Rattus norvegicus

0 known processes

Lingo3

leucine rich repeat and Ig domain containing 3

Lingo3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna biosynthetic process GO:0032774 380 0.052
nucleic acid templated transcription GO:0097659 379 0.049
rna metabolic process GO:0016070 406 0.047
regulation of cell proliferation GO:0042127 359 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.044
regulation of rna biosynthetic process GO:2001141 381 0.044
oxoacid metabolic process GO:0043436 290 0.042
regulation of cellular component organization GO:0051128 368 0.042
regulation of rna metabolic process GO:0051252 391 0.042
transcription dna templated GO:0006351 377 0.041
neuron differentiation GO:0030182 368 0.041
regulation of molecular function GO:0065009 398 0.041
cellular response to oxygen containing compound GO:1901701 386 0.039
regulation of multicellular organismal development GO:2000026 376 0.039
regulation of cell differentiation GO:0045595 320 0.039
regulation of signal transduction GO:0009966 318 0.037
carbohydrate derivative metabolic process GO:1901135 346 0.037
response to inorganic substance GO:0010035 377 0.036
cellular response to endogenous stimulus GO:0071495 377 0.035
single organism reproductive process GO:0044702 297 0.035
regulation of nucleic acid templated transcription GO:1903506 380 0.035
positive regulation of developmental process GO:0051094 283 0.035
response to extracellular stimulus GO:0009991 380 0.034
organic acid metabolic process GO:0006082 292 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.034
carboxylic acid metabolic process GO:0019752 289 0.033
positive regulation of multicellular organismal process GO:0051240 387 0.033
protein phosphorylation GO:0006468 345 0.032
regulation of cellular ketone metabolic process GO:0010565 27 0.032
cell cell signaling GO:0007267 335 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
reproductive process GO:0022414 372 0.032
secretion GO:0046903 307 0.032
negative regulation of metabolic process GO:0009892 331 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
response to nutrient levels GO:0031667 370 0.032
cell projection organization GO:0030030 302 0.032
regulation of phosphate metabolic process GO:0019220 349 0.032
regulation of apoptotic process GO:0042981 335 0.031
cellular amine metabolic process GO:0044106 38 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
cation transport GO:0006812 382 0.030
homeostatic process GO:0042592 331 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.030
central nervous system development GO:0007417 311 0.030
multi organism reproductive process GO:0044703 262 0.030
neuron projection development GO:0031175 273 0.029
positive regulation of cell proliferation GO:0008284 249 0.029
neuron development GO:0048666 286 0.029
transcription from rna polymerase ii promoter GO:0006366 252 0.029
regulation of catalytic activity GO:0050790 304 0.029
cellular ketone metabolic process GO:0042180 51 0.029
chemical homeostasis GO:0048878 292 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.029
intracellular signal transduction GO:0035556 314 0.029
apoptotic process GO:0006915 381 0.029
regulation of cellular localization GO:0060341 263 0.029
amine metabolic process GO:0009308 38 0.028
regulation of protein metabolic process GO:0051246 289 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
anatomical structure morphogenesis GO:0009653 298 0.028
cellular component assembly GO:0022607 360 0.028
programmed cell death GO:0012501 392 0.028
positive regulation of cell differentiation GO:0045597 217 0.027
locomotion GO:0040011 237 0.027
positive regulation of molecular function GO:0044093 230 0.027
cellular component movement GO:0006928 248 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
regulation of cell development GO:0060284 263 0.027
regulation of transcription dna templated GO:0006355 374 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
single organism biosynthetic process GO:0044711 342 0.026
regulation of nervous system development GO:0051960 264 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
reproduction GO:0000003 245 0.025
regulation of neurogenesis GO:0050767 247 0.024
brain development GO:0007420 247 0.024
cellular component biogenesis GO:0044085 368 0.024
g protein coupled receptor signaling pathway GO:0007186 242 0.024
synaptic transmission GO:0007268 235 0.024
purine containing compound metabolic process GO:0072521 253 0.024
positive regulation of cell communication GO:0010647 271 0.024
cellular homeostasis GO:0019725 252 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
single organism catabolic process GO:0044712 283 0.023
response to wounding GO:0009611 254 0.023
positive regulation of signaling GO:0023056 270 0.023
transmembrane transport GO:0055085 412 0.023
regulation of programmed cell death GO:0043067 341 0.023
secretion by cell GO:0032940 248 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
cellular chemical homeostasis GO:0055082 247 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.022
macromolecular complex subunit organization GO:0043933 339 0.022
positive regulation of gene expression GO:0010628 244 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
positive regulation of transport GO:0051050 245 0.022
metal ion transport GO:0030001 289 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
ion homeostasis GO:0050801 212 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
negative regulation of gene expression GO:0010629 199 0.022
cell motility GO:0048870 202 0.022
head development GO:0060322 247 0.022
cell migration GO:0016477 197 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
response to peptide GO:1901652 292 0.022
regulation of secretion by cell GO:1903530 208 0.022
regulation of neuron differentiation GO:0045664 208 0.022
blood circulation GO:0008015 183 0.021
catabolic process GO:0009056 351 0.021
response to corticosteroid GO:0031960 235 0.021
localization of cell GO:0051674 202 0.021
response to glucocorticoid GO:0051384 223 0.021
neurological system process GO:0050877 219 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
cation homeostasis GO:0055080 195 0.021
macromolecular complex assembly GO:0065003 273 0.021
organelle organization GO:0006996 266 0.021
