Rattus norvegicus

0 known processes

Zwint

ZW10 interactor

(Aliases: Sip30,Zwint-1)

Zwint biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.223
macromolecular complex assembly GO:0065003 273 0.193
cellular response to peptide hormone stimulus GO:0071375 120 0.190
rna metabolic process GO:0016070 406 0.174
cation transport GO:0006812 382 0.173
protein complex assembly GO:0006461 263 0.143
regulation of nucleic acid templated transcription GO:1903506 380 0.140
response to peptide GO:1901652 292 0.124
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.120
cellular response to nitrogen compound GO:1901699 210 0.113
protein complex subunit organization GO:0071822 302 0.112
macromolecular complex subunit organization GO:0043933 339 0.111
regulation of transcription dna templated GO:0006355 374 0.107
cellular response to organonitrogen compound GO:0071417 197 0.096
regulation of rna biosynthetic process GO:2001141 381 0.093
histamine secretion involved in inflammatory response GO:0002441 3 0.091
negative regulation of multicellular organismal process GO:0051241 203 0.087
negative regulation of gene expression GO:0010629 199 0.087
cellular response to oxygen containing compound GO:1901701 386 0.087
protein complex biogenesis GO:0070271 263 0.083
negative regulation of metabolic process GO:0009892 331 0.082
nucleic acid templated transcription GO:0097659 379 0.081
protein heterooligomerization GO:0051291 89 0.080
negative regulation of cellular metabolic process GO:0031324 281 0.078
negative regulation of macromolecule metabolic process GO:0010605 260 0.078
rna biosynthetic process GO:0032774 380 0.077
transcription dna templated GO:0006351 377 0.077
cellular response to peptide GO:1901653 133 0.076
ion transmembrane transport GO:0034220 365 0.067
cellular response to hormone stimulus GO:0032870 247 0.066
negative regulation of rna metabolic process GO:0051253 123 0.065
protein oligomerization GO:0051259 191 0.064
cellular component biogenesis GO:0044085 368 0.062
metal ion transport GO:0030001 289 0.061
histamine secretion by mast cell GO:0002553 3 0.060
cation transmembrane transport GO:0098655 263 0.060
regulation of hormone levels GO:0010817 187 0.056
regulation of rna metabolic process GO:0051252 391 0.055
single organism intracellular transport GO:1902582 166 0.052
neuron differentiation GO:0030182 368 0.051
response to inorganic substance GO:0010035 377 0.051
defense response GO:0006952 194 0.051
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.051
intracellular signal transduction GO:0035556 314 0.050
cellular component assembly GO:0022607 360 0.050
cellular protein localization GO:0034613 122 0.050
transcription from rna polymerase ii promoter GO:0006366 252 0.050
inorganic ion transmembrane transport GO:0098660 229 0.050
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.049
catabolic process GO:0009056 351 0.049
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.049
immune system process GO:0002376 204 0.048
positive regulation of transcription dna templated GO:0045893 197 0.048
regulation of protein metabolic process GO:0051246 289 0.048
regulation of protein transport GO:0051223 68 0.047
homeostatic process GO:0042592 331 0.047
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.046
negative regulation of biosynthetic process GO:0009890 168 0.045
negative regulation of nucleic acid templated transcription GO:1903507 117 0.044
positive regulation of biosynthetic process GO:0009891 319 0.044
regulation of signal transduction GO:0009966 318 0.043
inflammatory response GO:0006954 150 0.043
transmembrane transport GO:0055085 412 0.043
intracellular transport GO:0046907 185 0.042
regulation of ion transport GO:0043269 245 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
protein transport GO:0015031 132 0.042
secretion by cell GO:0032940 248 0.041
regulation of cell differentiation GO:0045595 320 0.041
regulation of metal ion transport GO:0010959 118 0.041
inorganic cation transmembrane transport GO:0098662 202 0.041
establishment of protein localization GO:0045184 141 0.040
brain development GO:0007420 247 0.040
lysosome localization GO:0032418 10 0.040
proteolysis GO:0006508 175 0.040
negative regulation of cell development GO:0010721 82 0.040
regulation of molecular function GO:0065009 398 0.040
oxoacid metabolic process GO:0043436 290 0.039
cell morphogenesis GO:0000902 142 0.039
negative regulation of cell differentiation GO:0045596 99 0.039
secretion GO:0046903 307 0.039
negative regulation of nervous system development GO:0051961 79 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
response to nutrient levels GO:0031667 370 0.038
macromolecule localization GO:0033036 252 0.038
vesicle mediated transport GO:0016192 181 0.037
negative regulation of cellular biosynthetic process GO:0031327 161 0.037
regulation of catalytic activity GO:0050790 304 0.036
negative regulation of developmental process GO:0051093 125 0.036
negative regulation of neurogenesis GO:0050768 78 0.035
central nervous system development GO:0007417 311 0.035
regulation of programmed cell death GO:0043067 341 0.035
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
cellular response to insulin stimulus GO:0032869 81 0.034
myeloid leukocyte mediated immunity GO:0002444 12 0.034
regulation of cell development GO:0060284 263 0.033
head development GO:0060322 247 0.033
regulation of cellular protein metabolic process GO:0032268 267 0.032
mast cell activation GO:0045576 15 0.032
