Rattus norvegicus

0 known processes

Pitrm1

pitrilysin metallopeptidase 1

Pitrm1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein complex biogenesis GO:0070271 263 0.080
macromolecular complex subunit organization GO:0043933 339 0.074
protein complex assembly GO:0006461 263 0.071
protein complex subunit organization GO:0071822 302 0.066
organophosphate metabolic process GO:0019637 370 0.066
cellular component assembly GO:0022607 360 0.061
cellular component biogenesis GO:0044085 368 0.058
carboxylic acid metabolic process GO:0019752 289 0.057
cellular response to stress GO:0033554 269 0.054
regulation of phosphorus metabolic process GO:0051174 349 0.053
programmed cell death GO:0012501 392 0.053
nucleoside phosphate metabolic process GO:0006753 283 0.051
apoptotic process GO:0006915 381 0.050
regulation of apoptotic process GO:0042981 335 0.047
response to extracellular stimulus GO:0009991 380 0.047
homeostatic process GO:0042592 331 0.046
organic acid metabolic process GO:0006082 292 0.045
response to oxygen levels GO:0070482 265 0.044
macromolecular complex assembly GO:0065003 273 0.044
oxoacid metabolic process GO:0043436 290 0.043
intracellular signal transduction GO:0035556 314 0.041
lipid metabolic process GO:0006629 283 0.041
organelle organization GO:0006996 266 0.038
response to nutrient levels GO:0031667 370 0.038
single organism biosynthetic process GO:0044711 342 0.037
regulation of multicellular organismal development GO:2000026 376 0.036
regulation of phosphate metabolic process GO:0019220 349 0.036
single organism organelle organization GO:1902589 180 0.036
negative regulation of metabolic process GO:0009892 331 0.034
regulation of programmed cell death GO:0043067 341 0.034
regulation of signal transduction GO:0009966 318 0.034
central nervous system development GO:0007417 311 0.033
regulation of catalytic activity GO:0050790 304 0.033
macromolecule localization GO:0033036 252 0.033
rna biosynthetic process GO:0032774 380 0.032
nucleotide metabolic process GO:0009117 279 0.032
response to decreased oxygen levels GO:0036293 237 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
regulation of cellular component organization GO:0051128 368 0.031
response to inorganic substance GO:0010035 377 0.031
negative regulation of cell death GO:0060548 229 0.031
ribonucleotide metabolic process GO:0009259 231 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
negative regulation of apoptotic process GO:0043066 181 0.030
neuron differentiation GO:0030182 368 0.030
tissue development GO:0009888 252 0.030
cellular homeostasis GO:0019725 252 0.030
response to estrogen GO:0043627 232 0.029
positive regulation of cell proliferation GO:0008284 249 0.029
regulation of molecular function GO:0065009 398 0.029
glycosyl compound metabolic process GO:1901657 182 0.029
cellular amino acid metabolic process GO:0006520 107 0.028
ion transmembrane transport GO:0034220 365 0.028
purine containing compound metabolic process GO:0072521 253 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
response to hypoxia GO:0001666 231 0.028
negative regulation of programmed cell death GO:0043069 183 0.027
cellular ketone metabolic process GO:0042180 51 0.027
cellular response to hormone stimulus GO:0032870 247 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.027
regulation of cell differentiation GO:0045595 320 0.027
single organism reproductive process GO:0044702 297 0.027
positive regulation of molecular function GO:0044093 230 0.027
carbohydrate derivative metabolic process GO:1901135 346 0.027
cellular amine metabolic process GO:0044106 38 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
response to carbohydrate GO:0009743 183 0.025
amine metabolic process GO:0009308 38 0.025
neuron projection development GO:0031175 273 0.025
protein phosphorylation GO:0006468 345 0.025
positive regulation of catalytic activity GO:0043085 184 0.024
nucleic acid templated transcription GO:0097659 379 0.024
transcription dna templated GO:0006351 377 0.024
regulation of phosphorylation GO:0042325 248 0.024
neuron development GO:0048666 286 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
protein oligomerization GO:0051259 191 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
response to metal ion GO:0010038 253 0.024
head development GO:0060322 247 0.024
regulation of protein metabolic process GO:0051246 289 0.023
vesicle mediated transport GO:0016192 181 0.023
response to wounding GO:0009611 254 0.023
organonitrogen compound biosynthetic process GO:1901566 167 0.023
response to growth factor GO:0070848 189 0.023
nucleoside triphosphate metabolic process GO:0009141 144 0.023
regulation of nervous system development GO:0051960 264 0.022
regulation of cell proliferation GO:0042127 359 0.022
chemical homeostasis GO:0048878 292 0.022
negative regulation of response to stimulus GO:0048585 155 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
