Rattus norvegicus

0 known processes

Card6

caspase recruitment domain family, member 6

Card6 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.055
oxoacid metabolic process GO:0043436 290 0.048
catabolic process GO:0009056 351 0.048
cellular amino acid metabolic process GO:0006520 107 0.044
response to inorganic substance GO:0010035 377 0.034
amine metabolic process GO:0009308 38 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.033
neuron differentiation GO:0030182 368 0.033
cellular amine metabolic process GO:0044106 38 0.032
protein complex biogenesis GO:0070271 263 0.032
carboxylic acid metabolic process GO:0019752 289 0.031
macromolecular complex assembly GO:0065003 273 0.031
cellular catabolic process GO:0044248 295 0.030
regulation of multicellular organismal development GO:2000026 376 0.030
single organism biosynthetic process GO:0044711 342 0.030
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.030
protein complex subunit organization GO:0071822 302 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
organophosphate metabolic process GO:0019637 370 0.029
cell projection organization GO:0030030 302 0.029
negative regulation of innate immune response GO:0045824 4 0.028
cellular component biogenesis GO:0044085 368 0.028
cellular ketone metabolic process GO:0042180 51 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.027
neuron projection development GO:0031175 273 0.027
single organism catabolic process GO:0044712 283 0.027
macromolecular complex subunit organization GO:0043933 339 0.026
protein oligomerization GO:0051259 191 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
response to nutrient levels GO:0031667 370 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.025
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.025
organic substance catabolic process GO:1901575 316 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
cellular component assembly GO:0022607 360 0.025
response to metal ion GO:0010038 253 0.025
nucleotide metabolic process GO:0009117 279 0.025
homeostatic process GO:0042592 331 0.024
immune system process GO:0002376 204 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
regulation of cellular component organization GO:0051128 368 0.023
regulation of molecular function GO:0065009 398 0.023
regulation of cell development GO:0060284 263 0.023
protein complex assembly GO:0006461 263 0.022
response to cytokine GO:0034097 215 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
nucleoside metabolic process GO:0009116 179 0.022
cellular response to stress GO:0033554 269 0.022
regulation of cell differentiation GO:0045595 320 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
regulation of neurogenesis GO:0050767 247 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
response to extracellular stimulus GO:0009991 380 0.021
organelle organization GO:0006996 266 0.021
response to wounding GO:0009611 254 0.021
localization of cell GO:0051674 202 0.021
rna metabolic process GO:0016070 406 0.021
regulation of nervous system development GO:0051960 264 0.021
purine containing compound metabolic process GO:0072521 253 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
ribose phosphate metabolic process GO:0019693 235 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
purine ribonucleotide catabolic process GO:0009154 136 0.020
immune response GO:0006955 104 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
central nervous system development GO:0007417 311 0.020
regulation of signal transduction GO:0009966 318 0.020
regulation of protein metabolic process GO:0051246 289 0.020
regulation of phosphate metabolic process GO:0019220 349 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
cellular component movement GO:0006928 248 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
ion transmembrane transport GO:0034220 365 0.020
purine nucleotide metabolic process GO:0006163 229 0.019
intracellular signal transduction GO:0035556 314 0.019
protein phosphorylation GO:0006468 345 0.019
positive regulation of molecular function GO:0044093 230 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
response to acid chemical GO:0001101 222 0.019
ion homeostasis GO:0050801 212 0.019
regulation of cell projection organization GO:0031344 175 0.019
cell motility GO:0048870 202 0.019
positive regulation of cell development GO:0010720 176 0.019
response to ethanol GO:0045471 162 0.019
defense response GO:0006952 194 0.019
positive regulation of developmental process GO:0051094 283 0.019
transmembrane transport GO:0055085 412 0.019
aromatic compound catabolic process GO:0019439 168 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
ras protein signal transduction GO:0007265 29 0.018
cell migration GO:0016477 197 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
multi organism reproductive process GO:0044703 262 0.018
regulation of catalytic activity GO:0050790 304 0.018
reproductive process GO:0022414 372 0.018
organophosphate catabolic process GO:0046434 148 0.018
response to peptide hormone GO:0043434 278 0.018
response to growth factor GO:0070848 189 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
neuron development GO:0048666 286 0.018
regulation of neuron projection development GO:0010975 161 0.018
secretion GO:0046903 307 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
positive regulation of gene expression GO:0010628 244 0.017
