Rattus norvegicus

14 known processes

Chrna5

cholinergic receptor, nicotinic, alpha 5

Chrna5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular chemical homeostasis GO:0055082 247 0.290
cellular response to oxygen containing compound GO:1901701 386 0.246
regulation of ion transport GO:0043269 245 0.239
Rat
homeostatic process GO:0042592 331 0.233
cellular response to endogenous stimulus GO:0071495 377 0.215
sensory perception GO:0007600 101 0.207
Rat
cellular response to organic cyclic compound GO:0071407 202 0.197
cellular homeostasis GO:0019725 252 0.194
cell cell signaling GO:0007267 335 0.183
Human Rat Fly
ion transmembrane transport GO:0034220 365 0.175
neurological system process GO:0050877 219 0.166
Rat
regulation of cellular component organization GO:0051128 368 0.162
rna metabolic process GO:0016070 406 0.120
neuron differentiation GO:0030182 368 0.113
inorganic ion transmembrane transport GO:0098660 229 0.112
Rat
regulation of signal transduction GO:0009966 318 0.104
organelle organization GO:0006996 266 0.103
chemical homeostasis GO:0048878 292 0.101
locomotion GO:0040011 237 0.101
cellular response to nitrogen compound GO:1901699 210 0.100
cellular component assembly GO:0022607 360 0.100
Rat
nucleic acid templated transcription GO:0097659 379 0.097
single organism organelle organization GO:1902589 180 0.094
ion homeostasis GO:0050801 212 0.091
positive regulation of cellular component organization GO:0051130 200 0.091
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.088
regulation of multicellular organismal development GO:2000026 376 0.085
cytoskeleton organization GO:0007010 111 0.084
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.083
response to estrogen GO:0043627 232 0.083
cellular component biogenesis GO:0044085 368 0.081
Rat
response to inorganic substance GO:0010035 377 0.080
Rat
secretion GO:0046903 307 0.075
Rat
programmed cell death GO:0012501 392 0.074
cellular cation homeostasis GO:0030003 180 0.074
transcription from rna polymerase ii promoter GO:0006366 252 0.072
positive regulation of rna biosynthetic process GO:1902680 197 0.071
regulation of rna metabolic process GO:0051252 391 0.070
transcription dna templated GO:0006351 377 0.070
single organism reproductive process GO:0044702 297 0.069
regulation of programmed cell death GO:0043067 341 0.069
positive regulation of developmental process GO:0051094 283 0.069
synaptic transmission GO:0007268 235 0.067
Human Rat Fly
circulatory system process GO:0003013 183 0.065
blood circulation GO:0008015 183 0.063
tissue development GO:0009888 252 0.062
neuronal action potential GO:0019228 35 0.061
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.061
cellular metal ion homeostasis GO:0006875 172 0.060
cell projection organization GO:0030030 302 0.059
negative regulation of apoptotic process GO:0043066 181 0.059
positive regulation of gene expression GO:0010628 244 0.059
cation transport GO:0006812 382 0.058
cellular component morphogenesis GO:0032989 155 0.058
regulation of membrane potential GO:0042391 110 0.058
multicellular organismal signaling GO:0035637 44 0.057
regulation of cellular localization GO:0060341 263 0.057
Rat
neuron projection morphogenesis GO:0048812 122 0.057
regulation of establishment of planar polarity GO:0090175 2 0.056
transmission of nerve impulse GO:0019226 42 0.056
muscle contraction GO:0006936 88 0.056
Rat
regulation of cell differentiation GO:0045595 320 0.056
negative regulation of cellular metabolic process GO:0031324 281 0.055
multi organism reproductive process GO:0044703 262 0.055
reproduction GO:0000003 245 0.055
secretion by cell GO:0032940 248 0.054
Rat
muscle system process GO:0003012 115 0.054
Rat
regulation of system process GO:0044057 208 0.053
neuron development GO:0048666 286 0.053
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.053
apoptotic process GO:0006915 381 0.052
positive regulation of multicellular organismal process GO:0051240 387 0.051
brain development GO:0007420 247 0.051
regulation of nucleic acid templated transcription GO:1903506 380 0.051
positive regulation of nucleic acid templated transcription GO:1903508 197 0.050
cell motility GO:0048870 202 0.050
regulation of secretion GO:0051046 224 0.050
Rat
