Rattus norvegicus

83 known processes

Slc25a4

solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4

(Aliases: Ant1)

Slc25a4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cofactor metabolic process GO:0051186 95 0.712
Yeast
purine nucleotide biosynthetic process GO:0006164 83 0.649
Fly
nucleotide metabolic process GO:0009117 279 0.642
Fly
nucleoside monophosphate metabolic process GO:0009123 93 0.614
Fly
carboxylic acid metabolic process GO:0019752 289 0.585
organic acid metabolic process GO:0006082 292 0.452
apoptotic mitochondrial changes GO:0008637 10 0.418
Mouse
oxoacid metabolic process GO:0043436 290 0.399
purine nucleoside monophosphate metabolic process GO:0009126 84 0.393
Fly
purine ribonucleoside biosynthetic process GO:0046129 21 0.369
Fly
ribonucleoside monophosphate metabolic process GO:0009161 88 0.340
Fly
nucleoside phosphate metabolic process GO:0006753 283 0.338
Fly
nucleobase containing small molecule metabolic process GO:0055086 316 0.333
Fly
purine nucleoside metabolic process GO:0042278 169 0.319
Fly
generation of precursor metabolites and energy GO:0006091 62 0.314
Yeast
carbohydrate derivative metabolic process GO:1901135 346 0.284
Fly
cellular component biogenesis GO:0044085 368 0.279
Fly
regulation of apoptotic process GO:0042981 335 0.267
nucleoside triphosphate metabolic process GO:0009141 144 0.261
Fly
apoptotic process GO:0006915 381 0.259
Yeast Mouse
purine containing compound metabolic process GO:0072521 253 0.208
Fly
glycosyl compound metabolic process GO:1901657 182 0.202
Fly
cell cell signaling GO:0007267 335 0.200
purine ribonucleoside metabolic process GO:0046128 168 0.195
Fly
positive regulation of atp biosynthetic process GO:2001171 2 0.195
Fly
oxidation reduction process GO:0055114 304 0.181
Yeast
response to oxidative stress GO:0006979 186 0.170
Fly
dicarboxylic acid metabolic process GO:0043648 42 0.168
regulation of programmed cell death GO:0043067 341 0.166
Human
ribonucleoside metabolic process GO:0009119 174 0.164
Fly
negative regulation of apoptotic process GO:0043066 181 0.163
cation transmembrane transport GO:0098655 263 0.155
macromolecular complex assembly GO:0065003 273 0.154
anion transport GO:0006820 178 0.153
monovalent inorganic cation transport GO:0015672 172 0.152
ion homeostasis GO:0050801 212 0.134
Fly
macromolecular complex subunit organization GO:0043933 339 0.132
response to hydrogen peroxide GO:0042542 89 0.132
response to decreased oxygen levels GO:0036293 237 0.131
cellular response to oxygen containing compound GO:1901701 386 0.123
neuron apoptotic process GO:0051402 88 0.117
regulation of system process GO:0044057 208 0.113
adenine nucleotide transport GO:0051503 2 0.111
catabolic process GO:0009056 351 0.106
cold acclimation GO:0009631 1 0.099
neurotransmitter uptake GO:0001504 3 0.098
cellular component assembly GO:0022607 360 0.098
Fly
circulatory system development GO:0072359 134 0.097
atp metabolic process GO:0046034 72 0.096
Fly
response to temperature stimulus GO:0009266 94 0.089
single organism biosynthetic process GO:0044711 342 0.088
Yeast Fly
purine nucleoside biosynthetic process GO:0042451 21 0.086
Fly
metal ion transport GO:0030001 289 0.085
programmed cell death GO:0012501 392 0.083
Human Yeast Mouse
anatomical structure morphogenesis GO:0009653 298 0.082
nad metabolic process GO:0019674 15 0.080
organophosphate biosynthetic process GO:0090407 143 0.080
Fly
organic substance catabolic process GO:1901575 316 0.079
mitotic dna damage checkpoint GO:0044773 1 0.079
positive regulation of ion transport GO:0043270 94 0.077
cation transport GO:0006812 382 0.077
protein complex subunit organization GO:0071822 302 0.076
nitrogen compound transport GO:0071705 229 0.073
metal ion homeostasis GO:0055065 186 0.073
Fly
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.072
Fly
cellular response to stress GO:0033554 269 0.072
Fly
single organism behavior GO:0044708 130 0.071
Fly
energy derivation by oxidation of organic compounds GO:0015980 46 0.070
