Rattus norvegicus

7 known processes

Mt1a

metallothionein 1a

(Aliases: Mt,Mt1)

Mt1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
astrocyte activation GO:0048143 4 0.884
astrocyte development GO:0014002 4 0.704
glial cell development GO:0021782 19 0.393
cell activation GO:0001775 97 0.391
astrocyte differentiation GO:0048708 19 0.156
central nervous system development GO:0007417 311 0.141
glial cell differentiation GO:0010001 65 0.125
cellular response to oxygen containing compound GO:1901701 386 0.123
response to nutrient levels GO:0031667 370 0.083
programmed cell death GO:0012501 392 0.082
response to nutrient GO:0007584 248 0.078
cation transport GO:0006812 382 0.072
positive regulation of cell communication GO:0010647 271 0.068
response to peptide hormone GO:0043434 278 0.067
response to estrogen GO:0043627 232 0.066
transmembrane transport GO:0055085 412 0.065
regulation of programmed cell death GO:0043067 341 0.060
gliogenesis GO:0042063 93 0.059
response to inorganic substance GO:0010035 377 0.056
cellular amine metabolic process GO:0044106 38 0.056
regulation of protein metabolic process GO:0051246 289 0.051
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.051
response to estradiol GO:0032355 164 0.050
response to metal ion GO:0010038 253 0.048
single organism biosynthetic process GO:0044711 342 0.046
metal ion transport GO:0030001 289 0.044
response to peptide GO:1901652 292 0.041
oxoacid metabolic process GO:0043436 290 0.041
organonitrogen compound biosynthetic process GO:1901566 167 0.040
cellular amino acid metabolic process GO:0006520 107 0.039
response to mechanical stimulus GO:0009612 134 0.038
aging GO:0007568 241 0.038
response to acid chemical GO:0001101 222 0.038
cellular ketone metabolic process GO:0042180 51 0.036
organic acid metabolic process GO:0006082 292 0.036
cellular homeostasis GO:0019725 252 0.036
regulation of nucleic acid templated transcription GO:1903506 380 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
cellular catabolic process GO:0044248 295 0.033
carboxylic acid metabolic process GO:0019752 289 0.033
positive regulation of phosphate metabolic process GO:0045937 262 0.033
neuron differentiation GO:0030182 368 0.033
regulation of multicellular organismal development GO:2000026 376 0.032
cellular response to endogenous stimulus GO:0071495 377 0.032
ion transmembrane transport GO:0034220 365 0.032
regulation of apoptotic process GO:0042981 335 0.031
response to extracellular stimulus GO:0009991 380 0.031
response to tumor necrosis factor GO:0034612 56 0.031
cell projection organization GO:0030030 302 0.030
proteolysis GO:0006508 175 0.030
intracellular signal transduction GO:0035556 314 0.030
amine metabolic process GO:0009308 38 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
regulation of molecular function GO:0065009 398 0.029
head development GO:0060322 247 0.028
macromolecular complex subunit organization GO:0043933 339 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
positive regulation of developmental process GO:0051094 283 0.028
response to decreased oxygen levels GO:0036293 237 0.028
protein complex subunit organization GO:0071822 302 0.027
response to ketone GO:1901654 182 0.027
cellular response to hormone stimulus GO:0032870 247 0.027
rna metabolic process GO:0016070 406 0.027
regulation of cellular component organization GO:0051128 368 0.027
regulation of cell proliferation GO:0042127 359 0.026
reproductive process GO:0022414 372 0.026
negative regulation of molecular function GO:0044092 133 0.026
macromolecular complex assembly GO:0065003 273 0.026
anion transport GO:0006820 178 0.026
response to molecule of bacterial origin GO:0002237 194 0.026
regulation of vesicle mediated transport GO:0060627 81 0.026
cellular response to organic cyclic compound GO:0071407 202 0.025
cellular response to tumor necrosis factor GO:0071356 46 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.024
chemical homeostasis GO:0048878 292 0.024
cellular response to peptide hormone stimulus GO:0071375 120 0.024
regulation of immune system process GO:0002682 123 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
cellular response to interleukin 1 GO:0071347 37 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
protein complex biogenesis GO:0070271 263 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
regulation of phosphorylation GO:0042325 248 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
cellular ion homeostasis GO:0006873 184 0.023
homeostatic process GO:0042592 331 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
transcription from rna polymerase ii promoter GO:0006366 252 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
cellular component biogenesis GO:0044085 368 0.023
response to vitamin GO:0033273 131 0.023
neuron development GO:0048666 286 0.023
cellular component assembly GO:0022607 360 0.023
negative regulation of cell death GO:0060548 229 0.023
nucleic acid templated transcription GO:0097659 379 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
regulation of transcription dna templated GO:0006355 374 0.022
tissue development GO:0009888 252 0.022
