Rattus norvegicus

0 known processes

Sit1

signaling threshold regulating transmembrane adaptor 1

Sit1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.107
negative regulation of response to tumor cell GO:0002835 2 0.105
apoptotic process GO:0006915 381 0.088
response to biotic stimulus GO:0009607 226 0.080
regulation of rna biosynthetic process GO:2001141 381 0.077
rna metabolic process GO:0016070 406 0.070
negative regulation of cellular metabolic process GO:0031324 281 0.067
negative regulation of immune response to tumor cell GO:0002838 2 0.064
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.063
central nervous system development GO:0007417 311 0.059
regulation of apoptotic process GO:0042981 335 0.058
regulation of immune response to tumor cell GO:0002837 3 0.058
response to nutrient levels GO:0031667 370 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.049
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.049
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.048
response to bacterium GO:0009617 200 0.047
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.047
response to extracellular stimulus GO:0009991 380 0.045
regulation of programmed cell death GO:0043067 341 0.045
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.043
organophosphate metabolic process GO:0019637 370 0.039
organic substance catabolic process GO:1901575 316 0.038
programmed cell death GO:0012501 392 0.038
negative regulation of macromolecule metabolic process GO:0010605 260 0.038
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.037
catabolic process GO:0009056 351 0.037
regulation of nucleic acid templated transcription GO:1903506 380 0.037
positive regulation of biosynthetic process GO:0009891 319 0.037
response to tumor cell GO:0002347 4 0.037
monovalent inorganic cation transport GO:0015672 172 0.035
regulation of response to tumor cell GO:0002834 3 0.035
immune system process GO:0002376 204 0.034
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.034
negative regulation of cellular biosynthetic process GO:0031327 161 0.033
response to other organism GO:0051707 220 0.033
positive regulation of transcription dna templated GO:0045893 197 0.032
transcription dna templated GO:0006351 377 0.032
immune response to tumor cell GO:0002418 3 0.032
negative regulation of transcription dna templated GO:0045892 116 0.031
negative regulation of biosynthetic process GO:0009890 168 0.031
response to inorganic substance GO:0010035 377 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
regulation of cellular component movement GO:0051270 150 0.030
regulation of immune system process GO:0002682 123 0.030
regulation of cell motility GO:2000145 131 0.030
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.029
response to lipopolysaccharide GO:0032496 191 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.028
regulation of molecular function GO:0065009 398 0.028
regulation of transcription dna templated GO:0006355 374 0.027
positive regulation of rna metabolic process GO:0051254 203 0.027
immune response regulating signaling pathway GO:0002764 19 0.027
negative regulation of metabolic process GO:0009892 331 0.027
regulation of rna metabolic process GO:0051252 391 0.027
rna biosynthetic process GO:0032774 380 0.026
response to oxidative stress GO:0006979 186 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.025
negative regulation of rna metabolic process GO:0051253 123 0.025
response to external biotic stimulus GO:0043207 221 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
regulation of cell differentiation GO:0045595 320 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.024
negative regulation of programmed cell death GO:0043069 183 0.023
cell activation GO:0001775 97 0.023
proteolysis GO:0006508 175 0.023
organic acid metabolic process GO:0006082 292 0.023
cellular catabolic process GO:0044248 295 0.023
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.022
negative regulation of innate immune response GO:0045824 4 0.022
leukocyte activation GO:0045321 76 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
cell motility GO:0048870 202 0.021
negative regulation of gene expression GO:0010629 199 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
response to molecule of bacterial origin GO:0002237 194 0.021
cellular component movement GO:0006928 248 0.021
immune response GO:0006955 104 0.021
positive regulation of cellular component movement GO:0051272 102 0.021
head development GO:0060322 247 0.021
cellular amino acid metabolic process GO:0006520 107 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
purine containing compound metabolic process GO:0072521 253 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
heterocycle catabolic process GO:0046700 167 0.020
response to hydrogen peroxide GO:0042542 89 0.019
negative regulation of cell death GO:0060548 229 0.019
metal ion transport GO:0030001 289 0.019
regulation of locomotion GO:0040012 148 0.019
single organism biosynthetic process GO:0044711 342 0.019
regulation of immune response GO:0050776 55 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.018
response to hyperoxia GO:0055093 45 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
salivary gland morphogenesis GO:0007435 1 0.018
single organism catabolic process GO:0044712 283 0.018
aromatic compound catabolic process GO:0019439 168 0.018
regulation of cell proliferation GO:0042127 359 0.018
positive regulation of gene expression GO:0010628 244 0.017
antigen receptor mediated signaling pathway GO:0050851 1 0.017
response to oxygen levels GO:0070482 265 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
lymphocyte activation GO:0046649 43 0.017
protein complex biogenesis GO:0070271 263 0.017
aging GO:0007568 241 0.017
