Rattus norvegicus

18 known processes

Klf3

Kruppel-like factor 3 (basic)

(Aliases: Tef-2,Bklf)

Klf3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.101
positive regulation of apoptotic process GO:0043065 154 0.097
positive regulation of programmed cell death GO:0043068 157 0.094
immune system process GO:0002376 204 0.086
negative regulation of phosphorus metabolic process GO:0010563 80 0.081
Rat
positive regulation of cell death GO:0010942 184 0.080
regulation of molecular function GO:0065009 398 0.078
Rat
regulation of phosphorylation GO:0042325 248 0.074
Rat
organelle organization GO:0006996 266 0.068
regulation of intracellular signal transduction GO:1902531 218 0.065
Rat
response to inorganic substance GO:0010035 377 0.064
Rat
protein complex subunit organization GO:0071822 302 0.063
protein phosphorylation GO:0006468 345 0.061
regulation of phosphate metabolic process GO:0019220 349 0.060
Rat
cellular component biogenesis GO:0044085 368 0.060
regulation of phosphorus metabolic process GO:0051174 349 0.059
Rat
apoptotic process GO:0006915 381 0.058
positive regulation of biosynthetic process GO:0009891 319 0.058
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.057
Rat
regulation of protein modification process GO:0031399 194 0.057
regulation of signal transduction GO:0009966 318 0.056
Rat
cellular component movement GO:0006928 248 0.055
intracellular signal transduction GO:0035556 314 0.054
Rat
cellular response to oxygen containing compound GO:1901701 386 0.054
single organism reproductive process GO:0044702 297 0.053
regulation of cellular protein metabolic process GO:0032268 267 0.052
single organism organelle organization GO:1902589 180 0.050
single organism intracellular transport GO:1902582 166 0.050
regulation of protein metabolic process GO:0051246 289 0.049
positive regulation of molecular function GO:0044093 230 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.049
Rat
positive regulation of protein metabolic process GO:0051247 178 0.048
regulation of cellular localization GO:0060341 263 0.048
cellular component assembly GO:0022607 360 0.047
regulation of protein phosphorylation GO:0001932 183 0.046
regulation of programmed cell death GO:0043067 341 0.046
actin filament based process GO:0030029 86 0.046
positive regulation of phosphate metabolic process GO:0045937 262 0.043
positive regulation of cellular biosynthetic process GO:0031328 295 0.043
Rat
establishment of protein localization GO:0045184 141 0.042
programmed cell death GO:0012501 392 0.041
cellular response to stress GO:0033554 269 0.041
Rat
regulation of rna metabolic process GO:0051252 391 0.041
Rat
tube development GO:0035295 89 0.040
regulation of apoptotic process GO:0042981 335 0.040
protein localization GO:0008104 191 0.039
regulation of multicellular organismal development GO:2000026 376 0.039
vesicle mediated transport GO:0016192 181 0.039
response to cytokine GO:0034097 215 0.039
negative regulation of metabolic process GO:0009892 331 0.037
Rat
muscle system process GO:0003012 115 0.036
Rat
negative regulation of phosphate metabolic process GO:0045936 80 0.036
Rat
response to reactive oxygen species GO:0000302 120 0.035
Rat
anatomical structure morphogenesis GO:0009653 298 0.035
cytoskeleton organization GO:0007010 111 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.034
cellular response to reactive oxygen species GO:0034614 55 0.033
Rat
positive regulation of transport GO:0051050 245 0.033
regulation of protein localization GO:0032880 81 0.033
macromolecular complex subunit organization GO:0043933 339 0.033
regulation of secretion GO:0051046 224 0.033
amine metabolic process GO:0009308 38 0.032
transcription dna templated GO:0006351 377 0.032
Rat
ras protein signal transduction GO:0007265 29 0.032
macromolecule localization GO:0033036 252 0.031
carboxylic acid metabolic process GO:0019752 289 0.031
cellular response to organonitrogen compound GO:0071417 197 0.031
protein complex assembly GO:0006461 263 0.031
organophosphate metabolic process GO:0019637 370 0.031
Rat
regulation of protein kinase activity GO:0045859 105 0.030
anterior posterior pattern specification GO:0009952 1 0.030
regulation of transcription dna templated GO:0006355 374 0.030
Rat
rna metabolic process GO:0016070 406 0.030
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.030
Rat
cellular response to organic cyclic compound GO:0071407 202 0.030
Rat
small gtpase mediated signal transduction GO:0007264 36 0.029
actin filament based movement GO:0030048 16 0.029
cell cell signaling GO:0007267 335 0.028
blood vessel morphogenesis GO:0048514 58 0.028
nuclear transport GO:0051169 49 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
reproductive process GO:0022414 372 0.027
mapk cascade GO:0000165 140 0.027
Rat
regulation of nucleocytoplasmic transport GO:0046822 28 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
Rat
response to decreased oxygen levels GO:0036293 237 0.026
