Rattus norvegicus

37 known processes

H6pd

hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

H6pd biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.152
cellular amino acid metabolic process GO:0006520 107 0.089
regulation of nucleic acid templated transcription GO:1903506 380 0.074
transcription dna templated GO:0006351 377 0.071
regulation of rna biosynthetic process GO:2001141 381 0.070
nucleic acid templated transcription GO:0097659 379 0.064
carboxylic acid metabolic process GO:0019752 289 0.059
positive regulation of cellular biosynthetic process GO:0031328 295 0.059
positive regulation of biosynthetic process GO:0009891 319 0.057
regulation of molecular function GO:0065009 398 0.056
rna biosynthetic process GO:0032774 380 0.055
response to inorganic substance GO:0010035 377 0.052
organic acid metabolic process GO:0006082 292 0.051
transcription from rna polymerase ii promoter GO:0006366 252 0.051
secretion GO:0046903 307 0.050
response to metal ion GO:0010038 253 0.050
catabolic process GO:0009056 351 0.049
regulation of cell differentiation GO:0045595 320 0.048
positive regulation of phosphorus metabolic process GO:0010562 262 0.047
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.046
regulation of phosphorus metabolic process GO:0051174 349 0.046
regulation of transcription dna templated GO:0006355 374 0.045
rna metabolic process GO:0016070 406 0.045
organic substance catabolic process GO:1901575 316 0.044
response to nutrient levels GO:0031667 370 0.043
intracellular signal transduction GO:0035556 314 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.043
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.042
locomotion GO:0040011 237 0.041
regulation of rna metabolic process GO:0051252 391 0.041
small molecule biosynthetic process GO:0044283 124 0.040
cellular modified amino acid metabolic process GO:0006575 61 0.040
negative regulation of metabolic process GO:0009892 331 0.040
regulation of multicellular organismal development GO:2000026 376 0.040
chemical homeostasis GO:0048878 292 0.039
regulation of catalytic activity GO:0050790 304 0.039
cellular component assembly GO:0022607 360 0.039
response to wounding GO:0009611 254 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
positive regulation of rna biosynthetic process GO:1902680 197 0.038
regulation of phosphate metabolic process GO:0019220 349 0.038
response to peptide GO:1901652 292 0.038
regulation of cellular component organization GO:0051128 368 0.037
response to lipopolysaccharide GO:0032496 191 0.037
amine metabolic process GO:0009308 38 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.037
purine containing compound metabolic process GO:0072521 253 0.037
positive regulation of cell communication GO:0010647 271 0.036
macromolecular complex subunit organization GO:0043933 339 0.036
cell migration GO:0016477 197 0.036
multi organism reproductive process GO:0044703 262 0.036
negative regulation of gene expression GO:0010629 199 0.036
response to peptide hormone GO:0043434 278 0.035
positive regulation of cell differentiation GO:0045597 217 0.035
organelle organization GO:0006996 266 0.034
negative regulation of multicellular organismal process GO:0051241 203 0.034
cellular amino acid biosynthetic process GO:0008652 32 0.034
positive regulation of phosphate metabolic process GO:0045937 262 0.034
positive regulation of gene expression GO:0010628 244 0.034
positive regulation of response to stimulus GO:0048584 285 0.033
regulation of cell motility GO:2000145 131 0.033
localization of cell GO:0051674 202 0.033
neuron development GO:0048666 286 0.033
response to molecule of bacterial origin GO:0002237 194 0.033
positive regulation of cell proliferation GO:0008284 249 0.032
organophosphate metabolic process GO:0019637 370 0.032
positive regulation of signal transduction GO:0009967 175 0.032
transmembrane transport GO:0055085 412 0.032
cellular ketone metabolic process GO:0042180 51 0.031
positive regulation of developmental process GO:0051094 283 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
cell motility GO:0048870 202 0.030
cellular response to oxygen containing compound GO:1901701 386 0.030
macromolecule localization GO:0033036 252 0.030
positive regulation of signaling GO:0023056 270 0.030
response to external biotic stimulus GO:0043207 221 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
neuron differentiation GO:0030182 368 0.030
regulation of cellular ketone metabolic process GO:0010565 27 0.030
cellular response to endogenous stimulus GO:0071495 377 0.029
single organism catabolic process GO:0044712 283 0.029
cellular chemical homeostasis GO:0055082 247 0.029
regulation of cell migration GO:0030334 128 0.029
cellular component biogenesis GO:0044085 368 0.029
protein oligomerization GO:0051259 191 0.028
positive regulation of rna metabolic process GO:0051254 203 0.027
cellular amine metabolic process GO:0044106 38 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.027
ion homeostasis GO:0050801 212 0.027
multicellular organismal reproductive process GO:0048609 233 0.027
cellular component movement GO:0006928 248 0.027
epithelium development GO:0060429 96 0.026
response to other organism GO:0051707 220 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
cellular response to stress GO:0033554 269 0.026
ion transmembrane transport GO:0034220 365 0.025
regulation of signal transduction GO:0009966 318 0.025
response to biotic stimulus GO:0009607 226 0.025
response to nutrient GO:0007584 248 0.024