Yeast
organelle organization GO:0006996 266 0.068
Mouse
cellular homeostasis GO:0019725 252 0.068
Fly
protein complex assembly GO:0006461 263 0.066
response to reactive oxygen species GO:0000302 120 0.066
response to acid chemical GO:0001101 222 0.065
mitochondrial calcium ion transport GO:0006851 2 0.064
cell redox homeostasis GO:0045454 1 0.064
aspartate family amino acid biosynthetic process GO:0009067 4 0.062
organ regeneration GO:0031100 101 0.062
response to extracellular stimulus GO:0009991 380 0.061
response to carbohydrate GO:0009743 183 0.061
liver development GO:0001889 90 0.059
behavior GO:0007610 205 0.059
Fly
ribose phosphate metabolic process GO:0019693 235 0.059
Fly
response to hypoxia GO:0001666 231 0.059
cell cycle checkpoint GO:0000075 2 0.059
nadh metabolic process GO:0006734 10 0.058
vesicle mediated transport GO:0016192 181 0.058
Fly
negative regulation of response to stimulus GO:0048585 155 0.058
multicellular organismal reproductive process GO:0048609 233 0.057
nucleotide biosynthetic process GO:0009165 98 0.057
Fly
carbohydrate derivative biosynthetic process GO:1901137 124 0.056
Fly
ribonucleotide biosynthetic process GO:0009260 85 0.055
Fly
cellular chemical homeostasis GO:0055082 247 0.055
Fly
response to oxygen levels GO:0070482 265 0.054
cellular response to organonitrogen compound GO:0071417 197 0.053
regulation of cellular localization GO:0060341 263 0.053
protein complex biogenesis GO:0070271 263 0.052
organonitrogen compound catabolic process GO:1901565 179 0.052
carbohydrate catabolic process GO:0016052 40 0.052
ion transmembrane transport GO:0034220 365 0.051
purine nucleoside triphosphate biosynthetic process GO:0009145 6 0.051
Fly
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.051
nucleoside metabolic process GO:0009116 179 0.050
Fly
response to organophosphorus GO:0046683 102 0.049
response to nutrient levels GO:0031667 370 0.049
response to molecule of bacterial origin GO:0002237 194 0.049
nucleoside triphosphate biosynthetic process GO:0009142 8 0.049
Fly
ribonucleotide metabolic process GO:0009259 231 0.049
Fly
purine nucleotide metabolic process GO:0006163 229 0.048
Fly
regulation of catalytic activity GO:0050790 304 0.048
porphyrin containing compound metabolic process GO:0006778 8 0.046
Yeast
protein oligomerization GO:0051259 191 0.046
heart process GO:0003015 57 0.046
cation homeostasis GO:0055080 195 0.045
Fly
blood circulation GO:0008015 183 0.045
positive regulation of cell death GO:0010942 184 0.045
response to hexose GO:0009746 144 0.044
response to monosaccharide GO:0034284 159 0.044
reproduction GO:0000003 245 0.044
porphyrin containing compound biosynthetic process GO:0006779 6 0.043
Yeast
regulation of nucleotide biosynthetic process GO:0030808 47 0.043
Fly
monocarboxylic acid metabolic process GO:0032787 152 0.042
single organism carbohydrate catabolic process GO:0044724 40 0.042
transmembrane transport GO:0055085 412 0.042
regulation of ion transport GO:0043269 245 0.041
response to other organism GO:0051707 220 0.041
homeostatic process GO:0042592 331 0.041
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.041
Fly
response to peptide hormone GO:0043434 278 0.040
intracellular transport GO:0046907 185 0.040
Yeast Fly
single organism carbohydrate metabolic process GO:0044723 118 0.040
positive regulation of cell proliferation GO:0008284 249 0.040
negative regulation of cell communication GO:0010648 158 0.040
reproductive process GO:0022414 372 0.040
regulation of purine nucleotide metabolic process GO:1900542 115 0.039
Fly
negative regulation of cellular component organization GO:0051129 83 0.039
intracellular signal transduction GO:0035556 314 0.039
negative regulation of transport GO:0051051 136 0.039
regulation of phosphate metabolic process GO:0019220 349 0.039
Fly
single organism catabolic process GO:0044712 283 0.038
response to nutrient GO:0007584 248 0.038
purine nucleoside triphosphate metabolic process GO:0009144 141 0.037
Fly
malate metabolic process GO:0006108 5 0.037
