Rattus norvegicus

18 known processes

Klf1

Kruppel-like factor 1 (erythroid)

Klf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell proliferation GO:0042127 359 0.142
Rat
response to extracellular stimulus GO:0009991 380 0.114
intracellular signal transduction GO:0035556 314 0.107
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.098
Human Rat
response to estradiol GO:0032355 164 0.094
cellular response to oxygen containing compound GO:1901701 386 0.076
response to cytokine GO:0034097 215 0.072
positive regulation of cell proliferation GO:0008284 249 0.068
Rat
cardiovascular system development GO:0072358 134 0.067
programmed cell death GO:0012501 392 0.065
positive regulation of cellular biosynthetic process GO:0031328 295 0.065
Human Rat
neuron differentiation GO:0030182 368 0.063
cellular response to lipid GO:0071396 201 0.062
Rat
regulation of multicellular organismal development GO:2000026 376 0.061
regulation of rna metabolic process GO:0051252 391 0.056
Human Rat
response to other organism GO:0051707 220 0.056
response to nutrient levels GO:0031667 370 0.055
homeostatic process GO:0042592 331 0.055
Human
response to estrogen GO:0043627 232 0.054
cell projection organization GO:0030030 302 0.054
positive regulation of signaling GO:0023056 270 0.052
response to acid chemical GO:0001101 222 0.052
Rat
response to nutrient GO:0007584 248 0.051
rna metabolic process GO:0016070 406 0.051
Human Rat
cell migration GO:0016477 197 0.051
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.048
Human Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.048
Human Rat
regulation of behavior GO:0050795 61 0.048
organic acid transport GO:0015849 116 0.047
tissue development GO:0009888 252 0.047
circulatory system development GO:0072359 134 0.045
response to lipopolysaccharide GO:0032496 191 0.043
multi multicellular organism process GO:0044706 138 0.043
cellular amine metabolic process GO:0044106 38 0.043
positive regulation of cell communication GO:0010647 271 0.043
protein phosphorylation GO:0006468 345 0.042
macromolecular complex assembly GO:0065003 273 0.042
organic anion transport GO:0015711 132 0.042
regulation of programmed cell death GO:0043067 341 0.041
positive regulation of biosynthetic process GO:0009891 319 0.041
Human Rat
transmembrane transport GO:0055085 412 0.040
cellular response to endogenous stimulus GO:0071495 377 0.040
epithelium development GO:0060429 96 0.040
negative regulation of macromolecule metabolic process GO:0010605 260 0.040
Rat
secretion by cell GO:0032940 248 0.039
multi organism reproductive process GO:0044703 262 0.039
regulation of cell projection size GO:0032536 1 0.039
regulation of protein metabolic process GO:0051246 289 0.039
brain development GO:0007420 247 0.039
regulation of cellular component organization GO:0051128 368 0.038
head development GO:0060322 247 0.038
neuron development GO:0048666 286 0.038
apoptotic process GO:0006915 381 0.038
reproductive process GO:0022414 372 0.037
positive regulation of rna metabolic process GO:0051254 203 0.037
Human Rat
positive regulation of cell migration GO:0030335 96 0.037
immune system process GO:0002376 204 0.036
Human
negative regulation of multicellular organismal process GO:0051241 203 0.036
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.036
Human Rat
positive regulation of gene expression GO:0010628 244 0.035
Human Rat
negative regulation of cellular metabolic process GO:0031324 281 0.035
Rat
reproductive system development GO:0061458 128 0.035
locomotion GO:0040011 237 0.034
protein complex biogenesis GO:0070271 263 0.034
rna biosynthetic process GO:0032774 380 0.033
Human Rat
regulation of cellular protein metabolic process GO:0032268 267 0.033
organic acid metabolic process GO:0006082 292 0.033
defense response GO:0006952 194 0.033
cellular component movement GO:0006928 248 0.033
regulation of blood vessel size GO:0050880 89 0.033
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.033
regulation of molecular function GO:0065009 398 0.032
Rat
cation homeostasis GO:0055080 195 0.032
response to oxygen levels GO:0070482 265 0.032
positive regulation of rna biosynthetic process GO:1902680 197 0.032
Human Rat
regulation of intracellular signal transduction GO:1902531 218 0.031
Rat
amine metabolic process GO:0009308 38 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.031
Rat
