Rattus norvegicus

0 known processes

LOC100362108

poly (ADP-ribose) polymerase family, member 10

LOC100362108 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
epithelial cell differentiation involved in kidney development GO:0035850 3 0.635
positive regulation of skeletal muscle cell proliferation GO:0014858 2 0.352
regulation of metanephros development GO:0072215 4 0.326
cell proliferation involved in metanephros development GO:0072203 2 0.292
negative regulation of metanephros development GO:0072217 2 0.211
cell differentiation involved in kidney development GO:0061005 4 0.195
regulation of satellite cell proliferation GO:0014842 1 0.178
mesenchymal cell differentiation involved in renal system development GO:2001012 1 0.172
nucleotide metabolic process GO:0009117 279 0.169
jak stat cascade GO:0007259 26 0.152
transcription dna templated GO:0006351 377 0.139
Human
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.136
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003340 2 0.134
skeletal muscle satellite cell proliferation GO:0014841 1 0.133
intracellular signal transduction GO:0035556 314 0.126
mesenchymal cell proliferation GO:0010463 4 0.121
metanephric mesenchymal cell differentiation GO:0072162 1 0.120
regulation of phosphate metabolic process GO:0019220 349 0.119
positive regulation of rna biosynthetic process GO:1902680 197 0.118
regulation of mesenchymal cell proliferation GO:0010464 4 0.118
positive regulation of growth factor dependent skeletal muscle satellite cell proliferation GO:1902728 1 0.113
nucleoside phosphate metabolic process GO:0006753 283 0.109
cellular response to stress GO:0033554 269 0.104
regulation of hydrogen peroxide biosynthetic process GO:0010728 2 0.104
response to external biotic stimulus GO:0043207 221 0.098
nucleic acid templated transcription GO:0097659 379 0.095
Human
organophosphate metabolic process GO:0019637 370 0.088
response to lipopolysaccharide GO:0032496 191 0.087
mesenchymal to epithelial transition GO:0060231 3 0.086
positive regulation of cell communication GO:0010647 271 0.086
metanephric renal vesicle morphogenesis GO:0072283 3 0.080
regulation of transcription dna templated GO:0006355 374 0.080
Human
positive regulation of gene expression GO:0010628 244 0.079
regulation of molecular function GO:0065009 398 0.078
Human
organelle organization GO:0006996 266 0.078
Human
nucleobase containing small molecule metabolic process GO:0055086 316 0.075
metanephric nephron tubule epithelial cell differentiation GO:0072257 1 0.074
cellular component assembly GO:0022607 360 0.073
Human
response to other organism GO:0051707 220 0.072
purine containing compound metabolic process GO:0072521 253 0.071
response to bacterium GO:0009617 200 0.067
mesenchymal cell differentiation involved in kidney development GO:0072161 1 0.066
cellular response to cytokine stimulus GO:0071345 127 0.065
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.064
purine nucleoside triphosphate metabolic process GO:0009144 141 0.064
ribonucleotide metabolic process GO:0009259 231 0.063
cellular response to oxygen containing compound GO:1901701 386 0.058
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.057
negative regulation of nephron tubule epithelial cell differentiation GO:0072183 1 0.057
nephron tubule epithelial cell differentiation GO:0072160 1 0.057
positive regulation of transcription dna templated GO:0045893 197 0.057
purine ribonucleotide metabolic process GO:0009150 227 0.057
atp metabolic process GO:0046034 72 0.057
ribonucleoside metabolic process GO:0009119 174 0.056
cellular response to nitrogen compound GO:1901699 210 0.056
negative regulation of metabolic process GO:0009892 331 0.055
Human
purine nucleotide metabolic process GO:0006163 229 0.054
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.054
regulation of nucleic acid templated transcription GO:1903506 380 0.053
Human
regulation of intracellular signal transduction GO:1902531 218 0.053
nucleoside metabolic process GO:0009116 179 0.052
cellular response to hormone stimulus GO:0032870 247 0.051
regulation of rna biosynthetic process GO:2001141 381 0.049
Human
response to biotic stimulus GO:0009607 226 0.049
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.048
negative regulation of hydrogen peroxide metabolic process GO:0010727 2 0.048
positive regulation of signal transduction GO:0009967 175 0.047
glycosyl compound metabolic process GO:1901657 182 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.046
positive regulation of satellite cell proliferation GO:1902724 1 0.046
macromolecular complex subunit organization GO:0043933 339 0.046
Human
positive regulation of phosphate metabolic process GO:0045937 262 0.046
cellular response to peptide hormone stimulus GO:0071375 120 0.045
secretion by tissue GO:0032941 37 0.043
cellular amino acid metabolic process GO:0006520 107 0.043
oxoacid metabolic process GO:0043436 290 0.043
nucleoside monophosphate metabolic process GO:0009123 93 0.043
regulation of rna metabolic process GO:0051252 391 0.043
Human
purine ribonucleotide biosynthetic process GO:0009152 81 0.042
