Rattus norvegicus

0 known processes

Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

(Aliases: MGC72599)

Plekha4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.109
regulation of transcription dna templated GO:0006355 374 0.083
response to inorganic substance GO:0010035 377 0.061
programmed cell death GO:0012501 392 0.060
rna biosynthetic process GO:0032774 380 0.059
negative regulation of cell death GO:0060548 229 0.058
regulation of programmed cell death GO:0043067 341 0.054
rna metabolic process GO:0016070 406 0.052
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.051
transcription dna templated GO:0006351 377 0.050
response to nutrient levels GO:0031667 370 0.047
transmembrane transport GO:0055085 412 0.045
nucleic acid templated transcription GO:0097659 379 0.045
cation transport GO:0006812 382 0.044
regulation of rna metabolic process GO:0051252 391 0.044
oxoacid metabolic process GO:0043436 290 0.044
regulation of protein metabolic process GO:0051246 289 0.044
response to peptide hormone GO:0043434 278 0.044
regulation of apoptotic process GO:0042981 335 0.044
cellular response to oxygen containing compound GO:1901701 386 0.043
reproductive process GO:0022414 372 0.043
carboxylic acid metabolic process GO:0019752 289 0.042
transcription from rna polymerase ii promoter GO:0006366 252 0.041
response to external biotic stimulus GO:0043207 221 0.040
positive regulation of response to stimulus GO:0048584 285 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
regulation of molecular function GO:0065009 398 0.039
chemical homeostasis GO:0048878 292 0.038
regulation of cellular amine metabolic process GO:0033238 8 0.037
positive regulation of gene expression GO:0010628 244 0.037
regulation of cell proliferation GO:0042127 359 0.037
single organism biosynthetic process GO:0044711 342 0.037
response to lipopolysaccharide GO:0032496 191 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.035
cell motility GO:0048870 202 0.035
cellular component movement GO:0006928 248 0.034
regulation of cell differentiation GO:0045595 320 0.034
regulation of rna biosynthetic process GO:2001141 381 0.034
cellular amine metabolic process GO:0044106 38 0.033
positive regulation of cell communication GO:0010647 271 0.033
single organism reproductive process GO:0044702 297 0.033
response to extracellular stimulus GO:0009991 380 0.033
cellular response to nitrogen compound GO:1901699 210 0.032
cellular chemical homeostasis GO:0055082 247 0.032
amine metabolic process GO:0009308 38 0.032
positive regulation of biosynthetic process GO:0009891 319 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
response to bacterium GO:0009617 200 0.032
cellular amino acid metabolic process GO:0006520 107 0.031
response to estrogen GO:0043627 232 0.031
homeostatic process GO:0042592 331 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
cellular response to peptide hormone stimulus GO:0071375 120 0.031
response to glucocorticoid GO:0051384 223 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
positive regulation of cell proliferation GO:0008284 249 0.031
regulation of intracellular signal transduction GO:1902531 218 0.031
regulation of signal transduction GO:0009966 318 0.031
rhythmic process GO:0048511 156 0.030
response to peptide GO:1901652 292 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
organophosphate metabolic process GO:0019637 370 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
positive regulation of intracellular signal transduction GO:1902533 138 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.029
catabolic process GO:0009056 351 0.028
cation homeostasis GO:0055080 195 0.028
cellular response to hormone stimulus GO:0032870 247 0.028
negative regulation of metabolic process GO:0009892 331 0.028
response to carbohydrate GO:0009743 183 0.028
secretion by cell GO:0032940 248 0.028
regulation of catalytic activity GO:0050790 304 0.028
ion homeostasis GO:0050801 212 0.028
immune system process GO:0002376 204 0.028
cellular catabolic process GO:0044248 295 0.028
response to other organism GO:0051707 220 0.027
cellular homeostasis GO:0019725 252 0.027
response to biotic stimulus GO:0009607 226 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
cellular cation homeostasis GO:0030003 180 0.026
response to corticosteroid GO:0031960 235 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
cellular ion homeostasis GO:0006873 184 0.026
response to acid chemical GO:0001101 222 0.026
regulation of cellular component organization GO:0051128 368 0.026
protein phosphorylation GO:0006468 345 0.026
positive regulation of developmental process GO:0051094 283 0.026
response to radiation GO:0009314 137 0.026
apoptotic process GO:0006915 381 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
cellular component biogenesis GO:0044085 368 0.025
cellular response to cytokine stimulus GO:0071345 127 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
localization of cell GO:0051674 202 0.025
secretion GO:0046903 307 0.025
cellular ketone metabolic process GO:0042180 51 0.024
metal ion transport GO:0030001 289 0.024
response to molecule of bacterial origin GO:0002237 194 0.024
lipid metabolic process GO:0006629 283 0.024
regulation of response to stress GO:0080134 126 0.023
