Rattus norvegicus

0 known processes

Slc48a1

solute carrier family 48 (heme transporter), member 1

(Aliases: MGC125237,Hrg1,HRG-1)

Slc48a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic substance catabolic process GO:1901575 316 0.127
regulation of phosphorus metabolic process GO:0051174 349 0.124
regulation of nervous system development GO:0051960 264 0.104
intracellular signal transduction GO:0035556 314 0.101
negative regulation of apoptotic process GO:0043066 181 0.073
oxoacid metabolic process GO:0043436 290 0.070
cation transport GO:0006812 382 0.066
organic acid metabolic process GO:0006082 292 0.066
neuronal action potential GO:0019228 35 0.065
response to bacterium GO:0009617 200 0.064
carboxylic acid metabolic process GO:0019752 289 0.060
programmed cell death GO:0012501 392 0.060
regulation of phosphorylation GO:0042325 248 0.057
regulation of intracellular signal transduction GO:1902531 218 0.057
cell projection organization GO:0030030 302 0.057
negative regulation of cell proliferation GO:0008285 119 0.057
cellular amino acid metabolic process GO:0006520 107 0.056
response to hypoxia GO:0001666 231 0.056
central nervous system development GO:0007417 311 0.055
positive regulation of intracellular signal transduction GO:1902533 138 0.054
nucleoside phosphate metabolic process GO:0006753 283 0.053
nitrogen compound transport GO:0071705 229 0.052
response to toxic substance GO:0009636 133 0.052
neurological system process GO:0050877 219 0.052
positive regulation of cell death GO:0010942 184 0.051
negative regulation of metabolic process GO:0009892 331 0.051
single organism reproductive process GO:0044702 297 0.051
urinary bladder smooth muscle contraction GO:0014832 4 0.051
multicellular organism reproduction GO:0032504 233 0.051
reproductive process GO:0022414 372 0.049
positive regulation of transport GO:0051050 245 0.049
negative regulation of cell communication GO:0010648 158 0.049
chemical homeostasis GO:0048878 292 0.048
amine metabolic process GO:0009308 38 0.048
cellular response to oxygen containing compound GO:1901701 386 0.047
cellular component assembly GO:0022607 360 0.047
regulation of proteasomal protein catabolic process GO:0061136 4 0.047
negative regulation of signaling GO:0023057 157 0.046
neuron projection development GO:0031175 273 0.045
myelination GO:0042552 39 0.045
regulation of multicellular organismal development GO:2000026 376 0.045
negative regulation of cell death GO:0060548 229 0.044
signal release GO:0023061 145 0.043
hormone secretion GO:0046879 115 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.043
regulation of ion transport GO:0043269 245 0.042
regulation of cell proliferation GO:0042127 359 0.042
cellular response to endogenous stimulus GO:0071495 377 0.042
cellular amine metabolic process GO:0044106 38 0.042
regulation of hormone levels GO:0010817 187 0.041
secretion GO:0046903 307 0.041
cellular response to biotic stimulus GO:0071216 59 0.041
positive regulation of peptide secretion GO:0002793 52 0.040
response to decreased oxygen levels GO:0036293 237 0.040
peptide hormone secretion GO:0030072 84 0.040
neuron development GO:0048666 286 0.039
lipid metabolic process GO:0006629 283 0.039
catabolic process GO:0009056 351 0.039
cellular response to stress GO:0033554 269 0.039
synaptic transmission GO:0007268 235 0.039
apoptotic process GO:0006915 381 0.038
transmembrane transport GO:0055085 412 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.038
learning or memory GO:0007611 90 0.038
organophosphate metabolic process GO:0019637 370 0.038
regulation of cellular amine metabolic process GO:0033238 8 0.038
regulation of protein modification process GO:0031399 194 0.038
neuron differentiation GO:0030182 368 0.037
positive regulation of signaling GO:0023056 270 0.037
regulation of membrane potential GO:0042391 110 0.037
positive regulation of hormone secretion GO:0046887 65 0.037
regulation of response to external stimulus GO:0032101 106 0.036
protein phosphorylation GO:0006468 345 0.036
single organism catabolic process GO:0044712 283 0.036
positive regulation of secretion GO:0051047 140 0.036
cell cell signaling GO:0007267 335 0.036
response to nutrient levels GO:0031667 370 0.035
regulation of apoptotic process GO:0042981 335 0.035
macromolecular complex assembly GO:0065003 273 0.035
cellular protein localization GO:0034613 122 0.034
regulation of cell projection organization GO:0031344 175 0.034
response to metal ion GO:0010038 253 0.033
regulation of peptide hormone secretion GO:0090276 80 0.033
positive regulation of peptide hormone secretion GO:0090277 50 0.033
