|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.572
|
Rat |
|
|
neuron development
|
GO:0048666 |
286 |
0.557
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.550
|
|
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.485
|
|
|
|
cellular component movement
|
GO:0006928 |
248 |
0.472
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.396
|
|
|
|
cell cell signaling
|
GO:0007267 |
335 |
0.378
|
|
|
|
regulation of ion transport
|
GO:0043269 |
245 |
0.376
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.372
|
Rat |
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.352
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
208 |
0.333
|
|
|
|
circulatory system development
|
GO:0072359 |
134 |
0.326
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.310
|
Rat |
|
|
developmental process involved in reproduction
|
GO:0003006 |
159 |
0.306
|
Worm |
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.303
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
51 |
0.303
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.298
|
Rat |
|
|
neuron projection development
|
GO:0031175 |
273 |
0.275
|
|
|
|
potassium ion transport
|
GO:0006813 |
97 |
0.270
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.266
|
Rat |
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.264
|
Rat |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.257
|
|
|
|
catecholamine secretion
|
GO:0050432 |
33 |
0.255
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
48 |
0.252
|
|
|
|
female mating behavior
|
GO:0060180 |
6 |
0.248
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
51 |
0.245
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.238
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
66 |
0.236
|
|
|
|
cell motility
|
GO:0048870 |
202 |
0.231
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
50 |
0.231
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
123 |
0.231
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.230
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
202 |
0.225
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.221
|
|
|
|
programmed cell death
|
GO:0012501 |
392 |
0.219
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.218
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.217
|
Fly |
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.212
|
Worm |
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.212
|
Rat |
|
|
ion transmembrane transport
|
GO:0034220 |
365 |
0.209
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.206
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.203
|
Rat Fly |
|
|
regulation of blood vessel size
|
GO:0050880 |
89 |
0.198
|
|
|
|
g protein coupled purinergic receptor signaling pathway
|
GO:0035588 |
8 |
0.197
|
|
|
|
amine transport
|
GO:0015837 |
57 |
0.195
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.192
|
|
|
|
cation transport
|
GO:0006812 |
382 |
0.191
|
|
|
|
camp metabolic process
|
GO:0046058 |
63 |
0.190
|
|
|
|
regulation of system process
|
GO:0044057 |
208 |
0.189
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
263 |
0.180
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
71 |
0.178
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
110 |
0.177
|
|
|
|
heart development
|
GO:0007507 |
72 |
0.176
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
247 |
0.175
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.171
|
|
|
|
positive regulation of amine transport
|
GO:0051954 |
26 |
0.170
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.166
|
|
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.164
|
Rat |
|
|
regulation of anatomical structure size
|
GO:0090066 |
135 |
0.164
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
19 |
0.162
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.162
|
|
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.161
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
271 |
0.161
|
Fly |
|
|
single organism membrane organization
|
GO:0044802 |
74 |
0.158
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.157
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.153
|
|
|
|
digestive system development
|
GO:0055123 |
41 |
0.151
|
|
|
|
reproductive system development
|
GO:0061458 |
128 |
0.148
|
Worm |
|
|
axonogenesis
|
GO:0007409 |
71 |
0.144
|
|
|
|
neurological system process
|
GO:0050877 |
219 |
0.143
|
|
|
|
cell migration
|
GO:0016477 |
197 |
0.142
|
|
|
|
locomotion
|
GO:0040011 |
237 |
0.142
|
Worm Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.141
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
48 |
0.140
|
Fly |
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.138
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
49 |
0.138
|
|
|
|
regulation of catecholamine secretion
|
GO:0050433 |
32 |
0.136
|
|
|
|
regulation of synaptic transmission gabaergic
|
GO:0032228 |
17 |
0.135
|
|
|
|
metal ion transport
|
GO:0030001 |
289 |
0.135
|
|
|
|
cellular homeostasis
|
GO:0019725 |
252 |
0.133
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.132
|
Fly |
|
|
norepinephrine secretion
|
GO:0048243 |
16 |
0.124
