Rattus norvegicus

0 known processes

Melk

maternal embryonic leucine zipper kinase

Melk biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.164
double strand break repair GO:0006302 1 0.143
protein localization to chromosome centromeric region GO:0071459 1 0.101
chromosome segregation GO:0007059 2 0.061
cell cycle GO:0007049 101 0.058
regulation of cell proliferation GO:0042127 359 0.052
mitotic sister chromatid separation GO:0051306 1 0.051
negative regulation of metabolic process GO:0009892 331 0.049
positive regulation of cell proliferation GO:0008284 249 0.043
regulation of phosphorylation GO:0042325 248 0.042
regulation of programmed cell death GO:0043067 341 0.041
regulation of chromosome segregation GO:0051983 1 0.041
regulation of transcription dna templated GO:0006355 374 0.039
cellular component movement GO:0006928 248 0.039
sexual reproduction GO:0019953 148 0.039
macromolecular complex subunit organization GO:0043933 339 0.037
cellular component biogenesis GO:0044085 368 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
response to metal ion GO:0010038 253 0.036
cellular component assembly GO:0022607 360 0.036
oxoacid metabolic process GO:0043436 290 0.036
apoptotic process GO:0006915 381 0.035
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
negative regulation of cell death GO:0060548 229 0.034
response to oxygen levels GO:0070482 265 0.034
male meiosis GO:0007140 1 0.033
dna packaging GO:0006323 4 0.033
carboxylic acid metabolic process GO:0019752 289 0.032
cellular amine metabolic process GO:0044106 38 0.032
single organism catabolic process GO:0044712 283 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
positive regulation of gene expression GO:0010628 244 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
amine metabolic process GO:0009308 38 0.031
reproduction GO:0000003 245 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.030
rna metabolic process GO:0016070 406 0.030
multi organism reproductive process GO:0044703 262 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
positive regulation of phosphorylation GO:0042327 177 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
meiotic cell cycle process GO:1903046 3 0.027
regulation of protein modification process GO:0031399 194 0.027
protein phosphorylation GO:0006468 345 0.027
regulation of cellular component organization GO:0051128 368 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.026
multicellular organism reproduction GO:0032504 233 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
positive regulation of developmental process GO:0051094 283 0.026
g1 s transition of mitotic cell cycle GO:0000082 12 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
cellular response to stress GO:0033554 269 0.026
programmed cell death GO:0012501 392 0.025
positive regulation of synapse maturation GO:0090129 2 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
single organism biosynthetic process GO:0044711 342 0.024
chromosome organization GO:0051276 36 0.024
regulation of mitotic sister chromatid separation GO:0010965 1 0.024
response to amine GO:0014075 46 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
mitotic sister chromatid segregation GO:0000070 1 0.024
nucleotide metabolic process GO:0009117 279 0.023
metaphase anaphase transition of cell cycle GO:0044784 1 0.023
response to decreased oxygen levels GO:0036293 237 0.023
meiosis i GO:0007127 2 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
reproductive process GO:0022414 372 0.022
regulation of apoptotic process GO:0042981 335 0.022
peptidyl amino acid modification GO:0018193 126 0.022
organelle organization GO:0006996 266 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
regeneration GO:0031099 163 0.021
organophosphate metabolic process GO:0019637 370 0.021
cell cycle checkpoint GO:0000075 2 0.021
rna biosynthetic process GO:0032774 380 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
response to transition metal nanoparticle GO:1990267 122 0.021
catabolic process GO:0009056 351 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
nucleosome organization GO:0034728 1 0.021
protein complex biogenesis GO:0070271 263 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
protein complex subunit organization GO:0071822 302 0.020
nucleic acid templated transcription GO:0097659 379 0.020
transcription dna templated GO:0006351 377 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
positive regulation of protein modification process GO:0031401 142 0.020
regulation of sister chromatid segregation GO:0033045 1 0.020
cellular ketone metabolic process GO:0042180 51 0.020
regulation of mitotic sister chromatid segregation GO:0033047 1 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
centrosome organization GO:0051297 1 0.020
aromatic compound catabolic process GO:0019439 168 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.019
single organism reproductive process GO:0044702 297 0.019
response to hypoxia GO:0001666 231 0.019
regulation of growth GO:0040008 105 0.019
positive regulation of biosynthetic process GO:0009891 319 0.018
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.018
purine containing compound metabolic process GO:0072521 253 0.018
chromosome separation GO:0051304 1 0.018
cell cycle process GO:0022402 57 0.018
