Rattus norvegicus

19 known processes

Cdkn2c

cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)

(Aliases: p18)

Cdkn2c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of metabolic process GO:0009892 331 0.068
regulation of multicellular organismal development GO:2000026 376 0.063
nucleotide metabolic process GO:0009117 279 0.057
rna metabolic process GO:0016070 406 0.055
programmed cell death GO:0012501 392 0.055
regulation of rna metabolic process GO:0051252 391 0.051
nucleobase containing small molecule metabolic process GO:0055086 316 0.048
positive regulation of developmental process GO:0051094 283 0.046
negative regulation of cellular metabolic process GO:0031324 281 0.041
organic cyclic compound catabolic process GO:1901361 175 0.041
nucleoside phosphate metabolic process GO:0006753 283 0.039
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
regulation of rna biosynthetic process GO:2001141 381 0.036
cell cycle checkpoint GO:0000075 2 0.035
regulation of nucleic acid templated transcription GO:1903506 380 0.035
organophosphate metabolic process GO:0019637 370 0.035
negative regulation of cell death GO:0060548 229 0.034
regulation of cellular component organization GO:0051128 368 0.033
regulation of transcription dna templated GO:0006355 374 0.032
cellular response to oxygen containing compound GO:1901701 386 0.031
response to peptide hormone GO:0043434 278 0.030
regulation of apoptotic process GO:0042981 335 0.030
regulation of cell differentiation GO:0045595 320 0.030
multi organism reproductive process GO:0044703 262 0.029
regulation of programmed cell death GO:0043067 341 0.029
cellular response to stress GO:0033554 269 0.029
cellular catabolic process GO:0044248 295 0.029
positive regulation of gene expression GO:0010628 244 0.028
apoptotic process GO:0006915 381 0.028
organophosphate catabolic process GO:0046434 148 0.028
negative regulation of gene expression GO:0010629 199 0.027
central nervous system development GO:0007417 311 0.027
purine nucleotide metabolic process GO:0006163 229 0.027
regulation of molecular function GO:0065009 398 0.027
circulatory system development GO:0072359 134 0.027
transcription dna templated GO:0006351 377 0.026
regulation of cellular localization GO:0060341 263 0.026
organic substance catabolic process GO:1901575 316 0.026
vesicle mediated transport GO:0016192 181 0.025
organonitrogen compound catabolic process GO:1901565 179 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
rna biosynthetic process GO:0032774 380 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
cellular nitrogen compound catabolic process GO:0044270 163 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
response to nutrient levels GO:0031667 370 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
chromosome segregation GO:0007059 2 0.023
secretion by cell GO:0032940 248 0.023
ribose phosphate metabolic process GO:0019693 235 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
purine containing compound metabolic process GO:0072521 253 0.022
neuron differentiation GO:0030182 368 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
negative regulation of programmed cell death GO:0043069 183 0.021
cellular response to lipid GO:0071396 201 0.021
cellular protein localization GO:0034613 122 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
single organism catabolic process GO:0044712 283 0.021
positive regulation of cell death GO:0010942 184 0.021
multicellular organism reproduction GO:0032504 233 0.020
nucleic acid templated transcription GO:0097659 379 0.020
protein localization GO:0008104 191 0.020
single organism reproductive process GO:0044702 297 0.020
reproductive process GO:0022414 372 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
regulation of cell proliferation GO:0042127 359 0.019
macromolecule localization GO:0033036 252 0.019
gamete generation GO:0007276 124 0.019
aging GO:0007568 241 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
regulation of neurogenesis GO:0050767 247 0.019
heterocycle catabolic process GO:0046700 167 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
negative regulation of signaling GO:0023057 157 0.018
organelle organization GO:0006996 266 0.018
response to extracellular stimulus GO:0009991 380 0.018
positive regulation of multicellular organismal process GO:0051240 387 0.018
regulation of catabolic process GO:0009894 113 0.018
cardiovascular system development GO:0072358 134 0.018
cellular component biogenesis GO:0044085 368 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
response to peptide GO:1901652 292 0.017
regulation of catalytic activity GO:0050790 304 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
