Rattus norvegicus

0 known processes

Trim17

tripartite motif-containing 17

(Aliases: Rnf16)

Trim17 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.160
regulation of phosphorus metabolic process GO:0051174 349 0.148
anatomical structure morphogenesis GO:0009653 298 0.142
brain development GO:0007420 247 0.140
positive regulation of phosphorus metabolic process GO:0010562 262 0.135
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.132
regulation of cellular localization GO:0060341 263 0.118
regulation of hormone secretion GO:0046883 106 0.103
organophosphate metabolic process GO:0019637 370 0.101
tissue development GO:0009888 252 0.096
neuron differentiation GO:0030182 368 0.095
purine nucleotide biosynthetic process GO:0006164 83 0.092
macromolecular complex subunit organization GO:0043933 339 0.091
organic substance catabolic process GO:1901575 316 0.090
positive regulation of biosynthetic process GO:0009891 319 0.087
head development GO:0060322 247 0.083
cellular calcium ion homeostasis GO:0006874 160 0.081
macromolecular complex assembly GO:0065003 273 0.079
single organism biosynthetic process GO:0044711 342 0.077
negative regulation of transport GO:0051051 136 0.076
regulation of apoptotic process GO:0042981 335 0.074
negative regulation of cellular metabolic process GO:0031324 281 0.074
negative regulation of cellular biosynthetic process GO:0031327 161 0.073
negative regulation of apoptotic process GO:0043066 181 0.069
signal release GO:0023061 145 0.068
intracellular signal transduction GO:0035556 314 0.067
negative regulation of programmed cell death GO:0043069 183 0.066
negative regulation of gene expression GO:0010629 199 0.066
positive regulation of molecular function GO:0044093 230 0.066
regulation of intracellular signal transduction GO:1902531 218 0.064
g protein coupled receptor signaling pathway GO:0007186 242 0.064
cation homeostasis GO:0055080 195 0.062
negative regulation of metabolic process GO:0009892 331 0.062
neuron projection development GO:0031175 273 0.061
protein complex assembly GO:0006461 263 0.060
regulation of secretion GO:0051046 224 0.059
regulation of programmed cell death GO:0043067 341 0.059
cellular component morphogenesis GO:0032989 155 0.056
regulation of transcription dna templated GO:0006355 374 0.056
programmed cell death GO:0012501 392 0.052
regulation of rna biosynthetic process GO:2001141 381 0.052
hormone transport GO:0009914 121 0.051
regulation of phosphate metabolic process GO:0019220 349 0.049
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.048
neuron development GO:0048666 286 0.048
cellular cation homeostasis GO:0030003 180 0.048
cell part morphogenesis GO:0032990 123 0.047
metal ion homeostasis GO:0055065 186 0.047
cellular homeostasis GO:0019725 252 0.047
transcription from rna polymerase ii promoter GO:0006366 252 0.045
rna metabolic process GO:0016070 406 0.045
regulation of nucleotide metabolic process GO:0006140 117 0.045
organonitrogen compound biosynthetic process GO:1901566 167 0.044
apoptotic process GO:0006915 381 0.044
negative regulation of hormone secretion GO:0046888 46 0.044
homeostatic process GO:0042592 331 0.043
secretion by cell GO:0032940 248 0.043
circulatory system process GO:0003013 183 0.043
defense response GO:0006952 194 0.042
ion homeostasis GO:0050801 212 0.042
calcium ion homeostasis GO:0055074 162 0.042
regulation of rna metabolic process GO:0051252 391 0.041
central nervous system development GO:0007417 311 0.041
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
ribose phosphate metabolic process GO:0019693 235 0.041
regulation of multicellular organismal development GO:2000026 376 0.041
single organism reproductive process GO:0044702 297 0.041
locomotion GO:0040011 237 0.040
transcription dna templated GO:0006351 377 0.040
proteolysis GO:0006508 175 0.039
gastrulation GO:0007369 2 0.039
nucleotide metabolic process GO:0009117 279 0.039
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.039
localization of cell GO:0051674 202 0.039
positive regulation of response to stimulus GO:0048584 285 0.039
cellular amine metabolic process GO:0044106 38 0.038
metal ion transport GO:0030001 289 0.038
negative regulation of response to stimulus GO:0048585 155 0.038
organophosphate biosynthetic process GO:0090407 143 0.038
cytosolic calcium ion homeostasis GO:0051480 140 0.038
rna biosynthetic process GO:0032774 380 0.037
regulation of catalytic activity GO:0050790 304 0.037
regulation of cell migration GO:0030334 128 0.037
divalent inorganic cation transport GO:0072511 134 0.037
reproduction GO:0000003 245 0.036
multicellular organism reproduction GO:0032504 233 0.035
cellular component biogenesis GO:0044085 368 0.035
regulation of anatomical structure morphogenesis GO:0022603 141 0.034
nucleic acid templated transcription GO:0097659 379 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
positive regulation of cell proliferation GO:0008284 249 0.034
cellular carbohydrate metabolic process GO:0044262 72 0.034
hormone secretion GO:0046879 115 0.034
