Rattus norvegicus

197 known processes

Klf4

Kruppel-like factor 4 (gut)

(Aliases: GKLF,MGC93286)

Klf4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of programmed cell death GO:0043067 341 0.724
Human
regulation of apoptotic process GO:0042981 335 0.723
Human
inactivation of mapk activity GO:0000188 2 0.633
programmed cell death GO:0012501 392 0.604
Human
response to hydrogen peroxide GO:0042542 89 0.532
conditioned taste aversion GO:0001661 2 0.524
positive regulation of myeloid leukocyte differentiation GO:0002763 7 0.512
response to inorganic substance GO:0010035 377 0.511
apoptotic process GO:0006915 381 0.497
Human
positive regulation of programmed cell death GO:0043068 157 0.491
negative regulation of cell death GO:0060548 229 0.475
Human
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.467
positive regulation of apoptotic process GO:0043065 154 0.459
transcription dna templated GO:0006351 377 0.423
negative regulation of biosynthetic process GO:0009890 168 0.415
cellular response to stress GO:0033554 269 0.403
negative regulation of apoptotic process GO:0043066 181 0.382
Human
regulation of nucleic acid templated transcription GO:1903506 380 0.370
negative regulation of cellular biosynthetic process GO:0031327 161 0.369
response to cycloheximide GO:0046898 6 0.359
regulation of transcription dna templated GO:0006355 374 0.357
response to peptide GO:1901652 292 0.341
mapk cascade GO:0000165 140 0.341
positive regulation of cell death GO:0010942 184 0.339
regulation of molecular function GO:0065009 398 0.332
response to cytokine GO:0034097 215 0.318
Human
regulation of rna metabolic process GO:0051252 391 0.316
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.315
Human
neurological system process GO:0050877 219 0.313
regulation of cell proliferation GO:0042127 359 0.310
negative regulation of programmed cell death GO:0043069 183 0.304
Human
negative regulation of cellular metabolic process GO:0031324 281 0.295
cellular response to organic cyclic compound GO:0071407 202 0.295
regulation of rna biosynthetic process GO:2001141 381 0.288
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.277
regulation of phosphorus metabolic process GO:0051174 349 0.274
regulation of multicellular organismal development GO:2000026 376 0.272
Human
response to camp GO:0051591 91 0.267
intracellular signal transduction GO:0035556 314 0.263
rna metabolic process GO:0016070 406 0.262
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.260
rna biosynthetic process GO:0032774 380 0.251
regulation of cellular protein metabolic process GO:0032268 267 0.249
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.248
positive regulation of neuron apoptotic process GO:0043525 33 0.248
regulation of signal transduction GO:0009966 318 0.246
regulation of phosphate metabolic process GO:0019220 349 0.246
nucleic acid templated transcription GO:0097659 379 0.240
response to organophosphorus GO:0046683 102 0.239
transcription from rna polymerase ii promoter GO:0006366 252 0.230
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.227
regulation of phosphorylation GO:0042325 248 0.226
carbohydrate derivative metabolic process GO:1901135 346 0.219
response to wounding GO:0009611 254 0.217
negative regulation of rna biosynthetic process GO:1902679 118 0.217
skeletal muscle cell differentiation GO:0035914 2 0.215
positive regulation of leukocyte differentiation GO:1902107 13 0.211
circadian rhythm GO:0007623 88 0.210
response to purine containing compound GO:0014074 126 0.202
neuron apoptotic process GO:0051402 88 0.199
negative regulation of metabolic process GO:0009892 331 0.198
response to molecule of bacterial origin GO:0002237 194 0.196
regulation of intracellular signal transduction GO:1902531 218 0.194
response to oxidative stress GO:0006979 186 0.192
tissue development GO:0009888 252 0.192
response to corticosteroid GO:0031960 235 0.190
