Rattus norvegicus

0 known processes

Loh12cr1

loss of heterozygosity, 12, chromosomal region 1 homolog (human)

Loh12cr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient levels GO:0031667 370 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.040
regulation of molecular function GO:0065009 398 0.039
rna metabolic process GO:0016070 406 0.039
response to extracellular stimulus GO:0009991 380 0.038
rna biosynthetic process GO:0032774 380 0.038
intracellular signal transduction GO:0035556 314 0.037
organophosphate metabolic process GO:0019637 370 0.036
nucleic acid templated transcription GO:0097659 379 0.036
regulation of cell differentiation GO:0045595 320 0.035
regulation of multicellular organismal development GO:2000026 376 0.034
protein phosphorylation GO:0006468 345 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.034
transcription dna templated GO:0006351 377 0.034
regulation of rna metabolic process GO:0051252 391 0.033
catabolic process GO:0009056 351 0.032
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
transcription from rna polymerase ii promoter GO:0006366 252 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
regulation of phosphate metabolic process GO:0019220 349 0.031
negative regulation of metabolic process GO:0009892 331 0.031
negative regulation of cellular metabolic process GO:0031324 281 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
regulation of catalytic activity GO:0050790 304 0.030
regulation of transcription dna templated GO:0006355 374 0.030
regulation of neurogenesis GO:0050767 247 0.030
response to inorganic substance GO:0010035 377 0.029
reproductive process GO:0022414 372 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.029
central nervous system development GO:0007417 311 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
purine containing compound metabolic process GO:0072521 253 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
neuron differentiation GO:0030182 368 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
regulation of cell development GO:0060284 263 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
ribonucleotide metabolic process GO:0009259 231 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
cellular response to stress GO:0033554 269 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.027
programmed cell death GO:0012501 392 0.026
apoptotic process GO:0006915 381 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
regulation of cellular component organization GO:0051128 368 0.026
regulation of nervous system development GO:0051960 264 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
cellular catabolic process GO:0044248 295 0.026
cellular ketone metabolic process GO:0042180 51 0.026
positive regulation of developmental process GO:0051094 283 0.026
nucleotide metabolic process GO:0009117 279 0.026
amine metabolic process GO:0009308 38 0.025
organic substance catabolic process GO:1901575 316 0.025
single organism reproductive process GO:0044702 297 0.025
cellular amine metabolic process GO:0044106 38 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
cell projection organization GO:0030030 302 0.024
negative regulation of gene expression GO:0010629 199 0.024
positive regulation of gene expression GO:0010628 244 0.024
lipid metabolic process GO:0006629 283 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
single organism catabolic process GO:0044712 283 0.024
cellular component biogenesis GO:0044085 368 0.024
regulation of apoptotic process GO:0042981 335 0.024
neuron projection development GO:0031175 273 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
organic acid metabolic process GO:0006082 292 0.023
multi organism reproductive process GO:0044703 262 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
regulation of protein metabolic process GO:0051246 289 0.023
regulation of programmed cell death GO:0043067 341 0.022
regulation of cell proliferation GO:0042127 359 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
regulation of neuron differentiation GO:0045664 208 0.022
chemical homeostasis GO:0048878 292 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
regulation of cellular localization GO:0060341 263 0.022
regulation of phosphorylation GO:0042325 248 0.022
homeostatic process GO:0042592 331 0.022
response to nutrient GO:0007584 248 0.022
response to peptide hormone GO:0043434 278 0.022
regulation of signal transduction GO:0009966 318 0.022
brain development GO:0007420 247 0.022
nitrogen compound transport GO:0071705 229 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
aging GO:0007568 241 0.021
cellular component assembly GO:0022607 360 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
positive regulation of molecular function GO:0044093 230 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
response to metal ion GO:0010038 253 0.021
neuron development GO:0048666 286 0.021
secretion GO:0046903 307 0.021
ras protein signal transduction GO:0007265 29 0.021
head development GO:0060322 247 0.021
positive regulation of cell differentiation GO:0045597 217 0.020
negative regulation of cell death GO:0060548 229 0.020
organelle organization GO:0006996 266 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
oxoacid metabolic process GO:0043436 290 0.020
protein complex biogenesis GO:0070271 263 0.020
response to external biotic stimulus GO:0043207 221 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
response to peptide GO:1901652 292 0.020
positive regulation of transcription dna templated GO:0045893 197 0.019
