Rattus norvegicus

76 known processes

Bub1b

budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)

Bub1b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
mitotic sister chromatid separation GO:0051306 1 0.321
chromosome segregation GO:0007059 2 0.275
metaphase anaphase transition of cell cycle GO:0044784 1 0.221
meiosis i GO:0007127 2 0.195
regulation of proteasomal protein catabolic process GO:0061136 4 0.174
protein complex assembly GO:0006461 263 0.156
organelle organization GO:0006996 266 0.142
regulation of chromosome segregation GO:0051983 1 0.122
catabolic process GO:0009056 351 0.121
meiotic cell cycle process GO:1903046 3 0.116
carboxylic acid metabolic process GO:0019752 289 0.115
regulation of mitotic sister chromatid separation GO:0010965 1 0.103
macromolecular complex subunit organization GO:0043933 339 0.102
negative regulation of rna biosynthetic process GO:1902679 118 0.101
macromolecular complex assembly GO:0065003 273 0.100
protein complex biogenesis GO:0070271 263 0.098
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.091
mitotic cell cycle phase transition GO:0044772 20 0.089
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.089
rna metabolic process GO:0016070 406 0.084
regulation of phosphorus metabolic process GO:0051174 349 0.081
mitotic sister chromatid segregation GO:0000070 1 0.079
cellular response to stress GO:0033554 269 0.078
cellular amino acid metabolic process GO:0006520 107 0.077
double strand break repair GO:0006302 1 0.076
neuron differentiation GO:0030182 368 0.076
regulation of cell proliferation GO:0042127 359 0.076
negative regulation of chromosome organization GO:2001251 1 0.075
sister chromatid segregation GO:0000819 1 0.074
negative regulation of transcription dna templated GO:0045892 116 0.070
cellular ketone metabolic process GO:0042180 51 0.070
organic acid metabolic process GO:0006082 292 0.069
regulation of phosphate metabolic process GO:0019220 349 0.065
oxoacid metabolic process GO:0043436 290 0.063
response to ddt GO:0046680 1 0.062
negative regulation of macromolecule metabolic process GO:0010605 260 0.059
protein localization GO:0008104 191 0.058
spindle organization GO:0007051 2 0.057
regulation of multicellular organismal development GO:2000026 376 0.057
regulation of ubiquitin protein transferase activity GO:0051438 1 0.056
cellular component biogenesis GO:0044085 368 0.055
cellular catabolic process GO:0044248 295 0.053
cellular component assembly GO:0022607 360 0.053
negative regulation of nucleic acid templated transcription GO:1903507 117 0.052
dna metabolic process GO:0006259 96 0.052
negative regulation of gene expression GO:0010629 199 0.051
cellular amine metabolic process GO:0044106 38 0.051
proteolysis GO:0006508 175 0.049
regulation of neurogenesis GO:0050767 247 0.049
protein complex subunit organization GO:0071822 302 0.048
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.048
regulation of molecular function GO:0065009 398 0.047
negative regulation of metabolic process GO:0009892 331 0.047
cytoskeleton organization GO:0007010 111 0.046
centrosome organization GO:0051297 1 0.045
regulation of chromosome organization GO:0033044 9 0.045
intracellular signal transduction GO:0035556 314 0.044
response to estrogen GO:0043627 232 0.044
ras protein signal transduction GO:0007265 29 0.044
ubiquitin dependent protein catabolic process GO:0006511 14 0.043
regulation of phosphorylation GO:0042325 248 0.043
tube development GO:0035295 89 0.043
organophosphate metabolic process GO:0019637 370 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.042
regulation of cellular amine metabolic process GO:0033238 8 0.042
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.041
cell cycle process GO:0022402 57 0.041
single organism organelle organization GO:1902589 180 0.040
negative regulation of cell division GO:0051782 1 0.040
regulation of protein phosphorylation GO:0001932 183 0.040
organic substance catabolic process GO:1901575 316 0.039
amine metabolic process GO:0009308 38 0.039
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.039
reproductive process GO:0022414 372 0.039
reproduction GO:0000003 245 0.038
transcription dna templated GO:0006351 377 0.038
multicellular organismal reproductive process GO:0048609 233 0.038
regulation of nucleic acid templated transcription GO:1903506 380 0.037
positive regulation of multicellular organismal process GO:0051240 387 0.037
regulation of mitotic sister chromatid segregation GO:0033047 1 0.037