cellular response to endogenous stimulus GO:0071495 377 0.190
nucleobase containing compound catabolic process GO:0034655 152 0.189
cellular response to reactive oxygen species GO:0034614 55 0.185
negative regulation of gene expression GO:0010629 199 0.183
cellular response to oxygen containing compound GO:1901701 386 0.177
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.174
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.172
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.170
regulation of catalytic activity GO:0050790 304 0.168
response to radiation GO:0009314 137 0.167
collateral sprouting GO:0048668 2 0.164
purine nucleoside triphosphate catabolic process GO:0009146 122 0.160
response to metal ion GO:0010038 253 0.154
negative regulation of rna metabolic process GO:0051253 123 0.152
cellular response to interleukin 1 GO:0071347 37 0.147
regulation of neuron apoptotic process GO:0043523 83 0.144
negative regulation of transcription dna templated GO:0045892 116 0.144
circulatory system development GO:0072359 134 0.142
Human
wound healing GO:0042060 122 0.139
neuron differentiation GO:0030182 368 0.135
purine ribonucleotide catabolic process GO:0009154 136 0.134
neuron death GO:0070997 127 0.128
positive regulation of biosynthetic process GO:0009891 319 0.128
response to glucocorticoid GO:0051384 223 0.128
purine nucleotide catabolic process GO:0006195 136 0.125
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.120
positive regulation of gene expression GO:0010628 244 0.119
cellular response to cytokine stimulus GO:0071345 127 0.118
cellular response to organonitrogen compound GO:0071417 197 0.117
localization of cell GO:0051674 202 0.117
Human
positive regulation of multicellular organismal process GO:0051240 387 0.115
response to lipopolysaccharide GO:0032496 191 0.115
regulation of protein metabolic process GO:0051246 289 0.115
Human
cellular response to fluid shear stress GO:0071498 4 0.114
Human
reproductive process GO:0022414 372 0.113
response to laminar fluid shear stress GO:0034616 9 0.112
Human
organic substance catabolic process GO:1901575 316 0.111
blood vessel development GO:0001568 69 0.110
Human
myeloid leukocyte differentiation GO:0002573 20 0.110
negative regulation of cell differentiation GO:0045596 99 0.108
positive regulation of myeloid cell differentiation GO:0045639 7 0.107
response to calcium ion GO:0051592 59 0.106
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.105
cellular response to follicle stimulating hormone stimulus GO:0071372 13 0.102
cytokine mediated signaling pathway GO:0019221 43 0.101
blood vessel morphogenesis GO:0048514 58 0.101
Human
negative regulation of protein metabolic process GO:0051248 114 0.099
Human
immune system process GO:0002376 204 0.099
Human
response to reactive oxygen species GO:0000302 120 0.099
positive regulation of rna metabolic process GO:0051254 203 0.099
cardiovascular system development GO:0072358 134 0.098
Human
response to ketone GO:1901654 182 0.098
positive regulation of transcription dna templated GO:0045893 197 0.098
aromatic compound catabolic process GO:0019439 168 0.097
negative regulation of signaling GO:0023057 157 0.097
negative regulation of neuron apoptotic process GO:0043524 45 0.097
nucleoside phosphate catabolic process GO:1901292 140 0.096
learning or memory GO:0007611 90 0.096
organophosphate metabolic process GO:0019637 370 0.095
multicellular organism reproduction GO:0032504 233 0.094
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.093
behavior GO:0007610 205 0.093
regulation of leukocyte differentiation GO:1902105 20 0.093
response to toxic substance GO:0009636 133 0.092
cellular response to peptide GO:1901653 133 0.090
synaptic growth at neuromuscular junction GO:0051124 1 0.088
negative regulation of multicellular organismal process GO:0051241 203 0.088
