Rattus norvegicus

0 known processes

Fmr1

fragile X mental retardation 1

(Aliases: FMRP)

Fmr1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.441
transcription dna templated GO:0006351 377 0.216
central nervous system development GO:0007417 311 0.190
Mouse Fly
negative regulation of multicellular organismal process GO:0051241 203 0.156
Fly
nitrogen compound transport GO:0071705 229 0.154
Fly
regulation of cell differentiation GO:0045595 320 0.111
Fly
regulation of transcription dna templated GO:0006355 374 0.101
cellular amino acid metabolic process GO:0006520 107 0.100
protein phosphorylation GO:0006468 345 0.099
organic acid metabolic process GO:0006082 292 0.093
locomotion GO:0040011 237 0.090
Fly
regulation of neuron differentiation GO:0045664 208 0.088
Fly
neuron differentiation GO:0030182 368 0.084
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.084
carboxylic acid metabolic process GO:0019752 289 0.084
brain development GO:0007420 247 0.082
Fly
regulation of cellular ketone metabolic process GO:0010565 27 0.074
transcription from rna polymerase ii promoter GO:0006366 252 0.071
secretion GO:0046903 307 0.065
Fly
regulation of secretion GO:0051046 224 0.061
cellular component biogenesis GO:0044085 368 0.059
Fly
regulation of multicellular organismal development GO:2000026 376 0.058
Fly
anatomical structure morphogenesis GO:0009653 298 0.058
Fly
regulation of homeostatic process GO:0032844 101 0.056
single organism reproductive process GO:0044702 297 0.056
Fly
head development GO:0060322 247 0.055
Fly
rna biosynthetic process GO:0032774 380 0.053
anion transport GO:0006820 178 0.053
action potential GO:0001508 54 0.053
positive regulation of transport GO:0051050 245 0.052
regulation of secretion by cell GO:1903530 208 0.052
inorganic ion transmembrane transport GO:0098660 229 0.051
cellular response to stress GO:0033554 269 0.050
ion transmembrane transport GO:0034220 365 0.050
regulation of molecular function GO:0065009 398 0.047
regulation of phosphorus metabolic process GO:0051174 349 0.047
cell morphogenesis involved in differentiation GO:0000904 119 0.045
Fly
secretion by cell GO:0032940 248 0.045
Fly
positive regulation of homeostatic process GO:0032846 49 0.045
negative regulation of developmental process GO:0051093 125 0.044
Fly
negative regulation of growth GO:0045926 37 0.044
Fly
response to molecule of bacterial origin GO:0002237 194 0.044
cellular lipid metabolic process GO:0044255 208 0.044
single organism catabolic process GO:0044712 283 0.043
actin filament based process GO:0030029 86 0.043
oxoacid metabolic process GO:0043436 290 0.043
organic acid transport GO:0015849 116 0.043
regulation of signal transduction GO:0009966 318 0.042
Fly
carboxylic acid transport GO:0046942 115 0.042
negative regulation of metabolic process GO:0009892 331 0.041
Mouse Fly
regulation of nucleic acid templated transcription GO:1903506 380 0.041
regulation of membrane potential GO:0042391 110 0.041
hormone secretion GO:0046879 115 0.040
immune system development GO:0002520 41 0.040
regulation of nervous system development GO:0051960 264 0.039
Fly
cofactor metabolic process GO:0051186 95 0.039
regulation of cellular localization GO:0060341 263 0.039
amine metabolic process GO:0009308 38 0.039
rna metabolic process GO:0016070 406 0.036
neurological system process GO:0050877 219 0.036
Fly
positive regulation of cellular component organization GO:0051130 200 0.035
regulation of rna biosynthetic process GO:2001141 381 0.034
macromolecule localization GO:0033036 252 0.034
Fly
metal ion transport GO:0030001 289 0.034
negative regulation of signaling GO:0023057 157 0.034
Fly
regulation of phosphate metabolic process GO:0019220 349 0.034
regulation of cell projection organization GO:0031344 175 0.034
Fly
amino acid transport GO:0006865 70 0.033
regulation of system process GO:0044057 208 0.032
Fly
reproductive process GO:0022414 372 0.031
Fly
homeostatic process GO:0042592 331 0.031
positive regulation of cell death GO:0010942 184 0.031
response to external biotic stimulus GO:0043207 221 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
response to mechanical stimulus GO:0009612 134 0.029
Fly
positive regulation of cell motility GO:2000147 97 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
axon ensheathment GO:0008366 40 0.028
organic substance catabolic process GO:1901575 316 0.028
regulation of cellular component organization GO:0051128 368 0.028
Fly
skeletal system development GO:0001501 41 0.028
negative regulation of cell communication GO:0010648 158 0.027
Fly
regulation of cell migration GO:0030334 128 0.027
negative regulation of response to stimulus GO:0048585 155 0.027
Fly
cellular ketone metabolic process GO:0042180 51 0.027
regulation of cell proliferation GO:0042127 359 0.027
Fly
blood circulation GO:0008015 183 0.027