cell cycle GO:0007049 101 0.026
heart morphogenesis GO:0003007 3 0.026
organonitrogen compound catabolic process GO:1901565 179 0.026
response to acid chemical GO:0001101 222 0.026
Rat
angiogenesis GO:0001525 53 0.026
cellular amino acid metabolic process GO:0006520 107 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
vasculogenesis GO:0001570 3 0.025
protein complex biogenesis GO:0070271 263 0.025
response to hydrogen peroxide GO:0042542 89 0.025
Rat
positive regulation of phosphorylation GO:0042327 177 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
actin cytoskeleton organization GO:0030036 73 0.025
organic acid metabolic process GO:0006082 292 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
Rat
regulation of kinase activity GO:0043549 117 0.024
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
ribonucleoside triphosphate metabolic process GO:0009199 141 0.024
response to other organism GO:0051707 220 0.024
positive regulation of cell development GO:0010720 176 0.024
protein transport GO:0015031 132 0.024
regulation of transferase activity GO:0051338 123 0.024
Rat
protein heterooligomerization GO:0051291 89 0.023
negative regulation of cell proliferation GO:0008285 119 0.023
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.023
Rat
positive regulation of gene expression GO:0010628 244 0.023
Rat
positive regulation of catalytic activity GO:0043085 184 0.023
negative regulation of signaling GO:0023057 157 0.023
Rat
lipid metabolic process GO:0006629 283 0.023
Rat
oxoacid metabolic process GO:0043436 290 0.023
immune system development GO:0002520 41 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
regulation of blood vessel endothelial cell migration GO:0043535 4 0.022
neuron death GO:0070997 127 0.022
negative regulation of response to stimulus GO:0048585 155 0.022
Rat
multicellular organismal reproductive process GO:0048609 233 0.022
response to metal ion GO:0010038 253 0.022
response to growth factor GO:0070848 189 0.022
cellular response to cytokine stimulus GO:0071345 127 0.022
response to oxidative stress GO:0006979 186 0.022
Rat
reproduction GO:0000003 245 0.022
negative regulation of developmental process GO:0051093 125 0.022
intracellular transport GO:0046907 185 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
cell adhesion GO:0007155 110 0.022
central nervous system development GO:0007417 311 0.022
cellular response to hormone stimulus GO:0032870 247 0.021
homeostatic process GO:0042592 331 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.021
Rat
positive regulation of rna metabolic process GO:0051254 203 0.021
Rat
cellular response to growth factor stimulus GO:0071363 162 0.021
axis specification GO:0009798 4 0.021
nucleic acid templated transcription GO:0097659 379 0.021
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
Rat
secretion GO:0046903 307 0.021
positive regulation of cell communication GO:0010647 271 0.021
cellular amine metabolic process GO:0044106 38 0.021
multicellular organism reproduction GO:0032504 233 0.020
negative regulation of molecular function GO:0044092 133 0.020
ribonucleoside catabolic process GO:0042454 126 0.020
secretion by cell GO:0032940 248 0.020
regulation of secretion by cell GO:1903530 208 0.020
negative regulation of apoptotic process GO:0043066 181 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
Rat
cell morphogenesis GO:0000902 142 0.020
ovulation cycle GO:0042698 67 0.020
positive regulation of intracellular signal transduction GO:1902533 138 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
organic substance catabolic process GO:1901575 316 0.020
positive regulation of intracellular protein transport GO:0090316 20 0.020
nucleotide metabolic process GO:0009117 279 0.019
cardiovascular system development GO:0072358 134 0.019
circulatory system development GO:0072359 134 0.019
cellular response to fluid shear stress GO:0071498 4 0.019
regulation of cell development GO:0060284 263 0.019
neuron differentiation GO:0030182 368 0.019
rna biosynthetic process GO:0032774 380 0.019
Rat
eye morphogenesis GO:0048592 4 0.019
negative regulation of signal transduction GO:0009968 83 0.019
Rat
cellular response to nitrogen compound GO:1901699 210 0.019
positive regulation of bone mineralization GO:0030501 4 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
synaptic transmission GO:0007268 235 0.019
positive regulation of protein modification process GO:0031401 142 0.019
multi organism reproductive process GO:0044703 262 0.018
bmp signaling pathway GO:0030509 4 0.018
regulation of cell differentiation GO:0045595 320 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
Rat
regulation of immune system process GO:0002682 123 0.018
cellular ketone metabolic process GO:0042180 51 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
negative regulation of transport GO:0051051 136 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
