Rattus norvegicus

77 known processes

Ugt1a1

UDP glucuronosyltransferase 1 family, polypeptide A1

(Aliases: Ugt1,UDPGT 1-1,Udpgt)

Ugt1a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
halogenated hydrocarbon metabolic process GO:0042197 4 0.654
Rat
biphenyl catabolic process GO:0070980 2 0.596
coumarin catabolic process GO:0046226 3 0.364
Rat
phenylpropanoid catabolic process GO:0046271 3 0.298
Rat
response to nutrient GO:0007584 248 0.229
lipid metabolic process GO:0006629 283 0.221
Rat
response to peptide hormone GO:0043434 278 0.220
Rat
cellular response to lipid GO:0071396 201 0.214
cellular response to organic cyclic compound GO:0071407 202 0.210
monocarboxylic acid metabolic process GO:0032787 152 0.202
Mouse
cellular response to hormone stimulus GO:0032870 247 0.186
response to extracellular stimulus GO:0009991 380 0.176
organic acid metabolic process GO:0006082 292 0.168
Mouse
response to nutrient levels GO:0031667 370 0.159
cellular lipid metabolic process GO:0044255 208 0.158
oxoacid metabolic process GO:0043436 290 0.148
Mouse
4 chlorobiphenyl metabolic process GO:0018880 1 0.142
Rat
carboxylic acid metabolic process GO:0019752 289 0.134
Mouse
response to inorganic substance GO:0010035 377 0.131
cellular response to oxygen containing compound GO:1901701 386 0.124
response to peptide GO:1901652 292 0.117
Rat
response to xenobiotic stimulus GO:0009410 23 0.117
liver development GO:0001889 90 0.115
cellular response to steroid hormone stimulus GO:0071383 93 0.112
gland development GO:0048732 155 0.110
cellular response to xenobiotic stimulus GO:0071466 19 0.106
response to corticosteroid GO:0031960 235 0.106
homeostatic process GO:0042592 331 0.102
hepaticobiliary system development GO:0061008 90 0.101
cellular response to glucocorticoid stimulus GO:0071385 68 0.087
multi organism reproductive process GO:0044703 262 0.087
cellular response to corticosteroid stimulus GO:0071384 69 0.086
organic substance catabolic process GO:1901575 316 0.084
organ regeneration GO:0031100 101 0.083
single organism carbohydrate metabolic process GO:0044723 118 0.078
Mouse
aromatic compound catabolic process GO:0019439 168 0.075
behavior GO:0007610 205 0.075
Fly
steroid metabolic process GO:0008202 73 0.075
Rat
response to acid chemical GO:0001101 222 0.074
cellular response to organonitrogen compound GO:0071417 197 0.073
Rat
chlorinated hydrocarbon metabolic process GO:0042196 4 0.072
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.070
benzene containing compound metabolic process GO:0042537 22 0.069
response to estrogen GO:0043627 232 0.066
cellular amino acid metabolic process GO:0006520 107 0.066
positive regulation of cell communication GO:0010647 271 0.066
cellular response to ethanol GO:0071361 13 0.064
sensory perception GO:0007600 101 0.064
Rat Fly
single organism biosynthetic process GO:0044711 342 0.060
small molecule biosynthetic process GO:0044283 124 0.059
cellular response to endogenous stimulus GO:0071495 377 0.054
reproductive process GO:0022414 372 0.054
single organism reproductive process GO:0044702 297 0.054
catabolic process GO:0009056 351 0.054
single organism catabolic process GO:0044712 283 0.053
Rat
apoptotic process GO:0006915 381 0.053
cellular catabolic process GO:0044248 295 0.051
response to ethanol GO:0045471 162 0.051
cellular hormone metabolic process GO:0034754 49 0.050
Rat
response to ketone GO:1901654 182 0.050
Rat
xenobiotic metabolic process GO:0006805 19 0.050
macromolecular complex assembly GO:0065003 273 0.050
hormone metabolic process GO:0042445 69 0.047
Rat
ion transmembrane transport GO:0034220 365 0.045
female pregnancy GO:0007565 122 0.045
cellular response to peptide GO:1901653 133 0.044
Rat
carboxylic acid biosynthetic process GO:0046394 83 0.044
response to glucocorticoid GO:0051384 223 0.044
cellular component assembly GO:0022607 360 0.043
cellular response to alcohol GO:0097306 87 0.043
regulation of cellular localization GO:0060341 263 0.043
positive regulation of cellular biosynthetic process GO:0031328 295 0.042
neurological system process GO:0050877 219 0.042
Rat Fly
positive regulation of cell proliferation GO:0008284 249 0.040
response to other organism GO:0051707 220 0.040
response to dexamethasone GO:0071548 49 0.040
response to oxygen levels GO:0070482 265 0.039
