Rattus norvegicus

0 known processes

Klhl31

kelch-like 31 (Drosophila)

(Aliases: RGD1560540)

Klhl31 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of molecular function GO:0065009 398 0.124
rna metabolic process GO:0016070 406 0.114
negative regulation of cellular metabolic process GO:0031324 281 0.113
cellular component assembly GO:0022607 360 0.113
regulation of cell proliferation GO:0042127 359 0.098
single organism reproductive process GO:0044702 297 0.094
regulation of cell differentiation GO:0045595 320 0.086
regulation of nucleic acid templated transcription GO:1903506 380 0.085
regulation of rna biosynthetic process GO:2001141 381 0.083
regulation of neurogenesis GO:0050767 247 0.081
transcription dna templated GO:0006351 377 0.080
ion transmembrane transport GO:0034220 365 0.080
positive regulation of biosynthetic process GO:0009891 319 0.079
transcription from rna polymerase ii promoter GO:0006366 252 0.076
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.071
regulation of rna metabolic process GO:0051252 391 0.070
regulation of multicellular organismal development GO:2000026 376 0.069
regulation of cellular component organization GO:0051128 368 0.067
neuron differentiation GO:0030182 368 0.066
rna biosynthetic process GO:0032774 380 0.065
regulation of transcription dna templated GO:0006355 374 0.065
cellular response to organic cyclic compound GO:0071407 202 0.063
negative regulation of metabolic process GO:0009892 331 0.062
neuron development GO:0048666 286 0.061
regulation of ion transmembrane transporter activity GO:0032412 48 0.060
anatomical structure morphogenesis GO:0009653 298 0.059
homeostatic process GO:0042592 331 0.059
regulation of cell development GO:0060284 263 0.059
positive regulation of phosphate metabolic process GO:0045937 262 0.058
positive regulation of cellular biosynthetic process GO:0031328 295 0.058
positive regulation of cell development GO:0010720 176 0.058
central nervous system development GO:0007417 311 0.058
calcium ion homeostasis GO:0055074 162 0.058
positive regulation of cell proliferation GO:0008284 249 0.056
regulation of system process GO:0044057 208 0.055
positive regulation of rna biosynthetic process GO:1902680 197 0.055
reproduction GO:0000003 245 0.054
reproductive process GO:0022414 372 0.053
cation transport GO:0006812 382 0.053
regulation of cellular localization GO:0060341 263 0.052
negative regulation of cellular biosynthetic process GO:0031327 161 0.052
cell projection organization GO:0030030 302 0.052
multicellular organismal reproductive process GO:0048609 233 0.050
cell morphogenesis GO:0000902 142 0.050
cell projection morphogenesis GO:0048858 123 0.050
positive regulation of cell differentiation GO:0045597 217 0.050
cellular component biogenesis GO:0044085 368 0.049
wound healing GO:0042060 122 0.049
cell part morphogenesis GO:0032990 123 0.048
nucleic acid templated transcription GO:0097659 379 0.048
tissue development GO:0009888 252 0.048
cell cell signaling GO:0007267 335 0.048
macromolecular complex subunit organization GO:0043933 339 0.047
cellular response to hormone stimulus GO:0032870 247 0.047
programmed cell death GO:0012501 392 0.046
negative regulation of macromolecule metabolic process GO:0010605 260 0.046
regulation of signal transduction GO:0009966 318 0.045
positive regulation of nervous system development GO:0051962 178 0.045
positive regulation of rna metabolic process GO:0051254 203 0.045
positive regulation of multicellular organismal process GO:0051240 387 0.045
neuron projection development GO:0031175 273 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
cellular component morphogenesis GO:0032989 155 0.043
multicellular organism reproduction GO:0032504 233 0.043
positive regulation of neurogenesis GO:0050769 165 0.043
regulation of cellular ketone metabolic process GO:0010565 27 0.043
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.042
intracellular signal transduction GO:0035556 314 0.042
macromolecular complex assembly GO:0065003 273 0.041
regulation of membrane potential GO:0042391 110 0.041
developmental process involved in reproduction GO:0003006 159 0.041
neuron projection morphogenesis GO:0048812 122 0.041
negative regulation of gene expression GO:0010629 199 0.040
positive regulation of programmed cell death GO:0043068 157 0.040
regulation of nervous system development GO:0051960 264 0.040
anterior posterior pattern specification GO:0009952 1 0.039
negative regulation of biosynthetic process GO:0009890 168 0.039
cellular calcium ion homeostasis GO:0006874 160 0.037
response to hypoxia GO:0001666 231 0.037
organelle organization GO:0006996 266 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.036
locomotion GO:0040011 237 0.036
cellular chemical homeostasis GO:0055082 247 0.036
neurological system process GO:0050877 219 0.036
protein phosphorylation GO:0006468 345 0.035
positive regulation of cell communication GO:0010647 271 0.035
cellular cation homeostasis GO:0030003 180 0.035
sexual reproduction GO:0019953 148 0.035
protein complex subunit organization GO:0071822 302 0.035
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.034
metal ion transport GO:0030001 289 0.034