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.124
|
|
|
|
digestive tract development
|
GO:0048565 |
39 |
0.123
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.121
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
119 |
0.121
|
Human |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.120
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
106 |
0.120
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.120
|
|
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
4 |
0.119
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.119
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.117
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.116
|
|
|
|
action potential
|
GO:0001508 |
54 |
0.113
|
|
|
|
dendrite development
|
GO:0016358 |
72 |
0.112
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
186 |
0.108
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.107
|
|
|
|
regulation of cell growth
|
GO:0001558 |
85 |
0.105
|
|
|
|
negative regulation of muscle cell apoptotic process
|
GO:0010656 |
21 |
0.105
|
|
|
|
cation homeostasis
|
GO:0055080 |
195 |
0.105
|
|
|
|
secretion by cell
|
GO:0032940 |
248 |
0.104
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.104
|
Fly |
|
|
gastrulation
|
GO:0007369 |
2 |
0.103
|
|
|
|
negative regulation of transporter activity
|
GO:0032410 |
13 |
0.103
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
160 |
0.102
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.102
|
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.102
|
Fly |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
106 |
0.102
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.100
|
|
|
|
reproductive structure development
|
GO:0048608 |
128 |
0.100
|
Worm |
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.097
|
|
|
|
regulation of tube size
|
GO:0035150 |
89 |
0.097
|
|
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.097
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
12 |
0.096
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
187 |
0.096
|
|
|
|
response to ketone
|
GO:1901654 |
182 |
0.094
|
|
|
|
catecholamine transport
|
GO:0051937 |
37 |
0.094
|
|
|
|
sensory perception of pain
|
GO:0019233 |
73 |
0.093
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.093
|
|
|
|
ion homeostasis
|
GO:0050801 |
212 |
0.093
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
1 |
0.093
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
37 |
0.093
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
91 |
0.092
|
|
|
|
negative regulation of transport
|
GO:0051051 |
136 |
0.092
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
172 |
0.092
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
29 |
0.091
|
Fly |
|
|
development of primary sexual characteristics
|
GO:0045137 |
107 |
0.090
|
Worm |
|
|
regulation of amine transport
|
GO:0051952 |
54 |
0.090
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.089
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.089
|
|
|
|
tube development
|
GO:0035295 |
89 |
0.089
|
|
|
|
regulation of cardiac muscle cell contraction
|
GO:0086004 |
11 |
0.088
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
162 |
0.088
|
|
|
|
negative regulation of cardiac muscle tissue development
|
GO:0055026 |
3 |
0.088
|
|
|
|
maintenance of location
|
GO:0051235 |
17 |
0.087
|
|
|
|
synaptic transmission
|
GO:0007268 |
235 |
0.087
|
|
|
|
mesoderm development
|
GO:0007498 |
2 |
0.086
|
|
|
|
localization of cell
|
GO:0051674 |
202 |
0.086
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.085
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.085
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.085
|
Fly |
|
|
homeostatic process
|
GO:0042592 |
331 |
0.084
|
|
|
|
protein localization to membrane
|
GO:0072657 |
36 |
0.084
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
42 |
0.082
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
62 |
0.082
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
162 |
0.081
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
53 |
0.081
|
|
|
|
behavior
|
GO:0007610 |
205 |
0.081
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.081
|
|
|
|
cardiovascular system development
|
GO:0072358 |
134 |
0.081
|
|
|
|
chemical homeostasis
|
GO:0048878 |
292 |
0.081
|
|
|
|
circulatory system process
|
GO:0003013 |
183 |
0.081
|
|
|
|
brain development
|
GO:0007420 |
247 |
0.081
|
|
|
|
regulation of inhibitory postsynaptic membrane potential
|
GO:0060080 |
6 |
0.080
|
|
|
|
positive regulation of acetylcholine secretion neurotransmission
|
GO:0014057 |
3 |
0.080
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
122 |
0.079
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.079
|
|
|
|
hormone secretion
|
GO:0046879 |
115 |
0.079
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
118 |
0.078
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.078
|
|
|
|
muscle structure development
|
GO:0061061 |
87 |
0.078
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
180 |
0.076
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.074
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
90 |
0.072