response to vitamin GO:0033273 131 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
lipid biosynthetic process GO:0008610 128 0.039
steroid catabolic process GO:0006706 5 0.039
Rat
carbohydrate metabolic process GO:0005975 130 0.038
Mouse
response to decreased oxygen levels GO:0036293 237 0.037
rhythmic process GO:0048511 156 0.037
neuronal action potential GO:0019228 35 0.037
response to alkaloid GO:0043279 132 0.037
response to estradiol GO:0032355 164 0.036
regeneration GO:0031099 163 0.036
transmembrane transport GO:0055085 412 0.036
fatty acid metabolic process GO:0006631 99 0.036
heterocycle catabolic process GO:0046700 167 0.036
Rat
salivary gland development GO:0007431 3 0.036
female gonad development GO:0008585 53 0.036
regulation of phosphate metabolic process GO:0019220 349 0.036
reproduction GO:0000003 245 0.036
regulation of cell proliferation GO:0042127 359 0.036
response to growth factor GO:0070848 189 0.035
regulation of cellular ketone metabolic process GO:0010565 27 0.035
programmed cell death GO:0012501 392 0.035
regulation of phosphorus metabolic process GO:0051174 349 0.035
organophosphate metabolic process GO:0019637 370 0.035
cellular response to nitrogen compound GO:1901699 210 0.035
Rat
circulatory system process GO:0003013 183 0.034
response to metal ion GO:0010038 253 0.034
xenobiotic catabolic process GO:0042178 7 0.033
multicellular organismal signaling GO:0035637 44 0.032
response to biotic stimulus GO:0009607 226 0.032
sulfur compound metabolic process GO:0006790 70 0.032
central nervous system development GO:0007417 311 0.032
cellular response to testosterone stimulus GO:0071394 5 0.032
Rat
cellular component biogenesis GO:0044085 368 0.032
lipid modification GO:0030258 52 0.032
response to testosterone GO:0033574 55 0.031
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.031
aging GO:0007568 241 0.030
positive regulation of response to stimulus GO:0048584 285 0.030
negative regulation of cell death GO:0060548 229 0.030
cellular amine metabolic process GO:0044106 38 0.030
alcohol metabolic process GO:0006066 77 0.030
cellular response to external stimulus GO:0071496 118 0.030
alpha amino acid metabolic process GO:1901605 71 0.029
action potential GO:0001508 54 0.029
brain development GO:0007420 247 0.029
feeding behavior GO:0007631 53 0.029
urogenital system development GO:0001655 78 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
regulation of system process GO:0044057 208 0.029
regulation of cell differentiation GO:0045595 320 0.029
amine metabolic process GO:0009308 38 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
inflammatory response GO:0006954 150 0.028
glycerolipid metabolic process GO:0046486 67 0.028
regulation of molecular function GO:0065009 398 0.028
cellular response to peptide hormone stimulus GO:0071375 120 0.028
Rat
negative regulation of programmed cell death GO:0043069 183 0.028
regulation of transmembrane transport GO:0034762 122 0.028
cellular response to ketone GO:1901655 51 0.027
Rat
cellular ion homeostasis GO:0006873 184 0.027
regulation of programmed cell death GO:0043067 341 0.027
multicellular organism reproduction GO:0032504 233 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
defense response GO:0006952 194 0.027
coumarin metabolic process GO:0009804 5 0.026
Rat
coenzyme metabolic process GO:0006732 86 0.026
organic acid biosynthetic process GO:0016053 83 0.026
organic acid catabolic process GO:0016054 49 0.026
monovalent inorganic cation transport GO:0015672 172 0.026
positive regulation of secretion by cell GO:1903532 128 0.026
ion homeostasis GO:0050801 212 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
epithelium development GO:0060429 96 0.026
secretion GO:0046903 307 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
response to external biotic stimulus GO:0043207 221 0.025
regulation of lipid metabolic process GO:0019216 68 0.025
carboxylic acid catabolic process GO:0046395 49 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
protein oligomerization GO:0051259 191 0.025
response to bacterium GO:0009617 200 0.024
small molecule catabolic process GO:0044282 59 0.024
blood circulation GO:0008015 183 0.024
cytosolic calcium ion homeostasis GO:0051480 140 0.024
muscle structure development GO:0061061 87 0.024