positive regulation of molecular function GO:0044093 230 0.033
positive regulation of response to stimulus GO:0048584 285 0.033
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.033
positive regulation of cell death GO:0010942 184 0.033
transmembrane transport GO:0055085 412 0.032
response to estradiol GO:0032355 164 0.032
bmp signaling pathway GO:0030509 4 0.032
gamete generation GO:0007276 124 0.032
localization of cell GO:0051674 202 0.032
positive regulation of developmental process GO:0051094 283 0.031
apoptotic process GO:0006915 381 0.031
synaptic transmission GO:0007268 235 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.031
response to carbohydrate GO:0009743 183 0.031
ribonucleotide metabolic process GO:0009259 231 0.031
cytosolic calcium ion homeostasis GO:0051480 140 0.030
negative regulation of rna biosynthetic process GO:1902679 118 0.030
axonogenesis GO:0007409 71 0.030
cell growth GO:0016049 104 0.030
regulation of transporter activity GO:0032409 50 0.030
cellular ketone metabolic process GO:0042180 51 0.030
cellular ion homeostasis GO:0006873 184 0.030
negative regulation of rna metabolic process GO:0051253 123 0.030
response to estrogen GO:0043627 232 0.029
positive regulation of gene expression GO:0010628 244 0.029
brain development GO:0007420 247 0.029
single organism organelle organization GO:1902589 180 0.029
negative regulation of developmental process GO:0051093 125 0.029
multi organism reproductive process GO:0044703 262 0.029
regulation of intracellular signal transduction GO:1902531 218 0.029
cellular metal ion homeostasis GO:0006875 172 0.028
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.028
protein complex assembly GO:0006461 263 0.028
positive regulation of nucleic acid templated transcription GO:1903508 197 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
protein complex biogenesis GO:0070271 263 0.028
growth GO:0040007 165 0.028
metal ion homeostasis GO:0055065 186 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
muscle system process GO:0003012 115 0.028
regulation of protein metabolic process GO:0051246 289 0.027
regulation of growth GO:0040008 105 0.027
chemical homeostasis GO:0048878 292 0.027
divalent inorganic cation homeostasis GO:0072507 165 0.027
response to wounding GO:0009611 254 0.027
regulation of transmembrane transport GO:0034762 122 0.027
cellular response to stress GO:0033554 269 0.027
response to mechanical stimulus GO:0009612 134 0.026
response to decreased oxygen levels GO:0036293 237 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
regulation of transmembrane transporter activity GO:0022898 49 0.026
cellular divalent inorganic cation homeostasis GO:0072503 162 0.026
purine containing compound metabolic process GO:0072521 253 0.026
positive regulation of neuron differentiation GO:0045666 126 0.025
regulation of neuron differentiation GO:0045664 208 0.025
cellular catabolic process GO:0044248 295 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
response to glucocorticoid GO:0051384 223 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.025
circulatory system process GO:0003013 183 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
nucleotide metabolic process GO:0009117 279 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.024
epithelium development GO:0060429 96 0.024
organic substance catabolic process GO:1901575 316 0.024
cellular response to alcohol GO:0097306 87 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
heart morphogenesis GO:0003007 3 0.024
cellular nitrogen compound catabolic process GO:0044270 163 0.024
inorganic cation transmembrane transport GO:0098662 202 0.024
regulation of muscle system process GO:0090257 79 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.023
catabolic process GO:0009056 351 0.023
divalent inorganic cation transport GO:0072511 134 0.023
negative regulation of transcription dna templated GO:0045892 116 0.023
eye morphogenesis GO:0048592 4 0.023
cellular homeostasis GO:0019725 252 0.023
cellular amine metabolic process GO:0044106 38 0.023
positive regulation of cell projection organization GO:0031346 111 0.023
regulation of apoptotic process GO:0042981 335 0.022
head development GO:0060322 247 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
aging GO:0007568 241 0.022
regulation of organelle organization GO:0033043 80 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
regulation of programmed cell death GO:0043067 341 0.022
response to oxygen levels GO:0070482 265 0.022
positive regulation of signal transduction GO:0009967 175 0.022
negative regulation of transport GO:0051051 136 0.022
action potential GO:0001508 54 0.022
regulation of cell growth GO:0001558 85 0.022
response to growth factor GO:0070848 189 0.022
regulation of neuron projection development GO:0010975 161 0.022
cellular component movement GO:0006928 248 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
negative regulation of cell differentiation GO:0045596 99 0.021
cation transmembrane transport GO:0098655 263 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
ribose phosphate metabolic process GO:0019693 235 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
ras protein signal transduction GO:0007265 29 0.020
