Rattus norvegicus

27 known processes

Slc24a1

solute carrier family 24 (sodium/potassium/calcium exchanger), member 1

(Aliases: Nckx1)

Slc24a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transmembrane transport GO:0098655 263 0.297
g protein coupled receptor signaling pathway GO:0007186 242 0.175
inorganic cation transmembrane transport GO:0098662 202 0.168
regulation of cellular component organization GO:0051128 368 0.153
transmembrane transport GO:0055085 412 0.147
response to metal ion GO:0010038 253 0.133
inorganic ion transmembrane transport GO:0098660 229 0.113
divalent inorganic cation transport GO:0072511 134 0.109
regulation of heart contraction GO:0008016 48 0.098
response to cytokine GO:0034097 215 0.097
cytosolic calcium ion homeostasis GO:0051480 140 0.095
positive regulation of transport GO:0051050 245 0.095
circulatory system process GO:0003013 183 0.094
cellular cation homeostasis GO:0030003 180 0.093
metal ion transport GO:0030001 289 0.092
cellular divalent inorganic cation homeostasis GO:0072503 162 0.091
ion homeostasis GO:0050801 212 0.087
divalent inorganic cation homeostasis GO:0072507 165 0.084
regulation of phosphorus metabolic process GO:0051174 349 0.080
oxoacid metabolic process GO:0043436 290 0.079
homeostatic process GO:0042592 331 0.078
regulation of secretion GO:0051046 224 0.075
cellular metal ion homeostasis GO:0006875 172 0.074
cellular chemical homeostasis GO:0055082 247 0.070
regulation of ion transport GO:0043269 245 0.070
regulation of cellular component movement GO:0051270 150 0.069
cellular catabolic process GO:0044248 295 0.069
regulation of metal ion transport GO:0010959 118 0.067
small molecule biosynthetic process GO:0044283 124 0.062
negative regulation of transport GO:0051051 136 0.061
cation homeostasis GO:0055080 195 0.060
regulation of hydrolase activity GO:0051336 143 0.060
metal ion homeostasis GO:0055065 186 0.057
ion transmembrane transport GO:0034220 365 0.055
divalent metal ion transport GO:0070838 132 0.055
positive regulation of cellular component organization GO:0051130 200 0.053
detection of stimulus GO:0051606 24 0.053
blood circulation GO:0008015 183 0.053
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.051
regulation of blood pressure GO:0008217 83 0.051
secretion GO:0046903 307 0.049
sensory perception GO:0007600 101 0.048
protein complex subunit organization GO:0071822 302 0.048
response to histamine GO:0034776 3 0.047
regulation of cell proliferation GO:0042127 359 0.046
regulation of hormone secretion GO:0046883 106 0.045
cation transport GO:0006812 382 0.044
cellular homeostasis GO:0019725 252 0.044
regulation of cellular localization GO:0060341 263 0.043
nucleoside phosphate metabolic process GO:0006753 283 0.043
cellular ion homeostasis GO:0006873 184 0.042
regulation of peptide transport GO:0090087 87 0.042
negative regulation of multicellular organismal process GO:0051241 203 0.041
nitrogen compound transport GO:0071705 229 0.041
calcium ion homeostasis GO:0055074 162 0.041
neuron differentiation GO:0030182 368 0.041
neuron development GO:0048666 286 0.040
central nervous system development GO:0007417 311 0.039
carboxylic acid transport GO:0046942 115 0.039
insulin secretion GO:0030073 69 0.038
amide transport GO:0042886 105 0.038
negative regulation of developmental process GO:0051093 125 0.037
regulation of transmembrane transport GO:0034762 122 0.037
single organism intracellular transport GO:1902582 166 0.036
programmed cell death GO:0012501 392 0.036
response to extracellular stimulus GO:0009991 380 0.036
lipid metabolic process GO:0006629 283 0.036
single organism biosynthetic process GO:0044711 342 0.033
development of primary sexual characteristics GO:0045137 107 0.033
response to reactive oxygen species GO:0000302 120 0.032
response to decreased oxygen levels GO:0036293 237 0.032
positive regulation of biosynthetic process GO:0009891 319 0.032
cell cell signaling GO:0007267 335 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
organophosphate catabolic process GO:0046434 148 0.032
reproductive system development GO:0061458 128 0.032
aromatic compound catabolic process GO:0019439 168 0.031
response to radiation GO:0009314 137 0.031
