Rattus norvegicus

0 known processes

Plekha6

pleckstrin homology domain containing, family A member 6

(Aliases: RGD1564395)

Plekha6 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of molecular function GO:0065009 398 0.090
regulation of phosphate metabolic process GO:0019220 349 0.087
positive regulation of phosphorus metabolic process GO:0010562 262 0.076
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.063
cellular component biogenesis GO:0044085 368 0.060
regulation of catalytic activity GO:0050790 304 0.058
cellular component assembly GO:0022607 360 0.056
protein complex biogenesis GO:0070271 263 0.054
regulation of rna biosynthetic process GO:2001141 381 0.053
protein complex assembly GO:0006461 263 0.047
intracellular signal transduction GO:0035556 314 0.047
regulation of protein metabolic process GO:0051246 289 0.046
positive regulation of gtpase activity GO:0043547 47 0.043
regulation of nucleotide metabolic process GO:0006140 117 0.043
positive regulation of catalytic activity GO:0043085 184 0.043
protein phosphorylation GO:0006468 345 0.042
positive regulation of molecular function GO:0044093 230 0.041
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
response to inorganic substance GO:0010035 377 0.038
positive regulation of biosynthetic process GO:0009891 319 0.037
regulation of canonical wnt signaling pathway GO:0060828 4 0.036
regulation of hydrolase activity GO:0051336 143 0.035
regulation of cellular amino acid metabolic process GO:0006521 2 0.035
cellular response to vitamin e GO:0071306 3 0.035
transcription dna templated GO:0006351 377 0.035
purine ribonucleotide metabolic process GO:0009150 227 0.034
cellular amino acid metabolic process GO:0006520 107 0.034
protein complex subunit organization GO:0071822 302 0.034
nucleoside metabolic process GO:0009116 179 0.034
glycosyl compound metabolic process GO:1901657 182 0.033
positive regulation of nucleoside metabolic process GO:0045979 55 0.033
ras protein signal transduction GO:0007265 29 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.032
regulation of cellular protein metabolic process GO:0032268 267 0.032
purine nucleoside catabolic process GO:0006152 124 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.030
ion transmembrane transport GO:0034220 365 0.030
catabolic process GO:0009056 351 0.030
nucleotide metabolic process GO:0009117 279 0.029
regulation of rna metabolic process GO:0051252 391 0.029
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.029
positive regulation of hydrolase activity GO:0051345 86 0.029
cation transmembrane transport GO:0098655 263 0.029
rna biosynthetic process GO:0032774 380 0.029
macromolecular complex subunit organization GO:0043933 339 0.028
actin filament based process GO:0030029 86 0.028
intracellular transport GO:0046907 185 0.027
gtp catabolic process GO:0006184 71 0.027
regulation of cellular component organization GO:0051128 368 0.027
cellular component movement GO:0006928 248 0.027
purine containing compound metabolic process GO:0072521 253 0.027
nucleoside phosphate catabolic process GO:1901292 140 0.026
regulation of purine nucleotide metabolic process GO:1900542 115 0.026
regulation of catabolic process GO:0009894 113 0.026
regulation of telomerase activity GO:0051972 2 0.026
purine nucleotide metabolic process GO:0006163 229 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
positive regulation of nucleotide metabolic process GO:0045981 91 0.025
aromatic compound catabolic process GO:0019439 168 0.025
regulation of transcription dna templated GO:0006355 374 0.025
inorganic cation transmembrane transport GO:0098662 202 0.025
nucleic acid templated transcription GO:0097659 379 0.024
organic acid metabolic process GO:0006082 292 0.024
positive regulation of gtp catabolic process GO:0033126 48 0.024
ribonucleoside catabolic process GO:0042454 126 0.024
carboxylic acid metabolic process GO:0019752 289 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
purine nucleoside triphosphate catabolic process GO:0009146 122 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
guanosine containing compound catabolic process GO:1901069 71 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.023
amine metabolic process GO:0009308 38 0.023
single organism catabolic process GO:0044712 283 0.023
regulation of protein modification process GO:0031399 194 0.023
negative regulation of metabolic process GO:0009892 331 0.023
central nervous system development GO:0007417 311 0.023
positive regulation of nucleotide catabolic process GO:0030813 53 0.023
cation transport GO:0006812 382 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
ribonucleoside triphosphate catabolic process GO:0009203 122 0.022
regulation of cell differentiation GO:0045595 320 0.022
positive regulation of gene expression GO:0010628 244 0.022