positive regulation of developmental process GO:0051094 283 0.021
positive regulation of signaling GO:0023056 270 0.021
secretion GO:0046903 307 0.020
aging GO:0007568 241 0.020
positive regulation of cell development GO:0010720 176 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
positive regulation of cell death GO:0010942 184 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
rhythmic process GO:0048511 156 0.019
regulation of neuron differentiation GO:0045664 208 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
cellular component morphogenesis GO:0032989 155 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
protein heterooligomerization GO:0051291 89 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
rna metabolic process GO:0016070 406 0.019
response to acid chemical GO:0001101 222 0.019
regulation of response to external stimulus GO:0032101 106 0.019
response to external biotic stimulus GO:0043207 221 0.019
cellular lipid metabolic process GO:0044255 208 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
cell projection organization GO:0030030 302 0.019
response to corticosteroid GO:0031960 235 0.019
transmembrane transport GO:0055085 412 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
regulation of membrane potential GO:0042391 110 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
cellular chemical homeostasis GO:0055082 247 0.018
positive regulation of nervous system development GO:0051962 178 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
purine containing compound catabolic process GO:0072523 138 0.017
gastrulation GO:0007369 2 0.017
response to nutrient GO:0007584 248 0.017
response to reactive oxygen species GO:0000302 120 0.017
circulatory system development GO:0072359 134 0.017
neuron projection morphogenesis GO:0048812 122 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
regulation of hydrolase activity GO:0051336 143 0.017
response to hexose GO:0009746 144 0.017
regulation of neurogenesis GO:0050767 247 0.017
brain development GO:0007420 247 0.017
cation transport GO:0006812 382 0.017
organophosphate biosynthetic process GO:0090407 143 0.017
regulation of cell development GO:0060284 263 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
negative regulation of cell communication GO:0010648 158 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
ras protein signal transduction GO:0007265 29 0.016
actin filament based process GO:0030029 86 0.016
catabolic process GO:0009056 351 0.016
organic substance catabolic process GO:1901575 316 0.016
response to temperature stimulus GO:0009266 94 0.016
response to glucose GO:0009749 136 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
response to ethanol GO:0045471 162 0.016
regulation of rna metabolic process GO:0051252 391 0.016
cell part morphogenesis GO:0032990 123 0.016
response to peptide hormone GO:0043434 278 0.016
response to ketone GO:1901654 182 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.016
response to oxidative stress GO:0006979 186 0.016
single organism catabolic process GO:0044712 283 0.016
response to hydrogen peroxide GO:0042542 89 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
regulation of cell projection organization GO:0031344 175 0.016
multicellular organism growth GO:0035264 1 0.016
oxidation reduction process GO:0055114 304 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
cell morphogenesis GO:0000902 142 0.015
cardiovascular system development GO:0072358 134 0.015
metal ion homeostasis GO:0055065 186 0.015
cation homeostasis GO:0055080 195 0.015
positive regulation of cell communication GO:0010647 271 0.015
response to glucocorticoid GO:0051384 223 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
energy derivation by oxidation of organic compounds GO:0015980 46 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
cytoskeleton organization GO:0007010 111 0.015
regulation of rna biosynthetic process GO:2001141 381 0.015
developmental process involved in reproduction GO:0003006 159 0.015
cell cell signaling GO:0007267 335 0.015
protein processing GO:0016485 68 0.015
cellular catabolic process GO:0044248 295 0.015
negative regulation of signaling GO:0023057 157 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
reproductive process GO:0022414 372 0.015
response to bacterium GO:0009617 200 0.014
regulation of neuron projection development GO:0010975 161 0.014
peptidyl amino acid modification GO:0018193 126 0.014
cellular response to lipid GO:0071396 201 0.014
reproduction GO:0000003 245 0.014
regulation of neuron death GO:1901214 115 0.014
response to biotic stimulus GO:0009607 226 0.014
regulation of anatomical structure size GO:0090066 135 0.014
response to monosaccharide GO:0034284 159 0.014
regulation of cellular localization GO:0060341 263 0.014