cellular response to hormone stimulus GO:0032870 247 0.087
ribonucleoside metabolic process GO:0009119 174 0.087
purine nucleotide metabolic process GO:0006163 229 0.087
cellular response to acid chemical GO:0071229 75 0.086
ribonucleoside catabolic process GO:0042454 126 0.086
central nervous system development GO:0007417 311 0.085
regulation of neurogenesis GO:0050767 247 0.085
chemotaxis GO:0006935 66 0.085
myeloid cell differentiation GO:0030099 22 0.083
negative regulation of mapk cascade GO:0043409 20 0.082
negative regulation of cell proliferation GO:0008285 119 0.082
negative regulation of cellular protein metabolic process GO:0032269 106 0.080
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.080
positive regulation of cellular biosynthetic process GO:0031328 295 0.079
response to alkaloid GO:0043279 132 0.079
regulation of myeloid cell differentiation GO:0045637 12 0.077
cellular catabolic process GO:0044248 295 0.077
negative regulation of phosphorus metabolic process GO:0010563 80 0.076
regulation of viral transcription GO:0046782 2 0.076
regulation of cell development GO:0060284 263 0.076
positive regulation of signaling GO:0023056 270 0.075
positive regulation of nucleic acid templated transcription GO:1903508 197 0.075
glial cell differentiation GO:0010001 65 0.074
purine ribonucleoside metabolic process GO:0046128 168 0.073
positive regulation of neuron death GO:1901216 43 0.073
cell projection organization GO:0030030 302 0.073
bmp signaling pathway GO:0030509 4 0.073
anatomical structure morphogenesis GO:0009653 298 0.072
Human
response to ammonium ion GO:0060359 71 0.072
cognition GO:0050890 92 0.071
regulation of myeloid leukocyte differentiation GO:0002761 12 0.071
hematopoietic or lymphoid organ development GO:0048534 36 0.069
Human
response to hypoxia GO:0001666 231 0.069
response to ionizing radiation GO:0010212 59 0.068
organonitrogen compound catabolic process GO:1901565 179 0.067
regulation of cell cycle GO:0051726 73 0.067
signal transduction by phosphorylation GO:0023014 144 0.067
organophosphate catabolic process GO:0046434 148 0.066
angiogenesis GO:0001525 53 0.066
Human
positive regulation of molecular function GO:0044093 230 0.066
response to growth factor GO:0070848 189 0.066
Human
negative regulation of nucleic acid templated transcription GO:1903507 117 0.065
cellular response to growth factor stimulus GO:0071363 162 0.064
Human
vasculature development GO:0001944 70 0.064
Human
purine ribonucleoside catabolic process GO:0046130 124 0.064
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.064
regulation of angiogenesis GO:0045765 39 0.064
Human
cellular response to cycloheximide GO:0071409 4 0.064
response to mechanical stimulus GO:0009612 134 0.063
cellular component biogenesis GO:0044085 368 0.062
response to bacterium GO:0009617 200 0.061
response to other organism GO:0051707 220 0.061
gland development GO:0048732 155 0.061
glycosyl compound metabolic process GO:1901657 182 0.061
cellular response to steroid hormone stimulus GO:0071383 93 0.060
nucleoside metabolic process GO:0009116 179 0.060
positive regulation of rna biosynthetic process GO:1902680 197 0.060
nucleotide metabolic process GO:0009117 279 0.059
regeneration GO:0031099 163 0.059
regulation of nervous system development GO:0051960 264 0.059
developmental growth GO:0048589 100 0.057
regulation of mapk cascade GO:0043408 116 0.056
response to temperature stimulus GO:0009266 94 0.056
catabolic process GO:0009056 351 0.056
reproduction GO:0000003 245 0.055
neuron projection development GO:0031175 273 0.055
cell type specific apoptotic process GO:0097285 134 0.054
regulation of protein kinase activity GO:0045859 105 0.054
protein phosphorylation GO:0006468 345 0.053
endocytosis GO:0006897 84 0.053
positive regulation of cell differentiation GO:0045597 217 0.053
organic cyclic compound catabolic process GO:1901361 175 0.053