regulation of nucleoside metabolic process GO:0009118 66 0.022
regulation of gtpase activity GO:0043087 57 0.022
macromolecular complex assembly GO:0065003 273 0.021
regulation of nervous system development GO:0051960 264 0.021
regulation of neuron projection development GO:0010975 161 0.021
macromolecule localization GO:0033036 252 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
neuron projection development GO:0031175 273 0.021
positive regulation of cellular catabolic process GO:0031331 71 0.021
cellular amine metabolic process GO:0044106 38 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.020
programmed cell death GO:0012501 392 0.020
cellular macromolecular complex assembly GO:0034622 58 0.020
nucleoside triphosphate metabolic process GO:0009141 144 0.020
response to estrogen GO:0043627 232 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.020
regulation of phosphorylation GO:0042325 248 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
nucleoside triphosphate catabolic process GO:0009143 123 0.020
cellular protein complex assembly GO:0043623 44 0.020
regulation of cell projection organization GO:0031344 175 0.019
regulation of signal transduction GO:0009966 318 0.019
regulation of purine nucleotide catabolic process GO:0033121 65 0.019
cellular response to stress GO:0033554 269 0.019
cell projection morphogenesis GO:0048858 123 0.019
positive regulation of ras gtpase activity GO:0032320 28 0.019
regulation of cellular catabolic process GO:0031329 101 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
heterocycle catabolic process GO:0046700 167 0.018
positive regulation of catabolic process GO:0009896 78 0.018
nucleoside catabolic process GO:0009164 126 0.018
regulation of gtp catabolic process GO:0033124 58 0.018
cellular protein localization GO:0034613 122 0.018
cytoskeleton organization GO:0007010 111 0.018
regulation of cell development GO:0060284 263 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
gtp metabolic process GO:0046039 72 0.018
positive regulation of cell death GO:0010942 184 0.018
metal ion transport GO:0030001 289 0.017
regulation of cell proliferation GO:0042127 359 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
vesicle mediated transport GO:0016192 181 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
regulation of rab protein signal transduction GO:0032483 3 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
guanosine containing compound metabolic process GO:1901068 74 0.017
single organism biosynthetic process GO:0044711 342 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
reproductive process GO:0022414 372 0.017
regulation of neurogenesis GO:0050767 247 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
single organism cellular localization GO:1902580 102 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
ribonucleotide catabolic process GO:0009261 136 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
response to acid chemical GO:0001101 222 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
nucleotide catabolic process GO:0009166 139 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
multi organism reproductive process GO:0044703 262 0.016
transmembrane transport GO:0055085 412 0.016
single organism reproductive process GO:0044702 297 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
brain development GO:0007420 247 0.016
neuron differentiation GO:0030182 368 0.016
inflammatory response GO:0006954 150 0.016
regulation of mesenchymal cell proliferation GO:0010464 4 0.016
olfactory bulb interneuron differentiation GO:0021889 1 0.015
oxoacid metabolic process GO:0043436 290 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
rna metabolic process GO:0016070 406 0.015
mesenchymal cell proliferation GO:0010463 4 0.015
cytoplasmic transport GO:0016482 115 0.015
cellular catabolic process GO:0044248 295 0.015
aging GO:0007568 241 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
cerebral cortex tangential migration GO:0021800 1 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
single organism organelle organization GO:1902589 180 0.015
urogenital system development GO:0001655 78 0.015
cell motility GO:0048870 202 0.014
head development GO:0060322 247 0.014
protein heterooligomerization GO:0051291 89 0.014
cell projection organization GO:0030030 302 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.014
wnt signaling pathway GO:0016055 17 0.014
reproductive structure development GO:0048608 128 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
regulation of nucleotide catabolic process GO:0030811 65 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
sequestering of metal ion GO:0051238 9 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
cellular component morphogenesis GO:0032989 155 0.014
negative regulation of cellular metabolic process GO:0031324 281 0.014
