Rattus norvegicus

0 known processes

Ndrg1

N-myc downstream regulated 1

(Aliases: Ndr1)

Ndrg1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.121
programmed cell death GO:0012501 392 0.113
regulation of programmed cell death GO:0043067 341 0.097
apoptotic process GO:0006915 381 0.083
oxoacid metabolic process GO:0043436 290 0.080
regulation of cellular localization GO:0060341 263 0.077
response to hypoxia GO:0001666 231 0.070
carboxylic acid metabolic process GO:0019752 289 0.067
positive regulation of cell death GO:0010942 184 0.065
neuron differentiation GO:0030182 368 0.064
Rat
secretion by cell GO:0032940 248 0.064
regulation of cellular component organization GO:0051128 368 0.060
Rat
regulation of cell proliferation GO:0042127 359 0.057
response to inorganic substance GO:0010035 377 0.057
cellular amino acid metabolic process GO:0006520 107 0.055
regulation of secretion GO:0051046 224 0.053
regulation of neurogenesis GO:0050767 247 0.050
Rat
reproductive process GO:0022414 372 0.049
response to decreased oxygen levels GO:0036293 237 0.048
regulation of apoptotic process GO:0042981 335 0.048
cellular response to oxygen containing compound GO:1901701 386 0.047
cellular amine metabolic process GO:0044106 38 0.047
cellular ketone metabolic process GO:0042180 51 0.047
negative regulation of metabolic process GO:0009892 331 0.046
regulation of protein metabolic process GO:0051246 289 0.045
secretion GO:0046903 307 0.045
positive regulation of multicellular organismal process GO:0051240 387 0.044
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.044
regulation of cellular amine metabolic process GO:0033238 8 0.042
central nervous system development GO:0007417 311 0.042
Rat
regulation of secretion by cell GO:1903530 208 0.042
regulation of neuron projection development GO:0010975 161 0.041
Rat
anatomical structure morphogenesis GO:0009653 298 0.041
multi organism reproductive process GO:0044703 262 0.041
protein complex subunit organization GO:0071822 302 0.041
regulation of system process GO:0044057 208 0.040
macromolecular complex subunit organization GO:0043933 339 0.040
neuron development GO:0048666 286 0.040
Rat
response to oxygen levels GO:0070482 265 0.039
response to extracellular stimulus GO:0009991 380 0.038
cell projection organization GO:0030030 302 0.037
Rat
amine metabolic process GO:0009308 38 0.037
chemical homeostasis GO:0048878 292 0.036
response to nutrient levels GO:0031667 370 0.036
cardiovascular system development GO:0072358 134 0.036
homeostatic process GO:0042592 331 0.035
biological adhesion GO:0022610 110 0.035
protein phosphorylation GO:0006468 345 0.035
neuron projection development GO:0031175 273 0.035
Rat
cell cell signaling GO:0007267 335 0.035
negative regulation of cell proliferation GO:0008285 119 0.035
regulation of cellular ketone metabolic process GO:0010565 27 0.034
positive regulation of cell proliferation GO:0008284 249 0.034
response to peptide hormone GO:0043434 278 0.034
regulation of nervous system development GO:0051960 264 0.034
Rat
regulation of cell differentiation GO:0045595 320 0.034
Rat
cellular response to endogenous stimulus GO:0071495 377 0.033
metal ion transport GO:0030001 289 0.032
single organism reproductive process GO:0044702 297 0.032
cellular response to hormone stimulus GO:0032870 247 0.032
head development GO:0060322 247 0.032
Rat
blood circulation GO:0008015 183 0.031
single organism biosynthetic process GO:0044711 342 0.031
organic substance catabolic process GO:1901575 316 0.031
cellular component assembly GO:0022607 360 0.030
positive regulation of apoptotic process GO:0043065 154 0.030
response to estrogen GO:0043627 232 0.030
response to oxidative stress GO:0006979 186 0.029
response to peptide GO:1901652 292 0.029
positive regulation of transport GO:0051050 245 0.029
anion transport GO:0006820 178 0.029
negative regulation of multicellular organismal process GO:0051241 203 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
cellular component biogenesis GO:0044085 368 0.028
circulatory system process GO:0003013 183 0.028
lipid metabolic process GO:0006629 283 0.028
response to glucocorticoid GO:0051384 223 0.028
cellular catabolic process GO:0044248 295 0.028
positive regulation of protein metabolic process GO:0051247 178 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.027
nucleic acid templated transcription GO:0097659 379 0.027
catabolic process GO:0009056 351 0.027