negative regulation of cell development GO:0010721 82 0.033
positive regulation of cellular protein metabolic process GO:0032270 167 0.033
regulation of cellular localization GO:0060341 263 0.033
cellular catabolic process GO:0044248 295 0.032
regulation of neurogenesis GO:0050767 247 0.032
hormone transport GO:0009914 121 0.032
regulation of molecular function GO:0065009 398 0.032
response to oxidative stress GO:0006979 186 0.032
regulation of catalytic activity GO:0050790 304 0.032
cellular ketone metabolic process GO:0042180 51 0.032
response to lipopolysaccharide GO:0032496 191 0.032
regulation of signal transduction GO:0009966 318 0.032
multicellular organismal reproductive process GO:0048609 233 0.031
transmission of nerve impulse GO:0019226 42 0.031
signal transduction by phosphorylation GO:0023014 144 0.031
action potential GO:0001508 54 0.031
reproduction GO:0000003 245 0.030
regulation of neuron differentiation GO:0045664 208 0.030
proteolysis GO:0006508 175 0.030
multi organism reproductive process GO:0044703 262 0.030
response to cgmp GO:0070305 3 0.030
regulation of mapk cascade GO:0043408 116 0.029
regulation of synaptic transmission GO:0050804 141 0.029
response to oxygen levels GO:0070482 265 0.029
cation homeostasis GO:0055080 195 0.028
response to carbohydrate GO:0009743 183 0.028
negative regulation of developmental process GO:0051093 125 0.028
insulin secretion GO:0030073 69 0.028
protein complex subunit organization GO:0071822 302 0.028
cellular homeostasis GO:0019725 252 0.028
regulation of cell differentiation GO:0045595 320 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
positive regulation of cell projection organization GO:0031346 111 0.028
metal ion transport GO:0030001 289 0.027
protein localization GO:0008104 191 0.027
positive regulation of cell communication GO:0010647 271 0.027
regulation of hormone secretion GO:0046883 106 0.027
negative regulation of response to stimulus GO:0048585 155 0.027
cellular response to growth factor stimulus GO:0071363 162 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
cellular response to molecule of bacterial origin GO:0071219 56 0.026
single organism intracellular transport GO:1902582 166 0.026
response to extracellular stimulus GO:0009991 380 0.026
peptide transport GO:0015833 97 0.026
regulation of cellular component organization GO:0051128 368 0.025
regulation of protein metabolic process GO:0051246 289 0.025
negative regulation of phosphorus metabolic process GO:0010563 80 0.025
response to growth factor GO:0070848 189 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
tissue development GO:0009888 252 0.025
cellular component biogenesis GO:0044085 368 0.025
regulation of neural precursor cell proliferation GO:2000177 16 0.025
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.025
ion homeostasis GO:0050801 212 0.024
regulation of cell maturation GO:1903429 3 0.024
muscle structure development GO:0061061 87 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
regulation of cellular catabolic process GO:0031329 101 0.024
peptidyl amino acid modification GO:0018193 126 0.024
regulation of response to stress GO:0080134 126 0.024
positive regulation of cellular component organization GO:0051130 200 0.024
metal ion homeostasis GO:0055065 186 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
chromosome segregation GO:0007059 2 0.024
divalent inorganic cation homeostasis GO:0072507 165 0.023
cellular chemical homeostasis GO:0055082 247 0.023
response to other organism GO:0051707 220 0.023
inorganic cation transmembrane transport GO:0098662 202 0.023
response to external biotic stimulus GO:0043207 221 0.023
negative regulation of neurogenesis GO:0050768 78 0.023
reactive oxygen species metabolic process GO:0072593 37 0.023
urinary tract smooth muscle contraction GO:0014848 4 0.023
cellular metal ion homeostasis GO:0006875 172 0.022
regulation of peptide secretion GO:0002791 82 0.022
regulation of peptide transport GO:0090087 87 0.022
circulatory system process GO:0003013 183 0.022
regulation of secretion by cell GO:1903530 208 0.022
secretion by cell GO:0032940 248 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
negative regulation of cellular protein metabolic process GO:0032269 106 0.022
aging GO:0007568 241 0.022
positive regulation of organic acid transport GO:0032892 22 0.021
nucleic acid templated transcription GO:0097659 379 0.021
negative regulation of nervous system development GO:0051961 79 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