liver development GO:0001889 90 0.042
carbohydrate derivative biosynthetic process GO:1901137 124 0.041
Human
positive regulation of rna metabolic process GO:0051254 203 0.041
regulation of nephron tubule epithelial cell differentiation GO:0072182 1 0.041
cellular amine metabolic process GO:0044106 38 0.041
response to peptide hormone GO:0043434 278 0.041
cytokine mediated signaling pathway GO:0019221 43 0.041
organic substance catabolic process GO:1901575 316 0.041
cell differentiation involved in metanephros development GO:0072202 1 0.040
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.040
protein phosphorylation GO:0006468 345 0.040
positive regulation of cellular biosynthetic process GO:0031328 295 0.040
defense response GO:0006952 194 0.040
purine nucleoside metabolic process GO:0042278 169 0.040
purine containing compound biosynthetic process GO:0072522 85 0.040
positive regulation of nucleotide metabolic process GO:0045981 91 0.039
regulation of purine nucleotide metabolic process GO:1900542 115 0.039
regulation of multicellular organismal development GO:2000026 376 0.039
metanephros morphogenesis GO:0003338 6 0.038
negative regulation of macromolecule metabolic process GO:0010605 260 0.038
Human
ribonucleoside triphosphate metabolic process GO:0009199 141 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.038
Human
innate immune response activating signal transduction GO:0002758 9 0.038
regulation of catalytic activity GO:0050790 304 0.038
positive regulation of cell proliferation GO:0008284 249 0.037
regulation of cellular component organization GO:0051128 368 0.037
Human
circulatory system process GO:0003013 183 0.037
negative regulation of reactive oxygen species metabolic process GO:2000378 7 0.036
apoptotic process GO:0006915 381 0.036
rna biosynthetic process GO:0032774 380 0.036
Human
response to molecule of bacterial origin GO:0002237 194 0.036
blood circulation GO:0008015 183 0.036
response to purine containing compound GO:0014074 126 0.036
epithelial cell differentiation GO:0030855 71 0.036
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003339 2 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.035
ribonucleoside monophosphate metabolic process GO:0009161 88 0.035
cellular ketone metabolic process GO:0042180 51 0.035
purine nucleoside monophosphate metabolic process GO:0009126 84 0.035
regulation of epithelial cell differentiation GO:0030856 12 0.035
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.035
reactive oxygen species biosynthetic process GO:1903409 8 0.034
metanephric mesenchymal cell proliferation involved in metanephros development GO:0072136 1 0.034
nucleoside phosphate biosynthetic process GO:1901293 102 0.034
regulation of cell differentiation GO:0045595 320 0.034
negative regulation of cell development GO:0010721 82 0.034
cation transport GO:0006812 382 0.033
regulation of cell proliferation GO:0042127 359 0.033
Human
response to cytokine GO:0034097 215 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
nucleoside triphosphate metabolic process GO:0009141 144 0.032
negative regulation of kidney development GO:0090185 2 0.032
response to molecule of fungal origin GO:0002238 3 0.032
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
rna metabolic process GO:0016070 406 0.031
Human
metanephric epithelium development GO:0072207 4 0.031
single organism biosynthetic process GO:0044711 342 0.031
macromolecular complex assembly GO:0065003 273 0.031
Human
negative regulation of biosynthetic process GO:0009890 168 0.031
cellular catabolic process GO:0044248 295 0.030
reproductive process GO:0022414 372 0.030
regulation of signal transduction GO:0009966 318 0.030
cellular response to peptide GO:1901653 133 0.030
positive regulation of cell death GO:0010942 184 0.030
organophosphate biosynthetic process GO:0090407 143 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
Human
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
regulation of skeletal muscle cell proliferation GO:0014857 2 0.029
establishment of protein localization GO:0045184 141 0.029
Human
secretion GO:0046903 307 0.029
regulation of reactive oxygen species metabolic process GO:2000377 26 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
aging GO:0007568 241 0.028
cell morphogenesis involved in differentiation GO:0000904 119 0.028
regulation of nucleotide metabolic process GO:0006140 117 0.028
negative regulation of developmental process GO:0051093 125 0.027
catabolic process GO:0009056 351 0.027
ribonucleotide biosynthetic process GO:0009260 85 0.027
positive regulation of protein transport GO:0051222 41 0.027
innate immune response GO:0045087 35 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
nucleotide biosynthetic process GO:0009165 98 0.026
regulation of epithelial cell differentiation involved in kidney development GO:2000696 1 0.026
amide transport GO:0042886 105 0.026
reactive oxygen species metabolic process GO:0072593 37 0.026
response to nutrient levels GO:0031667 370 0.026
purine nucleoside biosynthetic process GO:0042451 21 0.026
kidney mesenchyme development GO:0072074 2 0.026