response to hexose GO:0009746 144 0.027
positive regulation of programmed cell death GO:0043068 157 0.027
cation transport GO:0006812 382 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
regulation of cell development GO:0060284 263 0.027
Rat
positive regulation of cell differentiation GO:0045597 217 0.027
Rat
negative regulation of cell death GO:0060548 229 0.027
regulation of neuron differentiation GO:0045664 208 0.026
Rat
regulation of molecular function GO:0065009 398 0.026
response to wounding GO:0009611 254 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
response to metal ion GO:0010038 253 0.025
regulation of cell projection organization GO:0031344 175 0.025
Rat
vesicle mediated transport GO:0016192 181 0.025
protein complex assembly GO:0006461 263 0.025
cellular divalent inorganic cation homeostasis GO:0072503 162 0.025
cation homeostasis GO:0055080 195 0.025
hormone secretion GO:0046879 115 0.024
nitrogen compound transport GO:0071705 229 0.024
cellular homeostasis GO:0019725 252 0.024
regulation of hormone levels GO:0010817 187 0.024
regulation of protein modification process GO:0031399 194 0.024
negative regulation of apoptotic process GO:0043066 181 0.024
regulation of membrane potential GO:0042391 110 0.024
response to alkaloid GO:0043279 132 0.024
response to corticosteroid GO:0031960 235 0.024
organophosphate metabolic process GO:0019637 370 0.023
regulation of phosphate metabolic process GO:0019220 349 0.023
positive regulation of developmental process GO:0051094 283 0.023
Rat
multi multicellular organism process GO:0044706 138 0.023
regulation of rna metabolic process GO:0051252 391 0.023
localization of cell GO:0051674 202 0.023
response to ketone GO:1901654 182 0.023
regulation of blood pressure GO:0008217 83 0.023
response to biotic stimulus GO:0009607 226 0.023
nucleotide metabolic process GO:0009117 279 0.023
heart morphogenesis GO:0003007 3 0.023
hormone transport GO:0009914 121 0.023
transmembrane transport GO:0055085 412 0.023
regulation of multicellular organismal development GO:2000026 376 0.022
Rat
negative regulation of programmed cell death GO:0043069 183 0.022
response to nutrient GO:0007584 248 0.022
regulation of phosphorylation GO:0042325 248 0.022
multicellular organism reproduction GO:0032504 233 0.022
negative regulation of molecular function GO:0044092 133 0.021
locomotion GO:0040011 237 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
cell adhesion GO:0007155 110 0.021
cellular chemical homeostasis GO:0055082 247 0.021
cellular ion homeostasis GO:0006873 184 0.021
signal release GO:0023061 145 0.021
regulation of vesicle mediated transport GO:0060627 81 0.021
response to external biotic stimulus GO:0043207 221 0.021
behavior GO:0007610 205 0.021
brain development GO:0007420 247 0.021
Rat
aging GO:0007568 241 0.021
cellular response to stress GO:0033554 269 0.021
cellular response to nitrogen compound GO:1901699 210 0.020
response to lipopolysaccharide GO:0032496 191 0.020
negative regulation of transport GO:0051051 136 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
ion transmembrane transport GO:0034220 365 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.019
calcium ion homeostasis GO:0055074 162 0.019
cell motility GO:0048870 202 0.019
amide transport GO:0042886 105 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
neuron death GO:0070997 127 0.019
positive regulation of cell communication GO:0010647 271 0.019
Fly
inflammatory response GO:0006954 150 0.019
cation transmembrane transport GO:0098655 263 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
Rat
cellular cation homeostasis GO:0030003 180 0.019
single organism catabolic process GO:0044712 283 0.019
peptidyl amino acid modification GO:0018193 126 0.019
rna metabolic process GO:0016070 406 0.019
female pregnancy GO:0007565 122 0.019
circulatory system development GO:0072359 134 0.019
regulation of body fluid levels GO:0050878 90 0.019
protein complex biogenesis GO:0070271 263 0.018
positive regulation of neurogenesis GO:0050769 165 0.018
Rat
regeneration GO:0031099 163 0.018
reproduction GO:0000003 245 0.018
defense response GO:0006952 194 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
positive regulation of cell development GO:0010720 176 0.018
Rat
response to acid chemical GO:0001101 222 0.018
response to other organism GO:0051707 220 0.017
epithelium development GO:0060429 96 0.017