organophosphate metabolic process GO:0019637 370 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
cellular response to stress GO:0033554 269 0.021
ion transmembrane transport GO:0034220 365 0.021
response to growth factor GO:0070848 189 0.021
nucleotide metabolic process GO:0009117 279 0.021
immune system process GO:0002376 204 0.021
regulation of phosphorylation GO:0042325 248 0.020
macromolecule localization GO:0033036 252 0.020
response to estrogen GO:0043627 232 0.020
protein complex biogenesis GO:0070271 263 0.020
negative regulation of cell death GO:0060548 229 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
protein complex assembly GO:0006461 263 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
multicellular organism reproduction GO:0032504 233 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
response to oxygen levels GO:0070482 265 0.020
response to peptide hormone GO:0043434 278 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
lipid metabolic process GO:0006629 283 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
regulation of ion transport GO:0043269 245 0.019
regulation of secretion GO:0051046 224 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
calcium ion homeostasis GO:0055074 162 0.019
tissue development GO:0009888 252 0.019
response to nutrient GO:0007584 248 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
aging GO:0007568 241 0.019
response to hypoxia GO:0001666 231 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
metal ion homeostasis GO:0055065 186 0.019
single organism intracellular transport GO:1902582 166 0.019
response to metal ion GO:0010038 253 0.019
regulation of system process GO:0044057 208 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
cellular catabolic process GO:0044248 295 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
response to decreased oxygen levels GO:0036293 237 0.018
regulation of protein modification process GO:0031399 194 0.018
response to oxidative stress GO:0006979 186 0.018
response to lipopolysaccharide GO:0032496 191 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
positive regulation of cell development GO:0010720 176 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
protein complex subunit organization GO:0071822 302 0.018
cellular cation homeostasis GO:0030003 180 0.018
positive regulation of neurogenesis GO:0050769 165 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
regulation of hormone levels GO:0010817 187 0.018
oxidation reduction process GO:0055114 304 0.018
regulation of neuron projection development GO:0010975 161 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
organic substance catabolic process GO:1901575 316 0.018
response to other organism GO:0051707 220 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
positive regulation of cell death GO:0010942 184 0.018
cellular response to lipid GO:0071396 201 0.018
cellular response to nitrogen compound GO:1901699 210 0.017
regulation of locomotion GO:0040012 148 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
regulation of cell projection organization GO:0031344 175 0.017
response to acid chemical GO:0001101 222 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
sexual reproduction GO:0019953 148 0.017
cellular ion homeostasis GO:0006873 184 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
response to biotic stimulus GO:0009607 226 0.017
intracellular transport GO:0046907 185 0.017
circulatory system process GO:0003013 183 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
heart morphogenesis GO:0003007 3 0.017
positive regulation of protein modification process GO:0031401 142 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
response to estradiol GO:0032355 164 0.016
regulation of transferase activity GO:0051338 123 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
nitrogen compound transport GO:0071705 229 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
negative regulation of developmental process GO:0051093 125 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.016
behavior GO:0007610 205 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
response to external biotic stimulus GO:0043207 221 0.016
negative regulation of signaling GO:0023057 157 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.015
rhythmic process GO:0048511 156 0.015
response to bacterium GO:0009617 200 0.015
positive regulation of nervous system development GO:0051962 178 0.015
regulation of metal ion transport GO:0010959 118 0.015
protein localization GO:0008104 191 0.015
developmental process involved in reproduction GO:0003006 159 0.015
anion transport GO:0006820 178 0.015
response to ethanol GO:0045471 162 0.015
negative regulation of molecular function GO:0044092 133 0.015
response to cytokine GO:0034097 215 0.015
regulation of hydrolase activity GO:0051336 143 0.015
defense response GO:0006952 194 0.015
axis specification GO:0009798 4 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
positive regulation of signal transduction GO:0009967 175 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
gamete generation GO:0007276 124 0.015
regeneration GO:0031099 163 0.015
ras protein signal transduction GO:0007265 29 0.015
positive regulation of secretion GO:0051047 140 0.015
response to ketone GO:1901654 182 0.015
anterior posterior pattern specification GO:0009952 1 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
calcium ion transport GO:0006816 131 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
divalent inorganic cation transport GO:0072511 134 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
regulation of anatomical structure size GO:0090066 135 0.015
positive regulation of secretion by cell GO:1903532 128 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
regulation of cellular component movement GO:0051270 150 0.014
nucleoside metabolic process GO:0009116 179 0.014
negative regulation of cell communication GO:0010648 158 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
response to carbohydrate GO:0009743 183 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
response to hexose GO:0009746 144 0.014
protein oligomerization GO:0051259 191 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
