Rattus norvegicus

23 known processes

Slc9a5

solute carrier family 9 (sodium/hydrogen exchanger), member 5

(Aliases: Nhe5)

Slc9a5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.272
Rat
cellular response to oxygen containing compound GO:1901701 386 0.164
Rat
negative regulation of cell death GO:0060548 229 0.156
Rat
cellular response to organonitrogen compound GO:0071417 197 0.156
Rat
protein phosphorylation GO:0006468 345 0.129
response to peptide hormone GO:0043434 278 0.124
Rat
intracellular signal transduction GO:0035556 314 0.120
Rat
reproductive process GO:0022414 372 0.114
negative regulation of metabolic process GO:0009892 331 0.100
monovalent inorganic cation transport GO:0015672 172 0.088
carbohydrate derivative metabolic process GO:1901135 346 0.086
ion transmembrane transport GO:0034220 365 0.086
regulation of programmed cell death GO:0043067 341 0.086
Rat
ion homeostasis GO:0050801 212 0.086
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.085
multicellular organism reproduction GO:0032504 233 0.085
regulation of protein kinase activity GO:0045859 105 0.083
regulation of phosphorus metabolic process GO:0051174 349 0.083
organophosphate metabolic process GO:0019637 370 0.080
homeostatic process GO:0042592 331 0.077
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.076
regulation of molecular function GO:0065009 398 0.075
cellular response to abiotic stimulus GO:0071214 85 0.074
Rat
regulation of cellular localization GO:0060341 263 0.073
regulation of hormone secretion GO:0046883 106 0.073
cellular response to peptide hormone stimulus GO:0071375 120 0.073
Rat
response to inorganic substance GO:0010035 377 0.072
anatomical structure morphogenesis GO:0009653 298 0.071
response to peptide GO:1901652 292 0.071
Rat
regulation of phosphorylation GO:0042325 248 0.070
regulation of phosphate metabolic process GO:0019220 349 0.068
divalent inorganic cation homeostasis GO:0072507 165 0.066
programmed cell death GO:0012501 392 0.064
Rat
chemical homeostasis GO:0048878 292 0.063
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.063
sterol catabolic process GO:0016127 1 0.063
regulation of apoptotic process GO:0042981 335 0.061
Rat
cellular component movement GO:0006928 248 0.061
Rat
cellular response to hormone stimulus GO:0032870 247 0.059
Rat
locomotion GO:0040011 237 0.059
positive regulation of signaling GO:0023056 270 0.059
Rat
neuron differentiation GO:0030182 368 0.059
negative regulation of apoptotic process GO:0043066 181 0.059
Rat
response to carbohydrate GO:0009743 183 0.058
reproduction GO:0000003 245 0.055
negative regulation of transport GO:0051051 136 0.053
central nervous system development GO:0007417 311 0.053
nucleic acid templated transcription GO:0097659 379 0.053
regulation of kinase activity GO:0043549 117 0.052
cytosolic calcium ion homeostasis GO:0051480 140 0.052
response to extracellular stimulus GO:0009991 380 0.051
regulation of multicellular organismal development GO:2000026 376 0.051
organ regeneration GO:0031100 101 0.050
metal ion homeostasis GO:0055065 186 0.050
cellular response to insulin stimulus GO:0032869 81 0.049
Rat
inorganic ion transmembrane transport GO:0098660 229 0.049
cellular response to nitrogen compound GO:1901699 210 0.049
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.049
positive regulation of phosphate metabolic process GO:0045937 262 0.048
head development GO:0060322 247 0.048
regulation of peptide secretion GO:0002791 82 0.048
cellular homeostasis GO:0019725 252 0.047
Rat
single organism reproductive process GO:0044702 297 0.047
negative regulation of multicellular organismal process GO:0051241 203 0.046
ribose phosphate metabolic process GO:0019693 235 0.046
rna metabolic process GO:0016070 406 0.045
regulation of transferase activity GO:0051338 123 0.045
positive regulation of signal transduction GO:0009967 175 0.044
Rat
negative regulation of phosphate metabolic process GO:0045936 80 0.044
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.044
response to insulin GO:0032868 133 0.044
Rat
response to decreased oxygen levels GO:0036293 237 0.043
Rat
regulation of peptide transport GO:0090087 87 0.043
negative regulation of macromolecule metabolic process GO:0010605 260 0.042
hormone secretion GO:0046879 115 0.041
calcium ion homeostasis GO:0055074 162 0.041
cellular response to external stimulus GO:0071496 118 0.041
regulation of cellular component organization GO:0051128 368 0.040
Rat
regulation of peptide hormone secretion GO:0090276 80 0.040
cation transport GO:0006812 382 0.040
nucleoside metabolic process GO:0009116 179 0.040
regulation of cell differentiation GO:0045595 320 0.040
cellular ketone metabolic process GO:0042180 51 0.039
regulation of hormone levels GO:0010817 187 0.039
