Rattus norvegicus

0 known processes

Pxk

PX domain containing serine/threonine kinase

(Aliases: MGC114238)

Pxk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.140
organophosphate metabolic process GO:0019637 370 0.123
Mouse
carbohydrate derivative metabolic process GO:1901135 346 0.092
Mouse
single organism catabolic process GO:0044712 283 0.085
Mouse
programmed cell death GO:0012501 392 0.084
nucleobase containing small molecule metabolic process GO:0055086 316 0.074
Mouse
lipid metabolic process GO:0006629 283 0.072
cellular response to endogenous stimulus GO:0071495 377 0.069
apoptotic process GO:0006915 381 0.069
carboxylic acid metabolic process GO:0019752 289 0.067
catabolic process GO:0009056 351 0.063
Mouse
cellular lipid metabolic process GO:0044255 208 0.061
regulation of phosphate metabolic process GO:0019220 349 0.061
Mouse
ribonucleotide metabolic process GO:0009259 231 0.060
Mouse
macromolecular complex assembly GO:0065003 273 0.060
organic substance catabolic process GO:1901575 316 0.060
Mouse
organic acid metabolic process GO:0006082 292 0.058
regulation of cellular protein metabolic process GO:0032268 267 0.056
macromolecular complex subunit organization GO:0043933 339 0.054
cellular component assembly GO:0022607 360 0.054
regulation of programmed cell death GO:0043067 341 0.054
purine ribonucleotide metabolic process GO:0009150 227 0.053
Mouse
nucleoside phosphate metabolic process GO:0006753 283 0.052
Mouse
cellular response to hormone stimulus GO:0032870 247 0.050
organelle organization GO:0006996 266 0.048
oxoacid metabolic process GO:0043436 290 0.048
positive regulation of response to stimulus GO:0048584 285 0.047
cation transport GO:0006812 382 0.047
positive regulation of phosphate metabolic process GO:0045937 262 0.047
regulation of rna metabolic process GO:0051252 391 0.045
positive regulation of signaling GO:0023056 270 0.045
purine containing compound metabolic process GO:0072521 253 0.043
Mouse
protein complex subunit organization GO:0071822 302 0.042
ribose phosphate metabolic process GO:0019693 235 0.042
Mouse
regulation of molecular function GO:0065009 398 0.041
Mouse
transmembrane transport GO:0055085 412 0.041
nucleotide metabolic process GO:0009117 279 0.041
Mouse
cellular component biogenesis GO:0044085 368 0.040
protein complex biogenesis GO:0070271 263 0.040
intracellular signal transduction GO:0035556 314 0.040
amine metabolic process GO:0009308 38 0.040
cellular ketone metabolic process GO:0042180 51 0.039
regulation of cellular component organization GO:0051128 368 0.039
nucleoside metabolic process GO:0009116 179 0.038
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 141 0.038
Mouse
protein complex assembly GO:0006461 263 0.038
negative regulation of macromolecule metabolic process GO:0010605 260 0.038
response to peptide GO:1901652 292 0.038
cellular response to peptide GO:1901653 133 0.038
cell projection organization GO:0030030 302 0.038
cellular amino acid metabolic process GO:0006520 107 0.037
negative regulation of metabolic process GO:0009892 331 0.037
Mouse
response to peptide hormone GO:0043434 278 0.037
regulation of phosphorylation GO:0042325 248 0.037
ribonucleoside metabolic process GO:0009119 174 0.036
Mouse
negative regulation of cell death GO:0060548 229 0.036
cellular response to oxygen containing compound GO:1901701 386 0.036
regulation of multicellular organismal development GO:2000026 376 0.036
regulation of protein metabolic process GO:0051246 289 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.036
protein phosphorylation GO:0006468 345 0.034
organonitrogen compound catabolic process GO:1901565 179 0.034
Mouse
cellular catabolic process GO:0044248 295 0.034
Mouse
immune response GO:0006955 104 0.033
purine nucleotide metabolic process GO:0006163 229 0.033
Mouse
organophosphate catabolic process GO:0046434 148 0.033
Mouse
regulation of secretion GO:0051046 224 0.033
behavior GO:0007610 205 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.033
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
organophosphate biosynthetic process GO:0090407 143 0.032
single organism organelle organization GO:1902589 180 0.032
cellular amine metabolic process GO:0044106 38 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
nitrogen compound transport GO:0071705 229 0.031
homeostatic process GO:0042592 331 0.031
regulation of cell proliferation GO:0042127 359 0.031
secretion GO:0046903 307 0.030
regulation of intracellular signal transduction GO:1902531 218 0.030
carboxylic acid transport GO:0046942 115 0.030
organic acid transport GO:0015849 116 0.030
macromolecule localization GO:0033036 252 0.030
organonitrogen compound biosynthetic process GO:1901566 167 0.030
ion transmembrane transport GO:0034220 365 0.029
transcription from rna polymerase ii promoter GO:0006366 252 0.029