positive regulation of signaling GO:0023056 270 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
cardiovascular system development GO:0072358 134 0.024
chemical homeostasis GO:0048878 292 0.024
head development GO:0060322 247 0.024
regulation of ion transport GO:0043269 245 0.023
growth GO:0040007 165 0.023
organic hydroxy compound metabolic process GO:1901615 115 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
cellular calcium ion homeostasis GO:0006874 160 0.023
nucleotide metabolic process GO:0009117 279 0.022
regulation of apoptotic process GO:0042981 335 0.022
response to radiation GO:0009314 137 0.022
peptidyl amino acid modification GO:0018193 126 0.022
renal system development GO:0072001 67 0.022
response to lipopolysaccharide GO:0032496 191 0.022
cellular homeostasis GO:0019725 252 0.022
reproductive structure development GO:0048608 128 0.022
positive regulation of molecular function GO:0044093 230 0.022
lipid catabolic process GO:0016042 46 0.022
Rat
negative regulation of apoptotic process GO:0043066 181 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.022
cellular cation homeostasis GO:0030003 180 0.022
cation homeostasis GO:0055080 195 0.022
positive regulation of developmental process GO:0051094 283 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
positive regulation of transport GO:0051050 245 0.022
developmental process involved in reproduction GO:0003006 159 0.021
cation transport GO:0006812 382 0.021
synaptic transmission GO:0007268 235 0.021
regulation of secretion GO:0051046 224 0.021
carbohydrate derivative catabolic process GO:1901136 147 0.021
monosaccharide metabolic process GO:0005996 61 0.021
Mouse
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
regulation of anatomical structure size GO:0090066 135 0.021
protein autophosphorylation GO:0046777 66 0.020
cellular amino acid biosynthetic process GO:0008652 32 0.020
axis specification GO:0009798 4 0.020
regulation of secretion by cell GO:1903530 208 0.020
cellular ketone metabolic process GO:0042180 51 0.020
secondary metabolic process GO:0019748 15 0.020
Rat
estrogen catabolic process GO:0006711 1 0.020
Rat
regulation of neuron projection development GO:0010975 161 0.020
response to glucose GO:0009749 136 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
response to wounding GO:0009611 254 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.019
protein complex subunit organization GO:0071822 302 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
peptidyl tyrosine modification GO:0018212 72 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
protein complex assembly GO:0006461 263 0.019
response to oxidative stress GO:0006979 186 0.019
cellular response to extracellular stimulus GO:0031668 73 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
salivary gland morphogenesis GO:0007435 1 0.019
response to reactive oxygen species GO:0000302 120 0.019
rna biosynthetic process GO:0032774 380 0.018
tube development GO:0035295 89 0.018
response to insulin GO:0032868 133 0.018
lipid oxidation GO:0034440 30 0.018
regulation of signal transduction GO:0009966 318 0.018
kidney development GO:0001822 67 0.018
oxidation reduction process GO:0055114 304 0.018
lauric acid metabolic process GO:0048252 4 0.018
metal ion homeostasis GO:0055065 186 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
ovulation cycle GO:0042698 67 0.018
positive regulation of blood circulation GO:1903524 65 0.017
organic hydroxy compound biosynthetic process GO:1901617 51 0.017
purine containing compound metabolic process GO:0072521 253 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
actin filament based process GO:0030029 86 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
multi multicellular organism process GO:0044706 138 0.017
positive regulation of signal transduction GO:0009967 175 0.017
circadian rhythm GO:0007623 88 0.017
gamete generation GO:0007276 124 0.017
cell cell signaling GO:0007267 335 0.017
cellular response to growth hormone stimulus GO:0071378 6 0.017
Rat
transmission of nerve impulse GO:0019226 42 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
regulation of response to external stimulus GO:0032101 106 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
macromolecule localization GO:0033036 252 0.016