anterior posterior pattern specification GO:0009952 1 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.036
regulation of nervous system development GO:0051960 264 0.036
positive regulation of developmental process GO:0051094 283 0.036
programmed cell death GO:0012501 392 0.036
negative regulation of cellular biosynthetic process GO:0031327 161 0.035
regulation of protein metabolic process GO:0051246 289 0.035
multicellular organism reproduction GO:0032504 233 0.035
regulation of rna metabolic process GO:0051252 391 0.034
positive regulation of transcription dna templated GO:0045893 197 0.034
regulation of cell development GO:0060284 263 0.033
regulation of cellular component organization GO:0051128 368 0.033
single organism catabolic process GO:0044712 283 0.033
mitotic spindle organization GO:0007052 2 0.033
multi organism reproductive process GO:0044703 262 0.032
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.032
organonitrogen compound catabolic process GO:1901565 179 0.032
regulation of neuron projection development GO:0010975 161 0.032
regulation of sister chromatid segregation GO:0033045 1 0.032
cell cycle checkpoint GO:0000075 2 0.032
regulation of cell differentiation GO:0045595 320 0.032
reactive oxygen species metabolic process GO:0072593 37 0.031
macromolecule localization GO:0033036 252 0.031
cellular response to iron iii ion GO:0071283 3 0.031
cellular component movement GO:0006928 248 0.030
response to metal ion GO:0010038 253 0.030
sexual reproduction GO:0019953 148 0.030
lipid metabolic process GO:0006629 283 0.029
protein maturation GO:0051604 68 0.029
regulation of rna biosynthetic process GO:2001141 381 0.029
regulation of organelle organization GO:0033043 80 0.029
small gtpase mediated signal transduction GO:0007264 36 0.029
negative regulation of nuclear division GO:0051784 1 0.029
regulation of neuron differentiation GO:0045664 208 0.029
rna biosynthetic process GO:0032774 380 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
epithelium development GO:0060429 96 0.029
regulation of dna metabolic process GO:0051052 60 0.029
regulation of transferase activity GO:0051338 123 0.028
gland development GO:0048732 155 0.028
centrosome cycle GO:0007098 1 0.028
purine nucleoside catabolic process GO:0006152 124 0.028
developmental process involved in reproduction GO:0003006 159 0.028
neuron development GO:0048666 286 0.028
response to transition metal nanoparticle GO:1990267 122 0.028
regulation of catalytic activity GO:0050790 304 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
negative regulation of phosphorus metabolic process GO:0010563 80 0.027
chromosome organization GO:0051276 36 0.027
regulation of cell projection organization GO:0031344 175 0.027
negative regulation of cell cycle phase transition GO:1901988 4 0.026
nucleic acid templated transcription GO:0097659 379 0.026
negative regulation of cellular protein metabolic process GO:0032269 106 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
cell projection organization GO:0030030 302 0.026
purine containing compound metabolic process GO:0072521 253 0.026
chromosome separation GO:0051304 1 0.025
regulation of protein modification process GO:0031399 194 0.025
microtubule cytoskeleton organization GO:0000226 25 0.025
response to cytokine GO:0034097 215 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.024
mitotic cell cycle checkpoint GO:0007093 1 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
single organism reproductive process GO:0044702 297 0.024
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
positive regulation of phosphorylation GO:0042327 177 0.023
establishment of organelle localization GO:0051656 37 0.023
dna packaging GO:0006323 4 0.023
glycosyl compound catabolic process GO:1901658 126 0.023
nucleoside monophosphate metabolic process GO:0009123 93 0.023
cell cycle dna replication GO:0044786 1 0.023
establishment of protein localization GO:0045184 141 0.023
purine nucleoside triphosphate metabolic process GO:0009144 141 0.023
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.022
regulation of protein kinase activity GO:0045859 105 0.022
response to nutrient levels GO:0031667 370 0.022
gonad development GO:0008406 104 0.022
protein processing GO:0016485 68 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
tissue development GO:0009888 252 0.022
atp metabolic process GO:0046034 72 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.021