negative regulation of protein transport GO:0051224 17 0.033
cellular response to oxygen containing compound GO:1901701 386 0.033
protein complex biogenesis GO:0070271 263 0.033
single organism organelle organization GO:1902589 180 0.033
lipid metabolic process GO:0006629 283 0.033
regulation of system process GO:0044057 208 0.033
cardiovascular system development GO:0072358 134 0.032
regulation of peptide transport GO:0090087 87 0.032
positive regulation of phosphate metabolic process GO:0045937 262 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.032
catabolic process GO:0009056 351 0.032
positive regulation of phosphorylation GO:0042327 177 0.031
regulation of cellular component organization GO:0051128 368 0.031
cellular ion homeostasis GO:0006873 184 0.031
oxidation reduction process GO:0055114 304 0.031
macromolecule localization GO:0033036 252 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
cellular response to endogenous stimulus GO:0071495 377 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
divalent inorganic cation homeostasis GO:0072507 165 0.030
peptide secretion GO:0002790 86 0.030
reproductive process GO:0022414 372 0.030
secretion GO:0046903 307 0.030
cell projection organization GO:0030030 302 0.030
positive regulation of programmed cell death GO:0043068 157 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.029
regulation of hormone levels GO:0010817 187 0.029
regulation of neuron projection development GO:0010975 161 0.029
cation transport GO:0006812 382 0.029
wound healing GO:0042060 122 0.029
positive regulation of gene expression GO:0010628 244 0.029
multicellular organismal reproductive process GO:0048609 233 0.029
lipid biosynthetic process GO:0008610 128 0.028
negative regulation of biosynthetic process GO:0009890 168 0.028
cellular divalent inorganic cation homeostasis GO:0072503 162 0.028
single organism carbohydrate metabolic process GO:0044723 118 0.028
blood circulation GO:0008015 183 0.028
regulation of protein metabolic process GO:0051246 289 0.028
organelle organization GO:0006996 266 0.028
positive regulation of secretion GO:0051047 140 0.028
regulation of phosphorylation GO:0042325 248 0.027
regulation of molecular function GO:0065009 398 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
single organism catabolic process GO:0044712 283 0.027
negative regulation of rna biosynthetic process GO:1902679 118 0.027
cell morphogenesis involved in differentiation GO:0000904 119 0.027
oxoacid metabolic process GO:0043436 290 0.027
positive regulation of apoptotic process GO:0043065 154 0.026
cellular metal ion homeostasis GO:0006875 172 0.026
diencephalon development GO:0021536 21 0.026
carboxylic acid metabolic process GO:0019752 289 0.026
protein phosphorylation GO:0006468 345 0.026
axon development GO:0061564 96 0.026
regulation of metal ion transport GO:0010959 118 0.026
regulation of cell differentiation GO:0045595 320 0.025
regulation of neurogenesis GO:0050767 247 0.025
regulation of protein phosphorylation GO:0001932 183 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
regulation of peptide hormone secretion GO:0090276 80 0.025
inflammatory response GO:0006954 150 0.024
purine ribonucleotide biosynthetic process GO:0009152 81 0.024
chemical homeostasis GO:0048878 292 0.024
regulation of response to stress GO:0080134 126 0.024
positive regulation of developmental process GO:0051094 283 0.024
developmental process involved in reproduction GO:0003006 159 0.024
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
cell cell signaling GO:0007267 335 0.023
response to decreased oxygen levels GO:0036293 237 0.023
protein oligomerization GO:0051259 191 0.022
response to radiation GO:0009314 137 0.022
synaptic transmission GO:0007268 235 0.022
protein heterooligomerization GO:0051291 89 0.022
insulin secretion GO:0030073 69 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
regulation of signal transduction GO:0009966 318 0.022
multi organism reproductive process GO:0044703 262 0.022
regulation of cell proliferation GO:0042127 359 0.021
carbohydrate derivative biosynthetic process GO:1901137 124 0.021
cyclic nucleotide metabolic process GO:0009187 80 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
response to hexose GO:0009746 144 0.021
negative regulation of secretion GO:0051048 82 0.021
regulation of cell motility GO:2000145 131 0.021
cell projection morphogenesis GO:0048858 123 0.020
amine metabolic process GO:0009308 38 0.020
sexual reproduction GO:0019953 148 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
neuronal action potential GO:0019228 35 0.020
regulation of insulin secretion GO:0050796 65 0.020
cellular component movement GO:0006928 248 0.020
cellular lipid metabolic process GO:0044255 208 0.020
negative regulation of signaling GO:0023057 157 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
cell cycle GO:0007049 101 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
protein complex subunit organization GO:0071822 302 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
