Rattus norvegicus

0 known processes

Cox6a2

cytochrome c oxidase, subunit VIa, polypeptide 2

(Aliases: COX6AH)

Cox6a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
striated muscle contraction GO:0006941 44 0.353
actin myosin filament sliding GO:0033275 2 0.247
cardiac muscle tissue morphogenesis GO:0055008 1 0.223
cardiac ventricle development GO:0003231 1 0.188
organophosphate metabolic process GO:0019637 370 0.163
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.161
muscle organ morphogenesis GO:0048644 1 0.135
cardiac muscle contraction GO:0060048 27 0.129
heart morphogenesis GO:0003007 3 0.129
muscle filament sliding GO:0030049 2 0.125
blood circulation GO:0008015 183 0.123
response to reactive oxygen species GO:0000302 120 0.121
muscle contraction GO:0006936 88 0.108
carboxylic acid metabolic process GO:0019752 289 0.107
circulatory system process GO:0003013 183 0.100
growth GO:0040007 165 0.100
cellular catabolic process GO:0044248 295 0.100
nucleoside phosphate metabolic process GO:0006753 283 0.096
sarcomere organization GO:0045214 6 0.096
cold acclimation GO:0009631 1 0.095
response to oxidative stress GO:0006979 186 0.094
aromatic compound catabolic process GO:0019439 168 0.092
single organism organelle organization GO:1902589 180 0.092
organelle assembly GO:0070925 22 0.082
response to hydrogen peroxide GO:0042542 89 0.080
muscle system process GO:0003012 115 0.075
purine nucleoside monophosphate catabolic process GO:0009128 55 0.074
reproductive process GO:0022414 372 0.071
purine nucleoside triphosphate catabolic process GO:0009146 122 0.071
cellular component assembly GO:0022607 360 0.070
organic substance catabolic process GO:1901575 316 0.068
glycosyl compound metabolic process GO:1901657 182 0.067
protein complex biogenesis GO:0070271 263 0.065
cell growth GO:0016049 104 0.063
head development GO:0060322 247 0.063
cellular component biogenesis GO:0044085 368 0.061
twitch skeletal muscle contraction GO:0014721 3 0.060
oxoacid metabolic process GO:0043436 290 0.057
slow twitch skeletal muscle fiber contraction GO:0031444 2 0.057
cellular response to oxygen containing compound GO:1901701 386 0.057
heart contraction GO:0060047 57 0.057
response to inorganic substance GO:0010035 377 0.055
cardiac chamber development GO:0003205 1 0.054
cellular component morphogenesis GO:0032989 155 0.052
heart process GO:0003015 57 0.052
tissue development GO:0009888 252 0.051
cardiac myofibril assembly GO:0055003 1 0.050
carbohydrate derivative metabolic process GO:1901135 346 0.050
phthalate metabolic process GO:0018963 8 0.049
organic acid metabolic process GO:0006082 292 0.049
muscle tissue development GO:0060537 58 0.048
atp catabolic process GO:0006200 54 0.048
response to heat GO:0009408 60 0.048
protein complex assembly GO:0006461 263 0.047
voluntary skeletal muscle contraction GO:0003010 3 0.047
single organism catabolic process GO:0044712 283 0.046
myosin filament organization GO:0031033 2 0.046
cardiac cell development GO:0055006 16 0.046
muscle tissue morphogenesis GO:0060415 1 0.045
cellular amino acid metabolic process GO:0006520 107 0.044
response to biotic stimulus GO:0009607 226 0.043
nucleoside catabolic process GO:0009164 126 0.042
striated muscle cell development GO:0055002 26 0.042
response to extracellular stimulus GO:0009991 380 0.041
ribonucleoside catabolic process GO:0042454 126 0.040
regulation of system process GO:0044057 208 0.040
intracellular signal transduction GO:0035556 314 0.040
nucleic acid templated transcription GO:0097659 379 0.040
carboxylic acid transport GO:0046942 115 0.039
cellular response to stress GO:0033554 269 0.039
regulation of rna biosynthetic process GO:2001141 381 0.038
cellular amine metabolic process GO:0044106 38 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.038
purine nucleotide metabolic process GO:0006163 229 0.038
oxidation reduction process GO:0055114 304 0.038
regulation of nucleic acid templated transcription GO:1903506 380 0.037
carbohydrate derivative catabolic process GO:1901136 147 0.037
cellular ketone metabolic process GO:0042180 51 0.037
nucleoside triphosphate catabolic process GO:0009143 123 0.037
cytoskeleton organization GO:0007010 111 0.037