response to monosaccharide GO:0034284 159 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
regulation of catalytic activity GO:0050790 304 0.038
purine nucleotide metabolic process GO:0006163 229 0.038
transcription dna templated GO:0006351 377 0.037
cell morphogenesis GO:0000902 142 0.037
negative regulation of biosynthetic process GO:0009890 168 0.037
negative regulation of programmed cell death GO:0043069 183 0.037
Rat
cellular calcium ion homeostasis GO:0006874 160 0.036
cellular chemical homeostasis GO:0055082 247 0.036
Rat
regulation of transcription dna templated GO:0006355 374 0.036
cellular response to stress GO:0033554 269 0.035
Rat
potassium ion transport GO:0006813 97 0.035
nucleotide metabolic process GO:0009117 279 0.035
regulation of cell proliferation GO:0042127 359 0.035
positive regulation of peptide secretion GO:0002793 52 0.035
response to hexose GO:0009746 144 0.035
regulation of neurogenesis GO:0050767 247 0.034
response to estrogen GO:0043627 232 0.034
tissue development GO:0009888 252 0.033
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
positive regulation of multicellular organismal process GO:0051240 387 0.033
positive regulation of cell proliferation GO:0008284 249 0.033
positive regulation of biosynthetic process GO:0009891 319 0.032
catabolic process GO:0009056 351 0.032
cell projection morphogenesis GO:0048858 123 0.032
nucleoside phosphate catabolic process GO:1901292 140 0.032
multi organism reproductive process GO:0044703 262 0.032
cell projection organization GO:0030030 302 0.032
cellular divalent inorganic cation homeostasis GO:0072503 162 0.031
regulation of cellular component movement GO:0051270 150 0.031
regulation of intracellular signal transduction GO:1902531 218 0.031
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
cell cell signaling GO:0007267 335 0.030
peptide transport GO:0015833 97 0.030
secretion GO:0046903 307 0.030
cellular ion homeostasis GO:0006873 184 0.030
Rat
positive regulation of secretion GO:0051047 140 0.030
negative regulation of protein phosphorylation GO:0001933 44 0.030
negative regulation of response to stimulus GO:0048585 155 0.030
regulation of establishment of planar polarity GO:0090175 2 0.030
multicellular organismal reproductive process GO:0048609 233 0.029
positive regulation of transport GO:0051050 245 0.029
lipid metabolic process GO:0006629 283 0.029
negative regulation of glutamate secretion GO:0014050 9 0.028
gliogenesis GO:0042063 93 0.028
nucleoside triphosphate metabolic process GO:0009141 144 0.028
regulation of ion transport GO:0043269 245 0.028
Rat
metal ion transport GO:0030001 289 0.028
cation homeostasis GO:0055080 195 0.028
Rat
organic substance catabolic process GO:1901575 316 0.027
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.027
anion transmembrane transport GO:0098656 77 0.027
positive regulation of nucleotide metabolic process GO:0045981 91 0.027
cellular cation homeostasis GO:0030003 180 0.027
Rat
forebrain development GO:0030900 98 0.027
purine containing compound metabolic process GO:0072521 253 0.027
regulation of cell development GO:0060284 263 0.026
single organism catabolic process GO:0044712 283 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
ribonucleotide metabolic process GO:0009259 231 0.026
brain development GO:0007420 247 0.025
circadian rhythm GO:0007623 88 0.025
Rat
regulation of secretion GO:0051046 224 0.025
cell part morphogenesis GO:0032990 123 0.025
regulation of protein phosphorylation GO:0001932 183 0.025
peptide secretion GO:0002790 86 0.024
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
phasic smooth muscle contraction GO:0014821 3 0.024
nitrogen compound transport GO:0071705 229 0.024
cellular catabolic process GO:0044248 295 0.024
regulation of protein metabolic process GO:0051246 289 0.024
neuron development GO:0048666 286 0.024
positive regulation of developmental process GO:0051094 283 0.024
neuron projection morphogenesis GO:0048812 122 0.024
axon development GO:0061564 96 0.024
regulation of metal ion transport GO:0010959 118 0.023
Rat
hormone transport GO:0009914 121 0.023
organophosphate catabolic process GO:0046434 148 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
cyclic nucleotide biosynthetic process GO:0009190 63 0.023
negative regulation of secretion GO:0051048 82 0.023
adult locomotory behavior GO:0008344 4 0.023
protein complex biogenesis GO:0070271 263 0.023
neuron projection development GO:0031175 273 0.023
response to hypoxia GO:0001666 231 0.023
Rat
cellular component assembly GO:0022607 360 0.023
cellular component biogenesis GO:0044085 368 0.023
ribonucleoside metabolic process GO:0009119 174 0.023
mapk cascade GO:0000165 140 0.023
response to glucose GO:0009749 136 0.023
response to growth factor GO:0070848 189 0.022
sexual reproduction GO:0019953 148 0.022