regulation of anatomical structure size GO:0090066 135 0.048
vascular process in circulatory system GO:0003018 96 0.048
cell projection morphogenesis GO:0048858 123 0.048
regulation of rna biosynthetic process GO:2001141 381 0.048
central nervous system development GO:0007417 311 0.048
multicellular organismal reproductive process GO:0048609 233 0.047
cellular response to lipid GO:0071396 201 0.047
neuron projection development GO:0031175 273 0.047
negative regulation of cell death GO:0060548 229 0.046
response to metal ion GO:0010038 253 0.045
protein complex assembly GO:0006461 263 0.045
Rat
regulation of heart contraction GO:0008016 48 0.045
regulation of phosphorus metabolic process GO:0051174 349 0.044
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.044
cellular ion homeostasis GO:0006873 184 0.044
regulation of homeostatic process GO:0032844 101 0.043
positive regulation of programmed cell death GO:0043068 157 0.043
regulation of secretion by cell GO:1903530 208 0.043
Rat
negative regulation of signaling GO:0023057 157 0.042
anion transport GO:0006820 178 0.042
immune response GO:0006955 104 0.041
calcium mediated signaling GO:0019722 23 0.041
head development GO:0060322 247 0.041
lipid metabolic process GO:0006629 283 0.041
negative regulation of programmed cell death GO:0043069 183 0.041
positive regulation of cell proliferation GO:0008284 249 0.041
response to carbohydrate GO:0009743 183 0.040
actin filament based process GO:0030029 86 0.040
regulation of blood vessel size GO:0050880 89 0.040
positive regulation of cellular biosynthetic process GO:0031328 295 0.040
response to wounding GO:0009611 254 0.039
positive regulation of signal transduction GO:0009967 175 0.039
regulation of neuron differentiation GO:0045664 208 0.039
regulation of cell proliferation GO:0042127 359 0.038
regulation of transcription dna templated GO:0006355 374 0.038
cellular divalent inorganic cation homeostasis GO:0072503 162 0.037
regulation of cell projection organization GO:0031344 175 0.037
dendrite development GO:0016358 72 0.035
multicellular organism growth GO:0035264 1 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
cytosolic calcium ion homeostasis GO:0051480 140 0.035
sensory perception of pain GO:0019233 73 0.035
vasoconstriction GO:0042310 54 0.035
regulation of muscle contraction GO:0006937 53 0.035
macromolecular complex subunit organization GO:0043933 339 0.034
Rat
regulation of blood circulation GO:1903522 110 0.034
regulation of cellular component biogenesis GO:0044087 86 0.034
response to glucocorticoid GO:0051384 223 0.034
reproductive process GO:0022414 372 0.034
cellular calcium ion homeostasis GO:0006874 160 0.034
positive regulation of cell death GO:0010942 184 0.033
regulation of cell development GO:0060284 263 0.033
positive regulation of response to stimulus GO:0048584 285 0.033
regulation of blood pressure GO:0008217 83 0.033
divalent inorganic cation homeostasis GO:0072507 165 0.033
positive regulation of intracellular signal transduction GO:1902533 138 0.033
regulation of apoptotic process GO:0042981 335 0.033
positive regulation of ion transport GO:0043270 94 0.032
Rat
purine containing compound metabolic process GO:0072521 253 0.032
sexual reproduction GO:0019953 148 0.032
regulation of neuron projection development GO:0010975 161 0.032
regulation of neuron apoptotic process GO:0043523 83 0.032
cellular response to peptide GO:1901653 133 0.031
negative regulation of biosynthetic process GO:0009890 168 0.031
organic hydroxy compound metabolic process GO:1901615 115 0.031
g protein coupled receptor signaling pathway GO:0007186 242 0.031
Rat
regulation of phosphorylation GO:0042325 248 0.031
response to extracellular stimulus GO:0009991 380 0.031
mapk cascade GO:0000165 140 0.030
aging GO:0007568 241 0.030
positive regulation of transcription dna templated GO:0045893 197 0.030
carboxylic acid transport GO:0046942 115 0.030
forebrain development GO:0030900 98 0.030
positive regulation of catalytic activity GO:0043085 184 0.030
response to nutrient GO:0007584 248 0.030
positive regulation of signaling GO:0023056 270 0.030
alcohol metabolic process GO:0006066 77 0.030
negative regulation of transcription dna templated GO:0045892 116 0.029
