Rattus norvegicus

133 known processes

Rab4a

RAB4A, member RAS oncogene family

(Aliases: Rab4)

Rab4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.101
protein phosphorylation GO:0006468 345 0.099
oxoacid metabolic process GO:0043436 290 0.083
cell projection organization GO:0030030 302 0.078
single organism biosynthetic process GO:0044711 342 0.076
anatomical structure morphogenesis GO:0009653 298 0.075
cellular response to stress GO:0033554 269 0.075
macromolecular complex subunit organization GO:0043933 339 0.066
organic substance catabolic process GO:1901575 316 0.066
carbohydrate derivative metabolic process GO:1901135 346 0.066
establishment of protein localization GO:0045184 141 0.066
Mouse
neuron development GO:0048666 286 0.059
nucleobase containing small molecule metabolic process GO:0055086 316 0.058
organophosphate biosynthetic process GO:0090407 143 0.056
protein localization GO:0008104 191 0.056
Mouse Rat
organophosphate metabolic process GO:0019637 370 0.056
regulation of cellular protein metabolic process GO:0032268 267 0.053
regulation of phosphate metabolic process GO:0019220 349 0.053
catabolic process GO:0009056 351 0.053
regulation of phosphorus metabolic process GO:0051174 349 0.052
carboxylic acid metabolic process GO:0019752 289 0.051
regulation of signal transduction GO:0009966 318 0.051
positive regulation of developmental process GO:0051094 283 0.050
glycosyl compound metabolic process GO:1901657 182 0.049
response to wounding GO:0009611 254 0.049
purine containing compound metabolic process GO:0072521 253 0.048
neuron differentiation GO:0030182 368 0.048
macromolecule localization GO:0033036 252 0.048
Mouse Rat
negative regulation of cellular metabolic process GO:0031324 281 0.044
single organism catabolic process GO:0044712 283 0.044
carbohydrate metabolic process GO:0005975 130 0.044
transmembrane transport GO:0055085 412 0.044
rna biosynthetic process GO:0032774 380 0.043
regulation of protein phosphorylation GO:0001932 183 0.043
regulation of molecular function GO:0065009 398 0.043
regulation of cell differentiation GO:0045595 320 0.042
cellular protein localization GO:0034613 122 0.042
nucleoside phosphate metabolic process GO:0006753 283 0.041
cellular catabolic process GO:0044248 295 0.040
transcription dna templated GO:0006351 377 0.040
positive regulation of phosphorus metabolic process GO:0010562 262 0.039
cell cell signaling GO:0007267 335 0.038
regulation of cell development GO:0060284 263 0.038
organic acid metabolic process GO:0006082 292 0.037
positive regulation of cell differentiation GO:0045597 217 0.036
cellular amine metabolic process GO:0044106 38 0.036
cation transport GO:0006812 382 0.035
regulation of catalytic activity GO:0050790 304 0.035
regulation of nervous system development GO:0051960 264 0.035
regulation of protein metabolic process GO:0051246 289 0.035
multicellular organism growth GO:0035264 1 0.035
regulation of catabolic process GO:0009894 113 0.035
organic cyclic compound catabolic process GO:1901361 175 0.035
organelle organization GO:0006996 266 0.034
regulation of cellular localization GO:0060341 263 0.034
positive regulation of biosynthetic process GO:0009891 319 0.033
positive regulation of signaling GO:0023056 270 0.033
aging GO:0007568 241 0.033
cellular component biogenesis GO:0044085 368 0.032
vesicle mediated transport GO:0016192 181 0.032
Mouse
single organism intracellular transport GO:1902582 166 0.032
regulation of cell projection organization GO:0031344 175 0.032
intracellular transport GO:0046907 185 0.031
enzyme linked receptor protein signaling pathway GO:0007167 116 0.031
central nervous system development GO:0007417 311 0.031
response to growth factor GO:0070848 189 0.031
dephosphorylation GO:0016311 98 0.031
nucleoside metabolic process GO:0009116 179 0.030
negative regulation of metabolic process GO:0009892 331 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
positive regulation of protein phosphorylation GO:0001934 135 0.030
synaptic transmission GO:0007268 235 0.030
ribonucleotide metabolic process GO:0009259 231 0.030
regulation of kinase activity GO:0043549 117 0.030
nucleotide metabolic process GO:0009117 279 0.029
purine nucleotide metabolic process GO:0006163 229 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
nitrogen compound transport GO:0071705 229 0.029
positive regulation of monooxygenase activity GO:0032770 5 0.029
regulation of rna metabolic process GO:0051252 391 0.029
nucleic acid templated transcription GO:0097659 379 0.029
ion transmembrane transport GO:0034220 365 0.029