regulation of cytokine production GO:0001817 56 0.053
Human
cellular nitrogen compound catabolic process GO:0044270 163 0.053
purine ribonucleotide metabolic process GO:0009150 227 0.052
neuron development GO:0048666 286 0.052
purine nucleoside catabolic process GO:0006152 124 0.052
response to corticosterone GO:0051412 40 0.052
response to fluid shear stress GO:0034405 16 0.051
Human
positive regulation of immune system process GO:0002684 90 0.051
cell cycle GO:0007049 101 0.051
aging GO:0007568 241 0.049
cytokine production GO:0001816 61 0.048
Human
immune system development GO:0002520 41 0.048
Human
nucleoside phosphate metabolic process GO:0006753 283 0.048
growth GO:0040007 165 0.048
rhythmic process GO:0048511 156 0.047
response to decreased oxygen levels GO:0036293 237 0.047
negative regulation of molecular function GO:0044092 133 0.047
Human
cellular response to oxidative stress GO:0034599 76 0.047
response to light stimulus GO:0009416 52 0.046
single organism catabolic process GO:0044712 283 0.046
response to interleukin 1 GO:0070555 55 0.046
gtp catabolic process GO:0006184 71 0.046
response to estradiol GO:0032355 164 0.046
blood circulation GO:0008015 183 0.045
purine containing compound catabolic process GO:0072523 138 0.045
negative regulation of intracellular signal transduction GO:1902532 38 0.045
response to peptide hormone GO:0043434 278 0.045
purine containing compound metabolic process GO:0072521 253 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.044
carbon catabolite activation of transcription GO:0045991 1 0.043
nucleoside triphosphate catabolic process GO:0009143 123 0.043
regulation of kinase activity GO:0043549 117 0.043
ribonucleotide metabolic process GO:0009259 231 0.042
response to transforming growth factor beta GO:0071559 46 0.042
heterocycle catabolic process GO:0046700 167 0.042
positive regulation of phosphate metabolic process GO:0045937 262 0.042
single organism carbohydrate metabolic process GO:0044723 118 0.042
carbohydrate derivative catabolic process GO:1901136 147 0.042
synapse assembly GO:0007416 29 0.042
myelination GO:0042552 39 0.041
muscle tissue development GO:0060537 58 0.041
positive regulation of developmental process GO:0051094 283 0.041
response to estrogen GO:0043627 232 0.041
response to ethanol GO:0045471 162 0.041
cellular response to mycophenolic acid GO:0071506 2 0.041
response to mineralocorticoid GO:0051385 49 0.040
ribonucleoside triphosphate metabolic process GO:0009199 141 0.039
ribonucleoside triphosphate catabolic process GO:0009203 122 0.038
ras protein signal transduction GO:0007265 29 0.038
positive regulation of cell proliferation GO:0008284 249 0.038
Rat
leukocyte differentiation GO:0002521 30 0.038
long term synaptic potentiation GO:0060291 21 0.037
multicellular organismal reproductive process GO:0048609 233 0.037
regulation of transferase activity GO:0051338 123 0.037
regulation of membrane potential GO:0042391 110 0.037
negative regulation of response to stimulus GO:0048585 155 0.037
glycosyl compound catabolic process GO:1901658 126 0.036
synapse organization GO:0050808 46 0.036
purine nucleoside triphosphate metabolic process GO:0009144 141 0.036
regulation of organelle organization GO:0033043 80 0.036
enzyme linked receptor protein signaling pathway GO:0007167 116 0.036
muscle organ development GO:0007517 50 0.036
protein dephosphorylation GO:0006470 38 0.036
regulation of protein phosphorylation GO:0001932 183 0.034
cell cell signaling GO:0007267 335 0.034
heart morphogenesis GO:0003007 3 0.034
response to nutrient levels GO:0031667 370 0.034
dna metabolic process GO:0006259 96 0.033
cellular response to corticosteroid stimulus GO:0071384 69 0.033
female pregnancy GO:0007565 122 0.033
single organism behavior GO:0044708 130 0.033
heart process GO:0003015 57 0.033
negative regulation of signal transduction GO:0009968 83 0.033
gamete generation GO:0007276 124 0.033