brain development GO:0007420 247 0.024
single organism biosynthetic process GO:0044711 342 0.024
alpha amino acid metabolic process GO:1901605 71 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.024
response to extracellular stimulus GO:0009991 380 0.024
cellular catabolic process GO:0044248 295 0.024
reproduction GO:0000003 245 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
response to oxygen levels GO:0070482 265 0.023
circulatory system process GO:0003013 183 0.023
cellular homeostasis GO:0019725 252 0.023
cation transport GO:0006812 382 0.023
wound healing GO:0042060 122 0.023
apoptotic process GO:0006915 381 0.023
central nervous system development GO:0007417 311 0.023
homeostatic process GO:0042592 331 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
ribonucleoside metabolic process GO:0009119 174 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
regulation of cellular localization GO:0060341 263 0.022
blood circulation GO:0008015 183 0.022
protein phosphorylation GO:0006468 345 0.022
response to decreased oxygen levels GO:0036293 237 0.022
nucleoside metabolic process GO:0009116 179 0.022
cation homeostasis GO:0055080 195 0.022
positive regulation of molecular function GO:0044093 230 0.022
regulation of cell development GO:0060284 263 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
macromolecular complex assembly GO:0065003 273 0.021
cell projection organization GO:0030030 302 0.021
regulation of apoptotic process GO:0042981 335 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
neuron projection development GO:0031175 273 0.021
response to cytokine GO:0034097 215 0.021
response to growth factor GO:0070848 189 0.021
programmed cell death GO:0012501 392 0.021
regulation of response to stress GO:0080134 126 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
regulation of protein modification process GO:0031399 194 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
regulation of hydrolase activity GO:0051336 143 0.020
nucleotide metabolic process GO:0009117 279 0.020
purine nucleoside triphosphate metabolic process GO:0009144 141 0.020
regulation of system process GO:0044057 208 0.020
signal transduction by phosphorylation GO:0023014 144 0.020
multicellular organismal signaling GO:0035637 44 0.020
response to acid chemical GO:0001101 222 0.020
monocarboxylic acid metabolic process GO:0032787 152 0.020
protein complex biogenesis GO:0070271 263 0.020
regulation of locomotion GO:0040012 148 0.020
single organism reproductive process GO:0044702 297 0.020
cellular response to lipid GO:0071396 201 0.020
cardiac conduction GO:0061337 2 0.019
positive regulation of nervous system development GO:0051962 178 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
anion transport GO:0006820 178 0.019
regulation of cell proliferation GO:0042127 359 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
cation transmembrane transport GO:0098655 263 0.019
neurological system process GO:0050877 219 0.019
sulfur compound metabolic process GO:0006790 70 0.019
regulation of phosphorylation GO:0042325 248 0.019
regulation of cellular component movement GO:0051270 150 0.019
protein localization GO:0008104 191 0.019
ras protein signal transduction GO:0007265 29 0.019
regulation of protein metabolic process GO:0051246 289 0.019
positive regulation of cell death GO:0010942 184 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
cellular cation homeostasis GO:0030003 180 0.018
heart morphogenesis GO:0003007 3 0.018
response to hypoxia GO:0001666 231 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
regulation of nervous system development GO:0051960 264 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
multicellular organism reproduction GO:0032504 233 0.018
cellular response to abiotic stimulus GO:0071214 85 0.018
response to bacterium GO:0009617 200 0.018
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
regulation of hormone levels GO:0010817 187 0.018
single organism intracellular transport GO:1902582 166 0.017
metal ion homeostasis GO:0055065 186 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
response to hexose GO:0009746 144 0.017
oxidation reduction process GO:0055114 304 0.017
regulation of neurogenesis GO:0050767 247 0.017
intracellular transport GO:0046907 185 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
reproductive process GO:0022414 372 0.017
sexual reproduction GO:0019953 148 0.017
protein complex assembly GO:0006461 263 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
defense response GO:0006952 194 0.016
organophosphate catabolic process GO:0046434 148 0.016
negative regulation of molecular function GO:0044092 133 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
sulfur compound biosynthetic process GO:0044272 19 0.016
nucleoside triphosphate metabolic process GO:0009141 144 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
cellular lipid metabolic process GO:0044255 208 0.015
lipid biosynthetic process GO:0008610 128 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
cell communication involved in cardiac conduction GO:0086065 2 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
positive regulation of cell development GO:0010720 176 0.015
immune system process GO:0002376 204 0.015
regulation of response to external stimulus GO:0032101 106 0.015
nitrogen compound transport GO:0071705 229 0.015
organic acid biosynthetic process GO:0016053 83 0.015
axis specification GO:0009798 4 0.015