growth GO:0040007 165 0.014
cell migration GO:0016477 197 0.014
actin filament based movement GO:0030048 16 0.014
sex differentiation GO:0007548 113 0.014
response to cytokine GO:0034097 215 0.014
cell part morphogenesis GO:0032990 123 0.014
cell cell signaling GO:0007267 335 0.014
locomotion GO:0040011 237 0.014
protein oligomerization GO:0051259 191 0.014
response to hypoxia GO:0001666 231 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
establishment of tissue polarity GO:0007164 2 0.013
formation of primary germ layer GO:0001704 1 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
proteolysis GO:0006508 175 0.013
mapk cascade GO:0000165 140 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
peptidyl amino acid modification GO:0018193 126 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
response to oxygen levels GO:0070482 265 0.013
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.013
cell communication involved in cardiac conduction GO:0086065 2 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
multicellular organism reproduction GO:0032504 233 0.013
single organism intracellular transport GO:1902582 166 0.013
cell adhesion GO:0007155 110 0.013
defense response GO:0006952 194 0.013
sequestering of calcium ion GO:0051208 8 0.013
organelle organization GO:0006996 266 0.013
organic substance catabolic process GO:1901575 316 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
blood circulation GO:0008015 183 0.013
gastrulation GO:0007369 2 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
regulation of anatomical structure size GO:0090066 135 0.012
carboxylic acid biosynthetic process GO:0046394 83 0.012
response to decreased oxygen levels GO:0036293 237 0.012
response to extracellular stimulus GO:0009991 380 0.012
protein tetramerization GO:0051262 38 0.012
peptidyl tyrosine phosphorylation GO:0018108 72 0.012
response to peptide hormone GO:0043434 278 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
cardiac conduction GO:0061337 2 0.012
homeostatic process GO:0042592 331 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of kinase activity GO:0043549 117 0.012
regulation of protein localization GO:0032880 81 0.012
tissue development GO:0009888 252 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
neuron projection morphogenesis GO:0048812 122 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
cellular response to oxygen containing compound GO:1901701 386 0.012
cellular ketone metabolic process GO:0042180 51 0.012
negative regulation of gene expression GO:0010629 199 0.012
cellular response to external stimulus GO:0071496 118 0.012
protein localization GO:0008104 191 0.012
regulation of ras gtpase activity GO:0032318 32 0.011
cellular potassium ion transport GO:0071804 72 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
reproduction GO:0000003 245 0.011
cell morphogenesis GO:0000902 142 0.011
protein polymerization GO:0051258 22 0.011
regulation of cell migration GO:0030334 128 0.011
response to ketone GO:1901654 182 0.011
action potential GO:0001508 54 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
gonad development GO:0008406 104 0.011
dendrite development GO:0016358 72 0.011
regulation of transmembrane transport GO:0034762 122 0.011
circulatory system process GO:0003013 183 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
dephosphorylation GO:0016311 98 0.011
biological adhesion GO:0022610 110 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
cell cycle checkpoint GO:0000075 2 0.010
localization of cell GO:0051674 202 0.010
muscle system process GO:0003012 115 0.010
developmental process involved in reproduction GO:0003006 159 0.010
melanocyte differentiation GO:0030318 2 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
anterior posterior pattern specification GO:0009952 1 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
cellular chemical homeostasis GO:0055082 247 0.010
regulation of transferase activity GO:0051338 123 0.010
regulation of muscle system process GO:0090257 79 0.010
renal system development GO:0072001 67 0.010
cellular homeostasis GO:0019725 252 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
transcription from rna polymerase ii promoter GO:0006366 252 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
spindle organization GO:0007051 2 0.010
mesoderm development GO:0007498 2 0.010
negative regulation of response to stimulus GO:0048585 155 0.010

Plekha6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
nervous system disease DOID:863 0 0.049
sensory system disease DOID:0050155 0 0.025
retinal disease DOID:5679 0 0.019
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.019
central nervous system disease DOID:331 0 0.014
brain disease DOID:936 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
disease of metabolism DOID:0014667 0 0.013