regulation of cell development GO:0060284 263 0.021
mapk cascade GO:0000165 140 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
cation transmembrane transport GO:0098655 263 0.021
cellular macromolecule localization GO:0070727 122 0.020
divalent metal ion transport GO:0070838 132 0.020
negative regulation of phosphate metabolic process GO:0045936 80 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
brain development GO:0007420 247 0.020
cellular cation homeostasis GO:0030003 180 0.020
regulation of programmed cell death GO:0043067 341 0.020
negative regulation of reactive oxygen species metabolic process GO:2000378 7 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
positive regulation of insulin secretion GO:0032024 36 0.020
heart morphogenesis GO:0003007 3 0.020
intracellular transport GO:0046907 185 0.020
glucose homeostasis GO:0042593 75 0.020
regulation of secretion GO:0051046 224 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
regulation of anatomical structure size GO:0090066 135 0.019
homeostatic process GO:0042592 331 0.019
blood circulation GO:0008015 183 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
response to molecule of bacterial origin GO:0002237 194 0.019
response to biotic stimulus GO:0009607 226 0.019
sexual reproduction GO:0019953 148 0.019
organic anion transport GO:0015711 132 0.019
programmed necrotic cell death GO:0097300 2 0.019
response to ammonium ion GO:0060359 71 0.018
positive regulation of proteasomal protein catabolic process GO:1901800 3 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
cognition GO:0050890 92 0.018
negative regulation of mapk cascade GO:0043409 20 0.018
defense response GO:0006952 194 0.018
cell cycle process GO:0022402 57 0.018
regulation of transferase activity GO:0051338 123 0.018
regulation of neuron projection development GO:0010975 161 0.017
acid secretion GO:0046717 48 0.017
single organism carbohydrate metabolic process GO:0044723 118 0.017
anion transport GO:0006820 178 0.017
cell cycle GO:0007049 101 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
response to lead ion GO:0010288 33 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
macromolecule localization GO:0033036 252 0.017
response to reactive oxygen species GO:0000302 120 0.017
response to monosaccharide GO:0034284 159 0.017
negative regulation of protein metabolic process GO:0051248 114 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
calcium ion transport GO:0006816 131 0.016
regulation of homeostatic process GO:0032844 101 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
membrane organization GO:0061024 94 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
gamete generation GO:0007276 124 0.016
divalent inorganic cation transport GO:0072511 134 0.016
necroptotic process GO:0070266 2 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
head development GO:0060322 247 0.016
neuron neuron synaptic transmission GO:0007270 60 0.016
negative regulation of cell differentiation GO:0045596 99 0.016
regulation of reactive oxygen species metabolic process GO:2000377 26 0.016
glial cell differentiation GO:0010001 65 0.016
response to cytokine GO:0034097 215 0.016
regulation of chromosome segregation GO:0051983 1 0.016
organelle organization GO:0006996 266 0.016
cellular response to external stimulus GO:0071496 118 0.015
protein complex assembly GO:0006461 263 0.015
gliogenesis GO:0042063 93 0.015
smooth muscle contraction GO:0006939 37 0.015
response to alkaloid GO:0043279 132 0.015
single organism membrane organization GO:0044802 74 0.015
negative regulation of intracellular signal transduction GO:1902532 38 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
positive regulation of cell development GO:0010720 176 0.015
regulation of defense response GO:0031347 68 0.015
nucleotide metabolic process GO:0009117 279 0.015
monocarboxylic acid transport GO:0015718 52 0.015
amide transport GO:0042886 105 0.015
cellular response to hypoxia GO:0071456 51 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
response to starvation GO:0042594 59 0.015
muscle organ development GO:0007517 50 0.014
maintenance of location GO:0051235 17 0.014
cell morphogenesis GO:0000902 142 0.014
positive regulation of nervous system development GO:0051962 178 0.014
cell type specific apoptotic process GO:0097285 134 0.014
sulfur compound metabolic process GO:0006790 70 0.014
axon ensheathment GO:0008366 40 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
positive regulation of kinase activity GO:0033674 77 0.014
cellular component morphogenesis GO:0032989 155 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