response to inorganic substance GO:0010035 377 0.016
response to decreased oxygen levels GO:0036293 237 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
cellular macromolecule localization GO:0070727 122 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
response to hypoxia GO:0001666 231 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
reproduction GO:0000003 245 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
single organism cellular localization GO:1902580 102 0.015
catabolic process GO:0009056 351 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
regulation of proteasomal protein catabolic process GO:0061136 4 0.015
brain development GO:0007420 247 0.015
single organism biosynthetic process GO:0044711 342 0.015
regulation of secretion by cell GO:1903530 208 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
chemical homeostasis GO:0048878 292 0.014
cellular chemical homeostasis GO:0055082 247 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
cell projection organization GO:0030030 302 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
head development GO:0060322 247 0.014
neuron death GO:0070997 127 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
cellular amine metabolic process GO:0044106 38 0.014
negative regulation of cell communication GO:0010648 158 0.014
secretion GO:0046903 307 0.014
response to temperature stimulus GO:0009266 94 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
mitotic sister chromatid segregation GO:0000070 1 0.014
regeneration GO:0031099 163 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
growth GO:0040007 165 0.013
response to acid chemical GO:0001101 222 0.013
negative regulation of cell cycle phase transition GO:1901988 4 0.013
cellular response to insulin stimulus GO:0032869 81 0.013
regulation of cell projection organization GO:0031344 175 0.013
aromatic compound catabolic process GO:0019439 168 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
regulation of neuron differentiation GO:0045664 208 0.013
nucleoside metabolic process GO:0009116 179 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
cellular homeostasis GO:0019725 252 0.013
neuron projection development GO:0031175 273 0.013
organic acid metabolic process GO:0006082 292 0.013
positive regulation of nervous system development GO:0051962 178 0.012
tissue development GO:0009888 252 0.012
cell cycle GO:0007049 101 0.012
response to insulin GO:0032868 133 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
mitotic cell cycle checkpoint GO:0007093 1 0.012
response to oxygen levels GO:0070482 265 0.012
cell cell signaling GO:0007267 335 0.012
homeostatic process GO:0042592 331 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
synaptic transmission GO:0007268 235 0.012
amine metabolic process GO:0009308 38 0.012
regulation of protein metabolic process GO:0051246 289 0.012
response to nutrient GO:0007584 248 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
meiotic cell cycle process GO:1903046 3 0.012
spermatogenesis GO:0007283 99 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
proteolysis GO:0006508 175 0.011
response to metal ion GO:0010038 253 0.011
regulation of hormone secretion GO:0046883 106 0.011
cellular ketone metabolic process GO:0042180 51 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
dna packaging GO:0006323 4 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
cellular component assembly GO:0022607 360 0.011
cellular component movement GO:0006928 248 0.011
regulation of synaptic transmission GO:0050804 141 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
intracellular transport GO:0046907 185 0.011
regulation of nervous system development GO:0051960 264 0.011
cellular response to peptide GO:1901653 133 0.011
developmental process involved in reproduction GO:0003006 159 0.011
neuron development GO:0048666 286 0.011
nucleoside catabolic process GO:0009164 126 0.011
cellular amino acid metabolic process GO:0006520 107 0.011
positive regulation of cell development GO:0010720 176 0.011
cellular component morphogenesis GO:0032989 155 0.010
regulation of dna metabolic process GO:0051052 60 0.010
protein complex biogenesis GO:0070271 263 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
positive regulation of transport GO:0051050 245 0.010
response to ketone GO:1901654 182 0.010
nucleotide catabolic process GO:0009166 139 0.010
male gamete generation GO:0048232 99 0.010
positive regulation of molecular function GO:0044093 230 0.010
axis specification GO:0009798 4 0.010
nitrogen compound transport GO:0071705 229 0.010
protein phosphorylation GO:0006468 345 0.010

Cdkn2c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
sensory system disease DOID:0050155 0 0.010