response to ethanol GO:0045471 162 0.018
mitotic cell cycle phase transition GO:0044772 20 0.018
cell cycle dna replication GO:0044786 1 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
intracellular signal transduction GO:0035556 314 0.017
cell cell signaling GO:0007267 335 0.017
cellular catabolic process GO:0044248 295 0.017
macromolecular complex assembly GO:0065003 273 0.017
regulation of molecular function GO:0065009 398 0.016
protein complex assembly GO:0006461 263 0.016
cell growth GO:0016049 104 0.016
regulation of signal transduction GO:0009966 318 0.016
spermatogenesis GO:0007283 99 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
cellular response to endogenous stimulus GO:0071495 377 0.016
regulation of response to stress GO:0080134 126 0.016
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.016
cerebellar purkinje cell differentiation GO:0021702 1 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
response to inorganic substance GO:0010035 377 0.015
positive regulation of signaling GO:0023056 270 0.015
sister chromatid segregation GO:0000819 1 0.015
central nervous system development GO:0007417 311 0.015
multi multicellular organism process GO:0044706 138 0.015
regulation of rna metabolic process GO:0051252 391 0.015
cellular lipid metabolic process GO:0044255 208 0.015
regulation of cell cycle GO:0051726 73 0.015
response to ddt GO:0046680 1 0.015
response to glucocorticoid GO:0051384 223 0.015
growth GO:0040007 165 0.015
organic substance catabolic process GO:1901575 316 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
organonitrogen compound catabolic process GO:1901565 179 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
gamete generation GO:0007276 124 0.014
cell type specific apoptotic process GO:0097285 134 0.014
male gamete generation GO:0048232 99 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.014
circulatory system development GO:0072359 134 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
response to purine containing compound GO:0014074 126 0.014
protein localization GO:0008104 191 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
regulation of transferase activity GO:0051338 123 0.013
dna recombination GO:0006310 3 0.013
positive regulation of synaptic plasticity GO:0031915 3 0.013
macromolecule localization GO:0033036 252 0.013
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
cell projection organization GO:0030030 302 0.013
mitotic dna damage checkpoint GO:0044773 1 0.013
regulation of cell differentiation GO:0045595 320 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
neuron projection development GO:0031175 273 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
regulation of kinase activity GO:0043549 117 0.013
organophosphate catabolic process GO:0046434 148 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
metaphase plate congression GO:0051310 1 0.013
spindle organization GO:0007051 2 0.012
anterior posterior pattern specification GO:0009952 1 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
heterocycle catabolic process GO:0046700 167 0.012
positive regulation of growth GO:0045927 55 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
dna metabolic process GO:0006259 96 0.012
muscle cell proliferation GO:0033002 84 0.012
negative regulation of gene expression GO:0010629 199 0.012
cellular macromolecule localization GO:0070727 122 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
centrosome cycle GO:0007098 1 0.012
positive regulation of triglyceride metabolic process GO:0090208 4 0.012
positive regulation of dna metabolic process GO:0051054 39 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
regulation of protein kinase activity GO:0045859 105 0.012
single organism intracellular transport GO:1902582 166 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
regulation of meiotic cell cycle GO:0051445 3 0.011
synaptic transmission GO:0007268 235 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
macromolecule catabolic process GO:0009057 58 0.011
regulation of organelle organization GO:0033043 80 0.011
cytoskeleton dependent cytokinesis GO:0061640 2 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
regulation of synaptic transmission GO:0050804 141 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
developmental maturation GO:0021700 25 0.011
developmental process involved in reproduction GO:0003006 159 0.011
mitotic spindle organization GO:0007052 2 0.011
aging GO:0007568 241 0.010
cardiovascular system development GO:0072358 134 0.010
single organism organelle organization GO:1902589 180 0.010
response to radiation GO:0009314 137 0.010
positive regulation of signal transduction GO:0009967 175 0.010
response to wounding GO:0009611 254 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
regulation of cell projection organization GO:0031344 175 0.010
chromatin assembly or disassembly GO:0006333 1 0.010
regulation of synaptic plasticity GO:0048167 70 0.010
nucleotide catabolic process GO:0009166 139 0.010
negative regulation of molecular function GO:0044092 133 0.010
response to acid chemical GO:0001101 222 0.010
transcription from rna polymerase ii promoter GO:0006366 252 0.010
regulation of nervous system development GO:0051960 264 0.010

Melk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org