regulation of cell differentiation GO:0045595 320 0.029
regulation of apoptotic process GO:0042981 335 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.029
Mouse
positive regulation of molecular function GO:0044093 230 0.029
glycosyl compound metabolic process GO:1901657 182 0.028
Mouse
cellular response to organonitrogen compound GO:0071417 197 0.028
single organism reproductive process GO:0044702 297 0.028
regulation of nucleic acid templated transcription GO:1903506 380 0.028
response to nutrient levels GO:0031667 370 0.028
regulation of nervous system development GO:0051960 264 0.027
aging GO:0007568 241 0.027
carbohydrate derivative catabolic process GO:1901136 147 0.026
Mouse
rna biosynthetic process GO:0032774 380 0.026
response to extracellular stimulus GO:0009991 380 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
Mouse
regulation of neurogenesis GO:0050767 247 0.026
multicellular organism reproduction GO:0032504 233 0.026
regulation of cellular catabolic process GO:0031329 101 0.026
Mouse
organic cyclic compound catabolic process GO:1901361 175 0.026
Mouse
cellular response to nitrogen compound GO:1901699 210 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.025
transcription dna templated GO:0006351 377 0.025
heterocycle catabolic process GO:0046700 167 0.025
Mouse
nucleotide catabolic process GO:0009166 139 0.025
Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.025
Mouse
regulation of cellular amine metabolic process GO:0033238 8 0.025
rna metabolic process GO:0016070 406 0.025
positive regulation of developmental process GO:0051094 283 0.025
defense response GO:0006952 194 0.024
Human
response to inorganic substance GO:0010035 377 0.024
lipid biosynthetic process GO:0008610 128 0.024
purine nucleoside metabolic process GO:0042278 169 0.024
Mouse
response to external biotic stimulus GO:0043207 221 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
positive regulation of cell communication GO:0010647 271 0.024
response to hexose GO:0009746 144 0.024
cellular response to stress GO:0033554 269 0.024
carbohydrate derivative biosynthetic process GO:1901137 124 0.023
protein localization GO:0008104 191 0.023
ion homeostasis GO:0050801 212 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
cellular chemical homeostasis GO:0055082 247 0.023
cellular response to lipid GO:0071396 201 0.022
protein oligomerization GO:0051259 191 0.022
positive regulation of programmed cell death GO:0043068 157 0.022
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
response to ethanol GO:0045471 162 0.022
organic anion transport GO:0015711 132 0.022
protein transport GO:0015031 132 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
nucleotide biosynthetic process GO:0009165 98 0.022
regulation of catalytic activity GO:0050790 304 0.022
Mouse
regulation of nucleotide metabolic process GO:0006140 117 0.022
Mouse
anion transport GO:0006820 178 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
single organism intracellular transport GO:1902582 166 0.021
Rat
neuron differentiation GO:0030182 368 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
neuron projection development GO:0031175 273 0.021
signal release GO:0023061 145 0.021
purine nucleotide catabolic process GO:0006195 136 0.021
Mouse
regulation of cell development GO:0060284 263 0.021
negative regulation of protein metabolic process GO:0051248 114 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
regulation of signal transduction GO:0009966 318 0.021
positive regulation of apoptotic process GO:0043065 154 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
Mouse
neuron development GO:0048666 286 0.020
regulation of purine nucleotide metabolic process GO:1900542 115 0.020
Mouse
metal ion transport GO:0030001 289 0.020
regulation of protein modification process GO:0031399 194 0.020
purine nucleoside triphosphate metabolic process GO:0009144 141 0.020
Mouse
reproduction GO:0000003 245 0.020
signal transduction by phosphorylation GO:0023014 144 0.020
regulation of system process GO:0044057 208 0.020
nucleoside triphosphate catabolic process GO:0009143 123 0.020
Mouse
positive regulation of protein metabolic process GO:0051247 178 0.020
regulation of transcription dna templated GO:0006355 374 0.020
glycerolipid metabolic process GO:0046486 67 0.020
nucleoside triphosphate metabolic process GO:0009141 144 0.020
Mouse
organic hydroxy compound metabolic process GO:1901615 115 0.020
response to other organism GO:0051707 220 0.019
regulation of vesicle mediated transport GO:0060627 81 0.019
chemical homeostasis GO:0048878 292 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
rhythmic process GO:0048511 156 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
Mouse
nucleoside catabolic process GO:0009164 126 0.019
Mouse
response to hypoxia GO:0001666 231 0.019