regulation of catalytic activity GO:0050790 304 0.020
cellular response to lipid GO:0071396 201 0.020
organ morphogenesis GO:0009887 75 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
regulation of cell motility GO:2000145 131 0.019
regulation of phosphorylation GO:0042325 248 0.019
ribonucleoside triphosphate metabolic process GO:0009199 141 0.019
anatomical structure formation involved in morphogenesis GO:0048646 83 0.019
regulation of metal ion transport GO:0010959 118 0.019
positive regulation of signaling GO:0023056 270 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
organophosphate metabolic process GO:0019637 370 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
single organism membrane organization GO:0044802 74 0.019
cytoskeleton organization GO:0007010 111 0.019
regulation of secretion by cell GO:1903530 208 0.019
heart contraction GO:0060047 57 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
peptidyl amino acid modification GO:0018193 126 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
regulation of transferase activity GO:0051338 123 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
protein localization GO:0008104 191 0.018
regulation of protein modification process GO:0031399 194 0.018
single organism catabolic process GO:0044712 283 0.018
protein oligomerization GO:0051259 191 0.018
dephosphorylation GO:0016311 98 0.018
negative regulation of cell communication GO:0010648 158 0.018
actin filament based process GO:0030029 86 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
cardiovascular system development GO:0072358 134 0.018
axon development GO:0061564 96 0.018
regulation of homeostatic process GO:0032844 101 0.018
macromolecule localization GO:0033036 252 0.018
negative regulation of secretion by cell GO:1903531 72 0.017
amine metabolic process GO:0009308 38 0.017
negative regulation of cell death GO:0060548 229 0.017
cardiac muscle cell contraction GO:0086003 10 0.017
negative regulation of molecular function GO:0044092 133 0.017
multi multicellular organism process GO:0044706 138 0.017
ossification GO:0001503 70 0.017
positive regulation of neuron projection development GO:0010976 99 0.017
cell type specific apoptotic process GO:0097285 134 0.017
regulation of mapk cascade GO:0043408 116 0.017
regulation of hydrolase activity GO:0051336 143 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
organic acid metabolic process GO:0006082 292 0.017
cation homeostasis GO:0055080 195 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
organ formation GO:0048645 3 0.016
cell migration GO:0016477 197 0.016
response to radiation GO:0009314 137 0.016
neuron death GO:0070997 127 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
blood circulation GO:0008015 183 0.016
axis specification GO:0009798 4 0.016
tube development GO:0035295 89 0.016
response to light stimulus GO:0009416 52 0.016
spermatogenesis GO:0007283 99 0.016
response to corticosteroid GO:0031960 235 0.016
regulation of hormone levels GO:0010817 187 0.016
divalent metal ion transport GO:0070838 132 0.016
male gamete generation GO:0048232 99 0.016
motor neuron axon guidance GO:0008045 1 0.016
positive regulation of intracellular signal transduction GO:1902533 138 0.015
response to extracellular stimulus GO:0009991 380 0.015
lipid metabolic process GO:0006629 283 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
regulation of muscle contraction GO:0006937 53 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
sensory perception GO:0007600 101 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
appendage morphogenesis GO:0035107 4 0.015
regulation of cell projection organization GO:0031344 175 0.015
cell cycle GO:0007049 101 0.015
cellular response to external stimulus GO:0071496 118 0.015
striated muscle contraction GO:0006941 44 0.015
negative regulation of secretion GO:0051048 82 0.015
eye development GO:0001654 50 0.015
secretion GO:0046903 307 0.015
mesoderm development GO:0007498 2 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
camera type eye morphogenesis GO:0048593 2 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
epithelial cell differentiation GO:0030855 71 0.014
embryonic pattern specification GO:0009880 1 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
cellular response to steroid hormone stimulus GO:0071383 93 0.014
cellular macromolecule localization GO:0070727 122 0.014
maintenance of location GO:0051235 17 0.014
calcium ion transmembrane transport GO:0070588 70 0.014
sensory organ development GO:0007423 74 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
regulation of epithelial cell proliferation GO:0050678 49 0.014
embryonic appendage morphogenesis GO:0035113 4 0.014
negative regulation of signaling GO:0023057 157 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
neuronal action potential GO:0019228 35 0.014
positive regulation of cellular catabolic process GO:0031331 71 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
regulation of peptide transport GO:0090087 87 0.014
regulation of blood circulation GO:1903522 110 0.014
embryonic skeletal system development GO:0048706 3 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
