Rattus norvegicus

42 known processes

Nr1h3

nuclear receptor subfamily 1, group H, member 3

(Aliases: LXRalpha)

Nr1h3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 208 0.159
Human Mouse
response to extracellular stimulus GO:0009991 380 0.089
negative regulation of metabolic process GO:0009892 331 0.084
Mouse Rat
response to insulin GO:0032868 133 0.077
oxoacid metabolic process GO:0043436 290 0.071
Human
carboxylic acid metabolic process GO:0019752 289 0.066
Human
reproductive process GO:0022414 372 0.065
regulation of cellular protein metabolic process GO:0032268 267 0.064
Human Mouse
response to nutrient levels GO:0031667 370 0.058
chemical homeostasis GO:0048878 292 0.058
Human Mouse Worm
multi organism reproductive process GO:0044703 262 0.057
positive regulation of response to stimulus GO:0048584 285 0.054
Human
carbohydrate derivative metabolic process GO:1901135 346 0.053
response to peptide hormone GO:0043434 278 0.052
organic acid metabolic process GO:0006082 292 0.052
Human
regulation of cell proliferation GO:0042127 359 0.051
cellular amino acid metabolic process GO:0006520 107 0.050
lipid metabolic process GO:0006629 283 0.049
monocarboxylic acid metabolic process GO:0032787 152 0.049
Human
organic substance catabolic process GO:1901575 316 0.048
regulation of catalytic activity GO:0050790 304 0.046
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.046
Mouse Rat
response to glucocorticoid GO:0051384 223 0.046
regulation of transcription dna templated GO:0006355 374 0.046
Human Zebrafish Mouse Rat
response to peptide GO:1901652 292 0.046
regulation of molecular function GO:0065009 398 0.043
Human
negative regulation of molecular function GO:0044092 133 0.042
regulation of protein metabolic process GO:0051246 289 0.041
Human Mouse
regulation of phosphorylation GO:0042325 248 0.041
cellular hormone metabolic process GO:0034754 49 0.040
macromolecular complex assembly GO:0065003 273 0.039
negative regulation of cellular metabolic process GO:0031324 281 0.038
Mouse
programmed cell death GO:0012501 392 0.037
negative regulation of cellular protein metabolic process GO:0032269 106 0.037
Mouse
organic acid catabolic process GO:0016054 49 0.035
cation homeostasis GO:0055080 195 0.035
transmembrane transport GO:0055085 412 0.035
negative regulation of protein metabolic process GO:0051248 114 0.034
Mouse
regulation of phosphate metabolic process GO:0019220 349 0.033
positive regulation of cell proliferation GO:0008284 249 0.033
cellular ion homeostasis GO:0006873 184 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.030
Human Zebrafish Mouse Rat
cellular cation homeostasis GO:0030003 180 0.029
immune response GO:0006955 104 0.029
transcription dna templated GO:0006351 377 0.029
Human Zebrafish Mouse Rat
catabolic process GO:0009056 351 0.029
regulation of signal transduction GO:0009966 318 0.028
Human
macromolecule localization GO:0033036 252 0.027
Human Mouse Worm
carboxylic acid catabolic process GO:0046395 49 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
neurological system process GO:0050877 219 0.027
protein oligomerization GO:0051259 191 0.026
response to external biotic stimulus GO:0043207 221 0.026
Human Mouse
ion homeostasis GO:0050801 212 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
positive regulation of cell communication GO:0010647 271 0.026
Human
single organism catabolic process GO:0044712 283 0.026
metal ion homeostasis GO:0055065 186 0.026
oxidation reduction process GO:0055114 304 0.025
protein complex assembly GO:0006461 263 0.025
b cell differentiation GO:0030183 2 0.025
aging GO:0007568 241 0.025
regulation of hydrolase activity GO:0051336 143 0.025
Human
cellular component assembly GO:0022607 360 0.024
response to molecule of bacterial origin GO:0002237 194 0.024
Human Mouse
response to corticosteroid GO:0031960 235 0.024
cellular catabolic process GO:0044248 295 0.024
reproduction GO:0000003 245 0.024
Worm
protein complex biogenesis GO:0070271 263 0.024
cellular ketone metabolic process GO:0042180 51 0.024
Human
homeostatic process GO:0042592 331 0.023
Human Mouse Worm
regulation of hormone levels GO:0010817 187 0.023
cellular response to peptide hormone stimulus GO:0071375 120 0.023
response to nutrient GO:0007584 248 0.023
single organism reproductive process GO:0044702 297 0.022
cellular homeostasis GO:0019725 252 0.022
protein heterooligomerization GO:0051291 89 0.022
single organism biosynthetic process GO:0044711 342 0.022
Human
negative regulation of cell death GO:0060548 229 0.021
necroptotic process GO:0070266 2 0.021
organophosphate metabolic process GO:0019637 370 0.021
intracellular signal transduction GO:0035556 314 0.021
cellular amine metabolic process GO:0044106 38 0.021
regulation of programmed cell death GO:0043067 341 0.021
cellular component biogenesis GO:0044085 368 0.021
anion transport GO:0006820 178 0.020
protein phosphorylation GO:0006468 345 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
response to wounding GO:0009611 254 0.020
Mouse
aromatic compound catabolic process GO:0019439 168 0.020
cellular chemical homeostasis GO:0055082 247 0.020
cellular response to endogenous stimulus GO:0071495 377 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
Human Mouse Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
Human Mouse Rat
positive regulation of catalytic activity GO:0043085 184 0.019
Human
cellular calcium ion homeostasis GO:0006874 160 0.018
intestinal absorption GO:0050892 3 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
Mouse
central nervous system development GO:0007417 311 0.018
nitrogen compound transport GO:0071705 229 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
positive regulation of ion transport GO:0043270 94 0.018
organic acid biosynthetic process GO:0016053 83 0.018
Human
glycerolipid metabolic process GO:0046486 67 0.017
Human
apoptotic process GO:0006915 381 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
response to vitamin GO:0033273 131 0.017
cellular response to molecule of bacterial origin GO:0071219 56 0.016