neurological system process GO:0050877 219 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
nucleic acid templated transcription GO:0097659 379 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
reproductive process GO:0022414 372 0.018
nucleoside phosphate biosynthetic process GO:1901293 102 0.018
oxidation reduction process GO:0055114 304 0.018
regulation of cellular localization GO:0060341 263 0.018
intracellular transport GO:0046907 185 0.018
Rat
positive regulation of cell proliferation GO:0008284 249 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
positive regulation of secretion GO:0051047 140 0.018
ras protein signal transduction GO:0007265 29 0.018
regulation of phosphorus metabolic process GO:0051174 349 0.018
Mouse
positive regulation of phosphorylation GO:0042327 177 0.018
regulation of lipid metabolic process GO:0019216 68 0.018
positive regulation of transport GO:0051050 245 0.018
purine nucleoside catabolic process GO:0006152 124 0.018
Mouse
glycosyl compound catabolic process GO:1901658 126 0.017
Mouse
negative regulation of gene expression GO:0010629 199 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
purine containing compound catabolic process GO:0072523 138 0.017
Mouse
blood circulation GO:0008015 183 0.017
central nervous system development GO:0007417 311 0.017
regulation of hormone levels GO:0010817 187 0.017
neuron death GO:0070997 127 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
cellular homeostasis GO:0019725 252 0.017
negative regulation of developmental process GO:0051093 125 0.017
positive regulation of signal transduction GO:0009967 175 0.017
anterior posterior pattern specification GO:0009952 1 0.017
positive regulation of cell death GO:0010942 184 0.017
vesicle mediated transport GO:0016192 181 0.017
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.017
Mouse
negative regulation of transport GO:0051051 136 0.017
Mouse
response to growth factor GO:0070848 189 0.017
cell type specific apoptotic process GO:0097285 134 0.017
mapk cascade GO:0000165 140 0.017
cellular macromolecule localization GO:0070727 122 0.017
proteolysis GO:0006508 175 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.016
Mouse
regulation of kinase activity GO:0043549 117 0.016
ribonucleotide biosynthetic process GO:0009260 85 0.016
positive regulation of cell development GO:0010720 176 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
head development GO:0060322 247 0.016
enzyme linked receptor protein signaling pathway GO:0007167 116 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
Mouse
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
cation transmembrane transport GO:0098655 263 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
ribonucleoside catabolic process GO:0042454 126 0.016
Mouse
regulation of protein phosphorylation GO:0001932 183 0.016
response to cytokine GO:0034097 215 0.015
cellular response to abiotic stimulus GO:0071214 85 0.015
multi organism reproductive process GO:0044703 262 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
alcohol metabolic process GO:0006066 77 0.015
synaptic transmission GO:0007268 235 0.015
Mouse
response to decreased oxygen levels GO:0036293 237 0.015
regulation of membrane potential GO:0042391 110 0.015
response to nutrient GO:0007584 248 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
establishment of protein localization GO:0045184 141 0.015
regulation of hydrolase activity GO:0051336 143 0.015
Mouse
response to oxygen levels GO:0070482 265 0.015
response to insulin GO:0032868 133 0.015
response to mechanical stimulus GO:0009612 134 0.015
alpha amino acid metabolic process GO:1901605 71 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
response to metal ion GO:0010038 253 0.015
regulation of catabolic process GO:0009894 113 0.015
Mouse
response to acid chemical GO:0001101 222 0.015
cellular component morphogenesis GO:0032989 155 0.015
cellular protein localization GO:0034613 122 0.015
immune system process GO:0002376 204 0.014
phospholipid metabolic process GO:0006644 61 0.014
cellular response to external stimulus GO:0071496 118 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
multicellular organism growth GO:0035264 1 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.014
positive regulation of catabolic process GO:0009896 78 0.014
reproductive system development GO:0061458 128 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
Mouse
regulation of neuron differentiation GO:0045664 208 0.014
circulatory system process GO:0003013 183 0.014
negative regulation of signaling GO:0023057 157 0.014
tube development GO:0035295 89 0.014
guanosine containing compound catabolic process GO:1901069 71 0.014
regulation of synaptic transmission GO:0050804 141 0.014
Mouse
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
gtp catabolic process GO:0006184 71 0.014
regulation of neuron projection development GO:0010975 161 0.014