neuron projection development GO:0031175 273 0.026
Fly
regulation of cell development GO:0060284 263 0.026
Fly
cellular component movement GO:0006928 248 0.026
Fly
divalent metal ion transport GO:0070838 132 0.025
positive regulation of secretion GO:0051047 140 0.025
positive regulation of catalytic activity GO:0043085 184 0.025
muscle system process GO:0003012 115 0.025
cell projection organization GO:0030030 302 0.025
Fly
positive regulation of cell proliferation GO:0008284 249 0.025
Fly
actin cytoskeleton organization GO:0030036 73 0.025
synaptic transmission GO:0007268 235 0.024
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
Fly
neuronal action potential GO:0019228 35 0.024
organophosphate metabolic process GO:0019637 370 0.024
cell adhesion GO:0007155 110 0.023
negative regulation of phosphorus metabolic process GO:0010563 80 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
cellular catabolic process GO:0044248 295 0.023
neuron death GO:0070997 127 0.023
cellular amine metabolic process GO:0044106 38 0.023
lipid metabolic process GO:0006629 283 0.023
immune system process GO:0002376 204 0.023
regulation of response to stress GO:0080134 126 0.023
cation transmembrane transport GO:0098655 263 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
circulatory system process GO:0003013 183 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
cellular divalent inorganic cation homeostasis GO:0072503 162 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
single organism biosynthetic process GO:0044711 342 0.022
tissue development GO:0009888 252 0.022
regulation of growth GO:0040008 105 0.021
Fly
multicellular organism reproduction GO:0032504 233 0.021
Fly
neuron development GO:0048666 286 0.021
Fly
multicellular organismal signaling GO:0035637 44 0.021
regulation of rna metabolic process GO:0051252 391 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
single organism carbohydrate metabolic process GO:0044723 118 0.020
carbohydrate metabolic process GO:0005975 130 0.020
programmed cell death GO:0012501 392 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
catabolic process GO:0009056 351 0.020
regulation of catalytic activity GO:0050790 304 0.020
reproductive system development GO:0061458 128 0.019
regulation of cellular response to stress GO:0080135 49 0.019
regulation of neurogenesis GO:0050767 247 0.019
Fly
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
metal ion homeostasis GO:0055065 186 0.019
peptide secretion GO:0002790 86 0.019
negative regulation of neurogenesis GO:0050768 78 0.019
Fly
positive regulation of apoptotic process GO:0043065 154 0.019
macromolecular complex assembly GO:0065003 273 0.019
Fly
tube formation GO:0035148 3 0.018
glycerolipid metabolic process GO:0046486 67 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
Fly
response to ketone GO:1901654 182 0.018
positive regulation of cell development GO:0010720 176 0.018
Fly
thyroid gland development GO:0030878 1 0.018
response to nutrient levels GO:0031667 370 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
Mouse Fly
response to extracellular stimulus GO:0009991 380 0.018
lipid biosynthetic process GO:0008610 128 0.018
camera type eye development GO:0043010 48 0.018
response to bacterium GO:0009617 200 0.018
single organism behavior GO:0044708 130 0.018
Fly
intracellular transport GO:0046907 185 0.017
response to acid chemical GO:0001101 222 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
positive regulation of gene expression GO:0010628 244 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
regulation of protein modification process GO:0031399 194 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
sexual reproduction GO:0019953 148 0.017
Fly
axon development GO:0061564 96 0.016
Fly
transmembrane transport GO:0055085 412 0.016
positive regulation of developmental process GO:0051094 283 0.016
Fly
mesoderm development GO:0007498 2 0.016
nucleic acid templated transcription GO:0097659 379 0.016
morphogenesis of embryonic epithelium GO:0016331 3 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
Fly
response to oxygen levels GO:0070482 265 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
hormone transport GO:0009914 121 0.016
cardiovascular system development GO:0072358 134 0.016
multi organism reproductive process GO:0044703 262 0.015
Fly
regulation of hormone levels GO:0010817 187 0.015
response to purine containing compound GO:0014074 126 0.015
circulatory system development GO:0072359 134 0.015
regulation of muscle system process GO:0090257 79 0.015
alternative mrna splicing via spliceosome GO:0000380 4 0.015
regulation of peptide secretion GO:0002791 82 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
regulation of apoptotic process GO:0042981 335 0.015
cell growth GO:0016049 104 0.015
