Rattus norvegicus

4 known processes

Cox8b

cytochrome c oxidase, subunit VIIIb

(Aliases: COXVIII-H,CCO8A,Cox8h)

Cox8b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.391
muscle system process GO:0003012 115 0.229
carboxylic acid metabolic process GO:0019752 289 0.225
organic acid metabolic process GO:0006082 292 0.158
organic anion transport GO:0015711 132 0.151
muscle contraction GO:0006936 88 0.134
response to inorganic substance GO:0010035 377 0.129
homeostatic process GO:0042592 331 0.128
cardiac muscle tissue morphogenesis GO:0055008 1 0.123
regulation of ion transport GO:0043269 245 0.100
cardiac muscle contraction GO:0060048 27 0.095
single organism carbohydrate catabolic process GO:0044724 40 0.093
response to nutrient levels GO:0031667 370 0.090
nucleobase containing small molecule metabolic process GO:0055086 316 0.089
cation transport GO:0006812 382 0.088
twitch skeletal muscle contraction GO:0014721 3 0.087
cellular chemical homeostasis GO:0055082 247 0.083
response to extracellular stimulus GO:0009991 380 0.082
single organism reproductive process GO:0044702 297 0.079
reproductive process GO:0022414 372 0.078
single organism biosynthetic process GO:0044711 342 0.077
purine containing compound metabolic process GO:0072521 253 0.075
multicellular organism reproduction GO:0032504 233 0.073
gluconeogenesis GO:0006094 15 0.071
cellular response to stress GO:0033554 269 0.071
single organism catabolic process GO:0044712 283 0.071
cellular ion homeostasis GO:0006873 184 0.068
carbohydrate derivative metabolic process GO:1901135 346 0.068
atp metabolic process GO:0046034 72 0.067
blood circulation GO:0008015 183 0.067
cellular component biogenesis GO:0044085 368 0.066
protein complex biogenesis GO:0070271 263 0.063
cardiac ventricle development GO:0003231 1 0.063
macromolecular complex assembly GO:0065003 273 0.061
striated muscle contraction GO:0006941 44 0.061
organic substance catabolic process GO:1901575 316 0.060
nucleotide metabolic process GO:0009117 279 0.059
catabolic process GO:0009056 351 0.057
muscle organ morphogenesis GO:0048644 1 0.057
regulation of system process GO:0044057 208 0.056
reproduction GO:0000003 245 0.056
circulatory system development GO:0072359 134 0.056
cellular component assembly GO:0022607 360 0.055
cell projection organization GO:0030030 302 0.054
cell cell signaling GO:0007267 335 0.053
cellular amino acid metabolic process GO:0006520 107 0.053
multicellular organismal reproductive process GO:0048609 233 0.052
organelle organization GO:0006996 266 0.051
chemical homeostasis GO:0048878 292 0.051
cellular homeostasis GO:0019725 252 0.050
organophosphate metabolic process GO:0019637 370 0.050
developmental process involved in reproduction GO:0003006 159 0.049
cellular response to oxygen containing compound GO:1901701 386 0.049
oxidation reduction process GO:0055114 304 0.048
response to oxidative stress GO:0006979 186 0.048
protein complex assembly GO:0006461 263 0.046
slow twitch skeletal muscle fiber contraction GO:0031444 2 0.046
response to metal ion GO:0010038 253 0.045
lipid metabolic process GO:0006629 283 0.045
defense response GO:0006952 194 0.045
small molecule biosynthetic process GO:0044283 124 0.043
cardiac chamber development GO:0003205 1 0.043
multi organism reproductive process GO:0044703 262 0.043
secretion GO:0046903 307 0.042
regulation of cellular component organization GO:0051128 368 0.041
cellular catabolic process GO:0044248 295 0.041
nucleoside monophosphate metabolic process GO:0009123 93 0.041
cellular divalent inorganic cation homeostasis GO:0072503 162 0.041
organophosphate biosynthetic process GO:0090407 143 0.039
cellular amine metabolic process GO:0044106 38 0.039
lipid transport GO:0006869 61 0.039
purine nucleoside monophosphate metabolic process GO:0009126 84 0.039
neuron development GO:0048666 286 0.038
single organism organelle organization GO:1902589 180 0.038
response to starvation GO:0042594 59 0.038
regulation of membrane potential GO:0042391 110 0.038
regulation of cellular ketone metabolic process GO:0010565 27 0.037
organic acid biosynthetic process GO:0016053 83 0.037
amine metabolic process GO:0009308 38 0.037