metal ion homeostasis GO:0055065 186 0.029
response to glucose GO:0009749 136 0.029
organic anion transport GO:0015711 132 0.029
negative regulation of cell communication GO:0010648 158 0.029
cellular amine metabolic process GO:0044106 38 0.029
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.028
amine metabolic process GO:0009308 38 0.028
intracellular signal transduction GO:0035556 314 0.028
regulation of nervous system development GO:0051960 264 0.028
protein phosphorylation GO:0006468 345 0.028
response to ketone GO:1901654 182 0.028
negative regulation of metabolic process GO:0009892 331 0.028
regulation of muscle system process GO:0090257 79 0.028
cellular response to glucocorticoid stimulus GO:0071385 68 0.027
positive regulation of apoptotic process GO:0043065 154 0.027
cellular response to corticosteroid stimulus GO:0071384 69 0.027
response to monosaccharide GO:0034284 159 0.027
wound healing GO:0042060 122 0.027
negative regulation of response to stimulus GO:0048585 155 0.027
cellular response to hexose stimulus GO:0071331 65 0.027
anatomical structure morphogenesis GO:0009653 298 0.026
glucose homeostasis GO:0042593 75 0.026
protein complex biogenesis GO:0070271 263 0.026
Rat
positive regulation of neurogenesis GO:0050769 165 0.026
regulation of neurogenesis GO:0050767 247 0.026
neuron neuron synaptic transmission GO:0007270 60 0.026
regulation of neurological system process GO:0031644 43 0.026
cation transmembrane transport GO:0098655 263 0.026
anion transmembrane transport GO:0098656 77 0.026
regulation of sensory perception of pain GO:0051930 29 0.026
rhythmic process GO:0048511 156 0.026
response to hexose GO:0009746 144 0.026
rna biosynthetic process GO:0032774 380 0.026
calcium ion homeostasis GO:0055074 162 0.025
regulation of ion transmembrane transport GO:0034765 121 0.025
Rat
regulation of synaptic transmission GO:0050804 141 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
action potential GO:0001508 54 0.025
multicellular organism reproduction GO:0032504 233 0.025
response to growth factor GO:0070848 189 0.025
Rat
adult locomotory behavior GO:0008344 4 0.025
cellular response to organonitrogen compound GO:0071417 197 0.024
metal ion transport GO:0030001 289 0.024
Rat
organic substance catabolic process GO:1901575 316 0.024
cellular response to peptide hormone stimulus GO:0071375 120 0.024
nitrogen compound transport GO:0071705 229 0.024
Rat
positive regulation of neuron differentiation GO:0045666 126 0.024
protein homooligomerization GO:0051260 91 0.024
signal transduction by phosphorylation GO:0023014 144 0.024
regulation of molecular function GO:0065009 398 0.024
neuron apoptotic process GO:0051402 88 0.024
negative regulation of cell proliferation GO:0008285 119 0.023
regulation of response to external stimulus GO:0032101 106 0.023
response to ammonium ion GO:0060359 71 0.023
Rat
defense response GO:0006952 194 0.023
cell part morphogenesis GO:0032990 123 0.023
immune system process GO:0002376 204 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.022
response to alkaloid GO:0043279 132 0.022
Human Mouse Rat
nucleoside phosphate metabolic process GO:0006753 283 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
monovalent inorganic cation transport GO:0015672 172 0.022
Rat
axon ensheathment GO:0008366 40 0.022
macromolecular complex assembly GO:0065003 273 0.022
Rat
synaptic transmission glycinergic GO:0060012 2 0.022
cellular ketone metabolic process GO:0042180 51 0.022
positive regulation of nervous system development GO:0051962 178 0.021
gastrulation GO:0007369 2 0.021
response to hypoxia GO:0001666 231 0.021
axis specification GO:0009798 4 0.021
regulation of transmembrane transport GO:0034762 122 0.021
Rat
signal release GO:0023061 145 0.021
heart contraction GO:0060047 57 0.021
cation homeostasis GO:0055080 195 0.021
epithelium development GO:0060429 96 0.021
positive regulation of secretion GO:0051047 140 0.021
Rat
peptide transport GO:0015833 97 0.021
heart process GO:0003015 57 0.020
monocarboxylic acid transport GO:0015718 52 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
heart morphogenesis GO:0003007 3 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
neuron death GO:0070997 127 0.019