regulation of protein metabolic process GO:0051246 289 0.017
protein phosphorylation GO:0006468 345 0.017
macromolecular complex assembly GO:0065003 273 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
tissue development GO:0009888 252 0.016
nucleotide metabolic process GO:0009117 279 0.016
regulation of membrane potential GO:0042391 110 0.016
cellular ketone metabolic process GO:0042180 51 0.016
leukocyte cell cell adhesion GO:0007159 4 0.016
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.016
brain development GO:0007420 247 0.016
cellular component biogenesis GO:0044085 368 0.016
cellular amine metabolic process GO:0044106 38 0.016
urogenital system development GO:0001655 78 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
regulation of cytokine production GO:0001817 56 0.016
negative regulation of molecular function GO:0044092 133 0.015
regulation of cellular component organization GO:0051128 368 0.015
cellular response to stress GO:0033554 269 0.015
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.015
protein complex subunit organization GO:0071822 302 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
inflammatory response GO:0006954 150 0.015
response to reactive oxygen species GO:0000302 120 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
salivary gland development GO:0007431 3 0.015
response to wounding GO:0009611 254 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
positive regulation of transport GO:0051050 245 0.014
innate immune response GO:0045087 35 0.014
gland development GO:0048732 155 0.014
positive regulation of molecular function GO:0044093 230 0.014
response to increased oxygen levels GO:0036296 45 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
dna metabolic process GO:0006259 96 0.014
nucleoside metabolic process GO:0009116 179 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
positive regulation of immune system process GO:0002684 90 0.014
regulation of neurogenesis GO:0050767 247 0.014
homeostatic process GO:0042592 331 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
cellular component assembly GO:0022607 360 0.014
response to decreased oxygen levels GO:0036293 237 0.014
intracellular transport GO:0046907 185 0.013
nucleic acid templated transcription GO:0097659 379 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
cell adhesion GO:0007155 110 0.013
circulatory system development GO:0072359 134 0.013
response to nutrient GO:0007584 248 0.013
protein maturation GO:0051604 68 0.013
regulation of protein maturation GO:1903317 50 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
axis specification GO:0009798 4 0.013
regulation of cell migration GO:0030334 128 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
cell migration GO:0016477 197 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
regulation of catalytic activity GO:0050790 304 0.012
locomotion GO:0040011 237 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
biological adhesion GO:0022610 110 0.012
positive regulation of cell migration GO:0030335 96 0.012
regulation of cell cell adhesion GO:0022407 14 0.012
cellular response to molecule of bacterial origin GO:0071219 56 0.012
response to hypoxia GO:0001666 231 0.012
ras protein signal transduction GO:0007265 29 0.012
negative regulation of signaling GO:0023057 157 0.012
regulation of phosphorylation GO:0042325 248 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
negative regulation of response to biotic stimulus GO:0002832 4 0.012
organelle organization GO:0006996 266 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
fibrinolysis GO:0042730 2 0.012
single organismal cell cell adhesion GO:0016337 42 0.012
regulation of cell development GO:0060284 263 0.012
gliogenesis GO:0042063 93 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
protein complex assembly GO:0006461 263 0.012
wound healing GO:0042060 122 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.012
regulation of protein modification process GO:0031399 194 0.012
amine metabolic process GO:0009308 38 0.011
cell projection organization GO:0030030 302 0.011
single organism organelle organization GO:1902589 180 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
positive regulation of protein modification process GO:0031401 142 0.011
sensory perception of bitter taste GO:0050913 4 0.011
oxoacid metabolic process GO:0043436 290 0.011
protein processing GO:0016485 68 0.011
neuron projection development GO:0031175 273 0.011
cellular response to reactive oxygen species GO:0034614 55 0.011
negative regulation of developmental process GO:0051093 125 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
response to cytokine GO:0034097 215 0.011
response to acid chemical GO:0001101 222 0.011
establishment of protein localization GO:0045184 141 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
cardiovascular system development GO:0072358 134 0.011
activation of cysteine type endopeptidase activity GO:0097202 4 0.011
anion transmembrane transport GO:0098656 77 0.011
defense response GO:0006952 194 0.011
cation transport GO:0006812 382 0.011
negative regulation of fibrinolysis GO:0051918 2 0.011
localization of cell GO:0051674 202 0.011
gamete generation GO:0007276 124 0.010
positive regulation of developmental process GO:0051094 283 0.010
glomerular mesangial cell proliferation GO:0072110 4 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
response to vitamin GO:0033273 131 0.010
neuron development GO:0048666 286 0.010
macromolecular complex subunit organization GO:0043933 339 0.010
single organism intracellular transport GO:1902582 166 0.010
male gamete generation GO:0048232 99 0.010
single organism cell adhesion GO:0098602 46 0.010
lipid metabolic process GO:0006629 283 0.010

Sit1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.011