positive regulation of cell development GO:0010720 176 0.019
protein complex subunit organization GO:0071822 302 0.019
multicellular organism reproduction GO:0032504 233 0.019
regulation of protein modification process GO:0031399 194 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
reproduction GO:0000003 245 0.019
anterior posterior pattern specification GO:0009952 1 0.019
regulation of neuron projection development GO:0010975 161 0.019
positive regulation of nervous system development GO:0051962 178 0.019
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.019
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.019
cellular response to lipid GO:0071396 201 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
positive regulation of signaling GO:0023056 270 0.019
cation transport GO:0006812 382 0.019
tissue development GO:0009888 252 0.019
cell cell signaling GO:0007267 335 0.018
cellular component movement GO:0006928 248 0.018
protein complex assembly GO:0006461 263 0.018
response to glucocorticoid GO:0051384 223 0.018
cellular chemical homeostasis GO:0055082 247 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
neurological system process GO:0050877 219 0.018
ion transmembrane transport GO:0034220 365 0.018
macromolecular complex assembly GO:0065003 273 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
proteolysis GO:0006508 175 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
response to ketone GO:1901654 182 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
response to ethanol GO:0045471 162 0.017
response to cytokine GO:0034097 215 0.017
regulation of cell projection organization GO:0031344 175 0.017
cellular homeostasis GO:0019725 252 0.017
single organism biosynthetic process GO:0044711 342 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
heart morphogenesis GO:0003007 3 0.017
response to acid chemical GO:0001101 222 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
locomotion GO:0040011 237 0.017
response to bacterium GO:0009617 200 0.017
response to wounding GO:0009611 254 0.017
localization of cell GO:0051674 202 0.017
nucleoside metabolic process GO:0009116 179 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
transmembrane transport GO:0055085 412 0.017
heterocycle catabolic process GO:0046700 167 0.017
cell motility GO:0048870 202 0.017
response to other organism GO:0051707 220 0.017
regeneration GO:0031099 163 0.017
ribonucleoside metabolic process GO:0009119 174 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
regulation of secretion by cell GO:1903530 208 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
macromolecule localization GO:0033036 252 0.016
response to decreased oxygen levels GO:0036293 237 0.016
regulation of hormone levels GO:0010817 187 0.016
regulation of system process GO:0044057 208 0.016
negative regulation of innate immune response GO:0045824 4 0.016
response to biotic stimulus GO:0009607 226 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
cellular lipid metabolic process GO:0044255 208 0.016
protein localization GO:0008104 191 0.016
response to corticosteroid GO:0031960 235 0.016
positive regulation of cell communication GO:0010647 271 0.016
metal ion transport GO:0030001 289 0.016
synaptic transmission GO:0007268 235 0.016
cation homeostasis GO:0055080 195 0.016
growth GO:0040007 165 0.016
protein oligomerization GO:0051259 191 0.015
sexual reproduction GO:0019953 148 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
axis specification GO:0009798 4 0.015
gamete generation GO:0007276 124 0.015
regulation of secretion GO:0051046 224 0.015
ion homeostasis GO:0050801 212 0.015
response to carbohydrate GO:0009743 183 0.015
single organism organelle organization GO:1902589 180 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
aromatic compound catabolic process GO:0019439 168 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
negative regulation of signaling GO:0023057 157 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
nucleotide catabolic process GO:0009166 139 0.015
response to estrogen GO:0043627 232 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
regulation of hydrolase activity GO:0051336 143 0.015
response to oxygen levels GO:0070482 265 0.015
developmental process involved in reproduction GO:0003006 159 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
defense response GO:0006952 194 0.015
metal ion homeostasis GO:0055065 186 0.014
carbohydrate metabolic process GO:0005975 130 0.014
response to lipopolysaccharide GO:0032496 191 0.014
response to monosaccharide GO:0034284 159 0.014
regulation of catabolic process GO:0009894 113 0.014
response to hypoxia GO:0001666 231 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
gland development GO:0048732 155 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
blood circulation GO:0008015 183 0.014
maintenance of location GO:0051235 17 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
cellular ion homeostasis GO:0006873 184 0.014
vesicle mediated transport GO:0016192 181 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
negative regulation of transport GO:0051051 136 0.014
secretion by cell GO:0032940 248 0.014
positive regulation of transport GO:0051050 245 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
lipid storage GO:0019915 1 0.014
intracellular transport GO:0046907 185 0.014
anion transport GO:0006820 178 0.014
cell migration GO:0016477 197 0.014
gastrulation GO:0007369 2 0.014
ribonucleoside catabolic process GO:0042454 126 0.013