Human Mouse
macromolecular complex subunit organization GO:0043933 339 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
Human Mouse Rat
developmental process involved in reproduction GO:0003006 159 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.015
nucleotide metabolic process GO:0009117 279 0.015
cellular response to metal ion GO:0071248 55 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
response to ethanol GO:0045471 162 0.015
response to glucose GO:0009749 136 0.015
regulation of rna biosynthetic process GO:2001141 381 0.015
Human Zebrafish Mouse Rat
secretion GO:0046903 307 0.015
Mouse
g protein coupled receptor signaling pathway GO:0007186 242 0.015
glycosyl compound metabolic process GO:1901657 182 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
Human
cell growth GO:0016049 104 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
cytoplasmic transport GO:0016482 115 0.014
protein complex subunit organization GO:0071822 302 0.014
positive regulation of transport GO:0051050 245 0.014
Human Mouse
negative regulation of apoptotic process GO:0043066 181 0.014
response to monosaccharide GO:0034284 159 0.014
sexual reproduction GO:0019953 148 0.014
carboxylic acid biosynthetic process GO:0046394 83 0.014
Human
lipid storage GO:0019915 1 0.014
Human Mouse Worm
metal ion transport GO:0030001 289 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
response to inorganic substance GO:0010035 377 0.014
spermatogenesis GO:0007283 99 0.014
amine metabolic process GO:0009308 38 0.014
negative regulation of transport GO:0051051 136 0.014
Human Mouse
cation transport GO:0006812 382 0.013
growth GO:0040007 165 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
Human Mouse Rat
regulation of neuron differentiation GO:0045664 208 0.013
regulation of cell differentiation GO:0045595 320 0.013
cellular response to corticosteroid stimulus GO:0071384 69 0.013
amide transport GO:0042886 105 0.013
multicellular organism growth GO:0035264 1 0.013
regulation of multicellular organismal development GO:2000026 376 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
regulation of cell development GO:0060284 263 0.013
negative regulation of gene expression GO:0010629 199 0.013
Mouse Rat
proteolysis GO:0006508 175 0.013
Mouse
gonad development GO:0008406 104 0.013
negative regulation of cell cycle phase transition GO:1901988 4 0.013
female pregnancy GO:0007565 122 0.013
secretion by cell GO:0032940 248 0.013
Mouse
ras protein signal transduction GO:0007265 29 0.013
negative regulation of innate immune response GO:0045824 4 0.013
regulation of protein modification process GO:0031399 194 0.012
cation transmembrane transport GO:0098655 263 0.012
response to oxygen levels GO:0070482 265 0.012
nucleic acid templated transcription GO:0097659 379 0.012
Human Zebrafish Mouse Rat
lipid localization GO:0010876 62 0.012
Human Mouse Worm
cellular response to external stimulus GO:0071496 118 0.012
chromosome segregation GO:0007059 2 0.012
regulation of cellular component organization GO:0051128 368 0.012
Human
regulation of vasculature development GO:1901342 44 0.012
immune system process GO:0002376 204 0.012
Human Mouse
heterocycle catabolic process GO:0046700 167 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
dephosphorylation GO:0016311 98 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
response to acid chemical GO:0001101 222 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
calcium ion homeostasis GO:0055074 162 0.012
positive regulation of developmental process GO:0051094 283 0.012
regulation of apoptotic process GO:0042981 335 0.012
alcohol metabolic process GO:0006066 77 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
multicellular organism reproduction GO:0032504 233 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.011
cell cell signaling GO:0007267 335 0.011
ion transmembrane transport GO:0034220 365 0.011
steroid metabolic process GO:0008202 73 0.011
maintenance of location GO:0051235 17 0.011
Human Mouse Worm
small gtpase mediated signal transduction GO:0007264 36 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
Human Zebrafish Mouse Rat
regeneration GO:0031099 163 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
protein localization GO:0008104 191 0.011
Mouse
organic hydroxy compound metabolic process GO:1901615 115 0.011
positive regulation of molecular function GO:0044093 230 0.011
Human
small molecule catabolic process GO:0044282 59 0.011
male gamete generation GO:0048232 99 0.011
cell killing GO:0001906 13 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
nucleoside metabolic process GO:0009116 179 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
rna metabolic process GO:0016070 406 0.011
Human Zebrafish Mouse Rat
nucleotide biosynthetic process GO:0009165 98 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
Human
protein maturation GO:0051604 68 0.011
Mouse
positive regulation of cell development GO:0010720 176 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
regulation of homeostatic process GO:0032844 101 0.011
Human Mouse
positive regulation of signal transduction GO:0009967 175 0.010
Human
protein processing GO:0016485 68 0.010
Mouse
organonitrogen compound catabolic process GO:1901565 179 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
response to toxic substance GO:0009636 133 0.010
gamete generation GO:0007276 124 0.010
reproductive structure development GO:0048608 128 0.010
cell cycle GO:0007049 101 0.010
acrosome assembly GO:0001675 3 0.010
response to carbohydrate GO:0009743 183 0.010
reproductive system development GO:0061458 128 0.010
regulation of cell cycle GO:0051726 73 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
Human
positive regulation of cellular amine metabolic process GO:0033240 3 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010

Nr1h3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.028
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
central nervous system disease DOID:331 0 0.012