Rattus norvegicus

0 known processes

Plekha8

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8

(Aliases: RGD1563940)

Plekha8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.071
cellular component biogenesis GO:0044085 368 0.060
transcription dna templated GO:0006351 377 0.053
regulation of rna biosynthetic process GO:2001141 381 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.046
regulation of multicellular organismal development GO:2000026 376 0.043
homeostatic process GO:0042592 331 0.041
rna biosynthetic process GO:0032774 380 0.040
regulation of cell differentiation GO:0045595 320 0.039
cell projection organization GO:0030030 302 0.038
synaptic growth at neuromuscular junction GO:0051124 1 0.038
positive regulation of biosynthetic process GO:0009891 319 0.037
neuron differentiation GO:0030182 368 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
organelle organization GO:0006996 266 0.036
central nervous system development GO:0007417 311 0.035
regulation of transcription dna templated GO:0006355 374 0.034
regulation of rna metabolic process GO:0051252 391 0.034
regulation of cellular component organization GO:0051128 368 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.033
regulation of nervous system development GO:0051960 264 0.033
positive regulation of cellular component organization GO:0051130 200 0.033
macromolecular complex subunit organization GO:0043933 339 0.032
cellular component movement GO:0006928 248 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.032
cellular component morphogenesis GO:0032989 155 0.032
catabolic process GO:0009056 351 0.031
transcription from rna polymerase ii promoter GO:0006366 252 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
negative regulation of metabolic process GO:0009892 331 0.030
regulation of neurogenesis GO:0050767 247 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
negative regulation of multicellular organismal process GO:0051241 203 0.029
organic acid metabolic process GO:0006082 292 0.028
response to peptide GO:1901652 292 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
protein phosphorylation GO:0006468 345 0.028
oxoacid metabolic process GO:0043436 290 0.027
regulation of molecular function GO:0065009 398 0.027
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.026
response to nutrient levels GO:0031667 370 0.026
neuron development GO:0048666 286 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
regulation of neuron differentiation GO:0045664 208 0.026
apoptotic process GO:0006915 381 0.026
cellular component assembly GO:0022607 360 0.025
nucleic acid templated transcription GO:0097659 379 0.025
organic substance catabolic process GO:1901575 316 0.025
positive regulation of rna metabolic process GO:0051254 203 0.025
protein complex assembly GO:0006461 263 0.025
single organism catabolic process GO:0044712 283 0.024
macromolecule localization GO:0033036 252 0.024
Human
cellular catabolic process GO:0044248 295 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
organophosphate metabolic process GO:0019637 370 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
single organism reproductive process GO:0044702 297 0.024
intracellular signal transduction GO:0035556 314 0.023
nucleotide metabolic process GO:0009117 279 0.023
macromolecular complex assembly GO:0065003 273 0.023
cell part morphogenesis GO:0032990 123 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
cell cell signaling GO:0007267 335 0.022
positive regulation of gene expression GO:0010628 244 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
locomotion GO:0040011 237 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
protein complex biogenesis GO:0070271 263 0.022
carboxylic acid metabolic process GO:0019752 289 0.021
cellular response to stress GO:0033554 269 0.021
programmed cell death GO:0012501 392 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
response to extracellular stimulus GO:0009991 380 0.021
brain development GO:0007420 247 0.021
regulation of cell morphogenesis GO:0022604 77 0.021
reproductive process GO:0022414 372 0.021
protein complex subunit organization GO:0071822 302 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
cellular nitrogen compound catabolic process GO:0044270 163 0.020
cellular ketone metabolic process GO:0042180 51 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
head development GO:0060322 247 0.020
amine metabolic process GO:0009308 38 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
regulation of cell proliferation GO:0042127 359 0.019
chemical homeostasis GO:0048878 292 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
immune system process GO:0002376 204 0.019
intracellular transport GO:0046907 185 0.019
Human
cellular amine metabolic process GO:0044106 38 0.019
positive regulation of nervous system development GO:0051962 178 0.019
cellular metal ion homeostasis GO:0006875 172 0.019
response to growth factor GO:0070848 189 0.019
regulation of anatomical structure size GO:0090066 135 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
cell morphogenesis GO:0000902 142 0.018
aromatic compound catabolic process GO:0019439 168 0.018
cellular chemical homeostasis GO:0055082 247 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
regulation of protein metabolic process GO:0051246 289 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
eye morphogenesis GO:0048592 4 0.018
aging GO:0007568 241 0.018
neurological system process GO:0050877 219 0.018
secretion by cell GO:0032940 248 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
positive regulation of neurogenesis GO:0050769 165 0.018
neuron projection morphogenesis GO:0048812 122 0.018
regulation of catalytic activity GO:0050790 304 0.018
heterocycle catabolic process GO:0046700 167 0.018
cation transport GO:0006812 382 0.017
secretion GO:0046903 307 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
negative regulation of cell communication GO:0010648 158 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
response to inorganic substance GO:0010035 377 0.017
regulation of signal transduction GO:0009966 318 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
regulation of cell development GO:0060284 263 0.017
single organism intracellular transport GO:1902582 166 0.017
Human
nucleobase containing compound catabolic process GO:0034655 152 0.017
reproduction GO:0000003 245 0.017
embryonic appendage morphogenesis GO:0035113 4 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
vesicle mediated transport GO:0016192 181 0.017