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.071
|
|
|
|
regulation of muscle cell apoptotic process
|
GO:0010660 |
26 |
0.071
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
48 |
0.070
|
Fly |
|
|
reproductive process
|
GO:0022414 |
372 |
0.070
|
Worm |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
316 |
0.070
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
143 |
0.069
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.069
|
|
|
|
regulation of locomotion
|
GO:0040012 |
148 |
0.068
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
113 |
0.068
|
|
|
|
cell growth
|
GO:0016049 |
104 |
0.068
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
10 |
0.067
|
|
|
|
membrane organization
|
GO:0061024 |
94 |
0.067
|
|
|
|
organelle organization
|
GO:0006996 |
266 |
0.067
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
77 |
0.067
|
|
|
|
male mating behavior
|
GO:0060179 |
3 |
0.066
|
|
|
|
renin secretion into blood stream
|
GO:0002001 |
1 |
0.066
|
|
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.066
|
|
|
|
sex differentiation
|
GO:0007548 |
113 |
0.065
|
Worm |
|
|
gliogenesis
|
GO:0042063 |
93 |
0.065
|
|
|
|
forebrain development
|
GO:0030900 |
98 |
0.065
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
94 |
0.064
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.064
|
Rat |
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.064
|
Rat |
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.063
|
|
|
|
regulation of cation channel activity
|
GO:2001257 |
23 |
0.062
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
136 |
0.061
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.061
|
Worm |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
165 |
0.061
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.061
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.061
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.060
|
Fly |
|
|
macromolecular complex subunit organization
|
GO:0043933 |
339 |
0.059
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
63 |
0.059
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.059
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
116 |
0.059
|
|
|
|
secretion
|
GO:0046903 |
307 |
0.058
|
|
|
|
response to light stimulus
|
GO:0009416 |
52 |
0.058
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
38 |
0.058
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
126 |
0.058
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
96 |
0.058
|
|
|
|
cell cycle
|
GO:0007049 |
101 |
0.057
|
Fly |
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
153 |
0.057
|
Rat |
|
|
telencephalon development
|
GO:0021537 |
62 |
0.057
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
65 |
0.056
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
110 |
0.056
|
|
|
|
response to wounding
|
GO:0009611 |
254 |
0.056
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
27 |
0.056
|
|
|
|
single organism catabolic process
|
GO:0044712 |
283 |
0.056
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
68 |
0.055
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
124 |
0.055
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
184 |
0.055
|
|
|
|
regulation of synaptic transmission glutamatergic
|
GO:0051966 |
26 |
0.055
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
22 |
0.055
|
|
|
|
astrocyte development
|
GO:0014002 |
4 |
0.055
|
|
|
|
striated muscle contraction
|
GO:0006941 |
44 |
0.054
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
242 |
0.054
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
4 |
0.054
|
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.054
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
69 |
0.053
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
2 |
0.053
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
75 |
0.053
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
122 |
0.053
|
|
|
|
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
|
GO:0010880 |
4 |
0.053
|
|
|
|
mesoderm formation
|
GO:0001707 |
1 |
0.053
|
|
|
|
single organism organelle organization
|
GO:1902589 |
180 |
0.053
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
80 |
0.053
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
121 |
0.052
|
|
|
|
maintenance of protein location
|
GO:0045185 |
7 |
0.052
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
73 |
0.052
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.051
|
Rat |
|
|
rhythmic process
|
GO:0048511 |
156 |
0.051
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
1 |
0.051
|
|
|
|
mesonephros development
|
GO:0001823 |
14 |
0.051
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
29 |
0.051
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.051
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.051
|
|
|
|
biological adhesion
|
GO:0022610 |
110 |
0.051
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.050
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
79 |
0.050
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.050
|
Fly |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.050
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