reproductive system development GO:0061458 128 0.016
response to monosaccharide GO:0034284 159 0.016
metal ion transport GO:0030001 289 0.016
protein complex biogenesis GO:0070271 263 0.016
development of primary female sexual characteristics GO:0046545 56 0.016
protein heterooligomerization GO:0051291 89 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
female sex differentiation GO:0046660 59 0.016
protein phosphorylation GO:0006468 345 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
biphenyl metabolic process GO:0018879 10 0.016
neuron differentiation GO:0030182 368 0.016
heart development GO:0007507 72 0.016
calcium ion homeostasis GO:0055074 162 0.016
sex differentiation GO:0007548 113 0.015
tissue morphogenesis GO:0048729 22 0.015
nucleoside metabolic process GO:0009116 179 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
regulation of reactive oxygen species metabolic process GO:2000377 26 0.015
ribonucleoside monophosphate metabolic process GO:0009161 88 0.015
ras protein signal transduction GO:0007265 29 0.015
regulation of multicellular organismal development GO:2000026 376 0.015
tissue development GO:0009888 252 0.015
vasoconstriction GO:0042310 54 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
cofactor metabolic process GO:0051186 95 0.015
response to low density lipoprotein particle GO:0055098 4 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
cellular response to insulin stimulus GO:0032869 81 0.015
diterpenoid metabolic process GO:0016101 33 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
response to organophosphorus GO:0046683 102 0.014
respiratory system development GO:0060541 45 0.014
cellular response to dexamethasone stimulus GO:0071549 36 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
regulation of phosphorylation GO:0042325 248 0.014
negative regulation of innate immune response GO:0045824 4 0.014
alkaloid metabolic process GO:0009820 3 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
response to carbohydrate GO:0009743 183 0.014
regulation of hormone levels GO:0010817 187 0.014
Rat
rna metabolic process GO:0016070 406 0.014
linoleic acid metabolic process GO:0043651 4 0.014
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.014
calcium ion transport GO:0006816 131 0.014
heart morphogenesis GO:0003007 3 0.014
peptide biosynthetic process GO:0043043 3 0.013
vascular process in circulatory system GO:0003018 96 0.013
response to purine containing compound GO:0014074 126 0.013
cell activation GO:0001775 97 0.013
neuron projection development GO:0031175 273 0.013
regulation of catalytic activity GO:0050790 304 0.013
protein homooligomerization GO:0051260 91 0.013
intracellular signal transduction GO:0035556 314 0.013
hormone catabolic process GO:0042447 2 0.013
Rat
regulation of body fluid levels GO:0050878 90 0.013
response to mechanical stimulus GO:0009612 134 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
positive regulation of hormone secretion GO:0046887 65 0.013
epithelial cell proliferation GO:0050673 54 0.013
negative regulation of metabolic process GO:0009892 331 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
positive regulation of ion transport GO:0043270 94 0.012
cell type specific apoptotic process GO:0097285 134 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
synaptic transmission glutamatergic GO:0035249 33 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.012
cellular modified amino acid metabolic process GO:0006575 61 0.012
positive regulation of lipid kinase activity GO:0090218 2 0.012
hexose transport GO:0008645 29 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
striated muscle tissue development GO:0014706 58 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
branching morphogenesis of an epithelial tube GO:0048754 14 0.012
regulation of protein metabolic process GO:0051246 289 0.012
regulation of growth GO:0040008 105 0.012
developmental growth GO:0048589 100 0.012
carbohydrate biosynthetic process GO:0016051 42 0.012
eye morphogenesis GO:0048592 4 0.012
cellular amino acid catabolic process GO:0009063 21 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
regulation of blood vessel size GO:0050880 89 0.012
response to activity GO:0014823 73 0.012
estrogen metabolic process GO:0008210 11 0.012
Rat