circulatory system process GO:0003013 183 0.013
single organism intracellular transport GO:1902582 166 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
response to hexose GO:0009746 144 0.013
chromosome segregation GO:0007059 2 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
response to growth factor GO:0070848 189 0.013
positive regulation of cell death GO:0010942 184 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
immune system process GO:0002376 204 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
behavior GO:0007610 205 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
cellular response to peptide GO:1901653 133 0.013
organophosphate catabolic process GO:0046434 148 0.013
oxidation reduction process GO:0055114 304 0.013
cellular cation homeostasis GO:0030003 180 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
multicellular organism growth GO:0035264 1 0.013
signal release GO:0023061 145 0.013
response to oxidative stress GO:0006979 186 0.012
embryonic pattern specification GO:0009880 1 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
positive regulation of signal transduction GO:0009967 175 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
eye morphogenesis GO:0048592 4 0.012
amide transport GO:0042886 105 0.012
purine containing compound catabolic process GO:0072523 138 0.012
rhythmic process GO:0048511 156 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
cell cycle GO:0007049 101 0.012
cytoplasmic transport GO:0016482 115 0.012
circulatory system development GO:0072359 134 0.012
positive regulation of protein modification process GO:0031401 142 0.012
response to insulin GO:0032868 133 0.012
calcium ion homeostasis GO:0055074 162 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
regulation of kinase activity GO:0043549 117 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
response to vitamin GO:0033273 131 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
regulation of anatomical structure size GO:0090066 135 0.012
response to estradiol GO:0032355 164 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
response to glucose GO:0009749 136 0.012
negative regulation of cell communication GO:0010648 158 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
cardiovascular system development GO:0072358 134 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
negative regulation of molecular function GO:0044092 133 0.012
response to radiation GO:0009314 137 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
spermatogenesis GO:0007283 99 0.011
regulation of transferase activity GO:0051338 123 0.011
nucleoside catabolic process GO:0009164 126 0.011
regulation of neuron death GO:1901214 115 0.011
vascular process in circulatory system GO:0003018 96 0.011
positive regulation of secretion GO:0051047 140 0.011
divalent inorganic cation transport GO:0072511 134 0.011
hormone transport GO:0009914 121 0.011
female pregnancy GO:0007565 122 0.011
positive regulation of tolerance induction GO:0002645 1 0.011
response to purine containing compound GO:0014074 126 0.011
male gamete generation GO:0048232 99 0.011
sex differentiation GO:0007548 113 0.011
inflammatory response GO:0006954 150 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
cell adhesion GO:0007155 110 0.011
multi multicellular organism process GO:0044706 138 0.011
negative regulation of developmental process GO:0051093 125 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
peptidyl amino acid modification GO:0018193 126 0.011
spindle organization GO:0007051 2 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
response to alkaloid GO:0043279 132 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
organ regeneration GO:0031100 101 0.011
regulation of ion transport GO:0043269 245 0.011
regulation of membrane potential GO:0042391 110 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
biological adhesion GO:0022610 110 0.011
muscle system process GO:0003012 115 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.010
ribonucleotide biosynthetic process GO:0009260 85 0.010
t cell tolerance induction GO:0002517 3 0.010
neuron death GO:0070997 127 0.010
action potential GO:0001508 54 0.010
hormone secretion GO:0046879 115 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
rho protein signal transduction GO:0007266 11 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
cellular macromolecule localization GO:0070727 122 0.010
peptide transport GO:0015833 97 0.010
reproductive structure development GO:0048608 128 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
sequestering of metal ion GO:0051238 9 0.010
gtp catabolic process GO:0006184 71 0.010
cyclic nucleotide metabolic process GO:0009187 80 0.010
lipid biosynthetic process GO:0008610 128 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
cell morphogenesis GO:0000902 142 0.010
positive regulation of hydrolase activity GO:0051345 86 0.010
neuronal action potential GO:0019228 35 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
response to toxic substance GO:0009636 133 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
rna localization GO:0006403 4 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
establishment of protein localization GO:0045184 141 0.010
neuromuscular process GO:0050905 2 0.010

Loh12cr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
musculoskeletal system disease DOID:17 0 0.016
disease of metabolism DOID:0014667 0 0.014
connective tissue disease DOID:65 0 0.012
central nervous system disease DOID:331 0 0.011
sensory system disease DOID:0050155 0 0.010