aging GO:0007568 241 0.036
cardiovascular system development GO:0072358 134 0.036
amine metabolic process GO:0009308 38 0.036
catabolic process GO:0009056 351 0.036
response to gamma radiation GO:0010332 24 0.036
negative regulation of metabolic process GO:0009892 331 0.035
response to metal ion GO:0010038 253 0.035
regulation of cell growth GO:0001558 85 0.035
rna metabolic process GO:0016070 406 0.035
anatomical structure formation involved in morphogenesis GO:0048646 83 0.035
regulation of blood circulation GO:1903522 110 0.034
cellular component assembly involved in morphogenesis GO:0010927 17 0.034
axis specification GO:0009798 4 0.033
cardiac muscle cell development GO:0055013 16 0.033
atp metabolic process GO:0046034 72 0.033
negative regulation of heart growth GO:0061117 3 0.032
striated muscle tissue development GO:0014706 58 0.032
ribonucleoside metabolic process GO:0009119 174 0.032
organic hydroxy compound metabolic process GO:1901615 115 0.032
negative regulation of cellular metabolic process GO:0031324 281 0.030
ribonucleoside triphosphate metabolic process GO:0009199 141 0.030
ribonucleoside monophosphate catabolic process GO:0009158 55 0.030
nucleoside metabolic process GO:0009116 179 0.030
anion transport GO:0006820 178 0.030
purine nucleoside catabolic process GO:0006152 124 0.029
ribonucleotide catabolic process GO:0009261 136 0.029
purine containing compound catabolic process GO:0072523 138 0.029
actin filament based process GO:0030029 86 0.029
purine nucleoside metabolic process GO:0042278 169 0.029
nucleoside phosphate catabolic process GO:1901292 140 0.028
organophosphate catabolic process GO:0046434 148 0.028
microtubule polymerization or depolymerization GO:0031109 13 0.028
ribonucleoside monophosphate metabolic process GO:0009161 88 0.028
muscle organ development GO:0007517 50 0.028
actomyosin structure organization GO:0031032 22 0.028
purine ribonucleotide catabolic process GO:0009154 136 0.028
negative regulation of rna biosynthetic process GO:1902679 118 0.027
nucleotide metabolic process GO:0009117 279 0.027
negative regulation of cell death GO:0060548 229 0.027
calcitriol biosynthetic process from calciol GO:0036378 2 0.027
heart development GO:0007507 72 0.027
ribose phosphate metabolic process GO:0019693 235 0.026
nucleoside monophosphate metabolic process GO:0009123 93 0.026
organelle organization GO:0006996 266 0.026
response to estrogen GO:0043627 232 0.026
muscle cell differentiation GO:0042692 52 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
organonitrogen compound catabolic process GO:1901565 179 0.025
purine ribonucleoside metabolic process GO:0046128 168 0.025
regulation of multicellular organismal development GO:2000026 376 0.024
skeletal muscle cell differentiation GO:0035914 2 0.024
response to peptide hormone GO:0043434 278 0.024
multi organism reproductive process GO:0044703 262 0.024
transcription dna templated GO:0006351 377 0.024
nucleoside triphosphate metabolic process GO:0009141 144 0.024
response to estradiol GO:0032355 164 0.024
regulation of atpase activity GO:0043462 7 0.023
response to ionizing radiation GO:0010212 59 0.023
organic anion transport GO:0015711 132 0.023
regulation of growth GO:0040008 105 0.022
response to insulin GO:0032868 133 0.022
embryonic axis specification GO:0000578 1 0.022
cellular response to abiotic stimulus GO:0071214 85 0.022
actin cytoskeleton organization GO:0030036 73 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
forebrain development GO:0030900 98 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
chemical homeostasis GO:0048878 292 0.022
response to mechanical stimulus GO:0009612 134 0.022
cellular ion homeostasis GO:0006873 184 0.022
rna biosynthetic process GO:0032774 380 0.021
response to bacterium GO:0009617 200 0.021
purine containing compound metabolic process GO:0072521 253 0.021
macromolecular complex assembly GO:0065003 273 0.021
nucleotide catabolic process GO:0009166 139 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
ribonucleoside triphosphate catabolic process GO:0009203 122 0.021
neuron development GO:0048666 286 0.020
anterior posterior pattern specification GO:0009952 1 0.020