53 |
0.049
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.049
|
Fly |
|
|
heterocycle catabolic process
|
GO:0046700 |
167 |
0.049
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
1 |
0.049
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
208 |
0.048
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
229 |
0.048
|
|
|
|
circadian rhythm
|
GO:0007623 |
88 |
0.048
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.048
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
45 |
0.047
|
|
|
|
monoamine transport
|
GO:0015844 |
43 |
0.047
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.047
|
Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.047
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
86 |
0.047
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
200 |
0.046
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.046
|
|
|
|
response to radiation
|
GO:0009314 |
137 |
0.046
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
124 |
0.046
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.046
|
Fly |
|
|
head development
|
GO:0060322 |
247 |
0.046
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
83 |
0.046
|
|
|
|
response to growth factor
|
GO:0070848 |
189 |
0.045
|
|
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.045
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
25 |
0.045
|
|
|
|
heart morphogenesis
|
GO:0003007 |
3 |
0.045
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
14 |
0.045
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.045
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
115 |
0.045
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
73 |
0.045
|
Fly |
|
|
regulation of amino acid transport
|
GO:0051955 |
25 |
0.044
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
175 |
0.044
|
|
|
|
purinergic receptor signaling pathway
|
GO:0035587 |
10 |
0.044
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.044
|
|
|
|
tissue development
|
GO:0009888 |
252 |
0.044
|
Fly |
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.044
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.044
|
|
|
|
positive regulation of catecholamine secretion
|
GO:0033605 |
13 |
0.043
|
|
|
|
response to alkaloid
|
GO:0043279 |
132 |
0.043
|
|
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.043
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
175 |
0.043
|
|
|
|
heart contraction
|
GO:0060047 |
57 |
0.043
|
|
|
|
olfactory behavior
|
GO:0042048 |
2 |
0.043
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001241 |
2 |
0.043
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.042
|
|
|
|
axon development
|
GO:0061564 |
96 |
0.042
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
82 |
0.042
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
65 |
0.042
|
|
|
|
synaptic transmission glutamatergic
|
GO:0035249 |
33 |
0.042
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
77 |
0.042
|
|
|
|
muscle contraction
|
GO:0006936 |
88 |
0.042
|
|
|
|
regulation of respiratory system process
|
GO:0044065 |
1 |
0.042
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.042
|
Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
115 |
0.042
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
45 |
0.041
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
25 |
0.041
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.041
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
79 |
0.041
|
|
|
|
gonad development
|
GO:0008406 |
104 |
0.041
|
Worm |
|
|
positive regulation of secretion
|
GO:0051047 |
140 |
0.041
|
|
|
|
negative regulation of circadian sleep wake cycle non rem sleep
|
GO:0042323 |
2 |
0.041
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.041
|
|
|
|
astrocyte activation
|
GO:0048143 |
4 |
0.040
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
18 |
0.040
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
161 |
0.040
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
122 |
0.040
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
83 |
0.040
|
|
|
|
negative regulation of potassium ion transport
|
GO:0043267 |
11 |
0.040
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
167 |
0.040
|
|
|
|
neuromuscular process
|
GO:0050905 |
2 |
0.040
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.040
|
|
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.039
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
139 |
0.039
|
|
|
|
actin filament based process
|
GO:0030029 |
86 |
0.039
|
|
|
|
grooming behavior
|
GO:0007625 |
4 |
0.039
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.039
|
Rat |
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.039
|
Fly |
|
|
cellular potassium ion transport
|
GO:0071804 |
72 |
0.039
|
|
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
17 |
0.039
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
135 |
0.039
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
78 |
0.039
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.039
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.039
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
48 |
0.038