cellular response to stress GO:0033554 269 0.023
reproduction GO:0000003 245 0.023
g protein coupled receptor signaling pathway GO:0007186 242 0.023
cell migration GO:0016477 197 0.023
response to insulin GO:0032868 133 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
tissue development GO:0009888 252 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
positive regulation of signaling GO:0023056 270 0.023
cellular component assembly GO:0022607 360 0.023
inorganic ion transmembrane transport GO:0098660 229 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
divalent inorganic cation homeostasis GO:0072507 165 0.022
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.022
aging GO:0007568 241 0.022
organelle organization GO:0006996 266 0.022
negative regulation of programmed cell death GO:0043069 183 0.021
single organism catabolic process GO:0044712 283 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
regulation of hormone levels GO:0010817 187 0.021
regulation of cellular component movement GO:0051270 150 0.021
response to oxidative stress GO:0006979 186 0.021
regulation of phosphorylation GO:0042325 248 0.021
ion transmembrane transport GO:0034220 365 0.021
regulation of immune system process GO:0002682 123 0.021
cellular response to peptide GO:1901653 133 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
response to growth factor GO:0070848 189 0.020
regulation of protein modification process GO:0031399 194 0.020
cation transmembrane transport GO:0098655 263 0.020
positive regulation of transport GO:0051050 245 0.020
macromolecular complex assembly GO:0065003 273 0.020
inorganic cation transmembrane transport GO:0098662 202 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.020
response to cytokine GO:0034097 215 0.020
locomotion GO:0040011 237 0.020
macromolecule localization GO:0033036 252 0.020
ras protein signal transduction GO:0007265 29 0.020
multicellular organism reproduction GO:0032504 233 0.020
single organism intracellular transport GO:1902582 166 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
positive regulation of phosphorylation GO:0042327 177 0.019
defense response GO:0006952 194 0.019
intracellular transport GO:0046907 185 0.019
neuron projection development GO:0031175 273 0.019
metal ion homeostasis GO:0055065 186 0.019
nucleotide metabolic process GO:0009117 279 0.019
response to metal ion GO:0010038 253 0.019
regulation of metal ion transport GO:0010959 118 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
behavior GO:0007610 205 0.019
cellular response to endogenous stimulus GO:0071495 377 0.019
response to nutrient GO:0007584 248 0.019
single organism organelle organization GO:1902589 180 0.019
response to wounding GO:0009611 254 0.019
cell projection organization GO:0030030 302 0.019
organic acid metabolic process GO:0006082 292 0.018
regulation of cell development GO:0060284 263 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
monovalent inorganic cation transport GO:0015672 172 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
cell cell signaling GO:0007267 335 0.018
cellular lipid metabolic process GO:0044255 208 0.018
central nervous system development GO:0007417 311 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
response to ethanol GO:0045471 162 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.017
organic substance catabolic process GO:1901575 316 0.017
wound healing GO:0042060 122 0.017
positive regulation of signal transduction GO:0009967 175 0.017
immune response GO:0006955 104 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
regeneration GO:0031099 163 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
calcium ion homeostasis GO:0055074 162 0.017
purine containing compound metabolic process GO:0072521 253 0.016
positive regulation of cell development GO:0010720 176 0.016
regulation of system process GO:0044057 208 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
negative regulation of innate immune response GO:0045824 4 0.016
divalent inorganic cation transport GO:0072511 134 0.016
proteolysis GO:0006508 175 0.016
positive regulation of nervous system development GO:0051962 178 0.016
response to hexose GO:0009746 144 0.016
regulation of hormone secretion GO:0046883 106 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
regulation of cell motility GO:2000145 131 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
regulation of response to external stimulus GO:0032101 106 0.016
regulation of cellular localization GO:0060341 263 0.016
protein complex assembly GO:0006461 263 0.016
multi organism reproductive process GO:0044703 262 0.015
nitrogen compound transport GO:0071705 229 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
neuron differentiation GO:0030182 368 0.015
protein complex subunit organization GO:0071822 302 0.015
vesicle mediated transport GO:0016192 181 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
regulation of cell migration GO:0030334 128 0.015
amide transport GO:0042886 105 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
cellular response to lipid GO:0071396 201 0.015
neuron development GO:0048666 286 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
negative regulation of secretion GO:0051048 82 0.015
response to monosaccharide GO:0034284 159 0.015