cellular macromolecule localization GO:0070727 122 0.018
cellular homeostasis GO:0019725 252 0.018
regulation of embryonic development GO:0045995 2 0.018
protein oligomerization GO:0051259 191 0.018
single organism biosynthetic process GO:0044711 342 0.018
regulation of neurogenesis GO:0050767 247 0.018
neuron development GO:0048666 286 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
macromolecular complex assembly GO:0065003 273 0.017
response to wounding GO:0009611 254 0.017
Rat
endocytosis GO:0006897 84 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
defense response GO:0006952 194 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.017
cellular protein localization GO:0034613 122 0.017
nucleoside catabolic process GO:0009164 126 0.017
cytoplasmic transport GO:0016482 115 0.017
motor neuron axon guidance GO:0008045 1 0.017
nucleocytoplasmic transport GO:0006913 48 0.017
aromatic compound catabolic process GO:0019439 168 0.017
cell migration GO:0016477 197 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
Rat
response to peptide GO:1901652 292 0.017
regulation of cell cycle GO:0051726 73 0.017
digestive tract development GO:0048565 39 0.016
cellular response to lipid GO:0071396 201 0.016
Rat
heterocycle catabolic process GO:0046700 167 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
organ regeneration GO:0031100 101 0.016
positive regulation of nucleocytoplasmic transport GO:0046824 17 0.016
response to estrogen GO:0043627 232 0.016
response to bacterium GO:0009617 200 0.016
cellular response to steroid hormone stimulus GO:0071383 93 0.016
muscle cell proliferation GO:0033002 84 0.016
Rat
heterotypic cell cell adhesion GO:0034113 2 0.016
cellular component morphogenesis GO:0032989 155 0.016
transmembrane transport GO:0055085 412 0.016
cellular chemical homeostasis GO:0055082 247 0.016
rhythmic process GO:0048511 156 0.016
aging GO:0007568 241 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
Rat
positive regulation of signaling GO:0023056 270 0.016
regulation of response to stress GO:0080134 126 0.016
blood vessel development GO:0001568 69 0.016
purine containing compound metabolic process GO:0072521 253 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
regulation of catalytic activity GO:0050790 304 0.016
Rat
peptidyl amino acid modification GO:0018193 126 0.016
regulation of cell proliferation GO:0042127 359 0.015
Rat
locomotion GO:0040011 237 0.015
negative regulation of gene expression GO:0010629 199 0.015
Rat
jnk cascade GO:0007254 28 0.015
negative regulation of catalytic activity GO:0043086 103 0.015
response to extracellular stimulus GO:0009991 380 0.015
regulation of nervous system development GO:0051960 264 0.015
regulation of protein transport GO:0051223 68 0.015
biological adhesion GO:0022610 110 0.015
ion transmembrane transport GO:0034220 365 0.015
response to glucocorticoid GO:0051384 223 0.015
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
response to nutrient levels GO:0031667 370 0.015
localization of cell GO:0051674 202 0.015
sex differentiation GO:0007548 113 0.015
negative regulation of cell death GO:0060548 229 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
positive regulation of developmental process GO:0051094 283 0.015
developmental process involved in reproduction GO:0003006 159 0.015
neuron projection development GO:0031175 273 0.014
proteolysis GO:0006508 175 0.014
digestive system development GO:0055123 41 0.014
response to external biotic stimulus GO:0043207 221 0.014
reproductive system development GO:0061458 128 0.014
catabolic process GO:0009056 351 0.014
cellular response to tumor necrosis factor GO:0071356 46 0.014
female pregnancy GO:0007565 122 0.014
purine containing compound catabolic process GO:0072523 138 0.014
regulation of hormone levels GO:0010817 187 0.014
stress activated protein kinase signaling cascade GO:0031098 37 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
Rat
positive regulation of cellular component organization GO:0051130 200 0.014
response to ketone GO:1901654 182 0.014
single organism catabolic process GO:0044712 283 0.014
cellular response to corticosteroid stimulus GO:0071384 69 0.014
gamete generation GO:0007276 124 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
Rat
response to corticosteroid GO:0031960 235 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
cell fate determination GO:0001709 2 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
response to toxic substance GO:0009636 133 0.013
negative regulation of secretion GO:0051048 82 0.013
response to hypoxia GO:0001666 231 0.013
lipid biosynthetic process GO:0008610 128 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
cell projection organization GO:0030030 302 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
Rat
negative regulation of cell development GO:0010721 82 0.013
regulation of organ formation GO:0003156 2 0.013
response to oxygen levels GO:0070482 265 0.013