nucleoside triphosphate metabolic process GO:0009141 144 0.033
kidney development GO:0001822 67 0.033
response to acid chemical GO:0001101 222 0.033
ribose phosphate metabolic process GO:0019693 235 0.032
cellular homeostasis GO:0019725 252 0.032
liver development GO:0001889 90 0.032
muscle cell proliferation GO:0033002 84 0.032
positive regulation of hydrolase activity GO:0051345 86 0.031
sensory organ development GO:0007423 74 0.031
protein transport GO:0015031 132 0.031
regulation of protein modification process GO:0031399 194 0.031
response to extracellular stimulus GO:0009991 380 0.031
response to testosterone GO:0033574 55 0.031
ribonucleotide catabolic process GO:0009261 136 0.031
cellular ketone metabolic process GO:0042180 51 0.031
cellular component movement GO:0006928 248 0.030
Human
regulation of synaptic transmission GO:0050804 141 0.030
cellular component assembly GO:0022607 360 0.030
regulation of protein serine threonine kinase activity GO:0071900 64 0.030
nucleotide catabolic process GO:0009166 139 0.029
regulation of dna metabolic process GO:0051052 60 0.029
heart contraction GO:0060047 57 0.029
regulation of osteoclast differentiation GO:0045670 8 0.029
response to dexamethasone GO:0071548 49 0.029
positive regulation of catalytic activity GO:0043085 184 0.029
axon development GO:0061564 96 0.029
response to oxygen levels GO:0070482 265 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.029
anatomical structure formation involved in morphogenesis GO:0048646 83 0.028
Human
multi multicellular organism process GO:0044706 138 0.028
regulation of erk1 and erk2 cascade GO:0070372 41 0.028
homeostatic process GO:0042592 331 0.028
response to transition metal nanoparticle GO:1990267 122 0.028
cellular response to lipid GO:0071396 201 0.027
regulation of cell differentiation GO:0045595 320 0.027
cell morphogenesis GO:0000902 142 0.027
regulation of neuron death GO:1901214 115 0.027
head development GO:0060322 247 0.026
positive regulation of transport GO:0051050 245 0.026
regulation of cellular component movement GO:0051270 150 0.026
Human
response to external biotic stimulus GO:0043207 221 0.026
regulation of heart contraction GO:0008016 48 0.026
small gtpase mediated signal transduction GO:0007264 36 0.026
cellular divalent inorganic cation homeostasis GO:0072503 162 0.026
negative regulation of neuron death GO:1901215 69 0.026
cell motility GO:0048870 202 0.026
Human
interleukin 1 mediated signaling pathway GO:0070498 2 0.025
viral transcription GO:0019083 2 0.025
negative regulation of phosphate metabolic process GO:0045936 80 0.025
cellular chemical homeostasis GO:0055082 247 0.025
negative regulation of nervous system development GO:0051961 79 0.025
regulation of anatomical structure morphogenesis GO:0022603 141 0.025
Human
regulation of cell migration GO:0030334 128 0.025
Human
positive regulation of cell communication GO:0010647 271 0.024
regulation of ras gtpase activity GO:0032318 32 0.024
positive regulation of cellular component movement GO:0051272 102 0.024
cellular response to metal ion GO:0071248 55 0.024
eye development GO:0001654 50 0.024
regulation of neuron differentiation GO:0045664 208 0.024
dephosphorylation GO:0016311 98 0.024
vesicle mediated transport GO:0016192 181 0.024
purine nucleoside metabolic process GO:0042278 169 0.024
taxis GO:0042330 67 0.023
learning GO:0007612 33 0.023
purine nucleoside monophosphate catabolic process GO:0009128 55 0.023
single organism reproductive process GO:0044702 297 0.023
metal ion transport GO:0030001 289 0.023
organic acid metabolic process GO:0006082 292 0.023
secretion by cell GO:0032940 248 0.023
positive regulation of nervous system development GO:0051962 178 0.023
developmental process involved in reproduction GO:0003006 159 0.023
positive regulation of g0 to g1 transition GO:0070318 2 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