heterocycle catabolic process GO:0046700 167 0.017
regulation of neuron differentiation GO:0045664 208 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
cation transmembrane transport GO:0098655 263 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
inorganic ion transmembrane transport GO:0098660 229 0.017
cell adhesion GO:0007155 110 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
response to toxic substance GO:0009636 133 0.017
reproduction GO:0000003 245 0.017
regulation of cell proliferation GO:0042127 359 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
single organism organelle organization GO:1902589 180 0.017
regulation of rna metabolic process GO:0051252 391 0.017
macromolecule localization GO:0033036 252 0.017
regulation of membrane potential GO:0042391 110 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
nucleoside catabolic process GO:0009164 126 0.017
cellular lipid metabolic process GO:0044255 208 0.017
cation transport GO:0006812 382 0.017
multicellular organism reproduction GO:0032504 233 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
single organism intracellular transport GO:1902582 166 0.017
negative regulation of metabolic process GO:0009892 331 0.016
single organism reproductive process GO:0044702 297 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
programmed cell death GO:0012501 392 0.016
response to nutrient GO:0007584 248 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
response to oxidative stress GO:0006979 186 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
response to biotic stimulus GO:0009607 226 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
negative regulation of cell death GO:0060548 229 0.016
regulation of cell motility GO:2000145 131 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
regulation of apoptotic process GO:0042981 335 0.016
purine containing compound catabolic process GO:0072523 138 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
regulation of programmed cell death GO:0043067 341 0.016
response to estrogen GO:0043627 232 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
spindle organization GO:0007051 2 0.015
response to external biotic stimulus GO:0043207 221 0.015
response to other organism GO:0051707 220 0.015
chemical homeostasis GO:0048878 292 0.015
glycosyl compound catabolic process GO:1901658 126 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
regulation of locomotion GO:0040012 148 0.015
response to hypoxia GO:0001666 231 0.015
rna biosynthetic process GO:0032774 380 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
nucleotide catabolic process GO:0009166 139 0.015
response to peptide GO:1901652 292 0.015
transcription dna templated GO:0006351 377 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
apoptotic process GO:0006915 381 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
positive regulation of nervous system development GO:0051962 178 0.015
regulation of cell migration GO:0030334 128 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
cation homeostasis GO:0055080 195 0.015
ribonucleotide catabolic process GO:0009261 136 0.015
response to vitamin GO:0033273 131 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
response to corticosteroid GO:0031960 235 0.014
head development GO:0060322 247 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
positive regulation of signaling GO:0023056 270 0.014
regulation of transcription dna templated GO:0006355 374 0.014
chromosome segregation GO:0007059 2 0.014
regulation of nucleic acid templated transcription GO:1903506 380 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
negative regulation of developmental process GO:0051093 125 0.014
response to decreased oxygen levels GO:0036293 237 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
response to reactive oxygen species GO:0000302 120 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
nucleic acid templated transcription GO:0097659 379 0.014
nucleoside triphosphate catabolic process GO:0009143 123 0.014
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.014
circulatory system process GO:0003013 183 0.014
potassium ion transport GO:0006813 97 0.014
metal ion homeostasis GO:0055065 186 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
metal ion transport GO:0030001 289 0.014
cellular chemical homeostasis GO:0055082 247 0.014
axis specification GO:0009798 4 0.014
leukocyte cell cell adhesion GO:0007159 4 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
cellular homeostasis GO:0019725 252 0.013
oxidation reduction process GO:0055114 304 0.013
locomotion GO:0040011 237 0.013
gliogenesis GO:0042063 93 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
response to oxygen levels GO:0070482 265 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
intracellular transport GO:0046907 185 0.013
cellular response to oxidative stress GO:0034599 76 0.013
biological adhesion GO:0022610 110 0.013
regulation of cellular component movement GO:0051270 150 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
regulation of phosphorylation GO:0042325 248 0.013
growth GO:0040007 165 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
cellular cation homeostasis GO:0030003 180 0.013
gamete generation GO:0007276 124 0.013
anterior posterior pattern specification GO:0009952 1 0.013
