Rattus norvegicus

92 known processes

Mfn2

mitofusin 2

(Aliases: HSG)

Mfn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.282
oxoacid metabolic process GO:0043436 290 0.198
organelle organization GO:0006996 266 0.181
carboxylic acid metabolic process GO:0019752 289 0.178
catabolic process GO:0009056 351 0.137
nucleoside phosphate metabolic process GO:0006753 283 0.113
organophosphate metabolic process GO:0019637 370 0.105
nucleobase containing small molecule metabolic process GO:0055086 316 0.094
macromolecular complex subunit organization GO:0043933 339 0.093
single organism biosynthetic process GO:0044711 342 0.082
single organism catabolic process GO:0044712 283 0.080
organic substance catabolic process GO:1901575 316 0.080
coenzyme metabolic process GO:0006732 86 0.078
negative regulation of nervous system development GO:0051961 79 0.069
cellular catabolic process GO:0044248 295 0.064
mitotic spindle organization GO:0007052 2 0.061
monocarboxylic acid metabolic process GO:0032787 152 0.059
cellular component assembly GO:0022607 360 0.054
cofactor metabolic process GO:0051186 95 0.052
macromolecular complex assembly GO:0065003 273 0.052
carbohydrate derivative metabolic process GO:1901135 346 0.050
single organism organelle organization GO:1902589 180 0.049
cellular amino acid metabolic process GO:0006520 107 0.047
nitrogen compound transport GO:0071705 229 0.046
regulation of cell development GO:0060284 263 0.046
oxidation reduction process GO:0055114 304 0.043
purine nucleotide metabolic process GO:0006163 229 0.042
response to nutrient levels GO:0031667 370 0.041
regulation of multicellular organismal development GO:2000026 376 0.040
nucleotide metabolic process GO:0009117 279 0.039
cellular response to organonitrogen compound GO:0071417 197 0.037
cellular response to nitrogen compound GO:1901699 210 0.036
central nervous system development GO:0007417 311 0.036
neuron differentiation GO:0030182 368 0.036
negative regulation of neurogenesis GO:0050768 78 0.036
negative regulation of multicellular organismal process GO:0051241 203 0.036
cation transmembrane transport GO:0098655 263 0.036
response to nutrient GO:0007584 248 0.035
alpha amino acid metabolic process GO:1901605 71 0.034
regulation of nervous system development GO:0051960 264 0.034
regulation of transcription dna templated GO:0006355 374 0.034
cellular response to oxygen containing compound GO:1901701 386 0.034
regulation of protein metabolic process GO:0051246 289 0.033
cell cell signaling GO:0007267 335 0.033
signal release GO:0023061 145 0.033
response to inorganic substance GO:0010035 377 0.032
transmembrane transport GO:0055085 412 0.032
nucleobase containing compound catabolic process GO:0034655 152 0.032
cation transport GO:0006812 382 0.032
response to extracellular stimulus GO:0009991 380 0.032
carbohydrate metabolic process GO:0005975 130 0.032
response to peptide GO:1901652 292 0.031
learning or memory GO:0007611 90 0.030
regulation of apoptotic process GO:0042981 335 0.030
organic hydroxy compound metabolic process GO:1901615 115 0.030
cellular component biogenesis GO:0044085 368 0.030
purine containing compound metabolic process GO:0072521 253 0.030
spindle organization GO:0007051 2 0.030
aromatic compound catabolic process GO:0019439 168 0.029
protein complex subunit organization GO:0071822 302 0.029
regulation of cell proliferation GO:0042127 359 0.029
purine ribonucleotide metabolic process GO:0009150 227 0.029
cellular lipid metabolic process GO:0044255 208 0.029
negative regulation of cell differentiation GO:0045596 99 0.029
protein complex biogenesis GO:0070271 263 0.029
response to ketone GO:1901654 182 0.028
organophosphate catabolic process GO:0046434 148 0.028
transcription dna templated GO:0006351 377 0.028
male mating behavior GO:0060179 3 0.028
intracellular transport GO:0046907 185 0.028
response to peptide hormone GO:0043434 278 0.028
dicarboxylic acid metabolic process GO:0043648 42 0.028
negative regulation of metabolic process GO:0009892 331 0.027
anatomical structure morphogenesis GO:0009653 298 0.026
ribonucleotide metabolic process GO:0009259 231 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
single organism cellular localization GO:1902580 102 0.026
organic cyclic compound catabolic process GO:1901361 175 0.026
cell fate determination GO:0001709 2 0.025
macromolecule localization GO:0033036 252 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
protein localization GO:0008104 191 0.025
axon cargo transport GO:0008088 1 0.025
neurological system process GO:0050877 219 0.025
pyridine containing compound metabolic process GO:0072524 32 0.025
negative regulation of developmental process GO:0051093 125 0.024
cellular ketone metabolic process GO:0042180 51 0.024
programmed cell death GO:0012501 392 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
reproductive process GO:0022414 372 0.024
nucleoside phosphate catabolic process GO:1901292 140 0.024
ribonucleotide catabolic process GO:0009261 136 0.024
reproduction GO:0000003 245 0.024
negative regulation of cell development GO:0010721 82 0.023
cell cycle GO:0007049 101 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