single organism biosynthetic process GO:0044711 342 0.020
enzyme linked receptor protein signaling pathway GO:0007167 116 0.020
response to external biotic stimulus GO:0043207 221 0.020
cell projection organization GO:0030030 302 0.020
purine nucleoside triphosphate metabolic process GO:0009144 141 0.020
negative regulation of growth GO:0045926 37 0.020
regulation of muscle filament sliding GO:0032971 1 0.020
myofibril assembly GO:0030239 6 0.020
regulation of cellular catabolic process GO:0031329 101 0.020
nucleoside monophosphate catabolic process GO:0009125 56 0.020
glycosyl compound catabolic process GO:1901658 126 0.020
myosin filament assembly GO:0031034 1 0.020
c21 steroid hormone metabolic process GO:0008207 14 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
circulatory system development GO:0072359 134 0.019
regulation of cell development GO:0060284 263 0.019
cardiac muscle tissue development GO:0048738 26 0.018
response to temperature stimulus GO:0009266 94 0.018
homeostatic process GO:0042592 331 0.018
regulation of cellular localization GO:0060341 263 0.018
cation transport GO:0006812 382 0.018
regulation of cellular component organization GO:0051128 368 0.018
purine nucleoside monophosphate metabolic process GO:0009126 84 0.018
protein complex subunit organization GO:0071822 302 0.018
skeletal muscle contraction GO:0003009 17 0.018
embryonic pattern specification GO:0009880 1 0.018
response to nutrient levels GO:0031667 370 0.018
anatomical structure morphogenesis GO:0009653 298 0.017
multicellular organism reproduction GO:0032504 233 0.017
antral ovarian follicle growth GO:0001547 3 0.017
response to acid chemical GO:0001101 222 0.017
dicarboxylic acid metabolic process GO:0043648 42 0.017
regulation of muscle system process GO:0090257 79 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.017
peptide secretion GO:0002790 86 0.017
involuntary skeletal muscle contraction GO:0003011 2 0.017
apoptotic process GO:0006915 381 0.017
ventricular cardiac muscle cell action potential GO:0086005 2 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
regulation of blood pressure GO:0008217 83 0.016
regulation of map kinase activity GO:0043405 53 0.016
single organism reproductive process GO:0044702 297 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
heterocycle catabolic process GO:0046700 167 0.016
regulation of catabolic process GO:0009894 113 0.016
response to oxygen levels GO:0070482 265 0.016
central nervous system development GO:0007417 311 0.016
cardiocyte differentiation GO:0035051 22 0.016
positive regulation of fatty acid beta oxidation GO:0032000 4 0.016
camera type eye development GO:0043010 48 0.015
bmp signaling pathway GO:0030509 4 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
programmed cell death GO:0012501 392 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.015
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.015
secretion GO:0046903 307 0.015
response to calcium ion GO:0051592 59 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
regulation of transcription dna templated GO:0006355 374 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
regulation of signal transduction GO:0009966 318 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
negative regulation of transcription dna templated GO:0045892 116 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
lipid localization GO:0010876 62 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
regulation of neuron differentiation GO:0045664 208 0.014
developmental process involved in reproduction GO:0003006 159 0.014
amide transport GO:0042886 105 0.014
response to vitamin GO:0033273 131 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
regulation of cell differentiation GO:0045595 320 0.014
female pregnancy GO:0007565 122 0.014
diaphragm contraction GO:0002086 2 0.013
sexual reproduction GO:0019953 148 0.013
response to ketone GO:1901654 182 0.013
cellular amino acid biosynthetic process GO:0008652 32 0.013
muscle cell development GO:0055001 26 0.013
defense response GO:0006952 194 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
intracellular transport GO:0046907 185 0.013
regulation of catalytic activity GO:0050790 304 0.013