cation transmembrane transport GO:0098655 263 0.014
cell morphogenesis GO:0000902 142 0.014
inflammatory response GO:0006954 150 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
establishment of protein localization GO:0045184 141 0.014
proteolysis GO:0006508 175 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
regulation of synaptic transmission GO:0050804 141 0.013
reproductive structure development GO:0048608 128 0.013
peptidyl amino acid modification GO:0018193 126 0.013
regulation of cell motility GO:2000145 131 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
growth GO:0040007 165 0.013
mapk cascade GO:0000165 140 0.013
response to glucose GO:0009749 136 0.013
hormone secretion GO:0046879 115 0.013
hormone transport GO:0009914 121 0.013
cellular lipid metabolic process GO:0044255 208 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
negative regulation of transport GO:0051051 136 0.013
response to mechanical stimulus GO:0009612 134 0.013
regulation of cell migration GO:0030334 128 0.013
response to radiation GO:0009314 137 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
carbohydrate metabolic process GO:0005975 130 0.013
single organism organelle organization GO:1902589 180 0.013
response to reactive oxygen species GO:0000302 120 0.013
signal release GO:0023061 145 0.013
biological adhesion GO:0022610 110 0.013
cellular component morphogenesis GO:0032989 155 0.013
protein transport GO:0015031 132 0.012
heterocycle catabolic process GO:0046700 167 0.012
circulatory system development GO:0072359 134 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
cardiovascular system development GO:0072358 134 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
response to monosaccharide GO:0034284 159 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
cell projection morphogenesis GO:0048858 123 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
divalent metal ion transport GO:0070838 132 0.012
sex differentiation GO:0007548 113 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
dna metabolic process GO:0006259 96 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
embryonic skeletal system development GO:0048706 3 0.012
spermatogenesis GO:0007283 99 0.012
cellular response to external stimulus GO:0071496 118 0.012
regulation of cell growth GO:0001558 85 0.012
regulation of blood circulation GO:1903522 110 0.012
cytoplasmic transport GO:0016482 115 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
response to purine containing compound GO:0014074 126 0.012
axon development GO:0061564 96 0.012
reproductive system development GO:0061458 128 0.012
positive regulation of locomotion GO:0040017 102 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
regulation of immune system process GO:0002682 123 0.012
male gamete generation GO:0048232 99 0.012
eye morphogenesis GO:0048592 4 0.011
regulation of response to stress GO:0080134 126 0.011
regulation of homeostatic process GO:0032844 101 0.011
wound healing GO:0042060 122 0.011
organic anion transport GO:0015711 132 0.011
gastrulation GO:0007369 2 0.011
action potential GO:0001508 54 0.011
response to vitamin GO:0033273 131 0.011
regulation of kinase activity GO:0043549 117 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
multicellular organism growth GO:0035264 1 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
cell growth GO:0016049 104 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
epithelium development GO:0060429 96 0.011
sequestering of metal ion GO:0051238 9 0.011
response to alkaloid GO:0043279 132 0.011
regulation of growth GO:0040008 105 0.011
gonad development GO:0008406 104 0.011
sequestering of calcium ion GO:0051208 8 0.011
cell adhesion GO:0007155 110 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
lipid storage GO:0019915 1 0.011
embryonic pattern specification GO:0009880 1 0.011
regulation of protein kinase activity GO:0045859 105 0.011
gland development GO:0048732 155 0.011
response to retinoic acid GO:0032526 63 0.011
vesicle mediated transport GO:0016192 181 0.011
neuron death GO:0070997 127 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
immune response GO:0006955 104 0.011
regulation of membrane potential GO:0042391 110 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
maintenance of location GO:0051235 17 0.011
regulation of hormone secretion GO:0046883 106 0.011
response to toxic substance GO:0009636 133 0.011
response to organophosphorus GO:0046683 102 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
muscle system process GO:0003012 115 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
amide transport GO:0042886 105 0.011
regulation of catabolic process GO:0009894 113 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
response to insulin GO:0032868 133 0.011
cellular response to peptide GO:1901653 133 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
peptide transport GO:0015833 97 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
salivary gland development GO:0007431 3 0.010
regulation of peptide transport GO:0090087 87 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
negative regulation of innate immune response GO:0045824 4 0.010
sensory perception GO:0007600 101 0.010
organ regeneration GO:0031100 101 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
positive regulation of cell motility GO:2000147 97 0.010
embryonic skeletal system morphogenesis GO:0048704 3 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
gliogenesis GO:0042063 93 0.010
regulation of response to external stimulus GO:0032101 106 0.010
chemosensory behavior GO:0007635 2 0.010
female pregnancy GO:0007565 122 0.010
multi multicellular organism process GO:0044706 138 0.010
limb morphogenesis GO:0035108 4 0.010
regulation of organelle organization GO:0033043 80 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
regulation of mapk cascade GO:0043408 116 0.010
cell activation GO:0001775 97 0.010
appendage morphogenesis GO:0035107 4 0.010
negative regulation of catalytic activity GO:0043086 103 0.010

Lingo3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
musculoskeletal system disease DOID:17 0 0.013
disease of metabolism DOID:0014667 0 0.013
sensory system disease DOID:0050155 0 0.013
central nervous system disease DOID:331 0 0.012