glial cell differentiation GO:0010001 65 0.022
feeding behavior GO:0007631 53 0.022
regulation of nervous system development GO:0051960 264 0.022
calcium ion transport GO:0006816 131 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
purine nucleotide biosynthetic process GO:0006164 83 0.021
response to nutrient levels GO:0031667 370 0.021
negative regulation of protein metabolic process GO:0051248 114 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.021
single organism organelle organization GO:1902589 180 0.021
Rat
regulation of locomotion GO:0040012 148 0.021
regulation of muscle contraction GO:0006937 53 0.021
carbohydrate derivative biosynthetic process GO:1901137 124 0.021
protein complex assembly GO:0006461 263 0.021
regulation of insulin secretion GO:0050796 65 0.021
organophosphate biosynthetic process GO:0090407 143 0.021
glycosyl compound metabolic process GO:1901657 182 0.021
amide transport GO:0042886 105 0.021
carboxylic acid transport GO:0046942 115 0.021
steroid biosynthetic process GO:0006694 48 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
purine containing compound biosynthetic process GO:0072522 85 0.020
signal release GO:0023061 145 0.020
cell migration GO:0016477 197 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
regulation of erk1 and erk2 cascade GO:0070372 41 0.020
nucleoside phosphate biosynthetic process GO:1901293 102 0.020
regulation of neuron projection development GO:0010975 161 0.019
cellular response to peptide GO:1901653 133 0.019
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.019
regulation of protein modification process GO:0031399 194 0.019
regulation of mapk cascade GO:0043408 116 0.019
cardiovascular system development GO:0072358 134 0.019
activation of mapkk activity GO:0000186 18 0.019
protein oligomerization GO:0051259 191 0.019
neuron death GO:0070997 127 0.019
Rat
response to oxidative stress GO:0006979 186 0.019
nucleoside catabolic process GO:0009164 126 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
purine ribonucleotide biosynthetic process GO:0009152 81 0.018
regulation of calcium ion transport GO:0051924 77 0.018
dephosphorylation GO:0016311 98 0.018
cell cycle GO:0007049 101 0.018
response to oxygen levels GO:0070482 265 0.018
Rat
negative regulation of protein modification process GO:0031400 52 0.018
negative regulation of phosphorylation GO:0042326 57 0.018
cellular amine metabolic process GO:0044106 38 0.018
cellular response to mechanical stimulus GO:0071260 48 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
negative regulation of signaling GO:0023057 157 0.018
action potential GO:0001508 54 0.018
Rat
spermatogenesis GO:0007283 99 0.018
response to metal ion GO:0010038 253 0.018
apoptotic process GO:0006915 381 0.018
Rat
positive regulation of growth GO:0045927 55 0.018
Rat
regulation of signal transduction GO:0009966 318 0.018
Rat
regulation of axonogenesis GO:0050770 37 0.018
male gamete generation GO:0048232 99 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
carbohydrate homeostasis GO:0033500 75 0.018
glycosyl compound catabolic process GO:1901658 126 0.017
regulation of cell projection organization GO:0031344 175 0.017
response to ammonium ion GO:0060359 71 0.017
renal system process GO:0003014 40 0.017
response to acid chemical GO:0001101 222 0.017
regulation of neuron death GO:1901214 115 0.017
gamete generation GO:0007276 124 0.017
ribose phosphate biosynthetic process GO:0046390 87 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
cellular response to lipid GO:0071396 201 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
negative regulation of hormone secretion GO:0046888 46 0.017
purine nucleoside triphosphate metabolic process GO:0009144 141 0.017
nucleotide catabolic process GO:0009166 139 0.016
negative regulation of transcription dna templated GO:0045892 116 0.016
secretion by cell GO:0032940 248 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
guanosine containing compound catabolic process GO:1901069 71 0.016
response to vitamin GO:0033273 131 0.016
amine metabolic process GO:0009308 38 0.016
blood circulation GO:0008015 183 0.016
Rat
regulation of membrane potential GO:0042391 110 0.016
Rat
small gtpase mediated signal transduction GO:0007264 36 0.016
positive regulation of kinase activity GO:0033674 77 0.016
response to camp GO:0051591 91 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
cell activation GO:0001775 97 0.015
negative regulation of phosphorus metabolic process GO:0010563 80 0.015
cyclic nucleotide metabolic process GO:0009187 80 0.015
epithelium development GO:0060429 96 0.015
steroid metabolic process GO:0008202 73 0.015
erk1 and erk2 cascade GO:0070371 48 0.015
cellular response to acid chemical GO:0071229 75 0.015