cellular response to external stimulus GO:0071496 118 0.023
regulation of reactive oxygen species metabolic process GO:2000377 26 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
positive regulation of response to stimulus GO:0048584 285 0.022
chemical homeostasis GO:0048878 292 0.022
response to tumor necrosis factor GO:0034612 56 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
sexual reproduction GO:0019953 148 0.022
glomerular mesangial cell proliferation GO:0072110 4 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
single organism organelle organization GO:1902589 180 0.022
negative regulation of cell communication GO:0010648 158 0.022
striated muscle tissue development GO:0014706 58 0.022
regulation of cellular catabolic process GO:0031329 101 0.022
multicellular organismal signaling GO:0035637 44 0.022
positive regulation of osteoclast differentiation GO:0045672 5 0.022
response to carbohydrate GO:0009743 183 0.021
regulation of nucleotide catabolic process GO:0030811 65 0.021
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 1 0.021
action potential GO:0001508 54 0.021
protein complex assembly GO:0006461 263 0.021
response to retinoic acid GO:0032526 63 0.021
positive regulation of cellular catabolic process GO:0031331 71 0.021
organ regeneration GO:0031100 101 0.021
regulation of gene expression epigenetic GO:0040029 10 0.021
cellular metal ion homeostasis GO:0006875 172 0.021
multi organism reproductive process GO:0044703 262 0.020
regulation of cellular localization GO:0060341 263 0.020
negative regulation of cell development GO:0010721 82 0.020
cellular response to tumor necrosis factor GO:0071356 46 0.020
regulation of response to external stimulus GO:0032101 106 0.020
amine metabolic process GO:0009308 38 0.020
cytoplasmic transport GO:0016482 115 0.020
cellular macromolecule catabolic process GO:0044265 29 0.020
erk1 and erk2 cascade GO:0070371 48 0.020
regulation of catabolic process GO:0009894 113 0.020
synaptic transmission GO:0007268 235 0.020
regulation of nucleotide metabolic process GO:0006140 117 0.020
negative regulation of catalytic activity GO:0043086 103 0.019
Human
neuronal action potential GO:0019228 35 0.019
vascular process in circulatory system GO:0003018 96 0.019
positive regulation of cell development GO:0010720 176 0.019
erythrocyte differentiation GO:0030218 1 0.019
mitotic cell cycle GO:0000278 49 0.019
cytosolic calcium ion homeostasis GO:0051480 140 0.019
locomotor rhythm GO:0045475 1 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
cell cycle process GO:0022402 57 0.019
guanosine containing compound catabolic process GO:1901069 71 0.019
cellular response to camp GO:0071320 26 0.019
epithelial cell differentiation GO:0030855 71 0.019
positive regulation of cell migration GO:0030335 96 0.018
regulation of nucleoside metabolic process GO:0009118 66 0.018
response to nutrient GO:0007584 248 0.018
cellular response to glucocorticoid stimulus GO:0071385 68 0.018
regulation of immune system process GO:0002682 123 0.018
regulation of synaptic plasticity GO:0048167 70 0.018
regulation of metal ion transport GO:0010959 118 0.018
axon regeneration GO:0031103 28 0.018
developmental growth involved in morphogenesis GO:0060560 33 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
cellular amine metabolic process GO:0044106 38 0.017
ribonucleoside monophosphate catabolic process GO:0009158 55 0.017
mesoderm development GO:0007498 2 0.017
protein heterooligomerization GO:0051291 89 0.017
atp catabolic process GO:0006200 54 0.017
regulation of cellular response to stress GO:0080135 49 0.017
response to hyperoxia GO:0055093 45 0.017
rho protein signal transduction GO:0007266 11 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
positive regulation of phosphorylation GO:0042327 177 0.016
protein complex biogenesis GO:0070271 263 0.016
