Rattus norvegicus

54 known processes

Clcnka

chloride channel Ka

(Aliases: Clcnk1,MGC93313)

Clcnka biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.243
regulation of nucleic acid templated transcription GO:1903506 380 0.227
response to peptide hormone GO:0043434 278 0.176
organic anion transport GO:0015711 132 0.153
positive regulation of transport GO:0051050 245 0.146
lipid metabolic process GO:0006629 283 0.140
response to cytokine GO:0034097 215 0.138
regulation of rna metabolic process GO:0051252 391 0.121
cellular response to nitrogen compound GO:1901699 210 0.120
cellular response to external stimulus GO:0071496 118 0.115
response to peptide GO:1901652 292 0.112
regulation of cellular localization GO:0060341 263 0.109
response to estradiol GO:0032355 164 0.104
response to metal ion GO:0010038 253 0.102
regeneration GO:0031099 163 0.098
regulation of transcription dna templated GO:0006355 374 0.096
regulation of rna biosynthetic process GO:2001141 381 0.093
positive regulation of signaling GO:0023056 270 0.090
response to extracellular stimulus GO:0009991 380 0.090
chemical homeostasis GO:0048878 292 0.088
rna metabolic process GO:0016070 406 0.087
positive regulation of rna biosynthetic process GO:1902680 197 0.085
positive regulation of hormone secretion GO:0046887 65 0.083
cation transport GO:0006812 382 0.082
oxoacid metabolic process GO:0043436 290 0.080
organic acid metabolic process GO:0006082 292 0.080
cellular response to organonitrogen compound GO:0071417 197 0.078
oxidation reduction process GO:0055114 304 0.068
response to insulin GO:0032868 133 0.067
multi organism reproductive process GO:0044703 262 0.067
response to monosaccharide GO:0034284 159 0.065
nucleic acid templated transcription GO:0097659 379 0.063
transmembrane transport GO:0055085 412 0.062
rna biosynthetic process GO:0032774 380 0.061
cellular response to metal ion GO:0071248 55 0.060
response to carbohydrate GO:0009743 183 0.060
ion homeostasis GO:0050801 212 0.059
anterior posterior pattern specification GO:0009952 1 0.058
transcription from rna polymerase ii promoter GO:0006366 252 0.057
response to estrogen GO:0043627 232 0.057
muscle system process GO:0003012 115 0.057
positive regulation of cellular biosynthetic process GO:0031328 295 0.057
regulation of ion transport GO:0043269 245 0.056
macromolecular complex subunit organization GO:0043933 339 0.056
positive regulation of biosynthetic process GO:0009891 319 0.055
cellular chemical homeostasis GO:0055082 247 0.055
cellular component assembly GO:0022607 360 0.055
cellular response to cytokine stimulus GO:0071345 127 0.054
cellular component biogenesis GO:0044085 368 0.052
acid secretion GO:0046717 48 0.052
monocarboxylic acid transport GO:0015718 52 0.051
positive regulation of transcription dna templated GO:0045893 197 0.051
cellular response to insulin stimulus GO:0032869 81 0.051
protein complex biogenesis GO:0070271 263 0.051
cellular response to oxygen containing compound GO:1901701 386 0.050
single organism behavior GO:0044708 130 0.050
negative regulation of cellular metabolic process GO:0031324 281 0.050
response to alkaloid GO:0043279 132 0.049
response to nutrient levels GO:0031667 370 0.048
behavior GO:0007610 205 0.047
tissue development GO:0009888 252 0.047
macromolecular complex assembly GO:0065003 273 0.046
cellular cation homeostasis GO:0030003 180 0.046
carboxylic acid metabolic process GO:0019752 289 0.046
response to vitamin GO:0033273 131 0.046
multicellular organismal reproductive process GO:0048609 233 0.046
response to hexose GO:0009746 144 0.044
positive regulation of gene expression GO:0010628 244 0.042
regulation of secretion by cell GO:1903530 208 0.041
cellular ion homeostasis GO:0006873 184 0.041
organ regeneration GO:0031100 101 0.039
cellular component movement GO:0006928 248 0.039
reproduction GO:0000003 245 0.039
response to glucocorticoid GO:0051384 223 0.039
lipid transport GO:0006869 61 0.039
negative regulation of metabolic process GO:0009892 331 0.038
response to mechanical stimulus GO:0009612 134 0.036
monocarboxylic acid metabolic process GO:0032787 152 0.035
negative regulation of rna biosynthetic process GO:1902679 118 0.035
positive regulation of secretion GO:0051047 140 0.035
monovalent inorganic cation transport GO:0015672 172 0.035