jak stat cascade GO:0007259 26 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
carboxylic acid biosynthetic process GO:0046394 83 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
aging GO:0007568 241 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
positive regulation of transport GO:0051050 245 0.015
smooth muscle cell proliferation GO:0048659 77 0.015
cellular response to cytokine stimulus GO:0071345 127 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
peptidyl amino acid modification GO:0018193 126 0.014
head development GO:0060322 247 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
regulation of cell projection organization GO:0031344 175 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
regulation of ion transport GO:0043269 245 0.014
lipid metabolic process GO:0006629 283 0.014
regulation of membrane potential GO:0042391 110 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
transmission of nerve impulse GO:0019226 42 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
tissue development GO:0009888 252 0.013
response to carbohydrate GO:0009743 183 0.013
cellular response to external stimulus GO:0071496 118 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
establishment of tissue polarity GO:0007164 2 0.013
regulation of neuron differentiation GO:0045664 208 0.013
response to monosaccharide GO:0034284 159 0.013
proteolysis GO:0006508 175 0.013
cellular response to biotic stimulus GO:0071216 59 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
eye morphogenesis GO:0048592 4 0.013
gland development GO:0048732 155 0.013
regulation of programmed cell death GO:0043067 341 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
growth GO:0040007 165 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
reproductive system development GO:0061458 128 0.012
response to purine containing compound GO:0014074 126 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
regulation of secretion GO:0051046 224 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
cell part morphogenesis GO:0032990 123 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
cellular component morphogenesis GO:0032989 155 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
protein homooligomerization GO:0051260 91 0.012
response to estrogen GO:0043627 232 0.012
response to glucose GO:0009749 136 0.012
response to interleukin 1 GO:0070555 55 0.012
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.012
dna metabolic process GO:0006259 96 0.012
cardiac chamber development GO:0003205 1 0.012
establishment of protein localization GO:0045184 141 0.012
positive regulation of protein modification process GO:0031401 142 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
cellular ion homeostasis GO:0006873 184 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of neuron projection development GO:0010975 161 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
coenzyme metabolic process GO:0006732 86 0.012
cellular metal ion homeostasis GO:0006875 172 0.011
anterior posterior pattern specification GO:0009952 1 0.011
macromolecule catabolic process GO:0009057 58 0.011
alcohol metabolic process GO:0006066 77 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
protein transport GO:0015031 132 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
mesenchymal cell proliferation GO:0010463 4 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
multicellular organism growth GO:0035264 1 0.011
divalent inorganic cation transport GO:0072511 134 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
single organism organelle organization GO:1902589 180 0.011
regulation of mesenchymal cell proliferation GO:0010464 4 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
gastrulation GO:0007369 2 0.011
rhythmic process GO:0048511 156 0.011
cell cell signaling GO:0007267 335 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
actin filament based process GO:0030029 86 0.011
response to vitamin GO:0033273 131 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
action potential GO:0001508 54 0.011
secretion by cell GO:0032940 248 0.011
purine containing compound catabolic process GO:0072523 138 0.011
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.011
single organism membrane organization GO:0044802 74 0.011
response to reactive oxygen species GO:0000302 120 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
regulation of response to wounding GO:1903034 69 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
epithelial cell differentiation GO:0030855 71 0.010
bmp signaling pathway GO:0030509 4 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
protein complex subunit organization GO:0071822 302 0.010
regulation of kinase activity GO:0043549 117 0.010
spermatogenesis GO:0007283 99 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
regulation of cellular response to stress GO:0080135 49 0.010
monocarboxylic acid transport GO:0015718 52 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
reproductive structure development GO:0048608 128 0.010
lipid transport GO:0006869 61 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
gonad development GO:0008406 104 0.010
cardiovascular system development GO:0072358 134 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010

H6pd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.020
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
inherited metabolic disorder DOID:655 0 0.013
central nervous system disease DOID:331 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010