Rattus norvegicus

80 known processes

Nr1h2

nuclear receptor subfamily 1, group H, member 2

(Aliases: OR-1)

Nr1h2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient levels GO:0031667 370 0.148
protein localization GO:0008104 191 0.119
Mouse
macromolecule localization GO:0033036 252 0.095
Human Mouse Worm
cellular response to endogenous stimulus GO:0071495 377 0.092
Rat
proteolysis GO:0006508 175 0.088
Mouse
cellular macromolecule localization GO:0070727 122 0.087
rna biosynthetic process GO:0032774 380 0.084
catabolic process GO:0009056 351 0.079
transcription dna templated GO:0006351 377 0.079
transcription from rna polymerase ii promoter GO:0006366 252 0.079
programmed cell death GO:0012501 392 0.079
intracellular transport GO:0046907 185 0.076
carboxylic acid metabolic process GO:0019752 289 0.075
Human
apoptotic process GO:0006915 381 0.073
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.073
response to nutrient GO:0007584 248 0.072
rna metabolic process GO:0016070 406 0.071
reproduction GO:0000003 245 0.067
Worm
cellular component assembly GO:0022607 360 0.065
Mouse
response to other organism GO:0051707 220 0.063
regulation of rna biosynthetic process GO:2001141 381 0.063
immune system process GO:0002376 204 0.060
regulation of nucleic acid templated transcription GO:1903506 380 0.059
regulation of cellular localization GO:0060341 263 0.059
Mouse
protein complex subunit organization GO:0071822 302 0.059
organic acid metabolic process GO:0006082 292 0.059
Human
protein transport GO:0015031 132 0.057
Mouse
regulation of rna metabolic process GO:0051252 391 0.056
tissue development GO:0009888 252 0.056
cellular catabolic process GO:0044248 295 0.055
positive regulation of nucleic acid templated transcription GO:1903508 197 0.055
single organism intracellular transport GO:1902582 166 0.055
nucleic acid templated transcription GO:0097659 379 0.055
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.054
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.054
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.053
reproductive process GO:0022414 372 0.053
response to molecule of bacterial origin GO:0002237 194 0.051
single organism reproductive process GO:0044702 297 0.050
positive regulation of transcription dna templated GO:0045893 197 0.049
establishment of protein localization GO:0045184 141 0.049
Mouse
macromolecular complex assembly GO:0065003 273 0.049
Mouse
response to lipopolysaccharide GO:0032496 191 0.047
response to extracellular stimulus GO:0009991 380 0.046
protein oligomerization GO:0051259 191 0.045
intracellular protein transport GO:0006886 79 0.044
protein complex biogenesis GO:0070271 263 0.044
positive regulation of rna metabolic process GO:0051254 203 0.043
negative regulation of metabolic process GO:0009892 331 0.042
ribonucleoside metabolic process GO:0009119 174 0.040
cellular response to peptide hormone stimulus GO:0071375 120 0.040
Rat
defense response GO:0006952 194 0.040
negative regulation of biosynthetic process GO:0009890 168 0.040
Human Mouse
multi organism reproductive process GO:0044703 262 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.038
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.038
Human Mouse
organic substance catabolic process GO:1901575 316 0.038
regulation of transcription dna templated GO:0006355 374 0.038
multicellular organism reproduction GO:0032504 233 0.037
cellular component biogenesis GO:0044085 368 0.037
Mouse
response to vitamin GO:0033273 131 0.036
regulation of molecular function GO:0065009 398 0.036
Human
lipid metabolic process GO:0006629 283 0.036
Human Mouse Rat
response to biotic stimulus GO:0009607 226 0.036
single organism catabolic process GO:0044712 283 0.035
protein targeting GO:0006605 61 0.035
protein complex assembly GO:0006461 263 0.034
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.034
Human Mouse
regulation of apoptotic process GO:0042981 335 0.034
response to bacterium GO:0009617 200 0.033
negative regulation of cellular biosynthetic process GO:0031327 161 0.033
Human Mouse
cell cell signaling GO:0007267 335 0.033
cellular response to organonitrogen compound GO:0071417 197 0.033
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.031
Human Mouse
positive regulation of biosynthetic process GO:0009891 319 0.031
regulation of ion transport GO:0043269 245 0.031
positive regulation of signaling GO:0023056 270 0.031
response to external biotic stimulus GO:0043207 221 0.030
regulation of cell proliferation GO:0042127 359 0.030
response to peptide hormone GO:0043434 278 0.030
Rat
regulation of multicellular organismal development GO:2000026 376 0.029
cation transport GO:0006812 382 0.029
negative regulation of gene expression GO:0010629 199 0.029
cellular protein localization GO:0034613 122 0.028