intracellular transport GO:0046907 185 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
regulation of catabolic process GO:0009894 113 0.019
transmission of nerve impulse GO:0019226 42 0.019
cellular protein localization GO:0034613 122 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
regulation of response to external stimulus GO:0032101 106 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
intracellular protein transport GO:0006886 79 0.018
cell motility GO:0048870 202 0.018
glucan metabolic process GO:0044042 23 0.018
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.018
cellular catabolic process GO:0044248 295 0.018
ribonucleotide biosynthetic process GO:0009260 85 0.017
organ morphogenesis GO:0009887 75 0.017
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.017
nitrogen compound transport GO:0071705 229 0.017
neuron projection morphogenesis GO:0048812 122 0.017
ovulation cycle GO:0042698 67 0.017
negative regulation of cell communication GO:0010648 158 0.017
response to ketone GO:1901654 182 0.017
cellular ketone metabolic process GO:0042180 51 0.017
nuclear transport GO:0051169 49 0.017
response to glucose GO:0009749 136 0.017
immune response GO:0006955 104 0.017
regulation of nervous system development GO:0051960 264 0.017
glucose metabolic process GO:0006006 52 0.017
positive regulation of cell communication GO:0010647 271 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
carbohydrate metabolic process GO:0005975 130 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
regulation of cell development GO:0060284 263 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.016
cell morphogenesis GO:0000902 142 0.016
l glutamate import GO:0051938 2 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
tongue morphogenesis GO:0043587 3 0.016
peptide hormone secretion GO:0030072 84 0.015
cellular component assembly GO:0022607 360 0.015
protein transport GO:0015031 132 0.015
reproductive system development GO:0061458 128 0.015
negative regulation of innate immune response GO:0045824 4 0.015
regulation of angiogenesis GO:0045765 39 0.015
phospholipid biosynthetic process GO:0008654 29 0.015
negative regulation of camp metabolic process GO:0030815 14 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
cyclic purine nucleotide metabolic process GO:0052652 62 0.015
protein import into nucleus GO:0006606 35 0.015
response to inorganic substance GO:0010035 377 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
response to estrogen GO:0043627 232 0.015
ion transmembrane transport GO:0034220 365 0.015
dna metabolic process GO:0006259 96 0.015
negative regulation of cell death GO:0060548 229 0.015
positive regulation of signal transduction GO:0009967 175 0.015
positive regulation of cell death GO:0010942 184 0.015
lipid transport GO:0006869 61 0.015
gonad development GO:0008406 104 0.015
growth GO:0040007 165 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
ribonucleotide metabolic process GO:0009259 231 0.014
regulation of membrane potential GO:0042391 110 0.014
muscle structure development GO:0061061 87 0.014
nucleotide biosynthetic process GO:0009165 98 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
response to oxygen levels GO:0070482 265 0.014
cytoplasmic transport GO:0016482 115 0.014
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.014
protein import GO:0017038 37 0.014
neuropeptide signaling pathway GO:0007218 29 0.014
protein processing GO:0016485 68 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
cellular amino acid metabolic process GO:0006520 107 0.014
mitotic cell cycle GO:0000278 49 0.014
negative regulation of secretion by cell GO:1903531 72 0.014
peptide transport GO:0015833 97 0.014
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.014
gamete generation GO:0007276 124 0.014
regulation of cell cycle GO:0051726 73 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
negative regulation of molecular function GO:0044092 133 0.014
myelination GO:0042552 39 0.014
regulation of establishment of protein localization GO:0070201 69 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
purine containing compound biosynthetic process GO:0072522 85 0.014
protein maturation GO:0051604 68 0.013
positive regulation of transport GO:0051050 245 0.013
response to purine containing compound GO:0014074 126 0.013
cofactor metabolic process GO:0051186 95 0.013
regulation of ion transport GO:0043269 245 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
sensory perception GO:0007600 101 0.013
forebrain neuron development GO:0021884 3 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
regulation of cellular component movement GO:0051270 150 0.013
vascular process in circulatory system GO:0003018 96 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
purine containing compound metabolic process GO:0072521 253 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
nuclear import GO:0051170 35 0.013
ras protein signal transduction GO:0007265 29 0.013
fertilization GO:0009566 3 0.013
cellular chemical homeostasis GO:0055082 247 0.013