growth GO:0040007 165 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
mitochondrial rna metabolic process GO:0000959 1 0.014
response to other organism GO:0051707 220 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
cellular cation homeostasis GO:0030003 180 0.013
generation of precursor metabolites and energy GO:0006091 62 0.013
cellular component movement GO:0006928 248 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
response to lipopolysaccharide GO:0032496 191 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
response to toxic substance GO:0009636 133 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
negative regulation of gene expression GO:0010629 199 0.013
female pregnancy GO:0007565 122 0.013
metal ion transport GO:0030001 289 0.013
positive regulation of gene expression GO:0010628 244 0.013
proteolysis GO:0006508 175 0.013
positive regulation of signal transduction GO:0009967 175 0.013
regeneration GO:0031099 163 0.013
regulation of secretion by cell GO:1903530 208 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.013
anion transport GO:0006820 178 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
embryonic pattern specification GO:0009880 1 0.013
axis specification GO:0009798 4 0.012
immune system process GO:0002376 204 0.012
endocytosis GO:0006897 84 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
cell type specific apoptotic process GO:0097285 134 0.012
nucleoside metabolic process GO:0009116 179 0.012
multicellular organism reproduction GO:0032504 233 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
embryonic axis specification GO:0000578 1 0.012
response to peptide GO:1901652 292 0.012
muscle system process GO:0003012 115 0.012
regulation of secretion GO:0051046 224 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
defense response GO:0006952 194 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
regulation of protein modification process GO:0031399 194 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
response to starvation GO:0042594 59 0.012
anterior posterior pattern specification GO:0009952 1 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
cell projection morphogenesis GO:0048858 123 0.012
organic anion transport GO:0015711 132 0.012
intracellular transport GO:0046907 185 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
cation transmembrane transport GO:0098655 263 0.011
inflammatory response GO:0006954 150 0.011
protein localization GO:0008104 191 0.011
urogenital system development GO:0001655 78 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
dicarboxylic acid metabolic process GO:0043648 42 0.011
cellular response to external stimulus GO:0071496 118 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
neuron death GO:0070997 127 0.011
ion homeostasis GO:0050801 212 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
positive regulation of transport GO:0051050 245 0.011
negative regulation of signal transduction GO:0009968 83 0.011
response to cytokine GO:0034097 215 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
regulation of immune system process GO:0002682 123 0.011
lipid storage GO:0019915 1 0.011
secretion by cell GO:0032940 248 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
locomotion GO:0040011 237 0.011
chromosome segregation GO:0007059 2 0.011
heterocycle catabolic process GO:0046700 167 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
reproductive structure development GO:0048608 128 0.011
regulation of mapk cascade GO:0043408 116 0.011
positive regulation of cell projection organization GO:0031346 111 0.010
regulation of catabolic process GO:0009894 113 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
carbohydrate metabolic process GO:0005975 130 0.010
cell migration GO:0016477 197 0.010
negative regulation of transport GO:0051051 136 0.010
behavior GO:0007610 205 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.010
negative regulation of molecular function GO:0044092 133 0.010
response to insulin GO:0032868 133 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
multi organism reproductive process GO:0044703 262 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
alpha amino acid metabolic process GO:1901605 71 0.010
nucleoside catabolic process GO:0009164 126 0.010
regulation of response to stress GO:0080134 126 0.010
mapk cascade GO:0000165 140 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
regulation of transcription dna templated GO:0006355 374 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010

Pitrm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
musculoskeletal system disease DOID:17 0 0.030
central nervous system disease DOID:331 0 0.021
disease of metabolism DOID:0014667 0 0.018
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
inherited metabolic disorder DOID:655 0 0.013
eye disease DOID:5614 0 0.013
retinal disease DOID:5679 0 0.010