rna biosynthetic process GO:0032774 380 0.022
regulation of cell differentiation GO:0045595 320 0.021
cellular chemical homeostasis GO:0055082 247 0.021
negative regulation of metabolic process GO:0009892 331 0.021
negative regulation of cell proliferation GO:0008285 119 0.021
cellular response to abiotic stimulus GO:0071214 85 0.021
carbohydrate derivative biosynthetic process GO:1901137 124 0.020
epithelium development GO:0060429 96 0.020
protein complex assembly GO:0006461 263 0.020
negative regulation of transport GO:0051051 136 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
nitrogen compound transport GO:0071705 229 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
cellular response to lipopolysaccharide GO:0071222 55 0.020
ion homeostasis GO:0050801 212 0.019
brain development GO:0007420 247 0.019
response to hypoxia GO:0001666 231 0.019
secretion GO:0046903 307 0.019
cellular cation homeostasis GO:0030003 180 0.019
cell cell signaling GO:0007267 335 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
response to glucocorticoid GO:0051384 223 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
regulation of cellular localization GO:0060341 263 0.019
apoptotic process GO:0006915 381 0.019
response to carbohydrate GO:0009743 183 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
multi organism reproductive process GO:0044703 262 0.018
macromolecule localization GO:0033036 252 0.018
regulation of system process GO:0044057 208 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
immune system process GO:0002376 204 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
regulation of cell development GO:0060284 263 0.018
regulation of phosphorus metabolic process GO:0051174 349 0.018
protein oligomerization GO:0051259 191 0.018
response to external biotic stimulus GO:0043207 221 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
cell growth GO:0016049 104 0.017
positive regulation of signaling GO:0023056 270 0.017
positive regulation of molecular function GO:0044093 230 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
cardiovascular system development GO:0072358 134 0.017
regulation of neurogenesis GO:0050767 247 0.017
transcription dna templated GO:0006351 377 0.017
cellular response to insulin stimulus GO:0032869 81 0.017
regulation of protein maturation GO:1903317 50 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
organic substance catabolic process GO:1901575 316 0.016
regulation of endopeptidase activity GO:0052548 51 0.016
response to oxidative stress GO:0006979 186 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
response to alkaloid GO:0043279 132 0.016
response to oxygen levels GO:0070482 265 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
cellular component movement GO:0006928 248 0.016
response to reactive oxygen species GO:0000302 120 0.016
defense response GO:0006952 194 0.015
response to bacterium GO:0009617 200 0.015
ras protein signal transduction GO:0007265 29 0.015
response to monosaccharide GO:0034284 159 0.015
regulation of homeostatic process GO:0032844 101 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
cellular response to lipid GO:0071396 201 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
response to lipopolysaccharide GO:0032496 191 0.015
regulation of catalytic activity GO:0050790 304 0.015
organic anion transport GO:0015711 132 0.015
growth GO:0040007 165 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
cation homeostasis GO:0055080 195 0.015
positive regulation of gene expression GO:0010628 244 0.015
regulation of nervous system development GO:0051960 264 0.015
organelle organization GO:0006996 266 0.015
nucleotide metabolic process GO:0009117 279 0.014
regulation of secretion GO:0051046 224 0.014
positive regulation of nervous system development GO:0051962 178 0.014
metal ion homeostasis GO:0055065 186 0.014
positive regulation of angiogenesis GO:0045766 28 0.014
regulation of hydrolase activity GO:0051336 143 0.014
sex differentiation GO:0007548 113 0.014
regulation of cell projection organization GO:0031344 175 0.014
oxidation reduction process GO:0055114 304 0.014
response to magnesium ion GO:0032026 20 0.014
axis specification GO:0009798 4 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
circulatory system process GO:0003013 183 0.014
neurological system process GO:0050877 219 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
regulation of cell growth GO:0001558 85 0.014
regulation of peptidase activity GO:0052547 55 0.014
anatomical structure morphogenesis GO:0009653 298 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
anion transmembrane transport GO:0098656 77 0.014
response to corticosteroid GO:0031960 235 0.014
secretion by cell GO:0032940 248 0.014
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.014
transformation of host cell by virus GO:0019087 4 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
negative regulation of catalytic activity GO:0043086 103 0.013
response to amino acid GO:0043200 75 0.013
response to wounding GO:0009611 254 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
cellular response to stress GO:0033554 269 0.013
positive regulation of cell development GO:0010720 176 0.013