protein complex biogenesis GO:0070271 263 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.025
inflammatory response GO:0006954 150 0.025
regulation of cell morphogenesis GO:0022604 77 0.025
negative regulation of phosphorus metabolic process GO:0010563 80 0.025
metanephric tubule development GO:0072170 4 0.025
regulation of atp biosynthetic process GO:2001169 2 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
regulation of neuron death GO:1901214 115 0.024
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.024
protein oligomerization GO:0051259 191 0.024
ribonucleoside biosynthetic process GO:0042455 25 0.024
cellular response to lipid GO:0071396 201 0.024
positive regulation of signaling GO:0023056 270 0.024
response to organophosphorus GO:0046683 102 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.023
negative regulation of cell differentiation GO:0045596 99 0.023
purine ribonucleoside biosynthetic process GO:0046129 21 0.022
negative regulation of cellular component organization GO:0051129 83 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
regulation of cell development GO:0060284 263 0.022
cellular component movement GO:0006928 248 0.022
cellular response to organonitrogen compound GO:0071417 197 0.022
metanephric mesenchyme development GO:0072075 2 0.022
regulation of cellular localization GO:0060341 263 0.021
Human
cellular response to endogenous stimulus GO:0071495 377 0.021
neuron differentiation GO:0030182 368 0.021
regulation of response to stress GO:0080134 126 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.020
positive regulation of intracellular signal transduction GO:1902533 138 0.020
positive regulation of atp biosynthetic process GO:2001171 2 0.020
protein transport GO:0015031 132 0.020
Human
response to decreased oxygen levels GO:0036293 237 0.020
renal vesicle development GO:0072087 4 0.020
rhythmic process GO:0048511 156 0.020
regulation of hydrolase activity GO:0051336 143 0.019
negative regulation of innate immune response GO:0045824 4 0.019
organonitrogen compound biosynthetic process GO:1901566 167 0.019
regulation of phosphorylation GO:0042325 248 0.019
positive regulation of nucleoside metabolic process GO:0045979 55 0.019
glycosyl compound catabolic process GO:1901658 126 0.019
response to camp GO:0051591 91 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
positive regulation of i kappab kinase nf kappab signaling GO:0043123 8 0.018
nucleoside monophosphate biosynthetic process GO:0009124 28 0.018
antigen processing and presentation GO:0019882 2 0.018
protein complex assembly GO:0006461 263 0.018
regulation of nucleotide biosynthetic process GO:0030808 47 0.018
regulation of smooth muscle cell proliferation GO:0048660 75 0.018
organophosphate catabolic process GO:0046434 148 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
single organism intracellular transport GO:1902582 166 0.018
Human
cellular component biogenesis GO:0044085 368 0.018
Human
positive regulation of catalytic activity GO:0043085 184 0.018
mammary gland involution GO:0060056 5 0.017
nucleoside catabolic process GO:0009164 126 0.017
immune response GO:0006955 104 0.017
cellular response to oxidative stress GO:0034599 76 0.017
i kappab kinase nf kappab signaling GO:0007249 19 0.017
renal system development GO:0072001 67 0.017
programmed cell death GO:0012501 392 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
negative regulation of phosphorylation GO:0042326 57 0.017
muscle cell proliferation GO:0033002 84 0.017
response to hypoxia GO:0001666 231 0.017
cellular component morphogenesis GO:0032989 155 0.017
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
amine metabolic process GO:0009308 38 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
negative regulation of protein phosphorylation GO:0001933 44 0.016
response to insulin GO:0032868 133 0.016
negative regulation of epithelial cell differentiation GO:0030857 5 0.016
response to peptide GO:1901652 292 0.016
kidney epithelium development GO:0072073 19 0.016
single organism reproductive process GO:0044702 297 0.016
body fluid secretion GO:0007589 41 0.016
proteolysis GO:0006508 175 0.016
response to ethanol GO:0045471 162 0.016
positive regulation of molecular function GO:0044093 230 0.016
aromatic compound catabolic process GO:0019439 168 0.016
regulation of mitochondrial membrane permeability GO:0046902 5 0.016
membrane organization GO:0061024 94 0.016
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.015
purine nucleoside monophosphate biosynthetic process GO:0009127 20 0.015
kidney mesenchymal cell proliferation GO:0072135 1 0.015
reproduction GO:0000003 245 0.015
organic acid metabolic process GO:0006082 292 0.015
mitochondrion organization GO:0007005 35 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
chemical homeostasis GO:0048878 292 0.015
female sex differentiation GO:0046660 59 0.015
developmental process involved in reproduction GO:0003006 159 0.015
gland development GO:0048732 155 0.015
smooth muscle cell proliferation GO:0048659 77 0.015
purine containing compound catabolic process GO:0072523 138 0.015
