Rattus norvegicus

0 known processes

Gpc4

glypican 4

Gpc4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.074
oxoacid metabolic process GO:0043436 290 0.068
catabolic process GO:0009056 351 0.059
carboxylic acid metabolic process GO:0019752 289 0.052
rna metabolic process GO:0016070 406 0.051
rna biosynthetic process GO:0032774 380 0.051
regulation of transcription dna templated GO:0006355 374 0.051
regulation of signal transduction GO:0009966 318 0.049
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.048
ion transmembrane transport GO:0034220 365 0.047
response to extracellular stimulus GO:0009991 380 0.047
intracellular signal transduction GO:0035556 314 0.047
organic substance catabolic process GO:1901575 316 0.046
regulation of rna biosynthetic process GO:2001141 381 0.046
cellular amino acid metabolic process GO:0006520 107 0.045
nucleic acid templated transcription GO:0097659 379 0.043
regulation of nucleic acid templated transcription GO:1903506 380 0.042
regulation of intracellular signal transduction GO:1902531 218 0.041
regulation of catalytic activity GO:0050790 304 0.041
carbohydrate derivative metabolic process GO:1901135 346 0.039
positive regulation of phosphorus metabolic process GO:0010562 262 0.039
transcription dna templated GO:0006351 377 0.039
regulation of cell differentiation GO:0045595 320 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.038
regulation of rna metabolic process GO:0051252 391 0.038
regulation of molecular function GO:0065009 398 0.037
reproductive process GO:0022414 372 0.037
cellular catabolic process GO:0044248 295 0.037
regulation of multicellular organismal development GO:2000026 376 0.037
Rat
signal transduction by phosphorylation GO:0023014 144 0.036
single organism catabolic process GO:0044712 283 0.036
regulation of programmed cell death GO:0043067 341 0.036
cellular response to hormone stimulus GO:0032870 247 0.035
apoptotic process GO:0006915 381 0.035
neuron differentiation GO:0030182 368 0.035
Rat
cellular component biogenesis GO:0044085 368 0.035
central nervous system development GO:0007417 311 0.035
regulation of phosphate metabolic process GO:0019220 349 0.035
cellular component movement GO:0006928 248 0.034
positive regulation of phosphate metabolic process GO:0045937 262 0.034
single organism reproductive process GO:0044702 297 0.033
chemical homeostasis GO:0048878 292 0.033
negative regulation of signaling GO:0023057 157 0.033
Rat
neuron development GO:0048666 286 0.032
cellular response to endogenous stimulus GO:0071495 377 0.032
brain development GO:0007420 247 0.032
regulation of cellular protein metabolic process GO:0032268 267 0.032
cation transport GO:0006812 382 0.032
positive regulation of biosynthetic process GO:0009891 319 0.031
positive regulation of signal transduction GO:0009967 175 0.031
Rat
localization of cell GO:0051674 202 0.031
heart morphogenesis GO:0003007 3 0.031
cell migration GO:0016477 197 0.031
response to nutrient levels GO:0031667 370 0.030
programmed cell death GO:0012501 392 0.030
head development GO:0060322 247 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
organophosphate metabolic process GO:0019637 370 0.029
regulation of protein modification process GO:0031399 194 0.029
neuron projection development GO:0031175 273 0.029
cellular component assembly GO:0022607 360 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
protein complex biogenesis GO:0070271 263 0.029
positive regulation of developmental process GO:0051094 283 0.029
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
protein oligomerization GO:0051259 191 0.028
purine nucleoside metabolic process GO:0042278 169 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
cellular response to organic cyclic compound GO:0071407 202 0.028
single organism biosynthetic process GO:0044711 342 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.028
regulation of neuron projection development GO:0010975 161 0.028
regulation of protein phosphorylation GO:0001932 183 0.028
regulation of phosphorylation GO:0042325 248 0.027
regulation of apoptotic process GO:0042981 335 0.027
positive regulation of protein metabolic process GO:0051247 178 0.027
protein phosphorylation GO:0006468 345 0.027
positive regulation of signaling GO:0023056 270 0.027
Rat
response to oxygen levels GO:0070482 265 0.026
cellular response to lipid GO:0071396 201 0.026
regulation of neurogenesis GO:0050767 247 0.026
transmembrane transport GO:0055085 412 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
response to growth factor GO:0070848 189 0.026
organonitrogen compound catabolic process GO:1901565 179 0.025
cell motility GO:0048870 202 0.025
cellular response to oxygen containing compound GO:1901701 386 0.025
regulation of nervous system development GO:0051960 264 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
negative regulation of cell death GO:0060548 229 0.024
regeneration GO:0031099 163 0.024
regulation of cell projection organization GO:0031344 175 0.024
response to decreased oxygen levels GO:0036293 237 0.024
glycosyl compound metabolic process GO:1901657 182 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
purine containing compound metabolic process GO:0072521 253 0.023
response to hypoxia GO:0001666 231 0.023
locomotion GO:0040011 237 0.023
cation transmembrane transport GO:0098655 263 0.023
negative regulation of response to stimulus GO:0048585 155 0.023
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.023
carbohydrate metabolic process GO:0005975 130 0.023
anterior posterior pattern specification GO:0009952 1 0.023
positive regulation of cell differentiation GO:0045597 217 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
cell projection organization GO:0030030 302 0.022
ion homeostasis GO:0050801 212 0.022
positive regulation of protein modification process GO:0031401 142 0.022
response to peptide hormone GO:0043434 278 0.022
cell adhesion GO:0007155 110 0.022
cellular amine metabolic process GO:0044106 38 0.022
regulation of cell development GO:0060284 263 0.022
metal ion homeostasis GO:0055065 186 0.022