purine containing compound metabolic process GO:0072521 253 0.017
neuron projection development GO:0031175 273 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
negative regulation of gene expression GO:0010629 199 0.016
regulation of phosphorylation GO:0042325 248 0.016
transmembrane transport GO:0055085 412 0.016
cellular homeostasis GO:0019725 252 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
regulation of cell projection organization GO:0031344 175 0.016
regulation of apoptotic process GO:0042981 335 0.016
protein localization GO:0008104 191 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
positive regulation of developmental process GO:0051094 283 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
positive regulation of cell development GO:0010720 176 0.016
cellular response to growth factor stimulus GO:0071363 162 0.015
localization of cell GO:0051674 202 0.015
synaptic transmission GO:0007268 235 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
reproductive structure development GO:0048608 128 0.015
chromosome segregation GO:0007059 2 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
cellular protein localization GO:0034613 122 0.015
ossification GO:0001503 70 0.015
regulation of protein phosphorylation GO:0001932 183 0.014
cell projection morphogenesis GO:0048858 123 0.014
nucleoside metabolic process GO:0009116 179 0.014
axis specification GO:0009798 4 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
positive regulation of molecular function GO:0044093 230 0.014
double strand break repair GO:0006302 1 0.014
growth GO:0040007 165 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
axon development GO:0061564 96 0.014
response to oxygen levels GO:0070482 265 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
regulation of protein modification process GO:0031399 194 0.014
behavior GO:0007610 205 0.014
nucleotide catabolic process GO:0009166 139 0.013
response to peptide hormone GO:0043434 278 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
protein oligomerization GO:0051259 191 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
reproductive system development GO:0061458 128 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
negative regulation of developmental process GO:0051093 125 0.013
regulation of membrane potential GO:0042391 110 0.013
regulation of secretion by cell GO:1903530 208 0.013
regulation of neuron projection development GO:0010975 161 0.013
neuronal action potential GO:0019228 35 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
cation homeostasis GO:0055080 195 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
cell motility GO:0048870 202 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
anion transport GO:0006820 178 0.013
ras protein signal transduction GO:0007265 29 0.012
negative regulation of transport GO:0051051 136 0.012
regulation of axonogenesis GO:0050770 37 0.012
multicellular organism reproduction GO:0032504 233 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
negative regulation of nervous system development GO:0051961 79 0.012
regulation of cell growth GO:0001558 85 0.012
ion transmembrane transport GO:0034220 365 0.012
cell migration GO:0016477 197 0.012
regulation of catabolic process GO:0009894 113 0.012
heart morphogenesis GO:0003007 3 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
cation transmembrane transport GO:0098655 263 0.012
sex differentiation GO:0007548 113 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
lipid storage GO:0019915 1 0.012
positive regulation of signaling GO:0023056 270 0.012
hematopoietic or lymphoid organ development GO:0048534 36 0.012
embryonic skeletal system development GO:0048706 3 0.012
response to acid chemical GO:0001101 222 0.012
regulation of secretion GO:0051046 224 0.012
gastrulation GO:0007369 2 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of transmembrane transport GO:0034762 122 0.012
sexual reproduction GO:0019953 148 0.012
calcium ion homeostasis GO:0055074 162 0.012
response to wounding GO:0009611 254 0.012
dna metabolic process GO:0006259 96 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
negative regulation of cell death GO:0060548 229 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
response to cytokine GO:0034097 215 0.011
response to hypoxia GO:0001666 231 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
response to insulin GO:0032868 133 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
cardiovascular system development GO:0072358 134 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
regulation of locomotion GO:0040012 148 0.011
purine containing compound catabolic process GO:0072523 138 0.011
single organism organelle organization GO:1902589 180 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
regulation of growth GO:0040008 105 0.011
multicellular organism growth GO:0035264 1 0.011
negative regulation of innate immune response GO:0045824 4 0.011
cell growth GO:0016049 104 0.011
multi organism reproductive process GO:0044703 262 0.011
tissue development GO:0009888 252 0.011
anterior posterior pattern specification GO:0009952 1 0.011
cellular cation homeostasis GO:0030003 180 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
response to decreased oxygen levels GO:0036293 237 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
response to metal ion GO:0010038 253 0.011
response to carbohydrate GO:0009743 183 0.011
cytoplasmic transport GO:0016482 115 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
single organism biosynthetic process GO:0044711 342 0.011
development of primary sexual characteristics GO:0045137 107 0.011
regulation of programmed cell death GO:0043067 341 0.011
regulation of response to external stimulus GO:0032101 106 0.011
ion homeostasis GO:0050801 212 0.011
cellular response to insulin stimulus GO:0032869 81 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
regulation of cell motility GO:2000145 131 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
response to glucose GO:0009749 136 0.010
cellular macromolecule localization GO:0070727 122 0.010
camera type eye morphogenesis GO:0048593 2 0.010
negative regulation of signaling GO:0023057 157 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
endoplasmic reticulum organization GO:0007029 1 0.010
response to other organism GO:0051707 220 0.010

Plekha8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.017
connective tissue disease DOID:65 0 0.013
central nervous system disease DOID:331 0 0.013