inorganic ion transmembrane transport GO:0098660 229 0.014
neuron death GO:0070997 127 0.014
nephron tubule development GO:0072080 12 0.014
regulation of anatomical structure size GO:0090066 135 0.014
regulation of programmed cell death GO:0043067 341 0.014
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
renal vesicle morphogenesis GO:0072077 4 0.014
negative regulation of protein modification process GO:0031400 52 0.014
Human
positive regulation of apoptotic process GO:0043065 154 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
luteinization GO:0001553 8 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
regulation of protein localization GO:0032880 81 0.014
Human
negative regulation of transport GO:0051051 136 0.014
Human
positive regulation of transport GO:0051050 245 0.014
regulation of cellular component movement GO:0051270 150 0.014
single organism organelle organization GO:1902589 180 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 1 0.013
activation of immune response GO:0002253 26 0.013
nucleotide catabolic process GO:0009166 139 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
Human
regulation of cell projection organization GO:0031344 175 0.013
regulation of protein metabolic process GO:0051246 289 0.013
Human
multi organism reproductive process GO:0044703 262 0.013
response to reactive oxygen species GO:0000302 120 0.013
divalent inorganic cation transport GO:0072511 134 0.013
carboxylic acid metabolic process GO:0019752 289 0.013
head development GO:0060322 247 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
Human
neuron projection development GO:0031175 273 0.013
regulation of defense response GO:0031347 68 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
negative regulation of signaling GO:0023057 157 0.013
striated muscle cell proliferation GO:0014855 9 0.013
single organism catabolic process GO:0044712 283 0.013
immunoglobulin mediated immune response GO:0016064 4 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
heterocycle catabolic process GO:0046700 167 0.013
protein complex subunit organization GO:0071822 302 0.013
transmembrane transport GO:0055085 412 0.012
pigment biosynthetic process GO:0046148 4 0.012
metanephric nephron epithelium development GO:0072243 3 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
negative regulation of jak stat cascade GO:0046426 3 0.012
activation of cysteine type endopeptidase activity GO:0097202 4 0.012
cation transmembrane transport GO:0098655 263 0.012
single organism cellular localization GO:1902580 102 0.012
Human
intracellular transport GO:0046907 185 0.012
Human
negative regulation of molecular function GO:0044092 133 0.012
Human
cellular response to insulin stimulus GO:0032869 81 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
negative regulation of cell communication GO:0010648 158 0.012
neuron development GO:0048666 286 0.012
regulation of blood circulation GO:1903522 110 0.012
response to heat GO:0009408 60 0.012
glycosyl compound biosynthetic process GO:1901659 25 0.012
positive regulation of innate immune response GO:0045089 11 0.012
purine ribonucleoside monophosphate biosynthetic process GO:0009168 20 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
nephron epithelium development GO:0072009 14 0.011
regulation of neuron projection development GO:0010975 161 0.011
cellular protein localization GO:0034613 122 0.011
Human
negative regulation of hydrogen peroxide biosynthetic process GO:0010730 2 0.011
cell morphogenesis GO:0000902 142 0.011
negative regulation of intracellular signal transduction GO:1902532 38 0.011
regulation of system process GO:0044057 208 0.011
regulation of immune response GO:0050776 55 0.011
metal ion transport GO:0030001 289 0.011
immune response activating signal transduction GO:0002757 15 0.011
nitrogen compound transport GO:0071705 229 0.011
cell projection organization GO:0030030 302 0.011
regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 1 0.011
response to growth factor GO:0070848 189 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
Human
positive regulation of cellular component organization GO:0051130 200 0.010
cellular chemical homeostasis GO:0055082 247 0.010
peptidyl amino acid modification GO:0018193 126 0.010
sexual reproduction GO:0019953 148 0.010
metanephric nephron morphogenesis GO:0072273 6 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
urogenital system development GO:0001655 78 0.010
hepaticobiliary system development GO:0061008 90 0.010
hydrogen peroxide metabolic process GO:0042743 13 0.010
regulation of locomotion GO:0040012 148 0.010
regulation of protein modification process GO:0031399 194 0.010
Human
mammary gland development GO:0030879 38 0.010

LOC100362108 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
primary immunodeficiency disease DOID:612 0 0.028
severe combined immunodeficiency DOID:627 0 0.028
combined t cell and b cell immunodeficiency DOID:628 0 0.028
immune system disease DOID:2914 0 0.028
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.014
central nervous system disease DOID:331 0 0.013
disease of metabolism DOID:0014667 0 0.011