response to hexose GO:0009746 144 0.012
response to hydrogen peroxide GO:0042542 89 0.012
establishment of tissue polarity GO:0007164 2 0.012
organelle organization GO:0006996 266 0.012
regulation of metal ion transport GO:0010959 118 0.012
response to mercury ion GO:0046689 15 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
isoprenoid metabolic process GO:0006720 45 0.012
regulation of hormone secretion GO:0046883 106 0.012
cellular macromolecule localization GO:0070727 122 0.011
tissue remodeling GO:0048771 40 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
connective tissue development GO:0061448 33 0.011
ossification GO:0001503 70 0.011
regulation of cell growth GO:0001558 85 0.011
circulatory system development GO:0072359 134 0.011
positive regulation of protein modification process GO:0031401 142 0.011
vasculogenesis GO:0001570 3 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
acute phase response GO:0006953 20 0.011
sequestering of calcium ion GO:0051208 8 0.011
response to starvation GO:0042594 59 0.011
regulation of transferase activity GO:0051338 123 0.011
gonad development GO:0008406 104 0.011
regulation of gluconeogenesis GO:0006111 4 0.011
purine nucleoside monophosphate metabolic process GO:0009126 84 0.011
regulation of hydrolase activity GO:0051336 143 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
skeletal muscle tissue development GO:0007519 31 0.011
response to ammonium ion GO:0060359 71 0.011
monocarboxylic acid biosynthetic process GO:0072330 48 0.011
cellular chemical homeostasis GO:0055082 247 0.011
regulation of locomotion GO:0040012 148 0.011
lymphocyte homeostasis GO:0002260 2 0.011
regulation of tolerance induction to nonself antigen GO:0002655 1 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
cell part morphogenesis GO:0032990 123 0.011
muscle system process GO:0003012 115 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.011
regulation of peptide transport GO:0090087 87 0.011
sexual reproduction GO:0019953 148 0.011
negative regulation of transport GO:0051051 136 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
limb morphogenesis GO:0035108 4 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
regulation of mapk cascade GO:0043408 116 0.011
lipid storage GO:0019915 1 0.011
male gamete generation GO:0048232 99 0.011
carbohydrate homeostasis GO:0033500 75 0.011
organophosphate catabolic process GO:0046434 148 0.011
rho protein signal transduction GO:0007266 11 0.011
response to vitamin d GO:0033280 34 0.011
regulation of membrane potential GO:0042391 110 0.011
secretion by cell GO:0032940 248 0.011
cellular response to stress GO:0033554 269 0.011
cell cycle checkpoint GO:0000075 2 0.011
response to nicotine GO:0035094 51 0.011
cellular modified amino acid biosynthetic process GO:0042398 18 0.011
regulation of muscle system process GO:0090257 79 0.010
nucleic acid templated transcription GO:0097659 379 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
actin cytoskeleton organization GO:0030036 73 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.010
embryonic pattern specification GO:0009880 1 0.010
glucose homeostasis GO:0042593 75 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
response to hypoxia GO:0001666 231 0.010
nucleoside monophosphate metabolic process GO:0009123 93 0.010
regulation of nervous system development GO:0051960 264 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
spermatogenesis GO:0007283 99 0.010
regulation of transporter activity GO:0032409 50 0.010
body fluid secretion GO:0007589 41 0.010
positive regulation of peptide secretion GO:0002793 52 0.010
respiratory tube development GO:0030323 43 0.010
fatty acid oxidation GO:0019395 29 0.010
cell morphogenesis GO:0000902 142 0.010
regulation of epithelial cell proliferation GO:0050678 49 0.010
response to cytokine GO:0034097 215 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
regulation of calcium ion transport GO:0051924 77 0.010
muscle organ development GO:0007517 50 0.010

Ugt1a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
cardiovascular system disease DOID:1287 0 0.016
central nervous system disease DOID:331 0 0.012
hypertension DOID:10763 0 0.011
artery disease DOID:0050828 0 0.011
vascular disease DOID:178 0 0.011
disease of cellular proliferation DOID:14566 0 0.010