amine metabolic process GO:0009308 38 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
single organism membrane organization GO:0044802 74 0.027
positive regulation of gene expression GO:0010628 244 0.027
positive regulation of molecular function GO:0044093 230 0.027
Human
negative regulation of molecular function GO:0044092 133 0.027
multicellular organismal reproductive process GO:0048609 233 0.026
regulation of signal transduction GO:0009966 318 0.026
positive regulation of rna biosynthetic process GO:1902680 197 0.026
regulation of catalytic activity GO:0050790 304 0.026
Human
lipid biosynthetic process GO:0008610 128 0.026
Human
response to estrogen GO:0043627 232 0.026
response to peptide GO:1901652 292 0.026
Rat
cellular homeostasis GO:0019725 252 0.025
nucleotide metabolic process GO:0009117 279 0.025
anion transport GO:0006820 178 0.025
secretion GO:0046903 307 0.025
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.025
Rat
negative regulation of rna metabolic process GO:0051253 123 0.025
Human Mouse
nucleoside metabolic process GO:0009116 179 0.025
metal ion transport GO:0030001 289 0.024
protein import into nucleus GO:0006606 35 0.024
regulation of protein metabolic process GO:0051246 289 0.024
Human Mouse
regulation of intracellular signal transduction GO:1902531 218 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
purine nucleoside catabolic process GO:0006152 124 0.024
response to mechanical stimulus GO:0009612 134 0.024
nitrogen compound transport GO:0071705 229 0.023
response to heat GO:0009408 60 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
response to transition metal nanoparticle GO:1990267 122 0.023
positive regulation of transport GO:0051050 245 0.023
Human Mouse
cellular response to growth factor stimulus GO:0071363 162 0.023
intracellular signal transduction GO:0035556 314 0.023
cellular amide metabolic process GO:0043603 44 0.023
response to inorganic substance GO:0010035 377 0.023
positive regulation of cellular component movement GO:0051272 102 0.023
multi multicellular organism process GO:0044706 138 0.023
tube development GO:0035295 89 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
Human Mouse
response to oxygen levels GO:0070482 265 0.022
lipid storage GO:0019915 1 0.022
Human Mouse Worm
cellular amine metabolic process GO:0044106 38 0.022
response to organophosphorus GO:0046683 102 0.022
response to acid chemical GO:0001101 222 0.022
regulation of response to stress GO:0080134 126 0.021
synaptic transmission GO:0007268 235 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.021
heterocycle catabolic process GO:0046700 167 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
Human
response to decreased oxygen levels GO:0036293 237 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
enzyme linked receptor protein signaling pathway GO:0007167 116 0.021
Rat
regulation of protein localization GO:0032880 81 0.021
Mouse
regulation of cellular amine metabolic process GO:0033238 8 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
ribonucleoside catabolic process GO:0042454 126 0.021
regulation of programmed cell death GO:0043067 341 0.020
purine containing compound catabolic process GO:0072523 138 0.020
axis specification GO:0009798 4 0.020
organophosphate metabolic process GO:0019637 370 0.020
oxoacid metabolic process GO:0043436 290 0.020
Human
positive regulation of cell death GO:0010942 184 0.020
response to ethanol GO:0045471 162 0.020
regulation of synaptic transmission GO:0050804 141 0.020
cellular response to stress GO:0033554 269 0.020
purine nucleotide catabolic process GO:0006195 136 0.020
aging GO:0007568 241 0.020
vesicle mediated transport GO:0016192 181 0.020
Human
cellular response to hormone stimulus GO:0032870 247 0.020
Rat
negative regulation of protein metabolic process GO:0051248 114 0.020
Mouse
regulation of cell differentiation GO:0045595 320 0.020
antigen processing and presentation GO:0019882 2 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
Rat
single organism organelle organization GO:1902589 180 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
metal ion homeostasis GO:0055065 186 0.019
immune response GO:0006955 104 0.019
regulation of cell development GO:0060284 263 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
Human
regulation of phosphorylation GO:0042325 248 0.019
regulation of secretion by cell GO:1903530 208 0.019
Mouse
regulation of immune system process GO:0002682 123 0.019
regulation of fat cell differentiation GO:0045598 3 0.018
chemical homeostasis GO:0048878 292 0.018
Mouse Worm
regulation of anatomical structure size GO:0090066 135 0.018
organophosphate catabolic process GO:0046434 148 0.018
cellular chemical homeostasis GO:0055082 247 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