membrane organization GO:0061024 94 0.017
proteolysis GO:0006508 175 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
macromolecular complex assembly GO:0065003 273 0.017
response to reactive oxygen species GO:0000302 120 0.017
gland development GO:0048732 155 0.017
cellular component movement GO:0006928 248 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
transmission of nerve impulse GO:0019226 42 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
actin filament based process GO:0030029 86 0.017
regulation of response to external stimulus GO:0032101 106 0.017
cell migration GO:0016477 197 0.016
positive regulation of secretion by cell GO:1903532 128 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
organelle organization GO:0006996 266 0.016
negative regulation of signaling GO:0023057 157 0.016
negative regulation of cell communication GO:0010648 158 0.016
action potential GO:0001508 54 0.016
intracellular signal transduction GO:0035556 314 0.016
Fly
organ regeneration GO:0031100 101 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
transcription dna templated GO:0006351 377 0.016
ion homeostasis GO:0050801 212 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
response to insulin GO:0032868 133 0.016
positive regulation of protein modification process GO:0031401 142 0.016
cellular response to lipid GO:0071396 201 0.016
response to glucose GO:0009749 136 0.016
cellular lipid metabolic process GO:0044255 208 0.016
cellular response to organic cyclic compound GO:0071407 202 0.015
positive regulation of secretion GO:0051047 140 0.015
alpha amino acid metabolic process GO:1901605 71 0.015
regulation of blood vessel size GO:0050880 89 0.015
negative regulation of secretion GO:0051048 82 0.015
regulation of catalytic activity GO:0050790 304 0.015
regulation of rna biosynthetic process GO:2001141 381 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
protein oligomerization GO:0051259 191 0.015
positive regulation of molecular function GO:0044093 230 0.015
multicellular organismal signaling GO:0035637 44 0.015
purine containing compound metabolic process GO:0072521 253 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
Rat
sexual reproduction GO:0019953 148 0.015
single organism organelle organization GO:1902589 180 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
regulation of blood circulation GO:1903522 110 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
regulation of anatomical structure size GO:0090066 135 0.015
cell morphogenesis GO:0000902 142 0.015
response to bacterium GO:0009617 200 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.014
calcium ion transport GO:0006816 131 0.014
small molecule biosynthetic process GO:0044283 124 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
Fly
response to molecule of bacterial origin GO:0002237 194 0.014
regulation of nucleic acid templated transcription GO:1903506 380 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
oxidation reduction process GO:0055114 304 0.014
tissue development GO:0009888 252 0.014
regulation of hormone secretion GO:0046883 106 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
macromolecule localization GO:0033036 252 0.014
organic anion transport GO:0015711 132 0.014
intracellular transport GO:0046907 185 0.014
neurological system process GO:0050877 219 0.013
response to purine containing compound GO:0014074 126 0.013
response to carbohydrate GO:0009743 183 0.013
cellular component morphogenesis GO:0032989 155 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
Fly
regulation of cell activation GO:0050865 50 0.013
actin cytoskeleton organization GO:0030036 73 0.013
cell part morphogenesis GO:0032990 123 0.013
growth GO:0040007 165 0.013
positive regulation of signaling GO:0023056 270 0.013
Fly
response to ammonium ion GO:0060359 71 0.013
insulin secretion GO:0030073 69 0.013
single organism intracellular transport GO:1902582 166 0.013
protein localization GO:0008104 191 0.013
response to starvation GO:0042594 59 0.013
cell type specific apoptotic process GO:0097285 134 0.013
metal ion homeostasis GO:0055065 186 0.013
peptide hormone secretion GO:0030072 84 0.013
ras protein signal transduction GO:0007265 29 0.013
Fly
regulation of tube size GO:0035150 89 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
nucleoside metabolic process GO:0009116 179 0.013
cellular response to peptide GO:1901653 133 0.013