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
37 |
0.038
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.038
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
102 |
0.038
|
|
|
|
glial cell differentiation
|
GO:0010001 |
65 |
0.038
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
208 |
0.038
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.038
|
Human |
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.038
|
Rat |
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
17 |
0.038
|
|
|
|
sympathetic nervous system development
|
GO:0048485 |
1 |
0.037
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
119 |
0.037
|
|
|
|
aging
|
GO:0007568 |
241 |
0.037
|
|
|
|
growth
|
GO:0040007 |
165 |
0.037
|
|
|
|
regulation of organ growth
|
GO:0046620 |
13 |
0.037
|
|
|
|
negative regulation of osteoblast differentiation
|
GO:0045668 |
2 |
0.037
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
51 |
0.037
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
117 |
0.037
|
|
|
|
regulation of renin secretion into blood stream
|
GO:1900133 |
1 |
0.037
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.037
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.037
|
|
|
|
positive regulation of long term synaptic potentiation
|
GO:1900273 |
4 |
0.037
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
302 |
0.037
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
65 |
0.036
|
|
|
|
actin filament based movement
|
GO:0030048 |
16 |
0.036
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.036
|
|
|
|
hormone transport
|
GO:0009914 |
121 |
0.036
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
316 |
0.036
|
|
|
|
synapse organization
|
GO:0050808 |
46 |
0.036
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
1 |
0.036
|
|
|
|
muscle tissue development
|
GO:0060537 |
58 |
0.036
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.036
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
8 |
0.035
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
82 |
0.035
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
3 |
0.035
|
|
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.035
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
107 |
0.035
|
|
|
|
sensory perception
|
GO:0007600 |
101 |
0.035
|
|
|
|
male sex differentiation
|
GO:0046661 |
64 |
0.035
|
|
|
|
neural crest cell development
|
GO:0014032 |
2 |
0.035
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.035
|
Fly |
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.034
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.034
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
28 |
0.034
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.034
|
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
51 |
0.034
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.034
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
140 |
0.034
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
101 |
0.034
|
|
|
|
regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway
|
GO:0010578 |
2 |
0.034
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
162 |
0.033
|
|
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.033
|
Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
148 |
0.033
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
31 |
0.033
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.033
|
|
|
|
regulation of heart growth
|
GO:0060420 |
12 |
0.033
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
138 |
0.033
|
|
|
|
epithelium development
|
GO:0060429 |
96 |
0.033
|
Fly |
|
|
muscle cell apoptotic process
|
GO:0010657 |
30 |
0.033
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.033
|
|
|
|
protein localization
|
GO:0008104 |
191 |
0.032
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
101 |
0.032
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
43 |
0.032
|
|
|
|
positive regulation of renin secretion into blood stream
|
GO:1900135 |
1 |
0.032
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.032
|
|
|
|
tangential migration from the subventricular zone to the olfactory bulb
|
GO:0022028 |
1 |
0.032
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
52 |
0.032
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
165 |
0.032
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
128 |
0.032
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
45 |
0.032
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
31 |
0.031
|
|
|
|
chemotaxis
|
GO:0006935 |
66 |
0.031
|
|
|
|
signal release
|
GO:0023061 |
145 |
0.031
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
55 |
0.031
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
72 |
0.031
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
14 |
0.031
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
141 |
0.031
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
78 |
0.031
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
140 |
0.031
|
|
|
|
gland development
|
GO:0048732 |
155 |
0.030
|
|
|
|
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway
|
GO:0010579 |
2 |
0.030
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
71 |
0.030