embryonic placenta development GO:0001892 1 0.015
cellular chemical homeostasis GO:0055082 247 0.015
cation homeostasis GO:0055080 195 0.015
positive regulation of molecular function GO:0044093 230 0.015
cellular component assembly GO:0022607 360 0.014
Fly
positive regulation of biosynthetic process GO:0009891 319 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
lipid transport GO:0006869 61 0.014
positive regulation of signaling GO:0023056 270 0.014
regulation of ion transport GO:0043269 245 0.014
peptidyl amino acid modification GO:0018193 126 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
Fly
cell cell signaling GO:0007267 335 0.014
Fly
ensheathment of neurons GO:0007272 40 0.014
response to other organism GO:0051707 220 0.014
regulation of immune system process GO:0002682 123 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
negative regulation of organ growth GO:0046621 3 0.014
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
Mouse Fly
regulation of cellular catabolic process GO:0031329 101 0.014
cellular macromolecular complex assembly GO:0034622 58 0.014
intracellular signal transduction GO:0035556 314 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
calcium ion transport GO:0006816 131 0.014
generation of precursor metabolites and energy GO:0006091 62 0.013
response to ethanol GO:0045471 162 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
Fly
positive regulation of neurogenesis GO:0050769 165 0.013
Fly
regulation of fat cell differentiation GO:0045598 3 0.013
hematopoietic or lymphoid organ development GO:0048534 36 0.013
epithelial tube formation GO:0072175 3 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
response to radiation GO:0009314 137 0.013
regulation of protein localization GO:0032880 81 0.013
regulation of neuron projection development GO:0010975 161 0.013
Fly
negative regulation of transport GO:0051051 136 0.013
regulation of phosphorylation GO:0042325 248 0.013
divalent inorganic cation transport GO:0072511 134 0.013
neural tube formation GO:0001841 1 0.012
reproduction GO:0000003 245 0.012
Fly
phospholipid metabolic process GO:0006644 61 0.012
epithelium development GO:0060429 96 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
Fly
response to cold GO:0009409 29 0.012
localization of cell GO:0051674 202 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
Fly
negative regulation of nervous system development GO:0051961 79 0.012
Fly
inorganic cation transmembrane transport GO:0098662 202 0.012
cell motility GO:0048870 202 0.012
regulation of hormone secretion GO:0046883 106 0.012
negative regulation of signal transduction GO:0009968 83 0.012
Fly
cellular ion homeostasis GO:0006873 184 0.012
cellular response to acid chemical GO:0071229 75 0.012
apoptotic process GO:0006915 381 0.012
positive regulation of transcription factor import into nucleus GO:0042993 4 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
Mouse Fly
cellular homeostasis GO:0019725 252 0.011
myeloid cell differentiation GO:0030099 22 0.011
response to hypoxia GO:0001666 231 0.011
protein complex assembly GO:0006461 263 0.011
response to glucose GO:0009749 136 0.011
developmental growth GO:0048589 100 0.011
Fly
regulation of catabolic process GO:0009894 113 0.011
protein complex subunit organization GO:0071822 302 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
regulation of endocytosis GO:0030100 42 0.011
ion homeostasis GO:0050801 212 0.011
regulation of neuron death GO:1901214 115 0.011
hemopoiesis GO:0030097 34 0.011
organic anion transport GO:0015711 132 0.011
mapk cascade GO:0000165 140 0.011
response to lipopolysaccharide GO:0032496 191 0.011
negative regulation of hormone secretion GO:0046888 46 0.011
positive regulation of signal transduction GO:0009967 175 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
immune effector process GO:0002252 53 0.011
regulation of locomotion GO:0040012 148 0.011
peptide hormone secretion GO:0030072 84 0.011
jnk cascade GO:0007254 28 0.011
actin filament based movement GO:0030048 16 0.011
positive regulation of fat cell differentiation GO:0045600 2 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
single organism organelle organization GO:1902589 180 0.011
Fly
rna localization GO:0006403 4 0.011
Fly
positive regulation of locomotion GO:0040017 102 0.010
l amino acid transport GO:0015807 21 0.010
learning or memory GO:0007611 90 0.010
Fly
response to alkaloid GO:0043279 132 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
Fly
mitotic spindle organization GO:0007052 2 0.010
multicellular organismal reproductive process GO:0048609 233 0.010
Fly

Fmr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
substance related disorder DOID:303 0 0.204
disease of mental health DOID:150 0 0.204
substance dependence DOID:9973 0 0.010