Rattus norvegicus

0 known processes

Spag6

sperm associated antigen 6

(Aliases: RGD1310892)

Spag6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.046
organic acid metabolic process GO:0006082 292 0.044
oxoacid metabolic process GO:0043436 290 0.041
response to inorganic substance GO:0010035 377 0.039
reproductive process GO:0022414 372 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
response to extracellular stimulus GO:0009991 380 0.036
transcription dna templated GO:0006351 377 0.036
nucleic acid templated transcription GO:0097659 379 0.035
rna metabolic process GO:0016070 406 0.035
regulation of molecular function GO:0065009 398 0.035
homeostatic process GO:0042592 331 0.035
cellular amino acid metabolic process GO:0006520 107 0.033
single organism biosynthetic process GO:0044711 342 0.033
regulation of rna biosynthetic process GO:2001141 381 0.032
regulation of cell differentiation GO:0045595 320 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.031
response to nutrient levels GO:0031667 370 0.031
single organism reproductive process GO:0044702 297 0.031
cellular component biogenesis GO:0044085 368 0.031
regulation of rna metabolic process GO:0051252 391 0.031
rna biosynthetic process GO:0032774 380 0.031
apoptotic process GO:0006915 381 0.030
intracellular signal transduction GO:0035556 314 0.030
negative regulation of metabolic process GO:0009892 331 0.030
cellular response to endogenous stimulus GO:0071495 377 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
cellular response to oxygen containing compound GO:1901701 386 0.030
regulation of transcription dna templated GO:0006355 374 0.030
regulation of multicellular organismal development GO:2000026 376 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
protein phosphorylation GO:0006468 345 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
regulation of cell proliferation GO:0042127 359 0.028
response to oxygen levels GO:0070482 265 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
response to metal ion GO:0010038 253 0.028
cellular ketone metabolic process GO:0042180 51 0.028
cellular component assembly GO:0022607 360 0.027
multi organism reproductive process GO:0044703 262 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
programmed cell death GO:0012501 392 0.027
central nervous system development GO:0007417 311 0.027
g protein coupled receptor signaling pathway GO:0007186 242 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.027
cellular amine metabolic process GO:0044106 38 0.027
protein complex assembly GO:0006461 263 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
regulation of protein metabolic process GO:0051246 289 0.026
regulation of catalytic activity GO:0050790 304 0.026
amine metabolic process GO:0009308 38 0.026
response to bacterium GO:0009617 200 0.026
neuron differentiation GO:0030182 368 0.026
response to peptide GO:1901652 292 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.025
chemical homeostasis GO:0048878 292 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
response to nutrient GO:0007584 248 0.025
positive regulation of developmental process GO:0051094 283 0.025
positive regulation of gene expression GO:0010628 244 0.025
response to peptide hormone GO:0043434 278 0.025
regulation of programmed cell death GO:0043067 341 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.024
response to estrogen GO:0043627 232 0.024
cell projection organization GO:0030030 302 0.024
organophosphate metabolic process GO:0019637 370 0.024
regulation of cellular component organization GO:0051128 368 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
response to external biotic stimulus GO:0043207 221 0.024
locomotion GO:0040011 237 0.024
secretion GO:0046903 307 0.024
cell cell signaling GO:0007267 335 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
protein complex subunit organization GO:0071822 302 0.023
cellular homeostasis GO:0019725 252 0.023
positive regulation of molecular function GO:0044093 230 0.023
response to glucocorticoid GO:0051384 223 0.023
regulation of cell development GO:0060284 263 0.023
transmembrane transport GO:0055085 412 0.023
cellular component movement GO:0006928 248 0.023
regulation of apoptotic process GO:0042981 335 0.023
catabolic process GO:0009056 351 0.023
macromolecular complex assembly GO:0065003 273 0.023
cation transport GO:0006812 382 0.022
response to hypoxia GO:0001666 231 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
response to corticosteroid GO:0031960 235 0.022
regulation of nervous system development GO:0051960 264 0.022
regulation of neurogenesis GO:0050767 247 0.022
reproduction GO:0000003 245 0.022
response to cytokine GO:0034097 215 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
single organism catabolic process GO:0044712 283 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
head development GO:0060322 247 0.022
cellular chemical homeostasis GO:0055082 247 0.022
protein complex biogenesis GO:0070271 263 0.022
negative regulation of cell death GO:0060548 229 0.022
localization of cell GO:0051674 202 0.022
lipid metabolic process GO:0006629 283 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
response to decreased oxygen levels GO:0036293 237 0.021
brain development GO:0007420 247 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
aging GO:0007568 241 0.021
regulation of phosphorylation GO:0042325 248 0.021
response to growth factor GO:0070848 189 0.021
cellular response to stress GO:0033554 269 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
response to acid chemical GO:0001101 222 0.020
cellular response to lipid GO:0071396 201 0.020
metal ion transport GO:0030001 289 0.020
nucleotide metabolic process GO:0009117 279 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