positive regulation of cell development GO:0010720 176 0.029
negative regulation of signaling GO:0023057 157 0.029
positive regulation of protein metabolic process GO:0051247 178 0.028
positive regulation of protein modification process GO:0031401 142 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
heterocycle catabolic process GO:0046700 167 0.028
regulation of hydrolase activity GO:0051336 143 0.028
ribose phosphate metabolic process GO:0019693 235 0.028
multi organism reproductive process GO:0044703 262 0.028
cellular ketone metabolic process GO:0042180 51 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
neuron projection development GO:0031175 273 0.027
purine ribonucleoside metabolic process GO:0046128 168 0.027
protein complex subunit organization GO:0071822 302 0.027
signal transduction by phosphorylation GO:0023014 144 0.027
lipid metabolic process GO:0006629 283 0.027
small gtpase mediated signal transduction GO:0007264 36 0.027
reproduction GO:0000003 245 0.027
regulation of protein localization GO:0032880 81 0.027
Rat
regulation of phosphorylation GO:0042325 248 0.027
regulation of transcription dna templated GO:0006355 374 0.026
intracellular protein transport GO:0006886 79 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
regulation of protein modification process GO:0031399 194 0.026
regulation of intracellular signal transduction GO:1902531 218 0.026
single organism organelle organization GO:1902589 180 0.026
cellular component assembly GO:0022607 360 0.026
cell morphogenesis involved in differentiation GO:0000904 119 0.026
ribonucleoside triphosphate catabolic process GO:0009203 122 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
regulation of neurogenesis GO:0050767 247 0.025
cellular nitrogen compound catabolic process GO:0044270 163 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
protein targeting GO:0006605 61 0.024
regulation of nitric oxide synthase activity GO:0050999 8 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
regulation of cellular component organization GO:0051128 368 0.024
Mouse
regulation of growth GO:0040008 105 0.024
regulation of cellular response to stress GO:0080135 49 0.024
regulation of purine nucleotide metabolic process GO:1900542 115 0.023
negative regulation of phosphate metabolic process GO:0045936 80 0.023
amine metabolic process GO:0009308 38 0.023
response to ketone GO:1901654 182 0.023
gtp catabolic process GO:0006184 71 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
glycosyl compound catabolic process GO:1901658 126 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
cellular component morphogenesis GO:0032989 155 0.022
positive regulation of cell communication GO:0010647 271 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
gastrulation GO:0007369 2 0.022
regulation of apoptotic process GO:0042981 335 0.022
cellular macromolecule localization GO:0070727 122 0.022
aromatic compound catabolic process GO:0019439 168 0.022
brain development GO:0007420 247 0.022
jnk cascade GO:0007254 28 0.022
cell morphogenesis GO:0000902 142 0.022
protein transport GO:0015031 132 0.022
Mouse
ribonucleoside metabolic process GO:0009119 174 0.021
single organism carbohydrate metabolic process GO:0044723 118 0.021
regulation of synaptic transmission GO:0050804 141 0.021
positive regulation of catabolic process GO:0009896 78 0.021
regulation of response to external stimulus GO:0032101 106 0.021
ribonucleoside catabolic process GO:0042454 126 0.021
regulation of transferase activity GO:0051338 123 0.021
regulation of organelle organization GO:0033043 80 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
locomotion GO:0040011 237 0.021
secretion by cell GO:0032940 248 0.021
nucleotide catabolic process GO:0009166 139 0.021
cellular response to growth factor stimulus GO:0071363 162 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
negative regulation of cell communication GO:0010648 158 0.020
cytoskeleton organization GO:0007010 111 0.020
purine containing compound catabolic process GO:0072523 138 0.020
neuron death GO:0070997 127 0.020
amide transport GO:0042886 105 0.020
ras protein signal transduction GO:0007265 29 0.020
cellular homeostasis GO:0019725 252 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
regulation of protein kinase activity GO:0045859 105 0.020
protein complex assembly GO:0006461 263 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
gliogenesis GO:0042063 93 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
macromolecular complex assembly GO:0065003 273 0.019