cell cycle phase transition GO:0044770 21 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
purine containing compound catabolic process GO:0072523 138 0.021
response to decreased oxygen levels GO:0036293 237 0.021
cellular macromolecule localization GO:0070727 122 0.021
peptidyl amino acid modification GO:0018193 126 0.021
regulation of reactive oxygen species metabolic process GO:2000377 26 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
negative regulation of developmental process GO:0051093 125 0.020
response to toxic substance GO:0009636 133 0.020
ribonucleoside triphosphate metabolic process GO:0009199 141 0.020
protein phosphorylation GO:0006468 345 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.020
aromatic compound catabolic process GO:0019439 168 0.020
negative regulation of molecular function GO:0044092 133 0.020
regulation of catabolic process GO:0009894 113 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
response to nutrient GO:0007584 248 0.020
regulation of kinase activity GO:0043549 117 0.020
response to extracellular stimulus GO:0009991 380 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
regulation of transcription dna templated GO:0006355 374 0.019
response to peptide GO:1901652 292 0.019
negative regulation of protein maturation GO:1903318 47 0.019
response to camp GO:0051591 91 0.019
tube morphogenesis GO:0035239 23 0.019
regeneration GO:0031099 163 0.019
hindbrain morphogenesis GO:0021575 2 0.019
metaphase plate congression GO:0051310 1 0.019
cell fate determination GO:0001709 2 0.019
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
negative regulation of cell death GO:0060548 229 0.018
positive regulation of gene expression GO:0010628 244 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
nucleotide catabolic process GO:0009166 139 0.018
microtubule anchoring GO:0034453 1 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
neuron projection development GO:0031175 273 0.018
purine nucleoside monophosphate metabolic process GO:0009126 84 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
heterocycle catabolic process GO:0046700 167 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
head development GO:0060322 247 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
ribonucleotide catabolic process GO:0009261 136 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
nucleoside catabolic process GO:0009164 126 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
cell cycle g2 m phase transition GO:0044839 6 0.017
brain development GO:0007420 247 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
dna integrity checkpoint GO:0031570 2 0.016
mitotic cell cycle GO:0000278 49 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
modification dependent macromolecule catabolic process GO:0043632 14 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
gamete generation GO:0007276 124 0.016
gastrulation GO:0007369 2 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
cellular macromolecule catabolic process GO:0044265 29 0.016
cellular protein localization GO:0034613 122 0.015
nucleotide metabolic process GO:0009117 279 0.015
response to inorganic substance GO:0010035 377 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
negative regulation of phosphate metabolic process GO:0045936 80 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
single organism biosynthetic process GO:0044711 342 0.015
nuclear division GO:0000280 22 0.015
embryo development GO:0009790 49 0.015
positive regulation of triglyceride metabolic process GO:0090208 4 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
cell cycle GO:0007049 101 0.015
purine nucleoside monophosphate catabolic process GO:0009128 55 0.015
chemical homeostasis GO:0048878 292 0.015
regulation of apoptotic process GO:0042981 335 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
positive regulation of nervous system development GO:0051962 178 0.015
regulation of cellular protein catabolic process GO:1903362 7 0.015
central nervous system development GO:0007417 311 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
positive regulation of proteasomal protein catabolic process GO:1901800 3 0.015
regulation of protein processing GO:0070613 50 0.015
positive regulation of cell development GO:0010720 176 0.015
regulation of ligase activity GO:0051340 3 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.015
negative regulation of stress activated mapk cascade GO:0032873 4 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