regulation of cellular component movement GO:0051270 150 0.019
positive regulation of cellular component biogenesis GO:0044089 55 0.019
carbohydrate homeostasis GO:0033500 75 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
positive regulation of molecular function GO:0044093 230 0.019
second messenger mediated signaling GO:0019932 51 0.019
response to ethanol GO:0045471 162 0.019
Rat
biological adhesion GO:0022610 110 0.019
response to acid chemical GO:0001101 222 0.019
organonitrogen compound catabolic process GO:1901565 179 0.018
negative regulation of gene expression GO:0010629 199 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
response to nutrient levels GO:0031667 370 0.018
response to toxic substance GO:0009636 133 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.018
regulation of protein metabolic process GO:0051246 289 0.018
response to amphetamine GO:0001975 25 0.018
regulation of odontogenesis GO:0042481 4 0.018
cellular response to cytokine stimulus GO:0071345 127 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
regulation of neuron death GO:1901214 115 0.017
establishment of protein localization GO:0045184 141 0.017
response to radiation GO:0009314 137 0.017
cellular response to carbohydrate stimulus GO:0071322 72 0.017
potassium ion transport GO:0006813 97 0.017
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.017
cellular response to alcohol GO:0097306 87 0.017
positive regulation of cell development GO:0010720 176 0.017
response to histamine GO:0034776 3 0.017
regulation of response to stress GO:0080134 126 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
embryonic pattern specification GO:0009880 1 0.017
inorganic cation transmembrane transport GO:0098662 202 0.017
Rat
organophosphate metabolic process GO:0019637 370 0.017
odontogenesis GO:0042476 32 0.016
telencephalon development GO:0021537 62 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
response to peptide GO:1901652 292 0.016
regulation of metal ion transport GO:0010959 118 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
negative regulation of signal transduction GO:0009968 83 0.016
peristalsis GO:0030432 2 0.016
cell migration GO:0016477 197 0.016
nucleotide metabolic process GO:0009117 279 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
bmp signaling pathway GO:0030509 4 0.016
choline transport GO:0015871 4 0.016
gamete generation GO:0007276 124 0.016
response to light stimulus GO:0009416 52 0.015
positive regulation of mapk cascade GO:0043410 92 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
regulation of vesicle mediated transport GO:0060627 81 0.015
cellular component movement GO:0006928 248 0.015
amino acid transport GO:0006865 70 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
response to estradiol GO:0032355 164 0.015
cellular response to glucose stimulus GO:0071333 65 0.015
regulation of protein modification process GO:0031399 194 0.015
oxoacid metabolic process GO:0043436 290 0.015
regulation of hormone levels GO:0010817 187 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.014
regulation of neurotransmitter levels GO:0001505 42 0.014
regulation of calcium ion transport GO:0051924 77 0.014
cellular protein complex assembly GO:0043623 44 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
multi multicellular organism process GO:0044706 138 0.014
male gamete generation GO:0048232 99 0.014
hormone secretion GO:0046879 115 0.014
regulation of catalytic activity GO:0050790 304 0.014
actin mediated cell contraction GO:0070252 12 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
circadian rhythm GO:0007623 88 0.014
regulation of hormone secretion GO:0046883 106 0.014
positive regulation of secretion by cell GO:1903532 128 0.013
Rat
regulation of immune response GO:0050776 55 0.013
erk1 and erk2 cascade GO:0070371 48 0.013
positive regulation of transport GO:0051050 245 0.013
Rat
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.013
activation of protein kinase activity GO:0032147 47 0.013
negative regulation of neuron death GO:1901215 69 0.013
potassium ion transmembrane transport GO:0071805 71 0.013
Rat
cell type specific apoptotic process GO:0097285 134 0.013
regulation of smooth muscle contraction GO:0006940 29 0.013