brain development GO:0007420 247 0.037
cellular metal ion homeostasis GO:0006875 172 0.037
Fly
cellular response to endogenous stimulus GO:0071495 377 0.037
cell cell signaling involved in cell fate commitment GO:0045168 2 0.036
multi organism reproductive process GO:0044703 262 0.036
regulation of mitotic cell cycle phase transition GO:1901990 11 0.036
tetrapyrrole metabolic process GO:0033013 11 0.036
Yeast
ribonucleoside monophosphate biosynthetic process GO:0009156 24 0.035
Fly
developmental process involved in reproduction GO:0003006 159 0.035
membrane organization GO:0061024 94 0.035
regulation of membrane potential GO:0042391 110 0.034
Fly
nucleoside biosynthetic process GO:0009163 25 0.034
Fly
response to inorganic substance GO:0010035 377 0.034
positive regulation of phosphate metabolic process GO:0045937 262 0.034
Fly
cell type specific apoptotic process GO:0097285 134 0.033
purine ribonucleotide biosynthetic process GO:0009152 81 0.033
Fly
l glutamate import GO:0051938 2 0.032
cellular component movement GO:0006928 248 0.031
cellular response to insulin stimulus GO:0032869 81 0.030
cellular catabolic process GO:0044248 295 0.030
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.030
Fly
negative regulation of cell death GO:0060548 229 0.029
Human
cellular response to nitrogen compound GO:1901699 210 0.029
sexual reproduction GO:0019953 148 0.029
single organism reproductive process GO:0044702 297 0.029
cofactor biosynthetic process GO:0051188 28 0.029
Yeast
coenzyme metabolic process GO:0006732 86 0.028
regulation of apoptotic signaling pathway GO:2001233 13 0.028
ribonucleoside biosynthetic process GO:0042455 25 0.028
Fly
response to glucose GO:0009749 136 0.028
regulation of hydrolase activity GO:0051336 143 0.028
single organism membrane organization GO:0044802 74 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
cellular cation homeostasis GO:0030003 180 0.027
Fly
cellular response to hormone stimulus GO:0032870 247 0.027
inorganic ion transmembrane transport GO:0098660 229 0.027
purine ribonucleotide metabolic process GO:0009150 227 0.027
Fly
muscle contraction GO:0006936 88 0.027
response to radiation GO:0009314 137 0.027
regulation of cellular component organization GO:0051128 368 0.027
divalent metal ion transport GO:0070838 132 0.027
glycosyl compound biosynthetic process GO:1901659 25 0.027
Fly
ribose phosphate biosynthetic process GO:0046390 87 0.026
Fly
nicotinamide nucleotide metabolic process GO:0046496 28 0.026
amino acid transport GO:0006865 70 0.026
response to starvation GO:0042594 59 0.026
response to purine containing compound GO:0014074 126 0.025
regulation of signal transduction GO:0009966 318 0.025
multicellular organism reproduction GO:0032504 233 0.025
regeneration GO:0031099 163 0.025
carboxylic acid transport GO:0046942 115 0.025
calcium ion transport GO:0006816 131 0.025
growth GO:0040007 165 0.024
Fly
negative regulation of multicellular organismal process GO:0051241 203 0.024
negative regulation of metabolic process GO:0009892 331 0.024
purine nucleoside diphosphate biosynthetic process GO:0009136 9 0.024
regulation of secretion GO:0051046 224 0.024
electron transport chain GO:0022900 5 0.024
synaptic growth at neuromuscular junction GO:0051124 1 0.024
Fly
cellular nitrogen compound catabolic process GO:0044270 163 0.024
muscle system process GO:0003012 115 0.024
neuron death GO:0070997 127 0.023
regulation of cell proliferation GO:0042127 359 0.023
cellular component morphogenesis GO:0032989 155 0.023
purine nucleotide transport GO:0015865 3 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
Human
ribonucleoside triphosphate metabolic process GO:0009199 141 0.023
Fly
regulation of growth GO:0040008 105 0.023
heme biosynthetic process GO:0006783 4 0.022
Yeast
organonitrogen compound biosynthetic process GO:1901566 167 0.022
Yeast Fly
positive regulation of programmed cell death GO:0043068 157 0.022
organic anion transport GO:0015711 132 0.022