immune response GO:0006955 104 0.031
signal release GO:0023061 145 0.031
negative regulation of response to stimulus GO:0048585 155 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.031
organic acid metabolic process GO:0006082 292 0.030
organelle organization GO:0006996 266 0.030
positive regulation of signaling GO:0023056 270 0.030
cellular macromolecule localization GO:0070727 122 0.030
positive regulation of protein metabolic process GO:0051247 178 0.029
cellular response to stress GO:0033554 269 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.028
learning or memory GO:0007611 90 0.028
negative regulation of transport GO:0051051 136 0.028
multi organism reproductive process GO:0044703 262 0.028
response to insulin GO:0032868 133 0.028
regulation of ion transmembrane transport GO:0034765 121 0.028
neuron development GO:0048666 286 0.028
calcium ion transport GO:0006816 131 0.028
response to peptide hormone GO:0043434 278 0.028
regulation of nervous system development GO:0051960 264 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
negative regulation of protein metabolic process GO:0051248 114 0.027
nitrogen compound transport GO:0071705 229 0.027
regulation of ion transmembrane transporter activity GO:0032412 48 0.027
regulation of neuron differentiation GO:0045664 208 0.027
negative regulation of rna biosynthetic process GO:1902679 118 0.027
regulation of apoptotic process GO:0042981 335 0.026
regulation of neurogenesis GO:0050767 247 0.026
response to metal ion GO:0010038 253 0.026
protein localization GO:0008104 191 0.026
leukocyte activation involved in immune response GO:0002366 16 0.026
organic substance catabolic process GO:1901575 316 0.026
negative regulation of transcription dna templated GO:0045892 116 0.025
regulation of transporter activity GO:0032409 50 0.025
calcium ion transmembrane transport GO:0070588 70 0.024
response to extracellular stimulus GO:0009991 380 0.024
chemical homeostasis GO:0048878 292 0.024
positive regulation of gene expression GO:0010628 244 0.024
regulation of phosphorylation GO:0042325 248 0.024
macromolecule catabolic process GO:0009057 58 0.023
protein targeting GO:0006605 61 0.023
immune effector process GO:0002252 53 0.023
positive regulation of catalytic activity GO:0043085 184 0.023
single organism cellular localization GO:1902580 102 0.023
regulation of cell projection organization GO:0031344 175 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
cellular cation homeostasis GO:0030003 180 0.022
regulation of transmembrane transport GO:0034762 122 0.022
myeloid leukocyte activation GO:0002274 36 0.022
regulation of cell morphogenesis GO:0022604 77 0.022
intracellular protein transport GO:0006886 79 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.021
protein phosphorylation GO:0006468 345 0.021
hormone transport GO:0009914 121 0.021
divalent metal ion transport GO:0070838 132 0.021
regulation of neuron projection development GO:0010975 161 0.021
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
exocytosis GO:0006887 60 0.020
cytoplasmic transport GO:0016482 115 0.020
negative regulation of cellular protein metabolic process GO:0032269 106 0.020
neuron projection development GO:0031175 273 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
cellular homeostasis GO:0019725 252 0.020
organophosphate metabolic process GO:0019637 370 0.020
response to wounding GO:0009611 254 0.020
cellular component morphogenesis GO:0032989 155 0.020
purine containing compound metabolic process GO:0072521 253 0.020
multicellular organism reproduction GO:0032504 233 0.020
cell cell signaling GO:0007267 335 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
regulation of protein modification process GO:0031399 194 0.019
response to corticosteroid GO:0031960 235 0.019
positive regulation of molecular function GO:0044093 230 0.019
apoptotic process GO:0006915 381 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.018
response to growth factor GO:0070848 189 0.018
programmed cell death GO:0012501 392 0.018
mitochondrion organization GO:0007005 35 0.018
hormone secretion GO:0046879 115 0.018
leukocyte activation GO:0045321 76 0.018
single organism reproductive process GO:0044702 297 0.018
cell activation involved in immune response GO:0002263 16 0.018
response to hypoxia GO:0001666 231 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
reproductive process GO:0022414 372 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
regulation of cell proliferation GO:0042127 359 0.018
establishment of protein localization to organelle GO:0072594 44 0.018
mast cell mediated immunity GO:0002448 10 0.018
cellular amine metabolic process GO:0044106 38 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
microtubule organizing center organization GO:0031023 1 0.018
cellular response to organic cyclic compound GO:0071407 202 0.017
regulation of cellular component organization GO:0051128 368 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
cellular response to lipid GO:0071396 201 0.017
carboxylic acid metabolic process GO:0019752 289 0.017
sexual reproduction GO:0019953 148 0.017
single organism biosynthetic process GO:0044711 342 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
cellular catabolic process GO:0044248 295 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
nucleotide biosynthetic process GO:0009165 98 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
ion homeostasis GO:0050801 212 0.016