regulation of cellular localization GO:0060341 263 0.037
circulatory system process GO:0003013 183 0.036
purine ribonucleotide metabolic process GO:0009150 227 0.036
cellular amino acid biosynthetic process GO:0008652 32 0.036
heart contraction GO:0060047 57 0.036
tissue development GO:0009888 252 0.036
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.035
long chain fatty acid transport GO:0015909 14 0.035
heart development GO:0007507 72 0.035
central nervous system development GO:0007417 311 0.034
protein complex subunit organization GO:0071822 302 0.034
response to heat GO:0009408 60 0.034
monocarboxylic acid metabolic process GO:0032787 152 0.034
cold acclimation GO:0009631 1 0.033
negative regulation of metabolic process GO:0009892 331 0.033
anion transport GO:0006820 178 0.033
carbohydrate catabolic process GO:0016052 40 0.033
organonitrogen compound biosynthetic process GO:1901566 167 0.033
regulation of rna metabolic process GO:0051252 391 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
head development GO:0060322 247 0.032
response to estradiol GO:0032355 164 0.032
divalent inorganic cation transport GO:0072511 134 0.032
glycosyl compound metabolic process GO:1901657 182 0.032
response to decreased oxygen levels GO:0036293 237 0.032
dicarboxylic acid metabolic process GO:0043648 42 0.032
macromolecule localization GO:0033036 252 0.032
cellular protein complex assembly GO:0043623 44 0.031
diaphragm contraction GO:0002086 2 0.031
cation homeostasis GO:0055080 195 0.031
neuron differentiation GO:0030182 368 0.031
response to monosaccharide GO:0034284 159 0.031
calcium ion homeostasis GO:0055074 162 0.030
lipid localization GO:0010876 62 0.030
immune system process GO:0002376 204 0.029
ion transmembrane transport GO:0034220 365 0.029
response to oxygen levels GO:0070482 265 0.029
response to ethanol GO:0045471 162 0.029
nucleoside phosphate catabolic process GO:1901292 140 0.029
actin mediated cell contraction GO:0070252 12 0.029
anatomical structure formation involved in morphogenesis GO:0048646 83 0.029
cellular calcium ion homeostasis GO:0006874 160 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.028
inorganic cation transmembrane transport GO:0098662 202 0.028
erythrocyte differentiation GO:0030218 1 0.028
ribonucleotide catabolic process GO:0009261 136 0.028
negative regulation of cardiac muscle tissue development GO:0055026 3 0.028
pyruvate metabolic process GO:0006090 27 0.028
monovalent inorganic cation transport GO:0015672 172 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
regulation of rna biosynthetic process GO:2001141 381 0.027
ion homeostasis GO:0050801 212 0.027
muscle filament sliding GO:0030049 2 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
ribonucleoside monophosphate metabolic process GO:0009161 88 0.026
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.026
cellular ketone metabolic process GO:0042180 51 0.026
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.026
carboxylic acid transport GO:0046942 115 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
response to purine containing compound GO:0014074 126 0.025
fatty acid metabolic process GO:0006631 99 0.025
regulation of organelle organization GO:0033043 80 0.025
metal ion transport GO:0030001 289 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.025
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.025
purine containing compound catabolic process GO:0072523 138 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
purine nucleotide metabolic process GO:0006163 229 0.024
signal release GO:0023061 145 0.024
heart morphogenesis GO:0003007 3 0.024
muscle structure development GO:0061061 87 0.024
myosin filament assembly GO:0031034 1 0.024
purine nucleoside metabolic process GO:0042278 169 0.024
heart process GO:0003015 57 0.024
carbohydrate derivative catabolic process GO:1901136 147 0.024
cardiovascular system development GO:0072358 134 0.024
regulation of muscle filament sliding GO:0032971 1 0.023
organic hydroxy compound metabolic process GO:1901615 115 0.023
response to glucose GO:0009749 136 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
negative regulation of transport GO:0051051 136 0.023