cellular protein complex assembly GO:0043623 44 0.014
maintenance of location GO:0051235 17 0.014
growth GO:0040007 165 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
response to vitamin GO:0033273 131 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 7 0.014
regulation of mrna 3 end processing GO:0031440 1 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
ribonucleoside monophosphate metabolic process GO:0009161 88 0.014
nucleoside metabolic process GO:0009116 179 0.014
regulation of dendrite development GO:0050773 59 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
reproductive structure development GO:0048608 128 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
response to ethanol GO:0045471 162 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
locomotion GO:0040011 237 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
response to peptide hormone GO:0043434 278 0.014
dephosphorylation GO:0016311 98 0.014
mitotic nuclear division GO:0007067 15 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
microtubule organizing center organization GO:0031023 1 0.013
organelle fission GO:0048285 25 0.013
cell morphogenesis GO:0000902 142 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.013
response to mechanical stimulus GO:0009612 134 0.013
homeostatic process GO:0042592 331 0.013
regulation of response to stress GO:0080134 126 0.013
morphogenesis of embryonic epithelium GO:0016331 3 0.013
response to wounding GO:0009611 254 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
response to purine containing compound GO:0014074 126 0.013
modification dependent protein catabolic process GO:0019941 14 0.013
aging GO:0007568 241 0.013
positive regulation of transferase activity GO:0051347 81 0.012
negative regulation of proteolysis GO:0045861 41 0.012
dna damage checkpoint GO:0000077 2 0.012
positive regulation of protein modification process GO:0031401 142 0.012
regulation of programmed cell death GO:0043067 341 0.012
cell cell signaling GO:0007267 335 0.012
positive regulation of molecular function GO:0044093 230 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
positive regulation of synaptic plasticity GO:0031915 3 0.012
ventricular cardiac muscle cell development GO:0055015 2 0.012
chromatin modification GO:0016568 33 0.012
vesicle mediated transport GO:0016192 181 0.012
male meiosis GO:0007140 1 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
mitotic cell cycle process GO:1903047 35 0.012
development of primary sexual characteristics GO:0045137 107 0.012
cytoskeleton dependent cytokinesis GO:0061640 2 0.012
regulation of meiotic cell cycle GO:0051445 3 0.012
cellular response to lipid GO:0071396 201 0.012
rhythmic process GO:0048511 156 0.012
organophosphate catabolic process GO:0046434 148 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
cytoplasmic transport GO:0016482 115 0.012
developmental growth GO:0048589 100 0.012
positive regulation of ligase activity GO:0051351 1 0.012
negative regulation of nervous system development GO:0051961 79 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
response to bacterium GO:0009617 200 0.012
hepaticobiliary system development GO:0061008 90 0.011
response to hypoxia GO:0001666 231 0.011
regulation of cellular response to stress GO:0080135 49 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
spermatogenesis GO:0007283 99 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 3 0.011
response to glucocorticoid GO:0051384 223 0.011
regulation of protein maturation GO:1903317 50 0.011
dna recombination GO:0006310 3 0.011
negative regulation of transport GO:0051051 136 0.011
g2 m transition of mitotic cell cycle GO:0000086 6 0.011
wound healing GO:0042060 122 0.011
negative regulation of dendritic spine development GO:0061000 3 0.011
sex differentiation GO:0007548 113 0.011
heart development GO:0007507 72 0.011
camera type eye morphogenesis GO:0048593 2 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
negative regulation of protein processing GO:0010955 47 0.010
response to oxygen levels GO:0070482 265 0.010
protein localization to chromosome centromeric region GO:0071459 1 0.010
regulation of cell cycle process GO:0010564 31 0.010
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.010
g2 dna damage checkpoint GO:0031572 1 0.010
reproductive system development GO:0061458 128 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
organelle localization GO:0051640 55 0.010

Bub1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016