divalent inorganic cation transport GO:0072511 134 0.016
cellular chemical homeostasis GO:0055082 247 0.015
regulation of anatomical structure size GO:0090066 135 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
cell activation GO:0001775 97 0.015
mast cell degranulation GO:0043303 10 0.015
positive regulation of smoothened signaling pathway GO:0045880 1 0.015
multicellular organism growth GO:0035264 1 0.015
centrosome organization GO:0051297 1 0.015
positive regulation of signal transduction GO:0009967 175 0.015
calcium ion homeostasis GO:0055074 162 0.015
protein homooligomerization GO:0051260 91 0.015
cell projection morphogenesis GO:0048858 123 0.015
negative regulation of neuron projection development GO:0010977 46 0.015
nucleobase biosynthetic process GO:0046112 2 0.015
cell projection organization GO:0030030 302 0.015
negative regulation of signaling GO:0023057 157 0.015
negative regulation of cell communication GO:0010648 158 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
positive regulation of protein modification process GO:0031401 142 0.015
response to carbohydrate GO:0009743 183 0.015
regulation of protein phosphatase type 2a activity GO:0034047 2 0.015
cellular ketone metabolic process GO:0042180 51 0.015
ras protein signal transduction GO:0007265 29 0.015
organelle localization GO:0051640 55 0.015
single organism catabolic process GO:0044712 283 0.014
histamine production involved in inflammatory response GO:0002349 3 0.014
ribonucleotide biosynthetic process GO:0009260 85 0.014
positive regulation of cell death GO:0010942 184 0.014
cation homeostasis GO:0055080 195 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
protein localization to organelle GO:0033365 57 0.014
production of molecular mediator involved in inflammatory response GO:0002532 5 0.014
regulation of protein kinase activity GO:0045859 105 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
myeloid cell activation involved in immune response GO:0002275 13 0.014
reproduction GO:0000003 245 0.014
regulation of proteolysis GO:0030162 66 0.013
positive regulation of cell communication GO:0010647 271 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
cellular response to metal ion GO:0071248 55 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
regulation of protein targeting GO:1903533 28 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
blood circulation GO:0008015 183 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
locomotion GO:0040011 237 0.013
regulation of growth GO:0040008 105 0.013
gamete generation GO:0007276 124 0.013
circulatory system development GO:0072359 134 0.013
negative regulation of molecular function GO:0044092 133 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
spindle organization GO:0007051 2 0.013
cardiac ventricle development GO:0003231 1 0.013
leukocyte degranulation GO:0043299 12 0.012
regulation of system process GO:0044057 208 0.012
regulation of nucleocytoplasmic transport GO:0046822 28 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
neuron projection morphogenesis GO:0048812 122 0.012
protein processing GO:0016485 68 0.012
negative regulation of cell death GO:0060548 229 0.012
response to hexose GO:0009746 144 0.012
nuclear transport GO:0051169 49 0.012
response to estrogen GO:0043627 232 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
carbohydrate homeostasis GO:0033500 75 0.012
cellular response to alcohol GO:0097306 87 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.011
response to decreased oxygen levels GO:0036293 237 0.011
regulation of transmembrane transporter activity GO:0022898 49 0.011
regulation of hydrolase activity GO:0051336 143 0.011
negative regulation of protein transport GO:0051224 17 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of protein localization GO:0032880 81 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
response to hydrogen peroxide GO:0042542 89 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
response to glucocorticoid GO:0051384 223 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
regulated secretory pathway GO:0045055 17 0.011
localization of cell GO:0051674 202 0.011
regulation of epithelial to mesenchymal transition GO:0010717 2 0.011
protein catabolic process GO:0030163 30 0.011
negative regulation of signal transduction GO:0009968 83 0.011
cognition GO:0050890 92 0.011
monosaccharide metabolic process GO:0005996 61 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
response to oxygen levels GO:0070482 265 0.011
regulation of transferase activity GO:0051338 123 0.011
mitochondrial transport GO:0006839 19 0.010
mesoderm development GO:0007498 2 0.010
regeneration GO:0031099 163 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
metal ion homeostasis GO:0055065 186 0.010
positive regulation of cell development GO:0010720 176 0.010
cellular amide metabolic process GO:0043603 44 0.010
positive regulation of transport GO:0051050 245 0.010
leukocyte mediated immunity GO:0002443 28 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010
cell part morphogenesis GO:0032990 123 0.010
response to cytokine GO:0034097 215 0.010
carbohydrate derivative metabolic process GO:1901135 346 0.010
sodium ion transport GO:0006814 82 0.010
response to oxidative stress GO:0006979 186 0.010

Zwint disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.046
sensory system disease DOID:0050155 0 0.015
disease of metabolism DOID:0014667 0 0.012
central nervous system disease DOID:331 0 0.011