positive regulation of epithelial cell proliferation GO:0050679 32 0.016
response to isoquinoline alkaloid GO:0014072 28 0.016
divalent metal ion transport GO:0070838 132 0.016
organ morphogenesis GO:0009887 75 0.016
establishment of protein localization GO:0045184 141 0.016
positive regulation of cell proliferation involved in kidney development GO:1901724 4 0.016
negative regulation of phosphorylation GO:0042326 57 0.016
oxoacid metabolic process GO:0043436 290 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
regulation of smooth muscle cell proliferation GO:0048660 75 0.016
regulation of rho gtpase activity GO:0032319 17 0.016
negative regulation of osteoblast differentiation GO:0045668 2 0.016
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 1 0.016
circulatory system process GO:0003013 183 0.016
positive regulation of signal transduction GO:0009967 175 0.016
cellular macromolecule localization GO:0070727 122 0.016
transmembrane transport GO:0055085 412 0.016
muscle structure development GO:0061061 87 0.016
sensory perception GO:0007600 101 0.016
neuromuscular process GO:0050905 2 0.016
cellular response to alkaloid GO:0071312 25 0.016
sleep GO:0030431 30 0.015
neuron projection regeneration GO:0031102 35 0.015
response to hexose GO:0009746 144 0.015
digestive system development GO:0055123 41 0.015
Human
cellular response to nutrient levels GO:0031669 60 0.015
organelle organization GO:0006996 266 0.015
cell migration GO:0016477 197 0.015
Human
gliogenesis GO:0042063 93 0.015
single organism intracellular transport GO:1902582 166 0.015
regulation of vasculature development GO:1901342 44 0.015
Human
spermatogenesis GO:0007283 99 0.015
regulation of system process GO:0044057 208 0.015
regulation of hydrolase activity GO:0051336 143 0.015
Human
cellular response to abiotic stimulus GO:0071214 85 0.015
positive regulation of transcription factor import into nucleus GO:0042993 4 0.015
forebrain development GO:0030900 98 0.015
intracellular transport GO:0046907 185 0.015
negative regulation of protein modification process GO:0031400 52 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
regulation of blood circulation GO:1903522 110 0.015
macromolecular complex assembly GO:0065003 273 0.015
positive regulation of bone mineralization GO:0030501 4 0.014
brain development GO:0007420 247 0.014
glomerular mesangium development GO:0072109 4 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
oligodendrocyte differentiation GO:0048709 32 0.014
activation of cysteine type endopeptidase activity GO:0097202 4 0.014
gtp metabolic process GO:0046039 72 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.014
positive regulation of ras gtpase activity GO:0032320 28 0.014
transmission of nerve impulse GO:0019226 42 0.014
response to cold GO:0009409 29 0.014
positive regulation of cell motility GO:2000147 97 0.014
negative regulation of developmental process GO:0051093 125 0.014
Human
tumor necrosis factor production GO:0032640 13 0.014
gluconeogenesis GO:0006094 15 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
axonogenesis GO:0007409 71 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
regulation of glomerular mesangial cell proliferation GO:0072124 4 0.013
tube development GO:0035295 89 0.013
Human
regulation of cellular component organization GO:0051128 368 0.013
cellular response to topologically incorrect protein GO:0035967 3 0.013
protein maturation GO:0051604 68 0.013
Human
nucleoside monophosphate catabolic process GO:0009125 56 0.013
locomotion GO:0040011 237 0.013
Human
response to gamma radiation GO:0010332 24 0.013
cell part morphogenesis GO:0032990 123 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013

Klf4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.038
disease of cellular proliferation DOID:14566 0 0.038
organ system cancer DOID:0050686 0 0.038
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019