regulation of cell differentiation GO:0045595 320 0.023
brain development GO:0007420 247 0.023
cellular amine metabolic process GO:0044106 38 0.023
cellular response to insulin stimulus GO:0032869 81 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
purine nucleoside metabolic process GO:0042278 169 0.023
regulation of rna biosynthetic process GO:2001141 381 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
secretion GO:0046903 307 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
regulation of signal transduction GO:0009966 318 0.022
nucleoside monophosphate metabolic process GO:0009123 93 0.022
intracellular signal transduction GO:0035556 314 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
ribonucleoside monophosphate metabolic process GO:0009161 88 0.021
response to acid chemical GO:0001101 222 0.021
regulation of system process GO:0044057 208 0.021
positive regulation of cell development GO:0010720 176 0.021
hormone secretion GO:0046879 115 0.021
secretion by cell GO:0032940 248 0.021
ras protein signal transduction GO:0007265 29 0.021
response to hypoxia GO:0001666 231 0.021
generation of precursor metabolites and energy GO:0006091 62 0.021
eye morphogenesis GO:0048592 4 0.021
small molecule catabolic process GO:0044282 59 0.021
response to oxygen levels GO:0070482 265 0.021
neuron projection development GO:0031175 273 0.020
anterior posterior pattern specification GO:0009952 1 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
nucleoside metabolic process GO:0009116 179 0.020
mitotic cell cycle GO:0000278 49 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
chemical homeostasis GO:0048878 292 0.020
response to monosaccharide GO:0034284 159 0.020
regulation of molecular function GO:0065009 398 0.020
multi organism reproductive process GO:0044703 262 0.020
amine metabolic process GO:0009308 38 0.020
response to metal ion GO:0010038 253 0.020
cellular macromolecular complex assembly GO:0034622 58 0.020
response to alkaloid GO:0043279 132 0.020
regulation of membrane potential GO:0042391 110 0.020
positive regulation of cell differentiation GO:0045597 217 0.019
cellular protein localization GO:0034613 122 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
multi multicellular organism process GO:0044706 138 0.019
olfactory learning GO:0008355 1 0.019
microtubule cytoskeleton organization GO:0000226 25 0.019
centrosome organization GO:0051297 1 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
microtubule organizing center organization GO:0031023 1 0.019
apoptotic process GO:0006915 381 0.019
proteolysis GO:0006508 175 0.018
positive regulation of developmental process GO:0051094 283 0.018
regulation of neurogenesis GO:0050767 247 0.018
head development GO:0060322 247 0.018
heterocycle catabolic process GO:0046700 167 0.018
regulation of hormone levels GO:0010817 187 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
cellular macromolecule localization GO:0070727 122 0.018
nucleosome organization GO:0034728 1 0.018
single organism carbohydrate metabolic process GO:0044723 118 0.018
regulation of catalytic activity GO:0050790 304 0.018
behavior GO:0007610 205 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
synaptic transmission GO:0007268 235 0.017
vesicle mediated transport GO:0016192 181 0.017
negative regulation of gene expression GO:0010629 199 0.017
neuron development GO:0048666 286 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
response to toxic substance GO:0009636 133 0.017
response to decreased oxygen levels GO:0036293 237 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
nucleoside triphosphate metabolic process GO:0009141 144 0.017
cellular response to peptide GO:1901653 133 0.017
cognition GO:0050890 92 0.017
cell projection organization GO:0030030 302 0.017
establishment of protein localization GO:0045184 141 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
defense response GO:0006952 194 0.016
cellular response to peptide hormone stimulus GO:0071375 120 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
centrosome cycle GO:0007098 1 0.016
establishment of organelle localization GO:0051656 37 0.016
cellular component movement GO:0006928 248 0.016
multicellular organismal signaling GO:0035637 44 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
nicotinamide nucleotide metabolic process GO:0046496 28 0.015
cytoskeleton organization GO:0007010 111 0.015
epithelial cell differentiation GO:0030855 71 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
response to insulin GO:0032868 133 0.015
regulation of peptide hormone secretion GO:0090276 80 0.015
epithelium development GO:0060429 96 0.015
regulation of cellular component organization GO:0051128 368 0.015
rna metabolic process GO:0016070 406 0.015
transmission of nerve impulse GO:0019226 42 0.015
chromosome segregation GO:0007059 2 0.015
regulation of secretion GO:0051046 224 0.015
metal ion transport GO:0030001 289 0.015
regulation of rna metabolic process GO:0051252 391 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
ion transmembrane transport GO:0034220 365 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
response to glucose GO:0009749 136 0.015