chemical homeostasis GO:0048878 292 0.031
regulation of peptide hormone secretion GO:0090276 80 0.030
nucleoside phosphate catabolic process GO:1901292 140 0.030
brain development GO:0007420 247 0.030
development of primary female sexual characteristics GO:0046545 56 0.030
organic acid metabolic process GO:0006082 292 0.030
neuron projection development GO:0031175 273 0.030
response to glucocorticoid GO:0051384 223 0.030
response to inorganic substance GO:0010035 377 0.029
cell projection organization GO:0030030 302 0.029
response to oxygen levels GO:0070482 265 0.029
response to molecule of bacterial origin GO:0002237 194 0.029
positive regulation of signaling GO:0023056 270 0.029
detection of visible light GO:0009584 3 0.029
regulation of nervous system development GO:0051960 264 0.028
amine metabolic process GO:0009308 38 0.028
potassium ion transport GO:0006813 97 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
ribonucleotide metabolic process GO:0009259 231 0.028
phototransduction visible light GO:0007603 2 0.028
sensory organ development GO:0007423 74 0.027
calcium ion transport GO:0006816 131 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.026
response to hypoxia GO:0001666 231 0.026
single organism reproductive process GO:0044702 297 0.026
developmental process involved in reproduction GO:0003006 159 0.026
vesicle mediated transport GO:0016192 181 0.026
cellular response to stress GO:0033554 269 0.025
macromolecule localization GO:0033036 252 0.025
catabolic process GO:0009056 351 0.025
regulation of secretion by cell GO:1903530 208 0.025
sex differentiation GO:0007548 113 0.025
organic cyclic compound catabolic process GO:1901361 175 0.025
regulation of insulin secretion GO:0050796 65 0.024
peptide hormone secretion GO:0030072 84 0.024
cellular nitrogen compound catabolic process GO:0044270 163 0.024
response to organophosphorus GO:0046683 102 0.024
cellular ketone metabolic process GO:0042180 51 0.024
glycerolipid metabolic process GO:0046486 67 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
organic substance catabolic process GO:1901575 316 0.023
hormone transport GO:0009914 121 0.023
response to camp GO:0051591 91 0.023
nucleobase containing compound catabolic process GO:0034655 152 0.023
cellular response to external stimulus GO:0071496 118 0.023
peptide secretion GO:0002790 86 0.023
gonad development GO:0008406 104 0.023
defense response GO:0006952 194 0.023
eye development GO:0001654 50 0.023
regulation of anatomical structure size GO:0090066 135 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
camera type eye development GO:0043010 48 0.022
nucleotide catabolic process GO:0009166 139 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
organophosphate metabolic process GO:0019637 370 0.022
regulation of signal transduction GO:0009966 318 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
organic anion transport GO:0015711 132 0.021
positive regulation of cell communication GO:0010647 271 0.021
neurological system process GO:0050877 219 0.021
cell growth GO:0016049 104 0.021
secretion by cell GO:0032940 248 0.021
carboxylic acid metabolic process GO:0019752 289 0.021
protein complex assembly GO:0006461 263 0.021
aging GO:0007568 241 0.021
signal release GO:0023061 145 0.020
intracellular signal transduction GO:0035556 314 0.020
regulation of cell differentiation GO:0045595 320 0.020
regulation of calcium ion transport GO:0051924 77 0.020
regulation of hormone levels GO:0010817 187 0.020
cellular amine metabolic process GO:0044106 38 0.020
female gonad development GO:0008585 53 0.020
eye morphogenesis GO:0048592 4 0.020
cellular calcium ion homeostasis GO:0006874 160 0.020
reproductive process GO:0022414 372 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
cardiac muscle contraction GO:0060048 27 0.019
negative regulation of secretion GO:0051048 82 0.019
positive regulation of secretion by cell GO:1903532 128 0.019
protein complex biogenesis GO:0070271 263 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.019
negative regulation of signaling GO:0023057 157 0.019
monovalent inorganic cation transport GO:0015672 172 0.019
cellular component assembly GO:0022607 360 0.019
second messenger mediated signaling GO:0019932 51 0.019