gonad development GO:0008406 104 0.014
endocytosis GO:0006897 84 0.014
developmental process involved in reproduction GO:0003006 159 0.014
positive regulation of gene expression GO:0010628 244 0.014
cellular ion homeostasis GO:0006873 184 0.014
gtp metabolic process GO:0046039 72 0.013
cell cell signaling GO:0007267 335 0.013
Mouse
regulation of nucleoside metabolic process GO:0009118 66 0.013
Mouse
response to biotic stimulus GO:0009607 226 0.013
inflammatory response GO:0006954 150 0.013
Human
carbohydrate metabolic process GO:0005975 130 0.013
purine ribonucleotide biosynthetic process GO:0009152 81 0.013
axis specification GO:0009798 4 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
purine nucleotide biosynthetic process GO:0006164 83 0.013
regulation of immune system process GO:0002682 123 0.013
response to camp GO:0051591 91 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
Mouse
peptidyl amino acid modification GO:0018193 126 0.013
single organism cellular localization GO:1902580 102 0.013
regulation of blood pressure GO:0008217 83 0.013
regulation of homeostatic process GO:0032844 101 0.013
regulation of mapk cascade GO:0043408 116 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
response to oxidative stress GO:0006979 186 0.013
cell part morphogenesis GO:0032990 123 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
tissue development GO:0009888 252 0.012
response to bacterium GO:0009617 200 0.012
positive regulation of protein modification process GO:0031401 142 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
b cell differentiation GO:0030183 2 0.012
positive regulation of nervous system development GO:0051962 178 0.012
response to estrogen GO:0043627 232 0.012
anion transmembrane transport GO:0098656 77 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
cation homeostasis GO:0055080 195 0.012
regulation of immunoglobulin production GO:0002637 4 0.012
amide transport GO:0042886 105 0.012
regulation of cell projection organization GO:0031344 175 0.012
hormone secretion GO:0046879 115 0.012
metal ion homeostasis GO:0055065 186 0.012
secretion by cell GO:0032940 248 0.012
single organism behavior GO:0044708 130 0.012
regulation of cell adhesion GO:0030155 52 0.012
feeding behavior GO:0007631 53 0.012
response to glucose GO:0009749 136 0.012
guanosine containing compound metabolic process GO:1901068 74 0.011
regulation of hormone secretion GO:0046883 106 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
response to tumor necrosis factor GO:0034612 56 0.011
hormone transport GO:0009914 121 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
localization of cell GO:0051674 202 0.011
cognition GO:0050890 92 0.011
cytoplasmic transport GO:0016482 115 0.011
Rat
steroid metabolic process GO:0008202 73 0.011
aromatic compound catabolic process GO:0019439 168 0.011
Mouse
response to carbohydrate GO:0009743 183 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
Mouse
response to estradiol GO:0032355 164 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
lipid modification GO:0030258 52 0.011
cellular response to alcohol GO:0097306 87 0.011
embryonic pattern specification GO:0009880 1 0.011
axon development GO:0061564 96 0.011
sexual reproduction GO:0019953 148 0.011
positive regulation of immune response GO:0050778 42 0.011
negative regulation of cell development GO:0010721 82 0.011
small molecule biosynthetic process GO:0044283 124 0.011
regulation of secretion by cell GO:1903530 208 0.011
lipid transport GO:0006869 61 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
cell morphogenesis GO:0000902 142 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
Mouse
cardiovascular system development GO:0072358 134 0.011
spindle organization GO:0007051 2 0.011
regulation of anatomical structure size GO:0090066 135 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
hormone metabolic process GO:0042445 69 0.011
regulation of immune response GO:0050776 55 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
brain development GO:0007420 247 0.010
regulation of response to external stimulus GO:0032101 106 0.010
regulation of proteolysis GO:0030162 66 0.010
positive regulation of gtpase activity GO:0043547 47 0.010
peptide transport GO:0015833 97 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
dna metabolic process GO:0006259 96 0.010
insulin like growth factor receptor signaling pathway GO:0048009 3 0.010
positive regulation of secretion by cell GO:1903532 128 0.010
growth GO:0040007 165 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
bmp signaling pathway GO:0030509 4 0.010
cell fate determination GO:0001709 2 0.010
circadian rhythm GO:0007623 88 0.010
response to dexamethasone GO:0071548 49 0.010

Pxk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
sensory system disease DOID:0050155 0 0.012