rna metabolic process GO:0016070 406 0.023
cardiac myofibril assembly GO:0055003 1 0.023
response to acid chemical GO:0001101 222 0.023
regulation of secretion GO:0051046 224 0.023
ventricular cardiac muscle cell action potential GO:0086005 2 0.023
response to carbohydrate GO:0009743 183 0.023
cation transmembrane transport GO:0098655 263 0.023
regulation of multicellular organismal development GO:2000026 376 0.022
multi multicellular organism process GO:0044706 138 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
response to temperature stimulus GO:0009266 94 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
positive regulation of long term synaptic potentiation GO:1900273 4 0.022
regulation of cytoskeleton organization GO:0051493 49 0.021
protein oligomerization GO:0051259 191 0.021
positive regulation of ion transport GO:0043270 94 0.021
multicellular organismal movement GO:0050879 17 0.021
nucleoside monophosphate catabolic process GO:0009125 56 0.021
cellular component movement GO:0006928 248 0.021
regulation of homeostatic process GO:0032844 101 0.021
ribonucleotide metabolic process GO:0009259 231 0.020
metal ion homeostasis GO:0055065 186 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
divalent inorganic cation homeostasis GO:0072507 165 0.020
regulation of peptide hormone secretion GO:0090276 80 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.020
voluntary skeletal muscle contraction GO:0003010 3 0.020
response to reactive oxygen species GO:0000302 120 0.020
potassium ion transmembrane transport GO:0071805 71 0.020
muscle tissue morphogenesis GO:0060415 1 0.020
sexual reproduction GO:0019953 148 0.020
response to nutrient GO:0007584 248 0.020
secretion by cell GO:0032940 248 0.019
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 1 0.019
nucleoside metabolic process GO:0009116 179 0.019
positive regulation of lipid catabolic process GO:0050996 4 0.019
aging GO:0007568 241 0.019
positive regulation of transport GO:0051050 245 0.019
cardiocyte differentiation GO:0035051 22 0.019
cellular macromolecular complex assembly GO:0034622 58 0.019
skeletal muscle contraction GO:0003009 17 0.019
regulation of cell differentiation GO:0045595 320 0.019
carboxylic acid biosynthetic process GO:0046394 83 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
actin myosin filament sliding GO:0033275 2 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
gamete generation GO:0007276 124 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
vitamin a metabolic process GO:0006776 2 0.018
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.018
regulation of ion transmembrane transport GO:0034765 121 0.018
nitrogen compound transport GO:0071705 229 0.018
intracellular signal transduction GO:0035556 314 0.018
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
ribonucleoside catabolic process GO:0042454 126 0.018
sodium ion transport GO:0006814 82 0.018
hormone transport GO:0009914 121 0.018
fatty acid transport GO:0015908 25 0.018
peptide secretion GO:0002790 86 0.018
cellular component morphogenesis GO:0032989 155 0.018
cellular modified amino acid biosynthetic process GO:0042398 18 0.018
negative regulation of heart growth GO:0061117 3 0.018
purine ribonucleotide catabolic process GO:0009154 136 0.017
regulation of peptide secretion GO:0002791 82 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
nucleoside catabolic process GO:0009164 126 0.017
regulation of hormone secretion GO:0046883 106 0.017
locomotion GO:0040011 237 0.017
response to hypoxia GO:0001666 231 0.017
regulation of hormone levels GO:0010817 187 0.017
response to wounding GO:0009611 254 0.017
response to peptide hormone GO:0043434 278 0.017
immune system development GO:0002520 41 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
generation of precursor metabolites and energy GO:0006091 62 0.017
regulation of cellular component biogenesis GO:0044087 86 0.017
cellular cation homeostasis GO:0030003 180 0.017
actin filament based process GO:0030029 86 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
negative regulation of cell death GO:0060548 229 0.016
aromatic compound catabolic process GO:0019439 168 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
