity GO:0071900 64 0.012
heart development GO:0007507 72 0.012
vesicle mediated transport GO:0016192 181 0.012
positive regulation of cytoskeleton organization GO:0051495 26 0.012
regulation of cell cycle GO:0051726 73 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
regulation of neuron differentiation GO:0045664 208 0.012
nucleocytoplasmic transport GO:0006913 48 0.012
locomotion GO:0040011 237 0.012
nucleotide metabolic process GO:0009117 279 0.011
cellular protein complex assembly GO:0043623 44 0.011
single organism intracellular transport GO:1902582 166 0.011
tissue regeneration GO:0042246 36 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
regulation of protein kinase activity GO:0045859 105 0.011
protein localization to chromosome centromeric region GO:0071459 1 0.011
cellular response to lipid GO:0071396 201 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
peptidyl threonine modification GO:0018210 7 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
covalent chromatin modification GO:0016569 30 0.011
regulation of transcription dna templated GO:0006355 374 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
positive regulation of organelle organization GO:0010638 48 0.011
regulation of cytoskeleton organization GO:0051493 49 0.011
homeostatic process GO:0042592 331 0.011
single organism nuclear import GO:1902593 35 0.011
regulation of cellular component biogenesis GO:0044087 86 0.010
apoptotic process GO:0006915 381 0.010
negative regulation of cell division GO:0051782 1 0.010
protein localization GO:0008104 191 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
glycerolipid metabolic process GO:0046486 67 0.010
negative regulation of nuclear division GO:0051784 1 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
negative regulation of protein maturation GO:1903318 47 0.010
positive regulation of rna biosynthetic process GO:1902680 197 0.010
protein localization to microtubule cytoskeleton GO:0072698 1 0.010
carboxylic acid metabolic process GO:0019752 289 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
cellular response to biotic stimulus GO:0071216 59 0.010
modification dependent protein catabolic process GO:0019941 14 0.010
response to extracellular stimulus GO:0009991 380 0.010

Traf4af1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
colon carcinoma DOID:1520 0 0.016
large intestine cancer DOID:5672 0 0.016
colon cancer DOID:219 0 0.016
gastrointestinal system cancer DOID:3119 0 0.016
intestinal cancer DOID:10155 0 0.016
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
colorectal cancer DOID:9256 0 0.016