Rattus norvegicus

120 known processes

Pias1

protein inhibitor of activated STAT, 1

Pias1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.135
nucleic acid templated transcription GO:0097659 379 0.135
transcription dna templated GO:0006351 377 0.113
regulation of rna biosynthetic process GO:2001141 381 0.111
regulation of rna metabolic process GO:0051252 391 0.110
rna metabolic process GO:0016070 406 0.104
regulation of transcription dna templated GO:0006355 374 0.076
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.069
negative regulation of cellular metabolic process GO:0031324 281 0.065
protein phosphorylation GO:0006468 345 0.061
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.058
regulation of molecular function GO:0065009 398 0.054
negative regulation of metabolic process GO:0009892 331 0.052
rna biosynthetic process GO:0032774 380 0.051
regulation of phosphate metabolic process GO:0019220 349 0.050
regulation of phosphorus metabolic process GO:0051174 349 0.048
organelle organization GO:0006996 266 0.046
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.043
intracellular signal transduction GO:0035556 314 0.042
regulation of programmed cell death GO:0043067 341 0.041
reproductive process GO:0022414 372 0.041
cellular response to oxygen containing compound GO:1901701 386 0.039
single organism reproductive process GO:0044702 297 0.037
cellular amino acid metabolic process GO:0006520 107 0.036
positive regulation of phosphorus metabolic process GO:0010562 262 0.036
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.036
regulation of catalytic activity GO:0050790 304 0.036
regulation of phosphorylation GO:0042325 248 0.035
cellular amine metabolic process GO:0044106 38 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
cellular response to endogenous stimulus GO:0071495 377 0.033
regulation of cell differentiation GO:0045595 320 0.033
regulation of apoptotic process GO:0042981 335 0.033
amine metabolic process GO:0009308 38 0.032
organophosphate metabolic process GO:0019637 370 0.032
positive regulation of cell differentiation GO:0045597 217 0.032
regulation of signal transduction GO:0009966 318 0.031
cellular component assembly GO:0022607 360 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
negative regulation of gene expression GO:0010629 199 0.030
response to oxygen levels GO:0070482 265 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
negative regulation of cellular biosynthetic process GO:0031327 161 0.030
positive regulation of developmental process GO:0051094 283 0.030
positive regulation of gene expression GO:0010628 244 0.030
programmed cell death GO:0012501 392 0.030
secretion GO:0046903 307 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
homeostatic process GO:0042592 331 0.028
single organism biosynthetic process GO:0044711 342 0.028
neuron differentiation GO:0030182 368 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.028
response to hypoxia GO:0001666 231 0.027
cellular component biogenesis GO:0044085 368 0.027
apoptotic process GO:0006915 381 0.027
response to estrogen GO:0043627 232 0.027
sexual reproduction GO:0019953 148 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
positive regulation of rna metabolic process GO:0051254 203 0.027
regulation of protein phosphorylation GO:0001932 183 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
negative regulation of transcription dna templated GO:0045892 116 0.026
regulation of nervous system development GO:0051960 264 0.026
multi organism reproductive process GO:0044703 262 0.026
protein complex assembly GO:0006461 263 0.026
protein autophosphorylation GO:0046777 66 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
regulation of protein metabolic process GO:0051246 289 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.024
negative regulation of rna metabolic process GO:0051253 123 0.024
oxoacid metabolic process GO:0043436 290 0.024
negative regulation of response to stimulus GO:0048585 155 0.024
regulation of multicellular organismal development GO:2000026 376 0.023
secretion by cell GO:0032940 248 0.023
positive regulation of nervous system development GO:0051962 178 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
cellular homeostasis GO:0019725 252 0.022
positive regulation of molecular function GO:0044093 230 0.022
organic acid metabolic process GO:0006082 292 0.022
histone h3 acetylation GO:0043966 2 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
negative regulation of programmed cell death GO:0043069 183 0.021
cell cell signaling GO:0007267 335 0.021
cellular response to lipid GO:0071396 201 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
cellular ketone metabolic process GO:0042180 51 0.021
peptidyl amino acid modification GO:0018193 126 0.021
positive regulation of cell communication GO:0010647 271 0.021
chemical homeostasis GO:0048878 292 0.021
cellular response to stress GO:0033554 269 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
regulation of cell proliferation GO:0042127 359 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
cellular response to growth factor stimulus GO:0071363 162 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
single organism organelle organization GO:1902589 180 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
cell projection organization GO:0030030 302 0.019
gamete generation GO:0007276 124 0.018
response to reactive oxygen species GO:0000302 120 0.018
positive regulation of cell development GO:0010720 176 0.018
response to inorganic substance GO:0010035 377 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
multicellular organism reproduction GO:0032504 233 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
anion transport GO:0006820 178 0.018
positive regulation of signaling GO:0023056 270 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
regulation of kinase activity GO:0043549 117 0.018