rna biosynthetic process GO:0032774 380 0.016
purine nucleoside monophosphate catabolic process GO:0009128 55 0.016
hemopoiesis GO:0030097 34 0.016
peptide transport GO:0015833 97 0.016
gonad development GO:0008406 104 0.016
potassium ion transport GO:0006813 97 0.016
fatty acid oxidation GO:0019395 29 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
reproductive system development GO:0061458 128 0.016
striated muscle tissue development GO:0014706 58 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
glucose homeostasis GO:0042593 75 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
neuron projection development GO:0031175 273 0.015
male gamete generation GO:0048232 99 0.015
response to peptide GO:1901652 292 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
regulation of tube size GO:0035150 89 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
negative regulation of molecular function GO:0044092 133 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
ventricular cardiac muscle cell differentiation GO:0055012 2 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
nucleoside triphosphate catabolic process GO:0009143 123 0.015
monocarboxylic acid transport GO:0015718 52 0.015
regulation of programmed cell death GO:0043067 341 0.014
liver development GO:0001889 90 0.014
heterocycle catabolic process GO:0046700 167 0.014
spermatogenesis GO:0007283 99 0.014
regulation of secretion by cell GO:1903530 208 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.014
regulation of neuron differentiation GO:0045664 208 0.014
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.014
hexose biosynthetic process GO:0019319 15 0.014
muscle cell differentiation GO:0042692 52 0.014
regulation of ion transmembrane transporter activity GO:0032412 48 0.014
response to ionizing radiation GO:0010212 59 0.014
lipid storage GO:0019915 1 0.014
hexose metabolic process GO:0019318 58 0.014
regulation of protein complex assembly GO:0043254 33 0.014
hematopoietic or lymphoid organ development GO:0048534 36 0.014
regulation of cell growth GO:0001558 85 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
cellular macromolecule localization GO:0070727 122 0.014
regulation of transcription dna templated GO:0006355 374 0.014
response to glucocorticoid GO:0051384 223 0.014
nucleic acid templated transcription GO:0097659 379 0.013
reproductive structure development GO:0048608 128 0.013
amide transport GO:0042886 105 0.013
regulation of cell proliferation GO:0042127 359 0.013
regulation of muscle system process GO:0090257 79 0.013
regeneration GO:0031099 163 0.013
regulation of molecular function GO:0065009 398 0.013
cell morphogenesis GO:0000902 142 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
apoptotic process GO:0006915 381 0.013
actin filament based movement GO:0030048 16 0.013
transmembrane transport GO:0055085 412 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
action potential GO:0001508 54 0.013
positive regulation of signal transduction GO:0009967 175 0.013
organic acid transport GO:0015849 116 0.013
sensory organ development GO:0007423 74 0.013
syncytium formation GO:0006949 4 0.013
muscle tissue development GO:0060537 58 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
regulation of cell projection organization GO:0031344 175 0.013
negative regulation of organ growth GO:0046621 3 0.013
cellular potassium ion transport GO:0071804 72 0.013
regulation of metal ion transport GO:0010959 118 0.012
sequestering of calcium ion GO:0051208 8 0.012
single organism intracellular transport GO:1902582 166 0.012
positive regulation of signaling GO:0023056 270 0.012
regulation of muscle contraction GO:0006937 53 0.012
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.012
behavior GO:0007610 205 0.012
regulation of ion homeostasis GO:2000021 63 0.012
regulation of apoptotic process GO:0042981 335 0.012
adult locomotory behavior GO:0008344 4 0.012
carbohydrate homeostasis GO:0033500 75 0.012
mitotic sister chromatid separation GO:0051306 1 0.012
response to bacterium GO:0009617 200 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