heart process GO:0003015 57 0.018
peptidyl amino acid modification GO:0018193 126 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
regulation of catalytic activity GO:0050790 304 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
action potential GO:0001508 54 0.018
positive regulation of ion transport GO:0043270 94 0.018
multi organism reproductive process GO:0044703 262 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
organic acid biosynthetic process GO:0016053 83 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
purine nucleoside triphosphate catabolic process GO:0009146 122 0.017
positive regulation of nervous system development GO:0051962 178 0.017
cellular response to abiotic stimulus GO:0071214 85 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
regulation of cell development GO:0060284 263 0.017
sensory perception of pain GO:0019233 73 0.017
regulation of peptide secretion GO:0002791 82 0.017
nucleotide metabolic process GO:0009117 279 0.017
anion transmembrane transport GO:0098656 77 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.017
reproduction GO:0000003 245 0.017
regulation of system process GO:0044057 208 0.017
positive regulation of secretion GO:0051047 140 0.017
protein oligomerization GO:0051259 191 0.016
locomotion GO:0040011 237 0.016
response to oxidative stress GO:0006979 186 0.016
regulation of blood circulation GO:1903522 110 0.016
positive regulation of cell development GO:0010720 176 0.016
renal system development GO:0072001 67 0.016
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.016
reproductive structure development GO:0048608 128 0.016
regulation of ion transmembrane transport GO:0034765 121 0.016
male sex differentiation GO:0046661 64 0.016
head development GO:0060322 247 0.016
regulation of protein metabolic process GO:0051246 289 0.016
retina development in camera type eye GO:0060041 27 0.016
positive regulation of cell migration GO:0030335 96 0.015
nucleoside triphosphate catabolic process GO:0009143 123 0.015
organic hydroxy compound biosynthetic process GO:1901617 51 0.015
positive regulation of peptide secretion GO:0002793 52 0.015
response to bacterium GO:0009617 200 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
circulatory system development GO:0072359 134 0.015
lipid biosynthetic process GO:0008610 128 0.015
response to vitamin GO:0033273 131 0.015
cellular component movement GO:0006928 248 0.015
organelle organization GO:0006996 266 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
synapse organization GO:0050808 46 0.015
response to wounding GO:0009611 254 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
protein heterooligomerization GO:0051291 89 0.014
response to cgmp GO:0070305 3 0.014
regulation of ion transmembrane transporter activity GO:0032412 48 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
growth GO:0040007 165 0.014
purine containing compound catabolic process GO:0072523 138 0.014
alcohol metabolic process GO:0006066 77 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
proteolysis GO:0006508 175 0.014
cellular response to histamine GO:0071420 3 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
protein homooligomerization GO:0051260 91 0.014
response to peptide GO:1901652 292 0.014
peptide transport GO:0015833 97 0.014
negative regulation of metabolic process GO:0009892 331 0.014
regulation of molecular function GO:0065009 398 0.013
response to monosaccharide GO:0034284 159 0.013
female sex differentiation GO:0046660 59 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
cellular component biogenesis GO:0044085 368 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
positive regulation of gene expression GO:0010628 244 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
actin filament based process GO:0030029 86 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
regulation of multicellular organismal development GO:2000026 376 0.013
intracellular transport GO:0046907 185 0.013
single organism catabolic process GO:0044712 283 0.013
regulation of vesicle mediated transport GO:0060627 81 0.013
negative regulation of molecular function GO:0044092 133 0.013
transcription dna templated GO:0006351 377 0.013