central nervous system development GO:0007417 311 0.034
cation homeostasis GO:0055080 195 0.034
cellular response to organic cyclic compound GO:0071407 202 0.033
regulation of blood pressure GO:0008217 83 0.033
regulation of cell proliferation GO:0042127 359 0.033
multicellular organismal signaling GO:0035637 44 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.032
secretion by cell GO:0032940 248 0.032
negative regulation of macromolecule metabolic process GO:0010605 260 0.032
multi multicellular organism process GO:0044706 138 0.032
aging GO:0007568 241 0.031
homeostatic process GO:0042592 331 0.031
response to oxidative stress GO:0006979 186 0.031
muscle structure development GO:0061061 87 0.030
regulation of secretion GO:0051046 224 0.030
positive regulation of ion transport GO:0043270 94 0.030
negative regulation of rna metabolic process GO:0051253 123 0.030
alkaloid metabolic process GO:0009820 3 0.029
positive regulation of cellular component organization GO:0051130 200 0.029
response to ethanol GO:0045471 162 0.029
hormone transport GO:0009914 121 0.029
rhythmic process GO:0048511 156 0.029
response to growth factor GO:0070848 189 0.029
protein oligomerization GO:0051259 191 0.028
circulatory system process GO:0003013 183 0.028
metal ion transport GO:0030001 289 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.028
cellular response to peptide GO:1901653 133 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.027
divalent inorganic cation homeostasis GO:0072507 165 0.027
cellular response to abiotic stimulus GO:0071214 85 0.027
response to sulfur dioxide GO:0010477 3 0.027
cellular component morphogenesis GO:0032989 155 0.027
response to molecule of bacterial origin GO:0002237 194 0.027
transcription dna templated GO:0006351 377 0.027
gamete generation GO:0007276 124 0.027
hormone secretion GO:0046879 115 0.027
cellular response to inorganic substance GO:0071241 65 0.027
cellular response to extracellular stimulus GO:0031668 73 0.026
icosanoid metabolic process GO:0006690 38 0.026
negative regulation of nucleic acid templated transcription GO:1903507 117 0.026
protein complex subunit organization GO:0071822 302 0.026
fatty acid metabolic process GO:0006631 99 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.026
organic hydroxy compound biosynthetic process GO:1901617 51 0.026
regulation of systemic arterial blood pressure GO:0003073 30 0.026
cardiac chamber development GO:0003205 1 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
cellular response to stress GO:0033554 269 0.025
response to toxic substance GO:0009636 133 0.025
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
positive regulation of cell death GO:0010942 184 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
reproductive process GO:0022414 372 0.024
cellular homeostasis GO:0019725 252 0.024
response to corticosteroid GO:0031960 235 0.024
response to reactive oxygen species GO:0000302 120 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
positive regulation of apoptotic process GO:0043065 154 0.024
single organism intracellular transport GO:1902582 166 0.024
feeding behavior GO:0007631 53 0.024
muscle cell differentiation GO:0042692 52 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
cellular divalent inorganic cation homeostasis GO:0072503 162 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.023
cellular ketone metabolic process GO:0042180 51 0.023
sexual reproduction GO:0019953 148 0.022
multicellular organism reproduction GO:0032504 233 0.022
cellular amino acid metabolic process GO:0006520 107 0.022
negative regulation of cell death GO:0060548 229 0.022
regulation of blood circulation GO:1903522 110 0.022
regulation of cellular component movement GO:0051270 150 0.022
regulation of muscle system process GO:0090257 79 0.022
metal ion homeostasis GO:0055065 186 0.022
signal release GO:0023061 145 0.021
cation transmembrane transport GO:0098655 263 0.021
negative regulation of signaling GO:0023057 157 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.021
cellular amine metabolic process GO:0044106 38 0.021
cellular response to lipid GO:0071396 201 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
amine metabolic process GO:0009308 38 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
positive regulation of rna metabolic process GO:0051254 203 0.020