regulation of kinase activity GO:0043549 117 0.013
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.013
regulation of ion transport GO:0043269 245 0.013
response to alkaloid GO:0043279 132 0.013
regulation of anatomical structure size GO:0090066 135 0.013
secretion by cell GO:0032940 248 0.013
carboxylic acid metabolic process GO:0019752 289 0.013
biological adhesion GO:0022610 110 0.013
calcium ion transport GO:0006816 131 0.013
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.013
regulation of catabolic process GO:0009894 113 0.013
organophosphate catabolic process GO:0046434 148 0.013
proteolysis GO:0006508 175 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
cellular protein localization GO:0034613 122 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
ion homeostasis GO:0050801 212 0.013
oxidation reduction process GO:0055114 304 0.013
regulation of behavior GO:0050795 61 0.013
muscle contraction GO:0006936 88 0.013
cell motility GO:0048870 202 0.013
camera type eye development GO:0043010 48 0.013
response to oxidative stress GO:0006979 186 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
single organism biosynthetic process GO:0044711 342 0.013
cell activation GO:0001775 97 0.012
chemotaxis GO:0006935 66 0.012
cell adhesion GO:0007155 110 0.012
response to testosterone GO:0033574 55 0.012
developmental growth involved in morphogenesis GO:0060560 33 0.012
carbohydrate metabolic process GO:0005975 130 0.012
regulation of protein kinase activity GO:0045859 105 0.012
response to vitamin GO:0033273 131 0.012
cytoplasmic transport GO:0016482 115 0.012
development of primary female sexual characteristics GO:0046545 56 0.012
membrane organization GO:0061024 94 0.012
positive regulation of protein modification process GO:0031401 142 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
response to monosaccharide GO:0034284 159 0.012
positive regulation of synaptic transmission GO:0050806 62 0.012
muscle structure development GO:0061061 87 0.012
response to inorganic substance GO:0010035 377 0.012
intracellular transport GO:0046907 185 0.012
establishment of protein localization GO:0045184 141 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
reproductive structure development GO:0048608 128 0.012
regulation of heart contraction GO:0008016 48 0.012
sequestering of metal ion GO:0051238 9 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
ovulation cycle GO:0042698 67 0.012
nucleoside metabolic process GO:0009116 179 0.012
rho protein signal transduction GO:0007266 11 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
positive regulation of transport GO:0051050 245 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
circadian rhythm GO:0007623 88 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
cellular response to oxygen levels GO:0071453 60 0.012
locomotor rhythm GO:0045475 1 0.011
single organism behavior GO:0044708 130 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
camp biosynthetic process GO:0006171 47 0.011
organ regeneration GO:0031100 101 0.011
positive regulation of organelle organization GO:0010638 48 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
regulation of actin filament based process GO:0032970 42 0.011
sequestering of calcium ion GO:0051208 8 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
cyclic nucleotide biosynthetic process GO:0009190 63 0.011
gliogenesis GO:0042063 93 0.011
limb morphogenesis GO:0035108 4 0.011
cell cycle checkpoint GO:0000075 2 0.011
cyclic nucleotide metabolic process GO:0009187 80 0.011
embryonic axis specification GO:0000578 1 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
regulation of cytoskeleton organization GO:0051493 49 0.011
cell fate determination GO:0001709 2 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
female sex differentiation GO:0046660 59 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
behavior GO:0007610 205 0.011
cell cycle process GO:0022402 57 0.011
gastrulation GO:0007369 2 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
regulation of tube size GO:0035150 89 0.010
mapk cascade GO:0000165 140 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
organic hydroxy compound transport GO:0015850 77 0.010
heart development GO:0007507 72 0.010
nucleotide catabolic process GO:0009166 139 0.010
positive regulation of catalytic activity GO:0043085 184 0.010
negative regulation of signal transduction GO:0009968 83 0.010
response to ammonium ion GO:0060359 71 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
oxoacid metabolic process GO:0043436 290 0.010
muscle tissue development GO:0060537 58 0.010
actin mediated cell contraction GO:0070252 12 0.010
peptidyl tyrosine modification GO:0018212 72 0.010
multicellular organismal signaling GO:0035637 44 0.010
cellular response to glucocorticoid stimulus GO:0071385 68 0.010
positive regulation of locomotion GO:0040017 102 0.010
organic anion transport GO:0015711 132 0.010
taxis GO:0042330 67 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010

Klhl31 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
musculoskeletal system disease DOID:17 0 0.020
nervous system disease DOID:863 0 0.012
cardiovascular system disease DOID:1287 0 0.011