negative regulation of catalytic activity GO:0043086 103 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
regulation of cellular catabolic process GO:0031329 101 0.019
negative regulation of response to nutrient levels GO:0032108 7 0.019
cytoplasmic transport GO:0016482 115 0.019
protein autophosphorylation GO:0046777 66 0.019
organophosphate catabolic process GO:0046434 148 0.019
regulation of peptide transport GO:0090087 87 0.019
negative regulation of phosphorus metabolic process GO:0010563 80 0.019
positive regulation of transport GO:0051050 245 0.019
positive regulation of rna metabolic process GO:0051254 203 0.018
negative regulation of cell differentiation GO:0045596 99 0.018
regulation of secretion GO:0051046 224 0.018
small molecule catabolic process GO:0044282 59 0.018
single organism cellular localization GO:1902580 102 0.018
regulation of locomotion GO:0040012 148 0.018
regulation of ras protein signal transduction GO:0046578 45 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
negative regulation of molecular function GO:0044092 133 0.018
regulation of ion transport GO:0043269 245 0.018
positive regulation of neuron differentiation GO:0045666 126 0.017
response to nutrient levels GO:0031667 370 0.017
axon development GO:0061564 96 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
purine nucleotide catabolic process GO:0006195 136 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
positive regulation of nervous system development GO:0051962 178 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
gtp metabolic process GO:0046039 72 0.017
regulation of cell motility GO:2000145 131 0.017
respiratory system process GO:0003016 3 0.017
response to extracellular stimulus GO:0009991 380 0.017
positive regulation of cellular catabolic process GO:0031331 71 0.017
cell growth GO:0016049 104 0.016
cellular response to endogenous stimulus GO:0071495 377 0.016
protein complex biogenesis GO:0070271 263 0.016
ribose phosphate biosynthetic process GO:0046390 87 0.016
homeostatic process GO:0042592 331 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
regulation of secretion by cell GO:1903530 208 0.016
cell projection morphogenesis GO:0048858 123 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
regulation of anatomical structure size GO:0090066 135 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
regulation of synaptic plasticity GO:0048167 70 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
response to corticosteroid GO:0031960 235 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
establishment of protein localization to organelle GO:0072594 44 0.015
regulation of dendrite development GO:0050773 59 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
head development GO:0060322 247 0.015
response to metal ion GO:0010038 253 0.015
rna metabolic process GO:0016070 406 0.015
regulation of neuron differentiation GO:0045664 208 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
mapk cascade GO:0000165 140 0.015
guanosine containing compound metabolic process GO:1901068 74 0.015
secretion GO:0046903 307 0.015
Rat
purine nucleotide biosynthetic process GO:0006164 83 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
metal ion transport GO:0030001 289 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
phospholipid metabolic process GO:0006644 61 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
regulation of ion transmembrane transport GO:0034765 121 0.014
positive regulation of nucleotide metabolic process GO:0045981 91 0.014
positive regulation of molecular function GO:0044093 230 0.014
signal release GO:0023061 145 0.014
multicellular organism reproduction GO:0032504 233 0.014
regulation of cell proliferation GO:0042127 359 0.014
response to cytokine GO:0034097 215 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
nuclear transport GO:0051169 49 0.014
cellular component movement GO:0006928 248 0.014
regulation of neuron projection development GO:0010975 161 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
autophagy GO:0006914 19 0.014
regulation of programmed cell death GO:0043067 341 0.014
positive regulation of nucleoside metabolic process GO:0045979 55 0.014
behavior GO:0007610 205 0.014
chromosome segregation GO:0007059 2 0.014
inorganic ion transmembrane transport GO:0098660 229 0.013
actin cytoskeleton organization GO:0030036 73 0.013
cell cycle GO:0007049 101 0.013
protein localization to membrane GO:0072657 36 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
sexual reproduction GO:0019953 148 0.013
regulation of cellular component size GO:0032535 51 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