cation transport GO:0006812 382 0.031
taxis GO:0042330 67 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.030
positive regulation of molecular function GO:0044093 230 0.030
regulation of anatomical structure size GO:0090066 135 0.030
cellular ketone metabolic process GO:0042180 51 0.029
anion transport GO:0006820 178 0.029
transcription dna templated GO:0006351 377 0.029
Human Rat
muscle contraction GO:0006936 88 0.029
single organism reproductive process GO:0044702 297 0.028
positive regulation of apoptotic process GO:0043065 154 0.028
response to radiation GO:0009314 137 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
Human Rat
negative regulation of developmental process GO:0051093 125 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
localization of cell GO:0051674 202 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
neuron projection development GO:0031175 273 0.027
positive regulation of programmed cell death GO:0043068 157 0.027
response to inorganic substance GO:0010035 377 0.027
Rat
regeneration GO:0031099 163 0.027
positive regulation of protein modification process GO:0031401 142 0.026
protein oligomerization GO:0051259 191 0.026
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.026
response to carbohydrate GO:0009743 183 0.026
tube development GO:0035295 89 0.026
secretion GO:0046903 307 0.026
response to hypoxia GO:0001666 231 0.026
calcium ion homeostasis GO:0055074 162 0.026
cellular divalent inorganic cation homeostasis GO:0072503 162 0.026
nucleic acid templated transcription GO:0097659 379 0.026
Human Rat
positive regulation of cell motility GO:2000147 97 0.026
cellular calcium ion homeostasis GO:0006874 160 0.025
reproductive structure development GO:0048608 128 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.024
Rat
regulation of cell differentiation GO:0045595 320 0.024
central nervous system development GO:0007417 311 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
Rat
negative regulation of rna biosynthetic process GO:1902679 118 0.024
Rat
chemical homeostasis GO:0048878 292 0.023
cellular response to abiotic stimulus GO:0071214 85 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
regulation of phosphorus metabolic process GO:0051174 349 0.023
Rat
positive regulation of response to stimulus GO:0048584 285 0.023
response to peptide hormone GO:0043434 278 0.022
regulation of apoptotic process GO:0042981 335 0.022
response to bacterium GO:0009617 200 0.022
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.022
response to oxidative stress GO:0006979 186 0.022
Rat
regulation of blood pressure GO:0008217 83 0.022
male sex differentiation GO:0046661 64 0.022
positive regulation of developmental process GO:0051094 283 0.022
growth GO:0040007 165 0.022
metal ion homeostasis GO:0055065 186 0.022
regulation of catalytic activity GO:0050790 304 0.022
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
response to decreased oxygen levels GO:0036293 237 0.021
female pregnancy GO:0007565 122 0.021
regulation of tube size GO:0035150 89 0.021
negative regulation of metabolic process GO:0009892 331 0.021
Rat
cellular component assembly GO:0022607 360 0.021
response to corticosteroid GO:0031960 235 0.021
positive regulation of cellular component movement GO:0051272 102 0.021
cellular component biogenesis GO:0044085 368 0.021
positive regulation of protein phosphorylation GO:0001934 135 0.021
negative regulation of signaling GO:0023057 157 0.021
Rat
regulation of transcription dna templated GO:0006355 374 0.021
Human Rat
regulation of cell projection organization GO:0031344 175 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
heart morphogenesis GO:0003007 3 0.020
regulation of ion transport GO:0043269 245 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
response to transition metal nanoparticle GO:1990267 122 0.020
positive regulation of locomotion GO:0040017 102 0.020
metal ion transport GO:0030001 289 0.020
response to ethanol GO:0045471 162 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
regulation of cellular component biogenesis GO:0044087 86 0.020
peptidyl amino acid modification GO:0018193 126 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
development of primary sexual characteristics GO:0045137 107 0.020
gonad development GO:0008406 104 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
regulation of membrane potential GO:0042391 110 0.019