response to other organism GO:0051707 220 0.013
sexual reproduction GO:0019953 148 0.013
response to glucose GO:0009749 136 0.013
regulation of ras protein signal transduction GO:0046578 45 0.013
carboxylic acid transport GO:0046942 115 0.013
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 1 0.013
positive regulation of transport GO:0051050 245 0.013
cellular response to biotic stimulus GO:0071216 59 0.013
catabolic process GO:0009056 351 0.013
inflammatory response GO:0006954 150 0.013
regulation of growth GO:0040008 105 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
purine containing compound metabolic process GO:0072521 253 0.013
regulation of rna metabolic process GO:0051252 391 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
response to interleukin 1 GO:0070555 55 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
response to growth factor GO:0070848 189 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
transmission of nerve impulse GO:0019226 42 0.013
negative regulation of neuron apoptotic process GO:0043524 45 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
negative regulation of gene expression GO:0010629 199 0.012
intracellular transport GO:0046907 185 0.012
activation of cysteine type endopeptidase activity GO:0097202 4 0.012
response to hexose GO:0009746 144 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
cellular response to nutrient levels GO:0031669 60 0.012
positive regulation of signal transduction GO:0009967 175 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
divalent metal ion transport GO:0070838 132 0.012
neuron death GO:0070997 127 0.012
single organism catabolic process GO:0044712 283 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
regulation of protein modification process GO:0031399 194 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
regulation of membrane potential GO:0042391 110 0.012
endocytosis GO:0006897 84 0.012
regulation of neuron projection development GO:0010975 161 0.012
synaptic transmission GO:0007268 235 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
mapk cascade GO:0000165 140 0.012
coenzyme metabolic process GO:0006732 86 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
reproduction GO:0000003 245 0.011
blood circulation GO:0008015 183 0.011
regulation of secretion by cell GO:1903530 208 0.011
negative regulation of developmental process GO:0051093 125 0.011
response to biotic stimulus GO:0009607 226 0.011
renal system development GO:0072001 67 0.011
protein phosphorylation GO:0006468 345 0.011
regulation of hormone levels GO:0010817 187 0.011
calcium ion transport GO:0006816 131 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
multicellular organism reproduction GO:0032504 233 0.011
protein processing GO:0016485 68 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
endothelium development GO:0003158 12 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
regulation of neuron death GO:1901214 115 0.011
carbohydrate homeostasis GO:0033500 75 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
protein localization GO:0008104 191 0.011
response to fluoride GO:1902617 3 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
cell projection morphogenesis GO:0048858 123 0.011
embryonic pattern specification GO:0009880 1 0.011
tetrapyrrole metabolic process GO:0033013 11 0.010
negative regulation of cell communication GO:0010648 158 0.010
protein maturation GO:0051604 68 0.010
biological adhesion GO:0022610 110 0.010
carbohydrate metabolic process GO:0005975 130 0.010
response to toxic substance GO:0009636 133 0.010
regulation of proteolysis GO:0030162 66 0.010
regulation of ion transport GO:0043269 245 0.010
cellular component morphogenesis GO:0032989 155 0.010
urogenital system development GO:0001655 78 0.010
regulation of small gtpase mediated signal transduction GO:0051056 48 0.010
regulation of cellular protein metabolic process GO:0032268 267 0.010
cell type specific apoptotic process GO:0097285 134 0.010
lipid storage GO:0019915 1 0.010
regulation of smooth muscle cell proliferation GO:0048660 75 0.010
cellular amino acid biosynthetic process GO:0008652 32 0.010
carbohydrate derivative metabolic process GO:1901135 346 0.010
response to cytokine GO:0034097 215 0.010
positive regulation of cell death GO:0010942 184 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
negative regulation of secretion by cell GO:1903531 72 0.010
dna metabolic process GO:0006259 96 0.010
response to purine containing compound GO:0014074 126 0.010
rhythmic process GO:0048511 156 0.010
positive regulation of response to stimulus GO:0048584 285 0.010
cofactor metabolic process GO:0051186 95 0.010
cytoplasmic transport GO:0016482 115 0.010

Mt1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
nervous system disease DOID:863 0 0.053
central nervous system disease DOID:331 0 0.020
musculoskeletal system disease DOID:17 0 0.020
disease of metabolism DOID:0014667 0 0.019
inherited metabolic disorder DOID:655 0 0.018
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
brain disease DOID:936 0 0.014
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011