response to estradiol GO:0032355 164 0.014
aging GO:0007568 241 0.014
multicellular organism reproduction GO:0032504 233 0.014
liver development GO:0001889 90 0.014
response to carbohydrate GO:0009743 183 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
cellular response to stress GO:0033554 269 0.014
phospholipid metabolic process GO:0006644 61 0.014
cellular response to external stimulus GO:0071496 118 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
lipid metabolic process GO:0006629 283 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
cellular protein complex assembly GO:0043623 44 0.014
negative regulation of cell communication GO:0010648 158 0.014
regulation of neural precursor cell proliferation GO:2000177 16 0.014
embryonic pattern specification GO:0009880 1 0.014
protein complex assembly GO:0006461 263 0.014
single organism intracellular transport GO:1902582 166 0.014
chemosensory behavior GO:0007635 2 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
acetyl coa metabolic process GO:0006084 17 0.014
energy derivation by oxidation of organic compounds GO:0015980 46 0.014
regulation of cellular localization GO:0060341 263 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
gliogenesis GO:0042063 93 0.014
regulation of stem cell proliferation GO:0072091 14 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
regeneration GO:0031099 163 0.013
action potential GO:0001508 54 0.013
regulation of neuron projection development GO:0010975 161 0.013
developmental growth GO:0048589 100 0.013
carboxylic acid catabolic process GO:0046395 49 0.013
negative regulation of transport GO:0051051 136 0.013
organelle localization GO:0051640 55 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
chromosome organization GO:0051276 36 0.013
hepaticobiliary system development GO:0061008 90 0.013
growth GO:0040007 165 0.013
positive regulation of molecular function GO:0044093 230 0.013
homeostatic process GO:0042592 331 0.013
rna localization GO:0006403 4 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
hormone transport GO:0009914 121 0.013
tissue development GO:0009888 252 0.013
purine containing compound catabolic process GO:0072523 138 0.013
regulation of peptide transport GO:0090087 87 0.013
pyridine nucleotide metabolic process GO:0019362 28 0.013
positive regulation of gene expression GO:0010628 244 0.013
glutamate metabolic process GO:0006536 3 0.013
cellular homeostasis GO:0019725 252 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
peptide secretion GO:0002790 86 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
chromatin assembly or disassembly GO:0006333 1 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
immune response GO:0006955 104 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
peptide hormone secretion GO:0030072 84 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
ion homeostasis GO:0050801 212 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
multicellular organism growth GO:0035264 1 0.012
olfactory behavior GO:0042048 2 0.012
response to hexose GO:0009746 144 0.012
centrosome localization GO:0051642 1 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
aspartate family amino acid metabolic process GO:0009066 10 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
regulation of cell projection organization GO:0031344 175 0.012
protein localization to chromosome centromeric region GO:0071459 1 0.012
response to estrogen GO:0043627 232 0.012
anion transport GO:0006820 178 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.012
axis specification GO:0009798 4 0.011
glycerolipid metabolic process GO:0046486 67 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
response to radiation GO:0009314 137 0.011
cell cycle process GO:0022402 57 0.011
positive regulation of nervous system development GO:0051962 178 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
organ regeneration GO:0031100 101 0.011
regulation of programmed cell death GO:0043067 341 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
response to reactive oxygen species GO:0000302 120 0.011
response to fatty acid GO:0070542 65 0.011
embryonic skeletal system morphogenesis GO:0048704 3 0.011
memory GO:0007613 54 0.011
regulation of insulin secretion GO:0050796 65 0.011
positive regulation of signaling GO:0023056 270 0.011
gastrulation GO:0007369 2 0.011
cellular chemical homeostasis GO:0055082 247 0.011
mesoderm development GO:0007498 2 0.011
negative regulation of signaling GO:0023057 157 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.010
innate immune response GO:0045087 35 0.010
positive regulation of response to stimulus GO:0048584 285 0.010
small molecule biosynthetic process GO:0044283 124 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
peptide transport GO:0015833 97 0.010
response to wounding GO:0009611 254 0.010
cellular respiration GO:0045333 21 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
nucleic acid templated transcription GO:0097659 379 0.010

Mfn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.041
central nervous system disease DOID:331 0 0.022
musculoskeletal system disease DOID:17 0 0.012