aromatic compound catabolic process GO:0019439 168 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
negative regulation of signal transduction GO:0009968 83 0.013
gamete generation GO:0007276 124 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
cell activation GO:0001775 97 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
neuron fate commitment GO:0048663 4 0.012
renal system development GO:0072001 67 0.012
reproductive structure development GO:0048608 128 0.012
neuronal action potential GO:0019228 35 0.012
cellular response to external stimulus GO:0071496 118 0.012
establishment of protein localization GO:0045184 141 0.012
regulation of ion transport GO:0043269 245 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
carboxylic acid biosynthetic process GO:0046394 83 0.012
positive regulation of signal transduction GO:0009967 175 0.012
Fly
cytosolic calcium ion homeostasis GO:0051480 140 0.012
regulation of synaptic transmission GO:0050804 141 0.012
regulation of transferase activity GO:0051338 123 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
Fly
negative regulation of cell development GO:0010721 82 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
Rat
positive regulation of nervous system development GO:0051962 178 0.012
Rat
regulation of peptide transport GO:0090087 87 0.012
blood vessel development GO:0001568 69 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
protein homooligomerization GO:0051260 91 0.012
divalent inorganic cation transport GO:0072511 134 0.012
regulation of hydrolase activity GO:0051336 143 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
synaptic transmission glutamatergic GO:0035249 33 0.012
urogenital system development GO:0001655 78 0.012
response to monosaccharide GO:0034284 159 0.012
synaptic transmission GO:0007268 235 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
response to ethanol GO:0045471 162 0.011
vascular process in circulatory system GO:0003018 96 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
peptide secretion GO:0002790 86 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
negative regulation of gene expression GO:0010629 199 0.011
steroid metabolic process GO:0008202 73 0.011
response to organophosphorus GO:0046683 102 0.011
organic acid biosynthetic process GO:0016053 83 0.011
regulation of cell growth GO:0001558 85 0.011
cellular response to alcohol GO:0097306 87 0.011
organophosphate catabolic process GO:0046434 148 0.011
regulation of catabolic process GO:0009894 113 0.011
protein maturation GO:0051604 68 0.011
heart process GO:0003015 57 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
male gamete generation GO:0048232 99 0.011
exocytosis GO:0006887 60 0.011
development of primary sexual characteristics GO:0045137 107 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
regulation of cell motility GO:2000145 131 0.011
regulation of signal transduction GO:0009966 318 0.011
Fly
response to growth factor GO:0070848 189 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
dendrite development GO:0016358 72 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
cellular response to oxidative stress GO:0034599 76 0.011
anterior posterior pattern specification GO:0009952 1 0.011
regulation of protein localization GO:0032880 81 0.010
gastrulation GO:0007369 2 0.010
organic acid transport GO:0015849 116 0.010
response to estradiol GO:0032355 164 0.010
smooth muscle cell proliferation GO:0048659 77 0.010
regulation of insulin secretion GO:0050796 65 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
regulation of neuron death GO:1901214 115 0.010
regulation of transcription dna templated GO:0006355 374 0.010
response to toxic substance GO:0009636 133 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
negative regulation of developmental process GO:0051093 125 0.010
axis specification GO:0009798 4 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
cell growth GO:0016049 104 0.010
muscle system process GO:0003012 115 0.010
regulation of peptide secretion GO:0002791 82 0.010
inorganic ion transmembrane transport GO:0098660 229 0.010
negative regulation of catalytic activity GO:0043086 103 0.010

Ndrg1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
disease of metabolism DOID:0014667 0 0.011
sensory system disease DOID:0050155 0 0.011
central nervous system disease DOID:331 0 0.011
disease of cellular proliferation DOID:14566 0 0.010