Rattus norvegicus

12 known processes

Paics

phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

(Aliases: Airc,Ade2h1,MGC93240)

Paics biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.204
protein complex assembly GO:0006461 263 0.156
nucleic acid templated transcription GO:0097659 379 0.143
response to oxidative stress GO:0006979 186 0.133
lipid metabolic process GO:0006629 283 0.117
cell type specific apoptotic process GO:0097285 134 0.112
regulation of apoptotic process GO:0042981 335 0.105
negative regulation of cell death GO:0060548 229 0.101
protein complex biogenesis GO:0070271 263 0.101
transcription dna templated GO:0006351 377 0.099
central nervous system development GO:0007417 311 0.099
regulation of transcription dna templated GO:0006355 374 0.095
regulation of programmed cell death GO:0043067 341 0.095
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.093
oxoacid metabolic process GO:0043436 290 0.091
rna metabolic process GO:0016070 406 0.090
negative regulation of programmed cell death GO:0043069 183 0.083
head development GO:0060322 247 0.081
programmed cell death GO:0012501 392 0.078
response to inorganic substance GO:0010035 377 0.078
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.074
positive regulation of rna biosynthetic process GO:1902680 197 0.073
regulation of signal transduction GO:0009966 318 0.073
regulation of transforming growth factor beta3 production GO:0032910 2 0.070
cellular amino acid metabolic process GO:0006520 107 0.067
response to molecule of bacterial origin GO:0002237 194 0.065
negative regulation of apoptotic process GO:0043066 181 0.064
regulation of nucleic acid templated transcription GO:1903506 380 0.063
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.062
organophosphate metabolic process GO:0019637 370 0.061
organophosphate biosynthetic process GO:0090407 143 0.061
positive regulation of gene expression GO:0010628 244 0.060
cell projection organization GO:0030030 302 0.059
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.058
purine containing compound biosynthetic process GO:0072522 85 0.056
rhythmic process GO:0048511 156 0.054
apoptotic process GO:0006915 381 0.054
tissue development GO:0009888 252 0.053
positive regulation of biosynthetic process GO:0009891 319 0.050
intracellular signal transduction GO:0035556 314 0.048
neuron death GO:0070997 127 0.048
reproductive process GO:0022414 372 0.048
purine containing compound metabolic process GO:0072521 253 0.048
positive regulation of nucleic acid templated transcription GO:1903508 197 0.047
cellular response to stress GO:0033554 269 0.047
carboxylic acid metabolic process GO:0019752 289 0.047
purine nucleotide biosynthetic process GO:0006164 83 0.047
regulation of rna metabolic process GO:0051252 391 0.047
single organism reproductive process GO:0044702 297 0.047
rna biosynthetic process GO:0032774 380 0.047
regulation of rna biosynthetic process GO:2001141 381 0.046
organic acid metabolic process GO:0006082 292 0.046
neurological system process GO:0050877 219 0.045
organelle organization GO:0006996 266 0.045
neuron differentiation GO:0030182 368 0.045
transcription from rna polymerase ii promoter GO:0006366 252 0.045
regulation of cellular component organization GO:0051128 368 0.045
brain development GO:0007420 247 0.044
protein phosphorylation GO:0006468 345 0.043
nucleotide metabolic process GO:0009117 279 0.043
negative regulation of gene expression GO:0010629 199 0.042
cellular lipid metabolic process GO:0044255 208 0.042
nucleoside phosphate biosynthetic process GO:1901293 102 0.042
positive regulation of cellular biosynthetic process GO:0031328 295 0.042
reproduction GO:0000003 245 0.041
positive regulation of transcription dna templated GO:0045893 197 0.040
single organism organelle organization GO:1902589 180 0.040
cellular response to endogenous stimulus GO:0071495 377 0.039
regulation of catalytic activity GO:0050790 304 0.039
negative regulation of cell communication GO:0010648 158 0.039
positive regulation of cell proliferation GO:0008284 249 0.038
response to hypoxia GO:0001666 231 0.038
nucleobase containing small molecule metabolic process GO:0055086 316 0.038
organonitrogen compound biosynthetic process GO:1901566 167 0.038
cellular homeostasis GO:0019725 252 0.038
response to external biotic stimulus GO:0043207 221 0.037
neuron apoptotic process GO:0051402 88 0.037
response to metal ion GO:0010038 253 0.036
cellular response to oxidative stress GO:0034599 76 0.036
negative regulation of neuron death GO:1901215 69 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.036
cellular component assembly GO:0022607 360 0.036
negative regulation of cellular metabolic process GO:0031324 281 0.036
response to peptide hormone GO:0043434 278 0.035
response to acid chemical GO:0001101 222 0.034
positive regulation of rna metabolic process GO:0051254 203 0.034
macromolecular complex assembly GO:0065003 273 0.034
response to bacterium GO:0009617 200 0.034
response to extracellular stimulus GO:0009991 380 0.033
response to biotic stimulus GO:0009607 226 0.033
macromolecular complex subunit organization GO:0043933 339 0.033