positive regulation of transport GO:0051050 245 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
single organism biosynthetic process GO:0044711 342 0.019
regulation of protein modification process GO:0031399 194 0.019
reproduction GO:0000003 245 0.019
single organism organelle organization GO:1902589 180 0.019
gamete generation GO:0007276 124 0.018
cellular homeostasis GO:0019725 252 0.018
neuron projection morphogenesis GO:0048812 122 0.018
developmental process involved in reproduction GO:0003006 159 0.018
cell activation GO:0001775 97 0.018
respiratory system development GO:0060541 45 0.018
cellular response to external stimulus GO:0071496 118 0.018
chemotaxis GO:0006935 66 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
response to retinoic acid GO:0032526 63 0.018
Rat
negative regulation of gene expression GO:0010629 199 0.018
Rat
vascular process in circulatory system GO:0003018 96 0.018
steroid metabolic process GO:0008202 73 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
response to ionizing radiation GO:0010212 59 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
Rat
circulatory system process GO:0003013 183 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
Rat
protein complex assembly GO:0006461 263 0.017
response to vitamin GO:0033273 131 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
Rat
regulation of locomotion GO:0040012 148 0.017
regulation of phosphorylation GO:0042325 248 0.017
Rat
cellular response to stress GO:0033554 269 0.017
Rat
regulation of signal transduction GO:0009966 318 0.017
Rat
multicellular organism reproduction GO:0032504 233 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
Human Rat
cytosolic calcium ion homeostasis GO:0051480 140 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
muscle system process GO:0003012 115 0.017
Rat
regulation of cell migration GO:0030334 128 0.017
ion homeostasis GO:0050801 212 0.016
lipid metabolic process GO:0006629 283 0.016
Rat
cellular chemical homeostasis GO:0055082 247 0.016
protein complex subunit organization GO:0071822 302 0.016
blood circulation GO:0008015 183 0.016
tissue morphogenesis GO:0048729 22 0.016
cell adhesion GO:0007155 110 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
anterior posterior pattern specification GO:0009952 1 0.016
calcium ion transport GO:0006816 131 0.016
urogenital system development GO:0001655 78 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
Rat
inorganic cation transmembrane transport GO:0098662 202 0.015
sex differentiation GO:0007548 113 0.015
cellular response to acid chemical GO:0071229 75 0.015
Rat
oxoacid metabolic process GO:0043436 290 0.015
regulation of immune system process GO:0002682 123 0.015
positive regulation of cell death GO:0010942 184 0.015
muscle tissue development GO:0060537 58 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
actin filament organization GO:0007015 42 0.015
gland development GO:0048732 155 0.015
regulation of cell motility GO:2000145 131 0.015
biological adhesion GO:0022610 110 0.015
ion transmembrane transport GO:0034220 365 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
Rat
regulation of neuron death GO:1901214 115 0.015
vasoconstriction GO:0042310 54 0.015
ossification GO:0001503 70 0.015
positive regulation of signal transduction GO:0009967 175 0.015
forebrain development GO:0030900 98 0.015
positive regulation of transferase activity GO:0051347 81 0.014
response to wounding GO:0009611 254 0.014
Rat
regulation of body fluid levels GO:0050878 90 0.014
positive regulation of nervous system development GO:0051962 178 0.014
chromosome segregation GO:0007059 2 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
Rat
lipid biosynthetic process GO:0008610 128 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
sexual reproduction GO:0019953 148 0.014
response to external biotic stimulus GO:0043207 221 0.014
regulation of nervous system development GO:0051960 264 0.014
leukocyte migration GO:0050900 38 0.014
non canonical wnt signaling pathway GO:0035567 3 0.014
response to biotic stimulus GO:0009607 226 0.014
positive regulation of immune system process GO:0002684 90 0.014
lung development GO:0030324 43 0.014
blood vessel development GO:0001568 69 0.014
heterocycle catabolic process GO:0046700 167 0.014
inflammatory response GO:0006954 150 0.014
cell projection morphogenesis GO:0048858 123 0.014