response to molecule of bacterial origin GO:0002237 194 0.020
organic substance catabolic process GO:1901575 316 0.020
response to other organism GO:0051707 220 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
cell motility GO:0048870 202 0.020
secretion by cell GO:0032940 248 0.020
cell migration GO:0016477 197 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
positive regulation of signaling GO:0023056 270 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
ion homeostasis GO:0050801 212 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
purine containing compound metabolic process GO:0072521 253 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
multicellular organism reproduction GO:0032504 233 0.019
cellular lipid metabolic process GO:0044255 208 0.019
organelle organization GO:0006996 266 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
response to lipopolysaccharide GO:0032496 191 0.018
multi multicellular organism process GO:0044706 138 0.018
regulation of signal transduction GO:0009966 318 0.018
neuron development GO:0048666 286 0.018
immune system process GO:0002376 204 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
response to biotic stimulus GO:0009607 226 0.018
ion transmembrane transport GO:0034220 365 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
regulation of protein modification process GO:0031399 194 0.018
neuron projection development GO:0031175 273 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
blood circulation GO:0008015 183 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
protein oligomerization GO:0051259 191 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
cellular cation homeostasis GO:0030003 180 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
negative regulation of gene expression GO:0010629 199 0.018
defense response GO:0006952 194 0.018
circulatory system process GO:0003013 183 0.017
regulation of system process GO:0044057 208 0.017
synaptic transmission GO:0007268 235 0.017
intracellular transport GO:0046907 185 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
positive regulation of cell communication GO:0010647 271 0.017
cellular metal ion homeostasis GO:0006875 172 0.016
gland development GO:0048732 155 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
response to ketone GO:1901654 182 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
cellular ion homeostasis GO:0006873 184 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
cellular catabolic process GO:0044248 295 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
heart morphogenesis GO:0003007 3 0.016
positive regulation of transport GO:0051050 245 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
anterior posterior pattern specification GO:0009952 1 0.016
positive regulation of protein modification process GO:0031401 142 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
neurological system process GO:0050877 219 0.016
response to carbohydrate GO:0009743 183 0.016
regulation of cellular localization GO:0060341 263 0.016
inorganic ion transmembrane transport GO:0098660 229 0.015
axis specification GO:0009798 4 0.015
ras protein signal transduction GO:0007265 29 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
metal ion homeostasis GO:0055065 186 0.015
cation homeostasis GO:0055080 195 0.015
developmental process involved in reproduction GO:0003006 159 0.015
response to vitamin GO:0033273 131 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
response to ethanol GO:0045471 162 0.015
tissue development GO:0009888 252 0.015
sexual reproduction GO:0019953 148 0.015
regulation of cell projection organization GO:0031344 175 0.015
positive regulation of nervous system development GO:0051962 178 0.015
calcium ion homeostasis GO:0055074 162 0.015
negative regulation of cell communication GO:0010648 158 0.015
regeneration GO:0031099 163 0.015
regulation of secretion by cell GO:1903530 208 0.015
oxidation reduction process GO:0055114 304 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
negative regulation of developmental process GO:0051093 125 0.015
regulation of neuron differentiation GO:0045664 208 0.014
reproductive structure development GO:0048608 128 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
response to estradiol GO:0032355 164 0.014
cation transmembrane transport GO:0098655 263 0.014
growth GO:0040007 165 0.014
regulation of synaptic transmission GO:0050804 141 0.014
response to hexose GO:0009746 144 0.014
response to toxic substance GO:0009636 133 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
positive regulation of cell development GO:0010720 176 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
nucleoside metabolic process GO:0009116 179 0.014
response to amino acid GO:0043200 75 0.014
female pregnancy GO:0007565 122 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
single organism organelle organization GO:1902589 180 0.014
macromolecule localization GO:0033036 252 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
lipid biosynthetic process GO:0008610 128 0.014
regulation of locomotion GO:0040012 148 0.014
proteolysis GO:0006508 175 0.014
gastrulation GO:0007369 2 0.014
positive regulation of cell death GO:0010942 184 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
organonitrogen compound catabolic process GO:1901565 179 0.013
response to purine containing compound GO:0014074 126 0.013
regulation of anatomical structure size GO:0090066 135 0.013
response to wounding GO:0009611 254 0.013
regulation of neuron projection development GO:0010975 161 0.013
response to oxidative stress GO:0006979 186 0.013
single organism intracellular transport GO:1902582 166 0.013
negative regulation of signaling GO:0023057 157 0.013
organ regeneration GO:0031100 101 0.013
negative regulation of molecular function GO:0044092 133 0.013