nucleoside phosphate biosynthetic process GO:1901293 102 0.022
Fly
response to estrogen GO:0043627 232 0.022
inorganic cation transmembrane transport GO:0098662 202 0.022
neurotransmitter transport GO:0006836 42 0.022
cellular respiration GO:0045333 21 0.021
Yeast
regulation of neurotransmitter levels GO:0001505 42 0.021
response to corticosteroid GO:0031960 235 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.021
Fly
divalent inorganic cation transport GO:0072511 134 0.021
regulation of molecular function GO:0065009 398 0.021
response to ketone GO:1901654 182 0.021
protein homooligomerization GO:0051260 91 0.021
monosaccharide metabolic process GO:0005996 61 0.020
single organism intracellular transport GO:1902582 166 0.020
Yeast Fly
negative regulation of growth GO:0045926 37 0.020
cardiovascular system development GO:0072358 134 0.020
spermatogenesis GO:0007283 99 0.020
negative regulation of cell cycle phase transition GO:1901988 4 0.020
response to toxic substance GO:0009636 133 0.020
cellular response to peptide GO:1901653 133 0.019
central nervous system development GO:0007417 311 0.019
muscle structure development GO:0061061 87 0.019
dna integrity checkpoint GO:0031570 2 0.019
anion transmembrane transport GO:0098656 77 0.019
chemical homeostasis GO:0048878 292 0.019
Fly
negative regulation of signal transduction GO:0009968 83 0.018
oxidoreduction coenzyme metabolic process GO:0006733 31 0.018
response to insulin GO:0032868 133 0.018
negative regulation of molecular function GO:0044092 133 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
Fly
single organism organelle organization GO:1902589 180 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
tricarboxylic acid metabolic process GO:0072350 10 0.018
organic cyclic compound catabolic process GO:1901361 175 0.017
heart development GO:0007507 72 0.017
positive regulation of nucleotide metabolic process GO:0045981 91 0.017
Fly
regulation of protein modification process GO:0031399 194 0.017
pyruvate metabolic process GO:0006090 27 0.017
organophosphate catabolic process GO:0046434 148 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
Fly
rna metabolic process GO:0016070 406 0.017
nucleotide catabolic process GO:0009166 139 0.017
regulation of membrane permeability GO:0090559 5 0.017
protein tetramerization GO:0051262 38 0.017
organophosphate metabolic process GO:0019637 370 0.016
Fly
purine ribonucleoside monophosphate biosynthetic process GO:0009168 20 0.016
Fly
purine containing compound catabolic process GO:0072523 138 0.016
cellular modified amino acid metabolic process GO:0006575 61 0.016
organic hydroxy compound metabolic process GO:1901615 115 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
Fly
adult locomotory behavior GO:0008344 4 0.016
Fly
nucleoside transport GO:0015858 8 0.016
synaptic transmission GO:0007268 235 0.016
peptidyl amino acid modification GO:0018193 126 0.016
response to mechanical stimulus GO:0009612 134 0.016
Fly
response to fatty acid GO:0070542 65 0.016
aerobic respiration GO:0009060 13 0.016
Yeast
secretion by cell GO:0032940 248 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
alditol metabolic process GO:0019400 4 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
protein phosphorylation GO:0006468 345 0.015
gamete generation GO:0007276 124 0.015
reproductive structure development GO:0048608 128 0.015
g2 dna damage checkpoint GO:0031572 1 0.015
heart morphogenesis GO:0003007 3 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
regulation of atp metabolic process GO:1903578 9 0.015
Fly
regulation of intracellular signal transduction GO:1902531 218 0.015
atp catabolic process GO:0006200 54 0.015
response to electrical stimulus GO:0051602 56 0.015
regulation of neuron apoptotic process GO:0043523 83 0.015
cellular protein complex assembly GO:0043623 44 0.014
regulation of mitochondrion organization GO:0010821 7 0.014
mitochondrion organization GO:0007005 35 0.014
Mouse
dicarboxylic acid transport GO:0006835 34 0.014
head development GO:0060322 247 0.014