axonogenesis GO:0007409 71 0.013
cellular response to oxygen levels GO:0071453 60 0.013
regulation of protein targeting GO:1903533 28 0.013
metanephric tubule morphogenesis GO:0072173 2 0.013
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
response to oxidative stress GO:0006979 186 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.012
calcium ion transport GO:0006816 131 0.012
response to estradiol GO:0032355 164 0.012
striated muscle tissue development GO:0014706 58 0.012
positive regulation of protein kinase b signaling GO:0051897 10 0.012
regulation of protein import into nucleus GO:0042306 24 0.012
sequestering of calcium ion GO:0051208 8 0.012
regulation of camp metabolic process GO:0030814 43 0.012
phospholipid metabolic process GO:0006644 61 0.012
regulation of intracellular transport GO:0032386 65 0.012
regulation of nucleotide biosynthetic process GO:0030808 47 0.012
regulation of cell projection organization GO:0031344 175 0.012
regulation of synaptic transmission GO:0050804 141 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
nucleocytoplasmic transport GO:0006913 48 0.012
cell cycle process GO:0022402 57 0.012
visual learning GO:0008542 8 0.012
regulation of g0 to g1 transition GO:0070316 3 0.012
aromatic compound catabolic process GO:0019439 168 0.012
carbohydrate biosynthetic process GO:0016051 42 0.012
negative regulation of long term synaptic potentiation GO:1900272 1 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
response to activity GO:0014823 73 0.012
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.012
peptidyl amino acid modification GO:0018193 126 0.012
circadian rhythm GO:0007623 88 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
anatomical structure homeostasis GO:0060249 29 0.012
maintenance of location GO:0051235 17 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
regulation of peptide secretion GO:0002791 82 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.011
response to hypoxia GO:0001666 231 0.011
circulatory system development GO:0072359 134 0.011
regulation of hydrolase activity GO:0051336 143 0.011
reproductive structure development GO:0048608 128 0.011
regulation of proteolysis GO:0030162 66 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
organic acid metabolic process GO:0006082 292 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
development of primary female sexual characteristics GO:0046545 56 0.011
positive regulation of organelle organization GO:0010638 48 0.011
divalent metal ion transport GO:0070838 132 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
multi multicellular organism process GO:0044706 138 0.011
regulation of cell growth GO:0001558 85 0.011
positive regulation of ion transport GO:0043270 94 0.011
regulation of dna metabolic process GO:0051052 60 0.011
fat cell proliferation GO:0070341 2 0.011
regulation of organelle organization GO:0033043 80 0.011
single organism nuclear import GO:1902593 35 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
coronary vasculature morphogenesis GO:0060977 3 0.011
regulation of organ formation GO:0003156 2 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
tolerance induction dependent upon immune response GO:0002461 2 0.011
generation of precursor metabolites and energy GO:0006091 62 0.011
developmental induction GO:0031128 2 0.011
amide transport GO:0042886 105 0.011
regulation of blood circulation GO:1903522 110 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
cellular polysaccharide metabolic process GO:0044264 23 0.011
single organism intracellular transport GO:1902582 166 0.011
spermatogenesis GO:0007283 99 0.011
regulation of epithelial cell proliferation GO:0050678 49 0.010
cellular response to stress GO:0033554 269 0.010
endoplasmic reticulum membrane organization GO:0090158 1 0.010
negative regulation of intracellular signal transduction GO:1902532 38 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
organic hydroxy compound biosynthetic process GO:1901617 51 0.010
regulation of cellular protein metabolic process GO:0032268 267 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
phototransduction visible light GO:0007603 2 0.010
cellular macromolecule localization GO:0070727 122 0.010
epithelial cell proliferation GO:0050673 54 0.010
skeletal system development GO:0001501 41 0.010
neurological system process GO:0050877 219 0.010
transmembrane transport GO:0055085 412 0.010
glandular epithelial cell differentiation GO:0002067 4 0.010
cyclic nucleotide biosynthetic process GO:0009190 63 0.010
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.010
cellular response to hypoxia GO:0071456 51 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
regulation of growth GO:0040008 105 0.010

Trim17 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.145
disease of anatomical entity DOID:7 0 0.145
eye and adnexa disease DOID:1492 0 0.145
nervous system disease DOID:863 0 0.145
eye disease DOID:5614 0 0.120
retinal disease DOID:5679 0 0.050
retinal degeneration DOID:8466 0 0.012