protein complex subunit organization GO:0071822 302 0.033
response to other organism GO:0051707 220 0.032
regulation of cell differentiation GO:0045595 320 0.032
carbohydrate derivative biosynthetic process GO:1901137 124 0.032
ossification GO:0001503 70 0.032
positive regulation of programmed cell death GO:0043068 157 0.032
cellular component biogenesis GO:0044085 368 0.032
negative regulation of signaling GO:0023057 157 0.032
negative regulation of metabolic process GO:0009892 331 0.031
negative regulation of nucleic acid templated transcription GO:1903507 117 0.031
transforming growth factor beta3 production GO:0032907 2 0.030
regulation of molecular function GO:0065009 398 0.030
cell cycle GO:0007049 101 0.030
response to decreased oxygen levels GO:0036293 237 0.029
cation transport GO:0006812 382 0.029
circulatory system process GO:0003013 183 0.029
aging GO:0007568 241 0.029
regulation of neuron apoptotic process GO:0043523 83 0.028
cellular response to hormone stimulus GO:0032870 247 0.028
peptidyl amino acid modification GO:0018193 126 0.028
single organism intracellular transport GO:1902582 166 0.028
negative regulation of neuron apoptotic process GO:0043524 45 0.028
blood circulation GO:0008015 183 0.028
nucleotide biosynthetic process GO:0009165 98 0.028
single organism catabolic process GO:0044712 283 0.027
cellular response to growth factor stimulus GO:0071363 162 0.027
response to peptide GO:1901652 292 0.027
response to wounding GO:0009611 254 0.027
negative regulation of biosynthetic process GO:0009890 168 0.027
cellular amine metabolic process GO:0044106 38 0.027
response to ketone GO:1901654 182 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.026
metal ion transport GO:0030001 289 0.026
organ regeneration GO:0031100 101 0.026
regulation of cellular protein metabolic process GO:0032268 267 0.026
regulation of protein metabolic process GO:0051246 289 0.026
carbohydrate metabolic process GO:0005975 130 0.026
negative regulation of rna biosynthetic process GO:1902679 118 0.026
homeostatic process GO:0042592 331 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
mesoderm development GO:0007498 2 0.025
cellular chemical homeostasis GO:0055082 247 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.024
response to lipopolysaccharide GO:0032496 191 0.024
neuron development GO:0048666 286 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.024
enzyme linked receptor protein signaling pathway GO:0007167 116 0.024
regulation of cell proliferation GO:0042127 359 0.023
positive regulation of transforming growth factor beta3 production GO:0032916 2 0.023
response to nutrient levels GO:0031667 370 0.023
response to alkaloid GO:0043279 132 0.023
neuron projection development GO:0031175 273 0.023
response to oxygen levels GO:0070482 265 0.023
regulation of cell development GO:0060284 263 0.023
osteoblast differentiation GO:0001649 26 0.022
ovulation cycle GO:0042698 67 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
amine metabolic process GO:0009308 38 0.022
positive regulation of protein metabolic process GO:0051247 178 0.022
response to nitrosative stress GO:0051409 2 0.022
regulation of locomotion GO:0040012 148 0.022
positive regulation of developmental process GO:0051094 283 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
dephosphorylation GO:0016311 98 0.022
regulation of neurogenesis GO:0050767 247 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
cellular response to peptide hormone stimulus GO:0071375 120 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
multicellular organism reproduction GO:0032504 233 0.021
response to cytokine GO:0034097 215 0.021
positive regulation of cell death GO:0010942 184 0.021
negative regulation of transcription dna templated GO:0045892 116 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
regulation of membrane potential GO:0042391 110 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
intracellular transport GO:0046907 185 0.020
cofactor metabolic process GO:0051186 95 0.020
negative regulation of rna metabolic process GO:0051253 123 0.020
small molecule catabolic process GO:0044282 59 0.020
cellular catabolic process GO:0044248 295 0.020
ribose phosphate biosynthetic process GO:0046390 87 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
cellular protein localization GO:0034613 122 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
positive regulation of molecular function GO:0044093 230 0.019
chemical homeostasis GO:0048878 292 0.019
purine nucleoside biosynthetic process GO:0042451 21 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
growth GO:0040007 165 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
cytokine production GO:0001816 61 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
positive regulation of signaling GO:0023056 270 0.018
kidney development GO:0001822 67 0.018
organic substance catabolic process GO:1901575 316 0.018
regulation of neuron death GO:1901214 115 0.018
protein processing GO:0016485 68 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
response to growth factor GO:0070848 189 0.018