negative regulation of cell death GO:0060548 229 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
negative regulation of hormone secretion GO:0046888 46 0.013
axis specification GO:0009798 4 0.013
response to interleukin 1 GO:0070555 55 0.013
regulation of locomotion GO:0040012 148 0.013
male gonad development GO:0008584 59 0.013
positive regulation of molecular function GO:0044093 230 0.012
response to mechanical stimulus GO:0009612 134 0.012
positive regulation of long term synaptic potentiation GO:1900273 4 0.012
response to alkaloid GO:0043279 132 0.012
negative regulation of signal transduction GO:0009968 83 0.012
negative regulation of intracellular signal transduction GO:1902532 38 0.012
sodium ion transport GO:0006814 82 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
localization of cell GO:0051674 202 0.012
negative regulation of blood pressure GO:0045776 29 0.012
single organism organelle organization GO:1902589 180 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.012
carbohydrate metabolic process GO:0005975 130 0.012
response to mineralocorticoid GO:0051385 49 0.012
response to acid chemical GO:0001101 222 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
exocytosis GO:0006887 60 0.012
calcium ion import GO:0070509 22 0.012
vascular process in circulatory system GO:0003018 96 0.012
negative regulation of cell communication GO:0010648 158 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
cellular response to lipid GO:0071396 201 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
negative regulation of response to stimulus GO:0048585 155 0.011
response to lipopolysaccharide GO:0032496 191 0.011
protein maturation GO:0051604 68 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
positive regulation of cell motility GO:2000147 97 0.011
cell migration GO:0016477 197 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
synaptic transmission GO:0007268 235 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
regulation of response to external stimulus GO:0032101 106 0.011
regulation of behavior GO:0050795 61 0.011
response to nicotine GO:0035094 51 0.011
response to nutrient levels GO:0031667 370 0.011
response to temperature stimulus GO:0009266 94 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
response to light stimulus GO:0009416 52 0.011
sensory perception of bitter taste GO:0050913 4 0.011
development of primary male sexual characteristics GO:0046546 59 0.011
detection of external stimulus GO:0009581 13 0.011
detection of temperature stimulus involved in sensory perception of pain GO:0050965 4 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
regulation of nucleoside metabolic process GO:0009118 66 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
ovulation cycle GO:0042698 67 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
apoptotic process GO:0006915 381 0.011
cellular response to alcohol GO:0097306 87 0.011
steroid metabolic process GO:0008202 73 0.010
response to external biotic stimulus GO:0043207 221 0.010
regulation of apoptotic process GO:0042981 335 0.010
regulation of phosphorylation GO:0042325 248 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
positive regulation of insulin secretion GO:0032024 36 0.010
lipid modification GO:0030258 52 0.010
detection of temperature stimulus GO:0016048 4 0.010
regulation of synaptic transmission GO:0050804 141 0.010
membrane organization GO:0061024 94 0.010
vasodilation GO:0042311 44 0.010
protein processing GO:0016485 68 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
cytoskeleton organization GO:0007010 111 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
sexual reproduction GO:0019953 148 0.010
response to hydrogen peroxide GO:0042542 89 0.010

Slc24a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.966
retinal degeneration DOID:8466 0 0.966
sensory system disease DOID:0050155 0 0.966
disease of anatomical entity DOID:7 0 0.966
retinitis pigmentosa DOID:10584 0 0.966
eye and adnexa disease DOID:1492 0 0.966
nervous system disease DOID:863 0 0.966
eye disease DOID:5614 0 0.966
night blindness DOID:8499 0 0.258
cardiovascular system disease DOID:1287 0 0.028
cone rod dystrophy DOID:0050572 0 0.012