negative regulation of molecular function GO:0044092 133 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
gland development GO:0048732 155 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.014
purine containing compound catabolic process GO:0072523 138 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
organ morphogenesis GO:0009887 75 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
sequestering of calcium ion GO:0051208 8 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
activation of protein kinase activity GO:0032147 47 0.014
cellular carbohydrate metabolic process GO:0044262 72 0.014
negative regulation of secretion by cell GO:1903531 72 0.014
sequestering of metal ion GO:0051238 9 0.014
ras protein signal transduction GO:0007265 29 0.014
regulation of cell motility GO:2000145 131 0.014
positive regulation of gene expression GO:0010628 244 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
positive regulation of cell communication GO:0010647 271 0.014
Rat
epithelial cell differentiation GO:0030855 71 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
activation of phospholipase d activity GO:0031584 2 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
regulation of secretion by cell GO:1903530 208 0.013
positive regulation of mast cell activation GO:0033005 4 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
macromolecular complex assembly GO:0065003 273 0.013
regulation of body fluid levels GO:0050878 90 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
single organism biosynthetic process GO:0044711 342 0.013
regulation of catabolic process GO:0009894 113 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
heterocycle catabolic process GO:0046700 167 0.013
inflammatory response GO:0006954 150 0.013
response to ketone GO:1901654 182 0.013
cellular response to hexose stimulus GO:0071331 65 0.012
actin filament based process GO:0030029 86 0.012
Rat
response to hydrogen peroxide GO:0042542 89 0.012
response to hyperoxia GO:0055093 45 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
Rat
peptide hormone secretion GO:0030072 84 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
response to cytokine GO:0034097 215 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
protein complex subunit organization GO:0071822 302 0.012
glutamate receptor signaling pathway GO:0007215 43 0.012
cell growth GO:0016049 104 0.012
Rat
positive regulation of rna metabolic process GO:0051254 203 0.012
jak stat cascade GO:0007259 26 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
regulation of rna metabolic process GO:0051252 391 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
regulation of inflammatory response GO:0050727 48 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
response to increased oxygen levels GO:0036296 45 0.011
response to other organism GO:0051707 220 0.011
positive regulation of protein modification process GO:0031401 142 0.011
cellular response to magnesium ion GO:0071286 4 0.011
bile acid biosynthetic process GO:0006699 3 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
response to morphine GO:0043278 27 0.011
positive regulation of transferase activity GO:0051347 81 0.011
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.011
axonogenesis GO:0007409 71 0.011
camp metabolic process GO:0046058 63 0.011
cellular amino acid metabolic process GO:0006520 107 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
regulation of cell migration GO:0030334 128 0.011
glucose homeostasis GO:0042593 75 0.011
negative regulation of organic acid transport GO:0032891 14 0.011
multicellular organism growth GO:0035264 1 0.011
anion transport GO:0006820 178 0.011
rhythmic process GO:0048511 156 0.011
Rat
negative regulation of cell proliferation GO:0008285 119 0.011
response to cocaine GO:0042220 39 0.011
sensory perception of bitter taste GO:0050913 4 0.010
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.010
response to temperature stimulus GO:0009266 94 0.010
cellular response to carbohydrate stimulus GO:0071322 72 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
positive regulation of response to stimulus GO:0048584 285 0.010
Rat
response to purine containing compound GO:0014074 126 0.010
regulation of lipid biosynthetic process GO:0046890 38 0.010
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
negative regulation of cell communication GO:0010648 158 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
positive regulation of cellular amine metabolic process GO:0033240 3 0.010
insulin secretion GO:0030073 69 0.010
intracellular transport GO:0046907 185 0.010
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
positive regulation of rna biosynthetic process GO:1902680 197 0.010

Slc9a5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032