regulation of cellular localization GO:0060341 263 0.013
positive regulation of cell death GO:0010942 184 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
neuron death GO:0070997 127 0.012
regulation of protein modification process GO:0031399 194 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
regeneration GO:0031099 163 0.012
protein heterooligomerization GO:0051291 89 0.012
anion transport GO:0006820 178 0.012
regulation of transferase activity GO:0051338 123 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
cellular response to external stimulus GO:0071496 118 0.012
peptidyl amino acid modification GO:0018193 126 0.012
aging GO:0007568 241 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
regulation of immune system process GO:0002682 123 0.012
response to bacterium GO:0009617 200 0.012
cytoskeleton organization GO:0007010 111 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
response to tumor cell GO:0002347 4 0.012
sexual reproduction GO:0019953 148 0.012
dephosphorylation GO:0016311 98 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
positive regulation of protein modification process GO:0031401 142 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
regulation of immune response to tumor cell GO:0002837 3 0.012
regulation of system process GO:0044057 208 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
regulation of secretion by cell GO:1903530 208 0.012
cell cell signaling GO:0007267 335 0.012
positive regulation of cell communication GO:0010647 271 0.012
cellular ion homeostasis GO:0006873 184 0.012
secretion by cell GO:0032940 248 0.012
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.012
negative regulation of cell communication GO:0010648 158 0.012
cellular response to lipid GO:0071396 201 0.012
lipid metabolic process GO:0006629 283 0.012
response to purine containing compound GO:0014074 126 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
carbohydrate metabolic process GO:0005975 130 0.012
brain development GO:0007420 247 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
eye morphogenesis GO:0048592 4 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
regulation of hormone levels GO:0010817 187 0.011
innate immune response GO:0045087 35 0.011
meiotic cell cycle process GO:1903046 3 0.011
gland development GO:0048732 155 0.011
regulation of cytokine biosynthetic process GO:0042035 3 0.011
salivary gland development GO:0007431 3 0.011
response to carbohydrate GO:0009743 183 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
immune response to tumor cell GO:0002418 3 0.011
establishment of protein localization GO:0045184 141 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
regulation of anatomical structure size GO:0090066 135 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
vesicle mediated transport GO:0016192 181 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
negative regulation of signaling GO:0023057 157 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
regulation of hydrolase activity GO:0051336 143 0.011
hepaticobiliary system development GO:0061008 90 0.011
proteolysis GO:0006508 175 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
negative regulation of response to tumor cell GO:0002835 2 0.011
regulation of neuron death GO:1901214 115 0.011
protein localization GO:0008104 191 0.011
negative regulation of immune response to tumor cell GO:0002838 2 0.011
regulation of defense response GO:0031347 68 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
lipid storage GO:0019915 1 0.011
regulation of response to stress GO:0080134 126 0.011
antigen receptor mediated signaling pathway GO:0050851 1 0.011
response to alkaloid GO:0043279 132 0.011
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.011
dna metabolic process GO:0006259 96 0.010
response to organophosphorus GO:0046683 102 0.010
positive regulation of signal transduction GO:0009967 175 0.010
rho protein signal transduction GO:0007266 11 0.010
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.010
organ regeneration GO:0031100 101 0.010
positive regulation of transport GO:0051050 245 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
ncrna processing GO:0034470 3 0.010
nitrogen compound transport GO:0071705 229 0.010
response to ketone GO:1901654 182 0.010
calcium ion homeostasis GO:0055074 162 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
double strand break repair GO:0006302 1 0.010
response to estradiol GO:0032355 164 0.010
cytoplasmic transport GO:0016482 115 0.010
circulatory system development GO:0072359 134 0.010
regulation of cellular catabolic process GO:0031329 101 0.010
cardiovascular system development GO:0072358 134 0.010
hormone secretion GO:0046879 115 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.010
regulation of secretion GO:0051046 224 0.010
tissue development GO:0009888 252 0.010
negative regulation of transport GO:0051051 136 0.010
blood circulation GO:0008015 183 0.010
wound healing GO:0042060 122 0.010
gtp metabolic process GO:0046039 72 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
small molecule biosynthetic process GO:0044283 124 0.010

Card6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
musculoskeletal system disease DOID:17 0 0.012
disease of metabolism DOID:0014667 0 0.011
central nervous system disease DOID:331 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010