nucleoside catabolic process GO:0009164 126 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
single organism biosynthetic process GO:0044711 342 0.013
cellular response to external stimulus GO:0071496 118 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
heart development GO:0007507 72 0.013
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
sequestering of metal ion GO:0051238 9 0.013
catabolic process GO:0009056 351 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
Rat
glycosyl compound catabolic process GO:1901658 126 0.013
response to oxygen levels GO:0070482 265 0.013
heterocycle catabolic process GO:0046700 167 0.013
positive regulation of cell migration GO:0030335 96 0.012
regulation of peptide transport GO:0090087 87 0.012
response to peptide hormone GO:0043434 278 0.012
axon development GO:0061564 96 0.012
cellular glucose homeostasis GO:0001678 66 0.012
response to amine GO:0014075 46 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
negative regulation of neuron apoptotic process GO:0043524 45 0.012
response to calcium ion GO:0051592 59 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
organic hydroxy compound transport GO:0015850 77 0.012
Rat
neurotransmitter transport GO:0006836 42 0.012
macromolecule localization GO:0033036 252 0.012
hormone transport GO:0009914 121 0.012
regulation of sensory perception GO:0051931 29 0.012
nucleoside metabolic process GO:0009116 179 0.012
membrane depolarization GO:0051899 32 0.012
small molecule biosynthetic process GO:0044283 124 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
regulation of immune system process GO:0002682 123 0.012
regeneration GO:0031099 163 0.012
protein complex subunit organization GO:0071822 302 0.012
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.012
negative regulation of innate immune response GO:0045824 4 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
regulation of ion homeostasis GO:2000021 63 0.012
developmental growth GO:0048589 100 0.012
actin cytoskeleton organization GO:0030036 73 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.011
organic acid transport GO:0015849 116 0.011
single organism catabolic process GO:0044712 283 0.011
regulation of erk1 and erk2 cascade GO:0070372 41 0.011
synaptic transmission gabaergic GO:0051932 22 0.011
positive regulation of muscle contraction GO:0045933 22 0.011
chromosome segregation GO:0007059 2 0.011
sex differentiation GO:0007548 113 0.011
innate immune response GO:0045087 35 0.011
regulation of actin filament based process GO:0032970 42 0.011
calcium ion transmembrane transport GO:0070588 70 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
regulation of catabolic process GO:0009894 113 0.011
embryonic axis specification GO:0000578 1 0.011
response to corticosteroid GO:0031960 235 0.011
insulin secretion GO:0030073 69 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
response to activity GO:0014823 73 0.011
spermatogenesis GO:0007283 99 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
muscle cell proliferation GO:0033002 84 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
response to vitamin GO:0033273 131 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
cellular amino acid metabolic process GO:0006520 107 0.011
rna localization GO:0006403 4 0.011
cellular response to monosaccharide stimulus GO:0071326 67 0.010
regulation of smooth muscle cell proliferation GO:0048660 75 0.010
cellular catabolic process GO:0044248 295 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
response to cytokine GO:0034097 215 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.010
epithelial cell differentiation GO:0030855 71 0.010
response to reactive oxygen species GO:0000302 120 0.010
positive regulation of protein modification process GO:0031401 142 0.010
actin filament based movement GO:0030048 16 0.010
embryo development GO:0009790 49 0.010
rho protein signal transduction GO:0007266 11 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.010
tongue morphogenesis GO:0043587 3 0.010
axonogenesis GO:0007409 71 0.010
phasic smooth muscle contraction GO:0014821 3 0.010
transmembrane transport GO:0055085 412 0.010

Chrna5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.012