protein complex biogenesis GO:0070271 263 0.018
lipid metabolic process GO:0006629 283 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
regulation of secretion by cell GO:1903530 208 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
mapk cascade GO:0000165 140 0.017
regulation of secretion GO:0051046 224 0.017
negative regulation of cell death GO:0060548 229 0.017
growth GO:0040007 165 0.016
negative regulation of cell communication GO:0010648 158 0.016
regulation of protein modification process GO:0031399 194 0.016
protein complex subunit organization GO:0071822 302 0.016
negative regulation of molecular function GO:0044092 133 0.016
axis specification GO:0009798 4 0.016
locomotion GO:0040011 237 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
response to growth factor GO:0070848 189 0.016
positive regulation of signal transduction GO:0009967 175 0.016
brain development GO:0007420 247 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
ribonucleotide metabolic process GO:0009259 231 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
neuron development GO:0048666 286 0.015
synaptic transmission GO:0007268 235 0.015
spermatogenesis GO:0007283 99 0.015
negative regulation of signal transduction GO:0009968 83 0.015
reproduction GO:0000003 245 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
cation homeostasis GO:0055080 195 0.015
response to lipopolysaccharide GO:0032496 191 0.015
macromolecular complex assembly GO:0065003 273 0.015
regulation of neurogenesis GO:0050767 247 0.014
response to nutrient levels GO:0031667 370 0.014
response to decreased oxygen levels GO:0036293 237 0.014
regulation of transferase activity GO:0051338 123 0.014
purine containing compound metabolic process GO:0072521 253 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
response to acid chemical GO:0001101 222 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
regulation of protein kinase activity GO:0045859 105 0.014
gastrulation GO:0007369 2 0.014
response to glucose GO:0009749 136 0.014
regulation of cellular localization GO:0060341 263 0.014
positive regulation of protein modification process GO:0031401 142 0.014
negative regulation of developmental process GO:0051093 125 0.014
response to peptide hormone GO:0043434 278 0.014
ras protein signal transduction GO:0007265 29 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
cellular chemical homeostasis GO:0055082 247 0.014
nucleotide metabolic process GO:0009117 279 0.014
cell morphogenesis GO:0000902 142 0.013
response to hydrogen peroxide GO:0042542 89 0.013
neuron projection development GO:0031175 273 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
multicellular organism growth GO:0035264 1 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
response to extracellular stimulus GO:0009991 380 0.013
regulation of cellular component organization GO:0051128 368 0.013
regulation of cell development GO:0060284 263 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
intracellular transport GO:0046907 185 0.013
chromatin modification GO:0016568 33 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
response to cytokine GO:0034097 215 0.013
protein oligomerization GO:0051259 191 0.013
cell type specific apoptotic process GO:0097285 134 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
organic substance catabolic process GO:1901575 316 0.012
response to peptide GO:1901652 292 0.012
response to monosaccharide GO:0034284 159 0.012
lipid storage GO:0019915 1 0.012
cellular catabolic process GO:0044248 295 0.012
negative regulation of signaling GO:0023057 157 0.012
signal release GO:0023061 145 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
cytoplasmic transport GO:0016482 115 0.012
response to carbohydrate GO:0009743 183 0.012
neurological system process GO:0050877 219 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
response to oxidative stress GO:0006979 186 0.012
anterior posterior pattern specification GO:0009952 1 0.012
sex differentiation GO:0007548 113 0.012
cellular cation homeostasis GO:0030003 180 0.012
response to organophosphorus GO:0046683 102 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
cellular ion homeostasis GO:0006873 184 0.011
positive regulation of transferase activity GO:0051347 81 0.011
response to bacterium GO:0009617 200 0.011
tube development GO:0035295 89 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
catabolic process GO:0009056 351 0.011
metal ion homeostasis GO:0055065 186 0.011
regulation of mapk cascade GO:0043408 116 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
cellular response to oxidative stress GO:0034599 76 0.011
developmental process involved in reproduction GO:0003006 159 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
response to purine containing compound GO:0014074 126 0.011
cytoskeleton organization GO:0007010 111 0.011
response to temperature stimulus GO:0009266 94 0.011
positive regulation of transport GO:0051050 245 0.011
response to ketone GO:1901654 182 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
regulation of anatomical structure size GO:0090066 135 0.011
central nervous system development GO:0007417 311 0.011
tissue development GO:0009888 252 0.010
cellular component morphogenesis GO:0032989 155 0.010
cell migration GO:0016477 197 0.010
nitrogen compound transport GO:0071705 229 0.010
nucleoside metabolic process GO:0009116 179 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
gland development GO:0048732 155 0.010
regulation of response to external stimulus GO:0032101 106 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
response to radiation GO:0009314 137 0.010
glucose homeostasis GO:0042593 75 0.010
regulation of synaptic transmission GO:0050804 141 0.010
embryonic pattern specification GO:0009880 1 0.010

Pias1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
muscular disease DOID:0080000 0 0.010
musculoskeletal system disease DOID:17 0 0.010