cellular ketone metabolic process GO:0042180 51 0.018
cellular response to abiotic stimulus GO:0071214 85 0.018
negative regulation of signal transduction GO:0009968 83 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
oxidation reduction process GO:0055114 304 0.018
ion transmembrane transport GO:0034220 365 0.017
positive regulation of hydrolase activity GO:0051345 86 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
monovalent inorganic cation transport GO:0015672 172 0.017
nucleoside monophosphate biosynthetic process GO:0009124 28 0.017
alpha amino acid metabolic process GO:1901605 71 0.017
vesicle mediated transport GO:0016192 181 0.017
response to purine containing compound GO:0014074 126 0.016
negative regulation of intracellular signal transduction GO:1902532 38 0.016
positive regulation of cell communication GO:0010647 271 0.016
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 4 0.016
secretion GO:0046903 307 0.016
ribonucleotide biosynthetic process GO:0009260 85 0.016
mitotic cell cycle process GO:1903047 35 0.016
catabolic process GO:0009056 351 0.016
positive regulation of nervous system development GO:0051962 178 0.016
response to radiation GO:0009314 137 0.016
protein maturation GO:0051604 68 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
cytoskeleton organization GO:0007010 111 0.016
regulation of cell cycle GO:0051726 73 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.015
male sex differentiation GO:0046661 64 0.015
regulation of neuron differentiation GO:0045664 208 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
regulation of cell adhesion GO:0030155 52 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
transmembrane transport GO:0055085 412 0.015
regulation of cell projection organization GO:0031344 175 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.014
regulation of hormone levels GO:0010817 187 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
regulation of cell motility GO:2000145 131 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
protein oligomerization GO:0051259 191 0.014
multi organism reproductive process GO:0044703 262 0.014
single organism membrane organization GO:0044802 74 0.014
cation transmembrane transport GO:0098655 263 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
secretion by cell GO:0032940 248 0.014
regulation of neuron projection development GO:0010975 161 0.014
cell migration GO:0016477 197 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.013
respiratory gaseous exchange GO:0007585 4 0.013
renal system development GO:0072001 67 0.013
response to insulin GO:0032868 133 0.013
cytoplasmic transport GO:0016482 115 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
urogenital system development GO:0001655 78 0.013
regulation of hydrolase activity GO:0051336 143 0.013
regulation of blood pressure GO:0008217 83 0.013
positive regulation of cell development GO:0010720 176 0.013
regeneration GO:0031099 163 0.013
cellular macromolecule localization GO:0070727 122 0.013
cellular response to peptide GO:1901653 133 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
positive regulation of biomineral tissue development GO:0070169 4 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
response to carbohydrate GO:0009743 183 0.013
trna metabolic process GO:0006399 4 0.012
ethanol oxidation GO:0006069 2 0.012
response to glucose GO:0009749 136 0.012
response to monosaccharide GO:0034284 159 0.012
regulation of protein modification process GO:0031399 194 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
locomotion GO:0040011 237 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
regulation of cell migration GO:0030334 128 0.012
regulation of response to external stimulus GO:0032101 106 0.012
intracellular protein transport GO:0006886 79 0.012
protein transport GO:0015031 132 0.011
tetrahydrofolate metabolic process GO:0046653 9 0.011
respiratory system process GO:0003016 3 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
neuronal action potential GO:0019228 35 0.011
toxin transport GO:1901998 3 0.011
cell motility GO:0048870 202 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
regulation of nervous system development GO:0051960 264 0.011
cellular response to lipid GO:0071396 201 0.011
positive regulation of transport GO:0051050 245 0.011
response to vitamin GO:0033273 131 0.011
response to estrogen GO:0043627 232 0.011
response to nutrient GO:0007584 248 0.011
wound healing GO:0042060 122 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
development of primary sexual characteristics GO:0045137 107 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
cation homeostasis GO:0055080 195 0.010
ion homeostasis GO:0050801 212 0.010
mitotic cell cycle GO:0000278 49 0.010
purine ribonucleoside biosynthetic process GO:0046129 21 0.010
bmp signaling pathway GO:0030509 4 0.010
macromolecule localization GO:0033036 252 0.010
positive regulation of signal transduction GO:0009967 175 0.010
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.010

Paics disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013