single organism reproductive process GO:0044702 297 0.013
cell fate determination GO:0001709 2 0.013
macroautophagy GO:0016236 4 0.013
hormone secretion GO:0046879 115 0.013
negative regulation of gene expression GO:0010629 199 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
tube development GO:0035295 89 0.013
energy derivation by oxidation of organic compounds GO:0015980 46 0.013
spermatogenesis GO:0007283 99 0.013
cellular chemical homeostasis GO:0055082 247 0.013
regulation of protein transport GO:0051223 68 0.013
protein oligomerization GO:0051259 191 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
lipid biosynthetic process GO:0008610 128 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
peptide transport GO:0015833 97 0.012
response to nutrient GO:0007584 248 0.012
axonogenesis GO:0007409 71 0.012
regulation of immune system process GO:0002682 123 0.012
oxidation reduction process GO:0055114 304 0.012
negative regulation of cell death GO:0060548 229 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
positive regulation of cell death GO:0010942 184 0.012
dna metabolic process GO:0006259 96 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.012
mesoderm development GO:0007498 2 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
cellular response to external stimulus GO:0071496 118 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
positive regulation of secretion GO:0051047 140 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
negative regulation of stress activated mapk cascade GO:0032873 4 0.012
positive regulation of signal transduction GO:0009967 175 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
response to inorganic substance GO:0010035 377 0.012
response to carbohydrate GO:0009743 183 0.012
regulation of map kinase activity GO:0043405 53 0.012
cellular lipid metabolic process GO:0044255 208 0.012
response to hexose GO:0009746 144 0.012
regulation of monooxygenase activity GO:0032768 8 0.012
proteolysis GO:0006508 175 0.012
cation transmembrane transport GO:0098655 263 0.012
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of response to stress GO:0080134 126 0.011
response to glucose GO:0009749 136 0.011
negative regulation of transport GO:0051051 136 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
peptide secretion GO:0002790 86 0.011
regulation of mapk cascade GO:0043408 116 0.011
localization of cell GO:0051674 202 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
regulation of camp metabolic process GO:0030814 43 0.011
cell motility GO:0048870 202 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
regulation of peptide secretion GO:0002791 82 0.011
response to radiation GO:0009314 137 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
eye development GO:0001654 50 0.011
negative regulation of developmental process GO:0051093 125 0.011
respiratory gaseous exchange GO:0007585 4 0.011
erbb signaling pathway GO:0038127 23 0.011
regulation of cyclase activity GO:0031279 21 0.011
regulation of transmembrane transport GO:0034762 122 0.011
regulation of intracellular transport GO:0032386 65 0.011
membrane organization GO:0061024 94 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.010
exocytosis GO:0006887 60 0.010
peptide hormone secretion GO:0030072 84 0.010
regulation of protein serine threonine kinase activity GO:0071900 64 0.010
regulation of hormone levels GO:0010817 187 0.010
positive regulation of rna biosynthetic process GO:1902680 197 0.010
protein heterooligomerization GO:0051291 89 0.010
response to monosaccharide GO:0034284 159 0.010
negative regulation of growth GO:0045926 37 0.010
response to glucocorticoid GO:0051384 223 0.010
growth GO:0040007 165 0.010
ribonucleotide biosynthetic process GO:0009260 85 0.010
biological adhesion GO:0022610 110 0.010
neuron projection morphogenesis GO:0048812 122 0.010
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
axon cargo transport GO:0008088 1 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
regulation of cell growth GO:0001558 85 0.010
regulation of oxidoreductase activity GO:0051341 11 0.010
metal ion homeostasis GO:0055065 186 0.010
hormone transport GO:0009914 121 0.010
regulation of transmembrane transporter activity GO:0022898 49 0.010
response to acid chemical GO:0001101 222 0.010
transcription from rna polymerase ii promoter GO:0006366 252 0.010
single organism membrane organization GO:0044802 74 0.010

Rab4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
disease of metabolism DOID:0014667 0 0.013