catabolic process GO:0009056 351 0.013
regulation of response to stress GO:0080134 126 0.013
regulation of neurogenesis GO:0050767 247 0.013
activation of protein kinase activity GO:0032147 47 0.013
regulation of system process GO:0044057 208 0.013
Rat
male gonad development GO:0008584 59 0.013
cation transmembrane transport GO:0098655 263 0.013
response to monosaccharide GO:0034284 159 0.013
response to peptide GO:1901652 292 0.013
organelle organization GO:0006996 266 0.013
response to metal ion GO:0010038 253 0.013
vasculature development GO:0001944 70 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
Rat
aging GO:0007568 241 0.013
negative regulation of cell death GO:0060548 229 0.013
regulation of growth GO:0040008 105 0.013
cell morphogenesis GO:0000902 142 0.012
regulation of hormone levels GO:0010817 187 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
acute inflammatory response GO:0002526 58 0.012
organ morphogenesis GO:0009887 75 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
cell motility GO:0048870 202 0.012
response to hexose GO:0009746 144 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
multicellular organism growth GO:0035264 1 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
Rat
nucleotide biosynthetic process GO:0009165 98 0.012
nitrogen compound transport GO:0071705 229 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
acid secretion GO:0046717 48 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
carboxylic acid transport GO:0046942 115 0.012
ovulation cycle GO:0042698 67 0.012
fatty acid biosynthetic process GO:0006633 33 0.012
cellular catabolic process GO:0044248 295 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
synaptic transmission GO:0007268 235 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
Rat
purine containing compound catabolic process GO:0072523 138 0.012
circadian rhythm GO:0007623 88 0.012
axis specification GO:0009798 4 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
cytoskeleton organization GO:0007010 111 0.012
response to activity GO:0014823 73 0.012
hair cycle GO:0042633 3 0.012
regulation of cell adhesion GO:0030155 52 0.011
positive regulation of behavior GO:0048520 38 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
cell growth GO:0016049 104 0.011
proteolysis GO:0006508 175 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
Human Rat
carbohydrate derivative metabolic process GO:1901135 346 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
cellular cation homeostasis GO:0030003 180 0.011
regulation of metal ion transport GO:0010959 118 0.011
signal release GO:0023061 145 0.011
dna metabolic process GO:0006259 96 0.011
ras protein signal transduction GO:0007265 29 0.011
immune response GO:0006955 104 0.011
regulation of cell development GO:0060284 263 0.011
negative regulation of cell development GO:0010721 82 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
Rat
metestrus GO:0060210 1 0.011
regulation of kinase activity GO:0043549 117 0.011
Rat
single organism catabolic process GO:0044712 283 0.011
response to ketone GO:1901654 182 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
eye morphogenesis GO:0048592 4 0.011
muscle structure development GO:0061061 87 0.011
nucleotide metabolic process GO:0009117 279 0.011
behavior GO:0007610 205 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
regulation of blood circulation GO:1903522 110 0.011
brain renin angiotensin system GO:0002035 3 0.011
unsaturated fatty acid metabolic process GO:0033559 39 0.010
monocarboxylic acid transport GO:0015718 52 0.010
rhythmic process GO:0048511 156 0.010
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.010
gastrulation GO:0007369 2 0.010
blood vessel morphogenesis GO:0048514 58 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
regulation of epithelial cell proliferation GO:0050678 49 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
development of primary male sexual characteristics GO:0046546 59 0.010
response to glucose GO:0009749 136 0.010
protein localization GO:0008104 191 0.010
positive regulation of ion transport GO:0043270 94 0.010
negative regulation of transport GO:0051051 136 0.010
positive regulation of lipid metabolic process GO:0045834 33 0.010

Klf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
Human
nervous system disease DOID:863 0 0.039