response to peptide GO:1901652 292 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
cellular chemical homeostasis GO:0055082 247 0.021
protein complex subunit organization GO:0071822 302 0.021
cellular cation homeostasis GO:0030003 180 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
Rat
ras protein signal transduction GO:0007265 29 0.021
homeostatic process GO:0042592 331 0.021
cardiovascular system development GO:0072358 134 0.020
cellular ketone metabolic process GO:0042180 51 0.020
positive regulation of gene expression GO:0010628 244 0.020
reproductive structure development GO:0048608 128 0.020
regulation of mapk cascade GO:0043408 116 0.020
enzyme linked receptor protein signaling pathway GO:0007167 116 0.020
regulation of membrane potential GO:0042391 110 0.020
axis specification GO:0009798 4 0.020
cellular ion homeostasis GO:0006873 184 0.020
gland development GO:0048732 155 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.020
amine metabolic process GO:0009308 38 0.020
alpha amino acid metabolic process GO:1901605 71 0.020
eye morphogenesis GO:0048592 4 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.020
gastrulation GO:0007369 2 0.020
multicellular organismal reproductive process GO:0048609 233 0.019
positive regulation of mapk cascade GO:0043410 92 0.019
secretion GO:0046903 307 0.019
regulation of cellular component organization GO:0051128 368 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
nitrogen compound transport GO:0071705 229 0.019
negative regulation of metabolic process GO:0009892 331 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
response to inorganic substance GO:0010035 377 0.019
cellular homeostasis GO:0019725 252 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
nucleotide metabolic process GO:0009117 279 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
regulation of ion transport GO:0043269 245 0.019
response to nutrient GO:0007584 248 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
blood circulation GO:0008015 183 0.018
response to glucocorticoid GO:0051384 223 0.018
multi organism reproductive process GO:0044703 262 0.018
regulation of neuron differentiation GO:0045664 208 0.018
cation homeostasis GO:0055080 195 0.018
positive regulation of cell communication GO:0010647 271 0.018
Rat
negative regulation of programmed cell death GO:0043069 183 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
regulation of transferase activity GO:0051338 123 0.018
cell cell signaling GO:0007267 335 0.018
aromatic compound catabolic process GO:0019439 168 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
biological adhesion GO:0022610 110 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
positive regulation of cell death GO:0010942 184 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
mapk cascade GO:0000165 140 0.017
response to metal ion GO:0010038 253 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
macromolecule localization GO:0033036 252 0.017
retina morphogenesis in camera type eye GO:0060042 1 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
urogenital system development GO:0001655 78 0.017
negative regulation of cell communication GO:0010648 158 0.017
Rat
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.017
cellular response to external stimulus GO:0071496 118 0.017
cardiac chamber development GO:0003205 1 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
negative regulation of signal transduction GO:0009968 83 0.016
Rat
response to estrogen GO:0043627 232 0.016
positive regulation of molecular function GO:0044093 230 0.016
response to acid chemical GO:0001101 222 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
multicellular organismal signaling GO:0035637 44 0.016
tissue development GO:0009888 252 0.016
regulation of kinase activity GO:0043549 117 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
organelle organization GO:0006996 266 0.016
mesoderm development GO:0007498 2 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
positive regulation of transferase activity GO:0051347 81 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
regulation of canonical wnt signaling pathway GO:0060828 4 0.016
Rat
protein complex assembly GO:0006461 263 0.016
regulation of cellular component movement GO:0051270 150 0.016
nucleoside metabolic process GO:0009116 179 0.016
growth GO:0040007 165 0.016
gonad development GO:0008406 104 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
embryonic pattern specification GO:0009880 1 0.016
circulatory system development GO:0072359 134 0.016
positive regulation of cell development GO:0010720 176 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
sex differentiation GO:0007548 113 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
negative regulation of cell proliferation GO:0008285 119 0.015
regulation of protein metabolic process GO:0051246 289 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
aging GO:0007568 241 0.015
response to corticosteroid GO:0031960 235 0.015
regulation of locomotion GO:0040012 148 0.015
organic anion transport GO:0015711 132 0.015
proteolysis GO:0006508 175 0.015
organ morphogenesis GO:0009887 75 0.015
action potential GO:0001508 54 0.015
heterocycle catabolic process GO:0046700 167 0.015
transmission of nerve impulse GO:0019226 42 0.015
anion transmembrane transport GO:0098656 77 0.014
macromolecular complex assembly GO:0065003 273 0.014
negative regulation of gene expression GO:0010629 199 0.014
bmp signaling pathway GO:0030509 4 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
cellular response to stress GO:0033554 269 0.014
gamete generation GO:0007276 124 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
purine containing compound catabolic process GO:0072523 138 0.014
developmental process involved in reproduction GO:0003006 159 0.014
response to glucose GO:0009749 136 0.014
response to hexose GO:0009746 144 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
secretion by cell GO:0032940 248 0.014
positive regulation of nervous system development GO:0051962 178 0.014
oxidation reduction process GO:0055114 304 0.014