response to glucose GO:0009749 136 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.020
protein homooligomerization GO:0051260 91 0.020
response to oxygen levels GO:0070482 265 0.019
membrane repolarization GO:0086009 1 0.019
positive regulation of heart contraction GO:0045823 15 0.019
response to activity GO:0014823 73 0.019
steroid metabolic process GO:0008202 73 0.019
reactive oxygen species metabolic process GO:0072593 37 0.019
regulation of immunoglobulin production GO:0002637 4 0.019
g protein coupled receptor signaling pathway GO:0007186 242 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.018
negative regulation of transcription dna templated GO:0045892 116 0.018
regulation of membrane potential GO:0042391 110 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
neurological system process GO:0050877 219 0.018
adenohypophysis development GO:0021984 2 0.018
defecation GO:0030421 1 0.018
kidney development GO:0001822 67 0.018
response to temperature stimulus GO:0009266 94 0.018
heart contraction GO:0060047 57 0.018
response to decreased oxygen levels GO:0036293 237 0.018
divalent metal ion transport GO:0070838 132 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
action potential GO:0001508 54 0.017
response to zinc ion GO:0010043 39 0.017
negative regulation of gene expression GO:0010629 199 0.017
organic acid transport GO:0015849 116 0.017
sequestering of calcium ion GO:0051208 8 0.017
head development GO:0060322 247 0.017
response to ammonium ion GO:0060359 71 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.016
unsaturated fatty acid metabolic process GO:0033559 39 0.016
cellular lipid metabolic process GO:0044255 208 0.016
regulation of peptide transport GO:0090087 87 0.016
regulation of calcium ion transport GO:0051924 77 0.016
positive regulation of organelle organization GO:0010638 48 0.016
transmission of nerve impulse GO:0019226 42 0.016
sensory perception GO:0007600 101 0.016
cellular response to nutrient levels GO:0031669 60 0.016
regulation of signal transduction GO:0009966 318 0.016
small molecule biosynthetic process GO:0044283 124 0.016
regulation of neurological system process GO:0031644 43 0.015
apoptotic process GO:0006915 381 0.015
organic hydroxy compound metabolic process GO:1901615 115 0.015
lipid biosynthetic process GO:0008610 128 0.015
blood circulation GO:0008015 183 0.015
response to vitamin d GO:0033280 34 0.015
negative regulation of transport GO:0051051 136 0.015
regulation of catalytic activity GO:0050790 304 0.015
regulation of blood vessel size GO:0050880 89 0.015
multicellular organismal water homeostasis GO:0050891 4 0.015
sequestering of metal ion GO:0051238 9 0.015
nitrogen compound transport GO:0071705 229 0.015
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.015
positive regulation of transmembrane transport GO:0034764 25 0.015
regulation of hormone levels GO:0010817 187 0.015
cell growth GO:0016049 104 0.015
anion transport GO:0006820 178 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
heart process GO:0003015 57 0.014
dna metabolic process GO:0006259 96 0.014
regulation of tube size GO:0035150 89 0.014
response to vitamin e GO:0033197 24 0.014
negative regulation of secretion GO:0051048 82 0.014
limb morphogenesis GO:0035108 4 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
single organism catabolic process GO:0044712 283 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
neuron differentiation GO:0030182 368 0.014
liver development GO:0001889 90 0.014
response to organophosphorus GO:0046683 102 0.014
endocrine process GO:0050886 32 0.014
programmed cell death GO:0012501 392 0.014
cellular protein localization GO:0034613 122 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
endocytosis GO:0006897 84 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
regulation of multicellular organismal development GO:2000026 376 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
regulation of skeletal muscle tissue growth GO:0048631 3 0.013
cardiovascular system development GO:0072358 134 0.013
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.013
regulation of peptide secretion GO:0002791 82 0.013
cellular response to drug GO:0035690 30 0.013
cytoplasmic transport GO:0016482 115 0.013
cellular response to mechanical stimulus GO:0071260 48 0.013