gonad development GO:0008406 104 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
response to radiation GO:0009314 137 0.013
regulation of immune system process GO:0002682 123 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
regulation of hydrolase activity GO:0051336 143 0.013
cardiovascular system development GO:0072358 134 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
regulation of ion transport GO:0043269 245 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
carboxylic acid biosynthetic process GO:0046394 83 0.013
reproductive system development GO:0061458 128 0.013
organic acid biosynthetic process GO:0016053 83 0.013
cell part morphogenesis GO:0032990 123 0.013
rhythmic process GO:0048511 156 0.013
cellular response to peptide GO:1901653 133 0.013
regulation of membrane potential GO:0042391 110 0.013
small molecule biosynthetic process GO:0044283 124 0.013
bmp signaling pathway GO:0030509 4 0.012
regulation of hormone levels GO:0010817 187 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
response to monosaccharide GO:0034284 159 0.012
carbohydrate metabolic process GO:0005975 130 0.012
mapk cascade GO:0000165 140 0.012
response to reactive oxygen species GO:0000302 120 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
heterocycle catabolic process GO:0046700 167 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
limb morphogenesis GO:0035108 4 0.012
gamete generation GO:0007276 124 0.012
negative regulation of transport GO:0051051 136 0.012
regulation of catabolic process GO:0009894 113 0.012
cellular component morphogenesis GO:0032989 155 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
regulation of transferase activity GO:0051338 123 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
anion transport GO:0006820 178 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
regulation of secretion GO:0051046 224 0.012
divalent inorganic cation transport GO:0072511 134 0.012
cytoskeleton organization GO:0007010 111 0.012
protein localization GO:0008104 191 0.012
establishment of protein localization GO:0045184 141 0.012
nucleotide catabolic process GO:0009166 139 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
behavior GO:0007610 205 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
response to mechanical stimulus GO:0009612 134 0.012
response to glucose GO:0009749 136 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
cell activation GO:0001775 97 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
cellular response to alcohol GO:0097306 87 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
chromosome segregation GO:0007059 2 0.011
development of primary sexual characteristics GO:0045137 107 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
sex differentiation GO:0007548 113 0.011
positive regulation of cell motility GO:2000147 97 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
peptidyl amino acid modification GO:0018193 126 0.011
muscle system process GO:0003012 115 0.011
regulation of cellular component movement GO:0051270 150 0.011
regulation of metal ion transport GO:0010959 118 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
embryonic pattern specification GO:0009880 1 0.011
signal release GO:0023061 145 0.011
tube development GO:0035295 89 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
hepaticobiliary system development GO:0061008 90 0.011
circulatory system development GO:0072359 134 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
nitrogen compound transport GO:0071705 229 0.011
regulation of blood vessel size GO:0050880 89 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
embryonic skeletal system development GO:0048706 3 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
immune response GO:0006955 104 0.011
eye morphogenesis GO:0048592 4 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
lipid storage GO:0019915 1 0.011
appendage morphogenesis GO:0035107 4 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
cell morphogenesis GO:0000902 142 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
cellular response to external stimulus GO:0071496 118 0.010
response to organophosphorus GO:0046683 102 0.010
purine containing compound catabolic process GO:0072523 138 0.010
cell growth GO:0016049 104 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
response to camp GO:0051591 91 0.010
divalent metal ion transport GO:0070838 132 0.010
regulation of body fluid levels GO:0050878 90 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
regulation of mapk cascade GO:0043408 116 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
spermatogenesis GO:0007283 99 0.010
neuron death GO:0070997 127 0.010
calcium ion transport GO:0006816 131 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
aromatic compound catabolic process GO:0019439 168 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
positive regulation of signal transduction GO:0009967 175 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
regulation of homeostatic process GO:0032844 101 0.010
cytoplasmic transport GO:0016482 115 0.010
male gamete generation GO:0048232 99 0.010
negative regulation of innate immune response GO:0045824 4 0.010
protein homooligomerization GO:0051260 91 0.010
maintenance of location GO:0051235 17 0.010
protein transport GO:0015031 132 0.010
positive regulation of cellular component movement GO:0051272 102 0.010

Spag6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
sensory system disease DOID:0050155 0 0.014
musculoskeletal system disease DOID:17 0 0.013
eye and adnexa disease DOID:1492 0 0.013
disease of metabolism DOID:0014667 0 0.013
cardiovascular system disease DOID:1287 0 0.012
central nervous system disease DOID:331 0 0.012
eye disease DOID:5614 0 0.011
retinal disease DOID:5679 0 0.010