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
26 |
0.030
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
138 |
0.030
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
84 |
0.030
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.030
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.030
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.030
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
81 |
0.030
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
229 |
0.030
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.030
|
Rat |
|
|
respiratory gaseous exchange
|
GO:0007585 |
4 |
0.030
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
99 |
0.030
|
|
|
|
neuron projection guidance
|
GO:0097485 |
24 |
0.029
|
|
|
|
regulation of cell migration
|
GO:0030334 |
128 |
0.029
|
|
|
|
negative regulation of ion transmembrane transporter activity
|
GO:0032413 |
12 |
0.029
|
|
|
|
positive regulation of synaptic vesicle exocytosis
|
GO:2000302 |
3 |
0.029
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.029
|
Rat |
|
|
learning or memory
|
GO:0007611 |
90 |
0.029
|
|
|
|
muscle organ development
|
GO:0007517 |
50 |
0.029
|
|
|
|
peptide secretion
|
GO:0002790 |
86 |
0.029
|
|
|
|
protein complex assembly
|
GO:0006461 |
263 |
0.029
|
|
|
|
axis specification
|
GO:0009798 |
4 |
0.029
|
|
|
|
response to hypoxia
|
GO:0001666 |
231 |
0.028
|
|
|
|
regulation of cell motility
|
GO:2000145 |
131 |
0.028
|
|
|
|
regulation of neurological system process
|
GO:0031644 |
43 |
0.028
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
45 |
0.028
|
Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
141 |
0.028
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
141 |
0.028
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
138 |
0.028
|
Fly |
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.028
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.028
|
Rat |
|
|
regulation of norepinephrine secretion
|
GO:0014061 |
15 |
0.028
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
82 |
0.027
|
|
|
|
autonomic nervous system development
|
GO:0048483 |
3 |
0.027
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
237 |
0.027
|
|
|
|
mapk cascade
|
GO:0000165 |
140 |
0.027
|
Fly |
|
|
anterior posterior pattern specification
|
GO:0009952 |
1 |
0.027
|
|
|
|
vasodilation
|
GO:0042311 |
44 |
0.027
|
|
|
|
wound healing
|
GO:0042060 |
122 |
0.027
|
|
|
|
respiratory system process
|
GO:0003016 |
3 |
0.027
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
263 |
0.027
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.027
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
136 |
0.027
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
58 |
0.026
|
|
|
|
response to calcium ion
|
GO:0051592 |
59 |
0.026
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
37 |
0.026
|
|
|
|
organ morphogenesis
|
GO:0009887 |
75 |
0.026
|
Fly |
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.026
|
|
|
|
regulation of anion transport
|
GO:0044070 |
43 |
0.026
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.026
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.026
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
163 |
0.026
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
47 |
0.026
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
74 |
0.026
|
|
|
|
gtp catabolic process
|
GO:0006184 |
71 |
0.026
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
126 |
0.025
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
134 |
0.025
|
|
|
|
response to ethanol
|
GO:0045471 |
162 |
0.025
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
4 |
0.025
|
|
|
|
dephosphorylation
|
GO:0016311 |
98 |
0.025
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
1 |
0.025
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.025
|
|
|
|
response to peptide
|
GO:1901652 |
292 |
0.025
|
|
|
|
myelination
|
GO:0042552 |
39 |
0.025
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
44 |
0.025
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.025
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
172 |
0.025
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.025
|
|
|
|
ventricular cardiac muscle cell action potential
|
GO:0086005 |
2 |
0.024
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.024
|
|
|
|
gtp metabolic process
|
GO:0046039 |
72 |
0.024
|
|
|
|
acetylcholine secretion neurotransmission
|
GO:0014055 |
4 |
0.024
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
3 |
0.024
|
|
|
|
cell fate determination
|
GO:0001709 |
2 |
0.024
|
|
|
|
regulation of defense response
|
GO:0031347 |
68 |
0.024
|
|
|
|
response to estradiol
|
GO:0032355 |
164 |
0.024
|
Rat |
|
|
regulation of gtpase activity
|
GO:0043087 |
57 |
0.024
|
|
|
|
defense response
|
GO:0006952 |
194 |
0.024
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
70 |
0.024
|
|
|
|
cell cycle process
|
GO:0022402 |
57 |
0.023
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
83 |
0.023
|
Rat |
|
|
adenosine receptor signaling pathway
|
GO:0001973 |
7 |
0.023
|
|
|
|
regulation of respiratory gaseous exchange
|
GO:0043576 |
2 |
0.023
|
|