regulation of response to stress GO:0080134 126 0.012
negative regulation of gene expression GO:0010629 199 0.012
glucose metabolic process GO:0006006 52 0.012
telencephalon development GO:0021537 62 0.012
divalent metal ion transport GO:0070838 132 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
regulation of peptide transport GO:0090087 87 0.012
response to insulin GO:0032868 133 0.012
programmed cell death GO:0012501 392 0.012
axon development GO:0061564 96 0.012
erythrocyte homeostasis GO:0034101 2 0.012
monosaccharide metabolic process GO:0005996 61 0.012
regulation of neurogenesis GO:0050767 247 0.012
regulation of blood vessel size GO:0050880 89 0.012
brain development GO:0007420 247 0.012
actin cytoskeleton organization GO:0030036 73 0.012
inflammatory response GO:0006954 150 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
hormone secretion GO:0046879 115 0.011
negative regulation of protein import into nucleus translocation GO:0033159 1 0.011
intracellular transport GO:0046907 185 0.011
phospholipid metabolic process GO:0006644 61 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
single organism behavior GO:0044708 130 0.011
cytoskeleton organization GO:0007010 111 0.011
regulation of cell development GO:0060284 263 0.011
cellular response to nutrient levels GO:0031669 60 0.011
rna localization GO:0006403 4 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
regulation of neuron projection development GO:0010975 161 0.011
regulation of catabolic process GO:0009894 113 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
carbohydrate metabolic process GO:0005975 130 0.011
carbohydrate biosynthetic process GO:0016051 42 0.011
alcohol metabolic process GO:0006066 77 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
cellular protein localization GO:0034613 122 0.011
organ morphogenesis GO:0009887 75 0.011
cellular response to carbohydrate stimulus GO:0071322 72 0.011
regulation of fibrinolysis GO:0051917 2 0.011
regulation of blood pressure GO:0008217 83 0.011
axis specification GO:0009798 4 0.011
embryonic pattern specification GO:0009880 1 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
protein polymerization GO:0051258 22 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
sequestering of metal ion GO:0051238 9 0.010
maintenance of location GO:0051235 17 0.010
response to hexose GO:0009746 144 0.010
negative regulation of secretion by cell GO:1903531 72 0.010
sex differentiation GO:0007548 113 0.010
placenta development GO:0001890 22 0.010
actomyosin structure organization GO:0031032 22 0.010
respiratory gaseous exchange GO:0007585 4 0.010
organophosphate catabolic process GO:0046434 148 0.010
cellular component assembly involved in morphogenesis GO:0010927 17 0.010
neuron projection morphogenesis GO:0048812 122 0.010
myeloid cell differentiation GO:0030099 22 0.010
cellular modified amino acid metabolic process GO:0006575 61 0.010
single organism membrane organization GO:0044802 74 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
hepaticobiliary system development GO:0061008 90 0.010
cell cycle checkpoint GO:0000075 2 0.010
regulation of nervous system development GO:0051960 264 0.010
peptide hormone secretion GO:0030072 84 0.010
embryonic placenta development GO:0001892 1 0.010

Cox8b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.738
muscular disease DOID:0080000 0 0.738
heart disease DOID:114 0 0.738
cardiomyopathy DOID:0050700 0 0.738
disease of anatomical entity DOID:7 0 0.738
intrinsic cardiomyopathy DOID:0060036 0 0.738
cardiovascular system disease DOID:1287 0 0.738
musculoskeletal system disease DOID:17 0 0.738
muscle tissue disease DOID:66 0 0.738
hypertrophic cardiomyopathy DOID:11984 0 0.089
dilated cardiomyopathy DOID:12930 0 0.056
disease of metabolism DOID:0014667 0 0.041
carbohydrate metabolic disorder DOID:2978 0 0.023
inherited metabolic disorder DOID:655 0 0.023
congenital heart disease DOID:1682 0 0.017
heart septal defect DOID:1681 0 0.017
nutrition disease DOID:374 0 0.015
acquired metabolic disease DOID:0060158 0 0.015
nervous system disease DOID:863 0 0.014
obesity DOID:9970 0 0.013
overnutrition DOID:654 0 0.013
central nervous system disease DOID:331 0 0.010