cellular response to extracellular stimulus GO:0031668 73 0.013
macromolecule catabolic process GO:0009057 58 0.013
negative regulation of molecular function GO:0044092 133 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.013
negative regulation of transport GO:0051051 136 0.013
carbohydrate homeostasis GO:0033500 75 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
positive regulation of catabolic process GO:0009896 78 0.013
response to herbicide GO:0009635 16 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
cellular response to cgmp GO:0071321 2 0.013
regulation of blood vessel size GO:0050880 89 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
neural precursor cell proliferation GO:0061351 23 0.013
negative regulation of response to biotic stimulus GO:0002832 4 0.013
cytoskeleton organization GO:0007010 111 0.013
positive regulation of transferase activity GO:0051347 81 0.013
protein complex biogenesis GO:0070271 263 0.013
negative regulation of muscle organ development GO:0048635 8 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
cellular protein catabolic process GO:0044257 19 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
positive regulation of ion transport GO:0043270 94 0.012
regulation of erk1 and erk2 cascade GO:0070372 41 0.012
cellular response to oxidative stress GO:0034599 76 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
protein transport GO:0015031 132 0.012
regulation of kinase activity GO:0043549 117 0.012
single organism biosynthetic process GO:0044711 342 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
positive regulation of protein modification process GO:0031401 142 0.012
sphingolipid biosynthetic process GO:0030148 4 0.012
autophagic cell death GO:0048102 4 0.012
negative regulation of innate immune response GO:0045824 4 0.012
cell motility GO:0048870 202 0.012
regulation of tube size GO:0035150 89 0.012
regulation of fat cell differentiation GO:0045598 3 0.012
neuron projection morphogenesis GO:0048812 122 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
positive regulation of biosynthetic process GO:0009891 319 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
regulation of anion transport GO:0044070 43 0.011
rna metabolic process GO:0016070 406 0.011
cellular response to reactive oxygen species GO:0034614 55 0.011
negative regulation of gene expression GO:0010629 199 0.011
meiotic cell cycle process GO:1903046 3 0.011
macromolecular complex subunit organization GO:0043933 339 0.011
heterocycle catabolic process GO:0046700 167 0.011
purine containing compound metabolic process GO:0072521 253 0.011
muscle tissue development GO:0060537 58 0.011
calcium ion homeostasis GO:0055074 162 0.011
negative regulation of protein phosphorylation GO:0001933 44 0.011
protein oligomerization GO:0051259 191 0.011
response to estradiol GO:0032355 164 0.011
response to ethanol GO:0045471 162 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
amino acid transport GO:0006865 70 0.011
hexose transport GO:0008645 29 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
glycerolipid metabolic process GO:0046486 67 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
positive regulation of response to stimulus GO:0048584 285 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
regulation of protein kinase activity GO:0045859 105 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
response to estrogen GO:0043627 232 0.010
response to ketone GO:1901654 182 0.010
ras protein signal transduction GO:0007265 29 0.010
striated muscle tissue development GO:0014706 58 0.010
regulation of rna biosynthetic process GO:2001141 381 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
regulation of immune system process GO:0002682 123 0.010
cellular component movement GO:0006928 248 0.010
vascular process in circulatory system GO:0003018 96 0.010
organ formation GO:0048645 3 0.010
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 3 0.010
vasoconstriction GO:0042310 54 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
microtubule based process GO:0007017 36 0.010

Slc48a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
nervous system disease DOID:863 0 0.057
musculoskeletal system disease DOID:17 0 0.025
central nervous system disease DOID:331 0 0.023
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018
connective tissue disease DOID:65 0 0.012
neuromuscular disease DOID:440 0 0.010
charcot marie tooth disease type 2 DOID:0050539 0 0.010
charcot marie tooth disease DOID:10595 0 0.010
neuropathy DOID:870 0 0.010