axis specification GO:0009798 4 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.013
glycerolipid metabolic process GO:0046486 67 0.013
bmp signaling pathway GO:0030509 4 0.013
cell communication involved in cardiac conduction GO:0086065 2 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
response to nicotine GO:0035094 51 0.013
regulation of transporter activity GO:0032409 50 0.013
regulation of body fluid levels GO:0050878 90 0.013
cellular calcium ion homeostasis GO:0006874 160 0.012
cardiac muscle cell contraction GO:0086003 10 0.012
acylglycerol metabolic process GO:0006639 21 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
lipid localization GO:0010876 62 0.012
heart morphogenesis GO:0003007 3 0.012
response to acid chemical GO:0001101 222 0.012
cellular catabolic process GO:0044248 295 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
smooth muscle contraction GO:0006939 37 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
positive regulation of camp metabolic process GO:0030816 31 0.012
positive regulation of developmental process GO:0051094 283 0.012
neuronal action potential GO:0019228 35 0.012
adenine nucleotide transport GO:0051503 2 0.012
response to purine containing compound GO:0014074 126 0.012
cellular response to tumor necrosis factor GO:0071356 46 0.012
regulation of organic acid transport GO:0032890 35 0.012
response to nutrient GO:0007584 248 0.012
potassium ion transport GO:0006813 97 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
cardiac ventricle development GO:0003231 1 0.012
organic hydroxy compound transport GO:0015850 77 0.012
cell projection organization GO:0030030 302 0.012
growth GO:0040007 165 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
response to hyperoxia GO:0055093 45 0.012
circulatory system development GO:0072359 134 0.011
response to hydrogen peroxide GO:0042542 89 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
response to calcium ion GO:0051592 59 0.011
fatty acid derivative metabolic process GO:1901568 38 0.011
catabolic process GO:0009056 351 0.011
regulation of dna metabolic process GO:0051052 60 0.011
cellular potassium ion transport GO:0071804 72 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
regulation of apoptotic process GO:0042981 335 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
regulation of system process GO:0044057 208 0.011
regulation of potassium ion transport GO:0043266 29 0.011
positive regulation of cell growth GO:0030307 44 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
mapk cascade GO:0000165 140 0.011
calcium ion transport GO:0006816 131 0.011
regulation of heart contraction GO:0008016 48 0.011
divalent inorganic cation transport GO:0072511 134 0.011
male gamete generation GO:0048232 99 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
muscle tissue development GO:0060537 58 0.011
peptide hormone secretion GO:0030072 84 0.011
renal system process GO:0003014 40 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
cell morphogenesis GO:0000902 142 0.011
response to osmotic stress GO:0006970 42 0.011
regulation of catabolic process GO:0009894 113 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
response to starvation GO:0042594 59 0.011
response to lipopolysaccharide GO:0032496 191 0.011
calcium ion homeostasis GO:0055074 162 0.011
carboxylic acid transport GO:0046942 115 0.011
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.011
intracellular transport GO:0046907 185 0.011
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
regulation of cell motility GO:2000145 131 0.010
regulation of ion homeostasis GO:2000021 63 0.010
nucleotide metabolic process GO:0009117 279 0.010
chemosensory behavior GO:0007635 2 0.010
amide transport GO:0042886 105 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
hepaticobiliary system development GO:0061008 90 0.010
circadian rhythm GO:0007623 88 0.010
regulation of immune response GO:0050776 55 0.010
spermatogenesis GO:0007283 99 0.010
secretion GO:0046903 307 0.010
organelle organization GO:0006996 266 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010

Clcnka disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
long qt syndrome DOID:2843 0 0.017
disease of anatomical entity DOID:7 0 0.010
Human
central nervous system disease DOID:331 0 0.010
nervous system disease DOID:863 0 0.010