regulation of nervous system development GO:0051960 264 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
regulation of response to wounding GO:1903034 69 0.014
positive regulation of molecular function GO:0044093 230 0.014
protein complex biogenesis GO:0070271 263 0.014
aromatic compound catabolic process GO:0019439 168 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
response to glucose GO:0009749 136 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
inflammatory response GO:0006954 150 0.014
negative regulation of gene expression GO:0010629 199 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
response to vitamin GO:0033273 131 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
neurological system process GO:0050877 219 0.014
regulation of ion transport GO:0043269 245 0.014
sodium ion transport GO:0006814 82 0.014
protein localization GO:0008104 191 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
response to oxygen levels GO:0070482 265 0.014
blood vessel development GO:0001568 69 0.014
regulation of locomotion GO:0040012 148 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
synaptic transmission GO:0007268 235 0.013
oxidation reduction process GO:0055114 304 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
regulation of synaptic transmission GO:0050804 141 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
signal release GO:0023061 145 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
regulation of defense response GO:0031347 68 0.013
cell activation GO:0001775 97 0.013
regulation of secretion GO:0051046 224 0.013
reproductive system development GO:0061458 128 0.013
small molecule biosynthetic process GO:0044283 124 0.013
cellular metal ion homeostasis GO:0006875 172 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
actin filament based process GO:0030029 86 0.012
nucleoside catabolic process GO:0009164 126 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
regulation of neurogenesis GO:0050767 247 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
hormone transport GO:0009914 121 0.012
regulation of neuron projection development GO:0010975 161 0.012
single organism behavior GO:0044708 130 0.012
sexual reproduction GO:0019953 148 0.012
anion transport GO:0006820 178 0.012
regulation of hydrolase activity GO:0051336 143 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
gastrulation GO:0007369 2 0.012
protein oligomerization GO:0051259 191 0.012
regulation of membrane potential GO:0042391 110 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
negative regulation of transport GO:0051051 136 0.012
b cell differentiation GO:0030183 2 0.012
eye morphogenesis GO:0048592 4 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
response to ketone GO:1901654 182 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
positive regulation of protein modification process GO:0031401 142 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
divalent metal ion transport GO:0070838 132 0.011
organophosphate catabolic process GO:0046434 148 0.011
neuronal action potential GO:0019228 35 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
development of primary female sexual characteristics GO:0046545 56 0.011
heterocycle catabolic process GO:0046700 167 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
reproductive structure development GO:0048608 128 0.011
axis specification GO:0009798 4 0.011
cell morphogenesis GO:0000902 142 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
mapk cascade GO:0000165 140 0.011
response to estradiol GO:0032355 164 0.011
circulatory system process GO:0003013 183 0.011
negative regulation of molecular function GO:0044092 133 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
purine containing compound catabolic process GO:0072523 138 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
establishment of protein localization GO:0045184 141 0.011
regulation of secretion by cell GO:1903530 208 0.011
circulatory system development GO:0072359 134 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
positive regulation of cell death GO:0010942 184 0.011
adult locomotory behavior GO:0008344 4 0.011
multicellular organismal signaling GO:0035637 44 0.011
skeletal system development GO:0001501 41 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
response to decreased oxygen levels GO:0036293 237 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
cellular component morphogenesis GO:0032989 155 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
protein homooligomerization GO:0051260 91 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
organic anion transport GO:0015711 132 0.010
membrane organization GO:0061024 94 0.010
nucleoside metabolic process GO:0009116 179 0.010
carbohydrate metabolic process GO:0005975 130 0.010
sodium ion transmembrane transport GO:0035725 67 0.010
ossification GO:0001503 70 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
negative regulation of secretion by cell GO:1903531 72 0.010

Plekha4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
myopathy DOID:423 0 0.020
muscular disease DOID:0080000 0 0.020
musculoskeletal system disease DOID:17 0 0.020
muscle tissue disease DOID:66 0 0.020
sensory system disease DOID:0050155 0 0.011
disease of metabolism DOID:0014667 0 0.010
eye and adnexa disease DOID:1492 0 0.010