single organism cellular localization GO:1902580 102 0.013
axonogenesis GO:0007409 71 0.013
response to biotic stimulus GO:0009607 226 0.013
regulation of cell projection organization GO:0031344 175 0.013
heart development GO:0007507 72 0.013
small molecule biosynthetic process GO:0044283 124 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
organ morphogenesis GO:0009887 75 0.013
negative regulation of secretion by cell GO:1903531 72 0.013
response to tumor necrosis factor GO:0034612 56 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
response to retinoic acid GO:0032526 63 0.012
Rat
cation homeostasis GO:0055080 195 0.012
female sex differentiation GO:0046660 59 0.012
gastrulation GO:0007369 2 0.012
regulation of fat cell differentiation GO:0045598 3 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
response to nutrient GO:0007584 248 0.012
cell type specific apoptotic process GO:0097285 134 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
positive regulation of neuron death GO:1901216 43 0.012
regeneration GO:0031099 163 0.012
anion transport GO:0006820 178 0.012
cellular catabolic process GO:0044248 295 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
regulation of response to wounding GO:1903034 69 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
regulation of rna biosynthetic process GO:2001141 381 0.012
Rat
immune response GO:0006955 104 0.012
negative regulation of erk1 and erk2 cascade GO:0070373 9 0.012
Rat
neurological system process GO:0050877 219 0.012
positive regulation of protein transport GO:0051222 41 0.012
response to ethanol GO:0045471 162 0.012
intracellular protein transport GO:0006886 79 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
sexual reproduction GO:0019953 148 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
cellular response to peptide GO:1901653 133 0.011
regulation of muscle system process GO:0090257 79 0.011
Rat
axon development GO:0061564 96 0.011
cytokine biosynthetic process GO:0042089 3 0.011
cellular response to oxidative stress GO:0034599 76 0.011
Rat
positive regulation of nucleotide catabolic process GO:0030813 53 0.011
cytokine production GO:0001816 61 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
Rat
embryonic appendage morphogenesis GO:0035113 4 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
development of primary female sexual characteristics GO:0046545 56 0.011
regulation of cytokine biosynthetic process GO:0042035 3 0.011
activation of cysteine type endopeptidase activity GO:0097202 4 0.011
development of primary sexual characteristics GO:0045137 107 0.011
positive regulation of signal transduction GO:0009967 175 0.011
regulation of response to external stimulus GO:0032101 106 0.011
regulation of interleukin 8 production GO:0032677 2 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
rho protein signal transduction GO:0007266 11 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
head development GO:0060322 247 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
mechanoreceptor differentiation GO:0042490 2 0.011
response to glucose GO:0009749 136 0.011
circulatory system process GO:0003013 183 0.011
cell activation GO:0001775 97 0.011
regulation of cellular component organization GO:0051128 368 0.011
regulation of neuron projection development GO:0010975 161 0.011
spermatogenesis GO:0007283 99 0.011
organic acid transport GO:0015849 116 0.011
regulation of intracellular protein transport GO:0033157 34 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
dna metabolic process GO:0006259 96 0.011
nucleoside metabolic process GO:0009116 179 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
negative regulation of phosphorylation GO:0042326 57 0.011
Rat
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
non canonical wnt signaling pathway GO:0035567 3 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
cell motility GO:0048870 202 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
ribonucleotide metabolic process GO:0009259 231 0.010
negative regulation of cell migration involved in sprouting angiogenesis GO:0090051 1 0.010
hair cell differentiation GO:0035315 2 0.010
ossification GO:0001503 70 0.010
gtp catabolic process GO:0006184 71 0.010
inner ear receptor cell differentiation GO:0060113 2 0.010
positive regulation of hydrolase activity GO:0051345 86 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
peptide biosynthetic process GO:0043043 3 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
reproductive structure development GO:0048608 128 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
Rat
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
activation of immune response GO:0002253 26 0.010
male gamete generation GO:0048232 99 0.010
positive regulation of cytoplasmic transport GO:1903651 32 0.010
positive regulation of immune system process GO:0002684 90 0.010

Klf3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023