Human Mouse
ion homeostasis GO:0050801 212 0.018
response to hypoxia GO:0001666 231 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
multicellular organism growth GO:0035264 1 0.018
secretion by cell GO:0032940 248 0.018
Mouse
divalent inorganic cation homeostasis GO:0072507 165 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
Rat
protein homooligomerization GO:0051260 91 0.017
negative regulation of transport GO:0051051 136 0.017
Human
insulin like growth factor receptor signaling pathway GO:0048009 3 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
carboxylic acid transport GO:0046942 115 0.017
cellular response to lipid GO:0071396 201 0.017
nucleoside catabolic process GO:0009164 126 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
positive regulation of cell communication GO:0010647 271 0.017
negative regulation of cellular protein metabolic process GO:0032269 106 0.017
Mouse
response to growth factor GO:0070848 189 0.017
negative regulation of innate immune response GO:0045824 4 0.017
purine nucleoside triphosphate metabolic process GO:0009144 141 0.017
neuron differentiation GO:0030182 368 0.017
negative regulation of cell communication GO:0010648 158 0.017
rhythmic process GO:0048511 156 0.017
aromatic compound catabolic process GO:0019439 168 0.016
mesoderm development GO:0007498 2 0.016
response to cytokine GO:0034097 215 0.016
membrane organization GO:0061024 94 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
nucleotide catabolic process GO:0009166 139 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
Worm
purine ribonucleotide metabolic process GO:0009150 227 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
neurological system process GO:0050877 219 0.016
positive regulation of ion transport GO:0043270 94 0.016
ribonucleotide catabolic process GO:0009261 136 0.016
regulation of hydrolase activity GO:0051336 143 0.016
Human
response to ketone GO:1901654 182 0.016
cellular ketone metabolic process GO:0042180 51 0.016
Human
negative regulation of signaling GO:0023057 157 0.016
response to estradiol GO:0032355 164 0.016
transmembrane transport GO:0055085 412 0.016
anterior posterior pattern specification GO:0009952 1 0.016
cytoplasmic transport GO:0016482 115 0.016
chromosome segregation GO:0007059 2 0.016
female pregnancy GO:0007565 122 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
regulation of nervous system development GO:0051960 264 0.015
calcium ion homeostasis GO:0055074 162 0.015
macromolecule catabolic process GO:0009057 58 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
endocytosis GO:0006897 84 0.015
Human
response to metal ion GO:0010038 253 0.015
reproductive structure development GO:0048608 128 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
Human Mouse
amino acid transport GO:0006865 70 0.015
negative regulation of cellular component organization GO:0051129 83 0.015
Human
gland development GO:0048732 155 0.015
regulation of protein transport GO:0051223 68 0.015
Mouse
homeostatic process GO:0042592 331 0.015
Mouse Worm
regulation of neuron differentiation GO:0045664 208 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
neuronal action potential GO:0019228 35 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
reproductive system development GO:0061458 128 0.014
amide transport GO:0042886 105 0.014
signal release GO:0023061 145 0.014
cation homeostasis GO:0055080 195 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
Human Mouse
purine nucleotide metabolic process GO:0006163 229 0.014
regulation of neurogenesis GO:0050767 247 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
organic acid transport GO:0015849 116 0.014
peptide transport GO:0015833 97 0.014
action potential GO:0001508 54 0.014
protein maturation GO:0051604 68 0.014
Mouse
regulation of kinase activity GO:0043549 117 0.014
regulation of catabolic process GO:0009894 113 0.014
meiotic cell cycle process GO:1903046 3 0.014
response to radiation GO:0009314 137 0.014
cellular ion homeostasis GO:0006873 184 0.014
regulation of hormone levels GO:0010817 187 0.014
head development GO:0060322 247 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
response to carbohydrate GO:0009743 183 0.013
behavior GO:0007610 205 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
regulation of intracellular transport GO:0032386 65 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
lipid transport GO:0006869 61 0.013
Human Mouse
sexual reproduction GO:0019953 148 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
purine containing compound metabolic process GO:0072521 253 0.013
cellular cation homeostasis GO:0030003 180 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
Mouse
organelle organization GO:0006996 266 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