negative regulation of organ growth GO:0046621 3 0.013
cellular protein complex assembly GO:0043623 44 0.013
cellular macromolecule localization GO:0070727 122 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
muscle structure development GO:0061061 87 0.013
negative regulation of cell growth GO:0030308 33 0.013
cellular component movement GO:0006928 248 0.013
regulation of muscle contraction GO:0006937 53 0.013
monocarboxylic acid biosynthetic process GO:0072330 48 0.013
brain development GO:0007420 247 0.013
skeletal muscle tissue development GO:0007519 31 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.012
nitrogen compound transport GO:0071705 229 0.012
erythrocyte aggregation GO:0034117 1 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
positive regulation of signaling GO:0023056 270 0.012
response to camp GO:0051591 91 0.012
single organism intracellular transport GO:1902582 166 0.012
response to decreased oxygen levels GO:0036293 237 0.012
amino acid transport GO:0006865 70 0.012
dibenzo p dioxin metabolic process GO:0018894 10 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
rna localization GO:0006403 4 0.012
regulation of nervous system development GO:0051960 264 0.012
regulation of rna metabolic process GO:0051252 391 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
maternal process involved in female pregnancy GO:0060135 38 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
regulation of neuron projection development GO:0010975 161 0.012
response to hypoxia GO:0001666 231 0.012
positive regulation of lipid catabolic process GO:0050996 4 0.012
reproduction GO:0000003 245 0.012
lens fiber cell differentiation GO:0070306 3 0.012
positive regulation of transport GO:0051050 245 0.011
erythrocyte differentiation GO:0030218 1 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
single organism carbohydrate catabolic process GO:0044724 40 0.011
regulation of cell proliferation GO:0042127 359 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
fractalkine metabolic process GO:0050756 3 0.011
appendage morphogenesis GO:0035107 4 0.011
axon development GO:0061564 96 0.011
axonogenesis GO:0007409 71 0.011
carbohydrate catabolic process GO:0016052 40 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
cellular protein localization GO:0034613 122 0.011
macromolecule localization GO:0033036 252 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
regulation of cell projection organization GO:0031344 175 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
protein folding GO:0006457 12 0.011
negative regulation of cell growth involved in cardiac muscle cell development GO:0061052 1 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
macromolecular complex subunit organization GO:0043933 339 0.011
negative regulation of cell communication GO:0010648 158 0.010
hematopoietic or lymphoid organ development GO:0048534 36 0.010
immune system process GO:0002376 204 0.010
regulation of molecular function GO:0065009 398 0.010
response to nutrient GO:0007584 248 0.010
stress activated protein kinase signaling cascade GO:0031098 37 0.010
reproductive system development GO:0061458 128 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
cellular cation homeostasis GO:0030003 180 0.010
regulation of programmed cell death GO:0043067 341 0.010
small molecule biosynthetic process GO:0044283 124 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
ribonucleotide metabolic process GO:0009259 231 0.010

Cox6a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.963
muscular disease DOID:0080000 0 0.963
heart disease DOID:114 0 0.963
cardiomyopathy DOID:0050700 0 0.963
disease of anatomical entity DOID:7 0 0.963
intrinsic cardiomyopathy DOID:0060036 0 0.963
cardiovascular system disease DOID:1287 0 0.963
musculoskeletal system disease DOID:17 0 0.963
muscle tissue disease DOID:66 0 0.963
dilated cardiomyopathy DOID:12930 0 0.461
hypertrophic cardiomyopathy DOID:11984 0 0.183
congenital heart disease DOID:1682 0 0.047
heart septal defect DOID:1681 0 0.047
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.023
nervous system disease DOID:863 0 0.013
retinal disease DOID:5679 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011