dna damage checkpoint GO:0000077 2 0.014
regulation of muscle system process GO:0090257 79 0.014
sulfur compound metabolic process GO:0006790 70 0.014
immune system process GO:0002376 204 0.014
cellular response to lipid GO:0071396 201 0.014
response to bacterium GO:0009617 200 0.014
cellular response to oxidative stress GO:0034599 76 0.014
Fly
appendage morphogenesis GO:0035107 4 0.014
cellular amine metabolic process GO:0044106 38 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
Fly
citrate metabolic process GO:0006101 3 0.013
apoptotic signaling pathway GO:0097190 27 0.013
protein polymerization GO:0051258 22 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
response to ethanol GO:0045471 162 0.013
protein homotetramerization GO:0051289 25 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
Fly
negative regulation of catalytic activity GO:0043086 103 0.013
response to peptide GO:1901652 292 0.013
rhythmic process GO:0048511 156 0.013
glycosyl compound catabolic process GO:1901658 126 0.012
defense response GO:0006952 194 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
heart contraction GO:0060047 57 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
regulation of cell differentiation GO:0045595 320 0.012
positive regulation of protein modification process GO:0031401 142 0.012
blood vessel morphogenesis GO:0048514 58 0.012
regulation of hormone levels GO:0010817 187 0.012
cell cycle GO:0007049 101 0.012
proteolysis GO:0006508 175 0.012
response to estradiol GO:0032355 164 0.012
regulation of secretion by cell GO:1903530 208 0.012
regulation of cell cycle GO:0051726 73 0.012
regulation of anatomical structure size GO:0090066 135 0.012
neuron differentiation GO:0030182 368 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
aging GO:0007568 241 0.011
Fly
positive regulation of transport GO:0051050 245 0.011
myoblast fusion GO:0007520 2 0.011
regulation of tube size GO:0035150 89 0.011
organophosphate ester transport GO:0015748 10 0.011
male gamete generation GO:0048232 99 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
negative regulation of neuron death GO:1901215 69 0.011
positive regulation of cell development GO:0010720 176 0.011
regulation of multicellular organismal development GO:2000026 376 0.011
circulatory system process GO:0003013 183 0.011
secretion GO:0046903 307 0.011
germ cell development GO:0007281 25 0.011
response to interleukin 1 GO:0070555 55 0.011
regulation of transcription dna templated GO:0006355 374 0.011
response to amino acid GO:0043200 75 0.011
negative regulation of protein metabolic process GO:0051248 114 0.010
l amino acid transport GO:0015807 21 0.010
response to metal ion GO:0010038 253 0.010
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.010
Fly
positive regulation of molecular function GO:0044093 230 0.010
regulation of mapk cascade GO:0043408 116 0.010
cell cycle phase transition GO:0044770 21 0.010
response to ammonium ion GO:0060359 71 0.010
sex differentiation GO:0007548 113 0.010
carboxylic acid biosynthetic process GO:0046394 83 0.010
purine ribonucleoside diphosphate biosynthetic process GO:0009180 9 0.010
regulation of blood pressure GO:0008217 83 0.010
response to antibiotic GO:0046677 39 0.010

Slc25a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
nervous system disease DOID:863 0 0.054
sensory system disease DOID:0050155 0 0.034
eye and adnexa disease DOID:1492 0 0.034
musculoskeletal system disease DOID:17 0 0.025
eye disease DOID:5614 0 0.025
myopathy DOID:423 0 0.022
muscular disease DOID:0080000 0 0.022
heart disease DOID:114 0 0.022
cardiomyopathy DOID:0050700 0 0.022
dilated cardiomyopathy DOID:12930 0 0.022
intrinsic cardiomyopathy DOID:0060036 0 0.022
cardiovascular system disease DOID:1287 0 0.022
muscle tissue disease DOID:66 0 0.022
gastrointestinal system cancer DOID:3119 0 0.017
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
disease of metabolism DOID:0014667 0 0.012
central nervous system disease DOID:331 0 0.011