multicellular organism reproduction GO:0032504 233 0.014
carboxylic acid transport GO:0046942 115 0.014
heart development GO:0007507 72 0.014
reproduction GO:0000003 245 0.014
regulation of cell proliferation GO:0042127 359 0.014
renal system development GO:0072001 67 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
amino acid transport GO:0006865 70 0.014
forebrain development GO:0030900 98 0.014
response to purine containing compound GO:0014074 126 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
reproductive system development GO:0061458 128 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
wound healing GO:0042060 122 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
multicellular organism growth GO:0035264 1 0.013
organophosphate catabolic process GO:0046434 148 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
protein localization GO:0008104 191 0.013
protein homooligomerization GO:0051260 91 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
camera type eye morphogenesis GO:0048593 2 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
circulatory system process GO:0003013 183 0.013
negative regulation of innate immune response GO:0045824 4 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
regulation of catabolic process GO:0009894 113 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
regulation of system process GO:0044057 208 0.013
cellular component morphogenesis GO:0032989 155 0.013
peptidyl amino acid modification GO:0018193 126 0.013
development of primary sexual characteristics GO:0045137 107 0.013
regulation of protein kinase activity GO:0045859 105 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
Rat
response to other organism GO:0051707 220 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
establishment of tissue polarity GO:0007164 2 0.012
neuronal action potential GO:0019228 35 0.012
cell morphogenesis GO:0000902 142 0.012
anion transport GO:0006820 178 0.012
negative regulation of developmental process GO:0051093 125 0.012
rhythmic process GO:0048511 156 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
neuron death GO:0070997 127 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
organic acid transport GO:0015849 116 0.012
response to carbohydrate GO:0009743 183 0.012
sexual reproduction GO:0019953 148 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
neurological system process GO:0050877 219 0.012
ossification GO:0001503 70 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
organ regeneration GO:0031100 101 0.012
muscle structure development GO:0061061 87 0.012
sulfur compound metabolic process GO:0006790 70 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
cofactor metabolic process GO:0051186 95 0.012
positive regulation of protein kinase activity GO:0045860 73 0.012
metal ion transport GO:0030001 289 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
calcium ion homeostasis GO:0055074 162 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
regulation of hydrolase activity GO:0051336 143 0.011
epithelial cell differentiation GO:0030855 71 0.011
regulation of cell growth GO:0001558 85 0.011
gliogenesis GO:0042063 93 0.011
lipid storage GO:0019915 1 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of blood circulation GO:1903522 110 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
regulation of cellular localization GO:0060341 263 0.011
actin filament based process GO:0030029 86 0.011
embryonic axis specification GO:0000578 1 0.011
neural crest cell migration GO:0001755 1 0.011
cell part morphogenesis GO:0032990 123 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
neuron projection morphogenesis GO:0048812 122 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
non canonical wnt signaling pathway GO:0035567 3 0.011
Rat
immune response GO:0006955 104 0.011
positive regulation of locomotion GO:0040017 102 0.011
adult locomotory behavior GO:0008344 4 0.011
cell growth GO:0016049 104 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
skeletal system development GO:0001501 41 0.011
regulation of mesenchymal cell proliferation GO:0010464 4 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
regulation of secretion GO:0051046 224 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
regulation of secretion by cell GO:1903530 208 0.010
regulation of response to stress GO:0080134 126 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
single organism organelle organization GO:1902589 180 0.010
response to starvation GO:0042594 59 0.010
morphogenesis of embryonic epithelium GO:0016331 3 0.010
morphogenesis of a polarized epithelium GO:0001738 1 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
positive regulation of kinase activity GO:0033674 77 0.010
response to alkaloid GO:0043279 132 0.010
macromolecule catabolic process GO:0009057 58 0.010
neural crest cell development GO:0014032 2 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
negative regulation of molecular function GO:0044092 133 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
regulation of dendrite development GO:0050773 59 0.010
epithelium development GO:0060429 96 0.010
response to bacterium GO:0009617 200 0.010
response to ketone GO:1901654 182 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
lipid metabolic process GO:0006629 283 0.010
coenzyme metabolic process GO:0006732 86 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
cellular modified amino acid metabolic process GO:0006575 61 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010
positive regulation of biomineral tissue development GO:0070169 4 0.010
response to vitamin GO:0033273 131 0.010
oligopeptide transport GO:0006857 4 0.010

Gpc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
musculoskeletal system disease DOID:17 0 0.028
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.021
sensory system disease DOID:0050155 0 0.015
connective tissue disease DOID:65 0 0.013
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
central nervous system disease DOID:331 0 0.012
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012