cytoskeleton dependent cytokinesis GO:0061640 2 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
negative regulation of protein maturation GO:1903318 47 0.013
Mouse
maintenance of location GO:0051235 17 0.013
Human Mouse Worm
cellular component movement GO:0006928 248 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
regulation of transferase activity GO:0051338 123 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
cell cycle process GO:0022402 57 0.013
positive regulation of developmental process GO:0051094 283 0.013
hepaticobiliary system development GO:0061008 90 0.013
response to retinoic acid GO:0032526 63 0.013
divalent metal ion transport GO:0070838 132 0.013
cellular lipid metabolic process GO:0044255 208 0.013
Human Mouse
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
nucleocytoplasmic transport GO:0006913 48 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
developmental process involved in reproduction GO:0003006 159 0.012
neuron development GO:0048666 286 0.012
gtp metabolic process GO:0046039 72 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
regulation of membrane potential GO:0042391 110 0.012
divalent inorganic cation transport GO:0072511 134 0.012
neuron projection development GO:0031175 273 0.012
protein targeting to nucleus GO:0044744 35 0.012
protein localization to organelle GO:0033365 57 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
ras protein signal transduction GO:0007265 29 0.012
establishment of organelle localization GO:0051656 37 0.012
positive regulation of locomotion GO:0040017 102 0.012
negative regulation of developmental process GO:0051093 125 0.012
response to alkaloid GO:0043279 132 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
liver development GO:0001889 90 0.012
localization of cell GO:0051674 202 0.012
dephosphorylation GO:0016311 98 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
Mouse
nucleoside triphosphate metabolic process GO:0009141 144 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
negative regulation of signal transduction GO:0009968 83 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
cellular response to abiotic stimulus GO:0071214 85 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
Mouse
single organism nuclear import GO:1902593 35 0.011
hormone transport GO:0009914 121 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
gtp catabolic process GO:0006184 71 0.011
lipid localization GO:0010876 62 0.011
Human Mouse Worm
acylglycerol metabolic process GO:0006639 21 0.011
Human
regulation of secretion GO:0051046 224 0.011
Mouse
peptide metabolic process GO:0006518 32 0.011
cell type specific apoptotic process GO:0097285 134 0.011
embryonic pattern specification GO:0009880 1 0.011
single organism biosynthetic process GO:0044711 342 0.011
Human
reactive oxygen species metabolic process GO:0072593 37 0.011
cell cycle GO:0007049 101 0.011
gamete generation GO:0007276 124 0.011
circulatory system process GO:0003013 183 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
regulation of calcium ion transport GO:0051924 77 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
response to temperature stimulus GO:0009266 94 0.011
eye morphogenesis GO:0048592 4 0.011
hexose metabolic process GO:0019318 58 0.011
nuclear transport GO:0051169 49 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
regulation of proteolysis GO:0030162 66 0.011
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.010
Human Mouse
reactive nitrogen species metabolic process GO:2001057 1 0.010
transformation of host cell by virus GO:0019087 4 0.010
response to amino acid GO:0043200 75 0.010
adult locomotory behavior GO:0008344 4 0.010
regulation of growth GO:0040008 105 0.010
organic hydroxy compound transport GO:0015850 77 0.010
Human Mouse
positive regulation of nervous system development GO:0051962 178 0.010
cellular macromolecule catabolic process GO:0044265 29 0.010
positive regulation of secretion GO:0051047 140 0.010
Mouse
defense response to gram negative bacterium GO:0050829 3 0.010
positive regulation of cell development GO:0010720 176 0.010
organ morphogenesis GO:0009887 75 0.010
gliogenesis GO:0042063 93 0.010
growth GO:0040007 165 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
Mouse

Nr1h2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
musculoskeletal system disease DOID:17 0 0.037
disease of metabolism DOID:0014667 0 0.022
nervous system disease DOID:863 0 0.016
connective tissue disease DOID:65 0 0.015
muscular disease DOID:0080000 0 0.015
muscle tissue disease DOID:66 0 0.015
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.013
organ system cancer DOID:0050686 0 0.013
myopathy DOID:423 0 0.012
inherited metabolic disorder DOID:655 0 0.012